Lior Zangi | Drug Discovery and Development | Best Researcher Award

Lior Zangi | Drug Discovery and Development | Best Researcher Award

Prof. Lior Zangi, Icahn School of Medicine at Mount Sinai, United States

Prof. Lior Zangi is an Associate Professor of Cardiology and Genetics & Genomic Sciences at the Icahn School of Medicine at Mount Sinai, NY. He earned his Ph.D. in Immunology from the Weizmann Institute and completed postdoctoral training at Harvard Medical School. Renowned for his pioneering work in mRNA-based cardiovascular therapies, Prof. Zangi has received prestigious awards including the AHA Postdoctoral Fellowship and an endowed professorship in Cardiovascular Research. He is a founding board member of the Society for RNA Therapeutics and actively contributes to global scientific councils, manuscript reviews, and grant panels.

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Education

Prof. Lior Zangi 🎓 began his academic journey with a B.Sc. in Biology from the Hebrew University, Givat-Ram, Jerusalem in 2000. He then earned his M.Sc. in Experimental and Developmental Medicine in 2003 from the Hebrew University Hadassah-Medical School under the guidance of Prof. Raphael Gorodetsky. In 2009, he completed his Ph.D. in Immunology at the Weizmann Institute of Science, mentored by Prof. Yair Reisner. 🌿 He continued his training as a postdoctoral fellow at Sheba Medical Center (2009–2010) under Prof. Benjamin Dekel and later at Harvard Medical School (2010–2014) with Professors Derrick Rossi and Kenneth Chien.

Awards

Prof. Lior Zangi 🌟 has earned numerous prestigious honors throughout his career. He received the ASH Travel Award in both 2008 and 2009 🧳, and in 2009, was granted a Postdoctoral Fellowship Award by the Israeli Budgeting Committee and Planning. In 2012, he was honored with both the ISSCR Travel Award and R&D Systems Travel Grant ✈️. His groundbreaking postdoctoral work earned him the AHA Fellowship Award in 2014 🫀. In 2017, he received the Mount Sinai Faculty Idea Prize 🧠, and in 2019, his research on mRNA therapy was recognized as highly influential 📜. In 2023, he was awarded the Endowed Chan Soon-Shiong Professorship in Cardiovascular Research 🏅.

Research Focus

Prof. Lior Zangi is a pioneering researcher in cardiovascular regenerative medicine, with a special focus on modified mRNA therapies, 🧬 stem cell biology, and 🫀 cardiac regeneration. His work centers on developing innovative strategies for repairing damaged heart tissue using modRNA, induced pluripotent stem cells (iPSCs), and heart-on-chip technologies. Zangi’s groundbreaking research has contributed to advancements in treating conditions like myocardial infarction and Barth syndrome, and has broad implications for tissue engineering, 💉 protein replacement therapy, and immune modulation. His contributions are reshaping modern precision medicine and offering new hope for heart failure patients worldwide.

Publication Top Notes

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

Isolation of mesenchymal stem cells from G-CSF-mobilized human peripheral blood using fibrin microbeads

Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells

A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells

Isolation and characterization of nontubular sca-1+ lin− multipotent stem/progenitor cells from adult mouse kidney

Pkm2 regulates cardiomyocyte cell cycle and promotes cardiac regeneration

mRNA-based protein replacement therapy for the heart

Altering sphingolipid metabolism attenuates cell death and inflammatory response after myocardial infarction

Nitika Mor | Drug Discovery and Development | Best Researcher Award

Nitika Mor | Drug Discovery and Development | Best Researcher Award

Dr. Nitika Mor, Baba Mastnath University, Asthal Bohar, Rohtak (HR), India

Dr. Nitika Mor is an accomplished Assistant Professor of Chemistry at Baba Mastnath University, Rohtak, with a Ph.D. in Pharmaceutical Chemistry from Kurukshetra University. Her research focuses on drug delivery systems, traditional medicinal formulations, and molecular docking. She has published 14 research papers, authored a book chapter, holds two patent publications (one granted), and has received multiple awards including the UGC-CSIR JRF/SRF and Best Poster Award. With technical expertise in synthesis, biological assays, and in-silico studies, Dr. Mor is a dynamic contributor to pharmaceutical research and innovation.

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Education

Dr. Nitika Mor is a dedicated researcher with a Ph.D. in Chemistry from Kurukshetra University (2017–2022), where she focused her thesis on the Design, Characterization, and In-Vitro Studies of Sustained Release Delivery Systems for Curcumin under the guidance of Dr. Neera Raghav. 🎓 She holds an M.Sc. in Organic Chemistry (2013–2015) from Hindu College, Sonipat, affiliated with Maharishi Dayanand University, Rohtak. 🧪 Her academic journey began with a B.Sc. in Physics, Chemistry, and Mathematics (2010–2013) from Hindu Girls College, Sonipat. 📚 Dr. Mor’s educational background reflects a strong foundation in science and innovative pharmaceutical research.

Experience

Dr. Nitika Mor is currently serving as an Assistant Professor in the Department of Chemistry at Baba Mastnath University, Rohtak, since February 1, 2023. 🏛️ With her strong academic foundation and research expertise in pharmaceutical and organic chemistry, she brings innovative teaching methods and deep subject knowledge to the classroom. 🧪 Her role involves mentoring students, delivering engaging lectures, and contributing to the academic growth of the department. 📚 Dr. Mor’s commitment to education and passion for chemistry make her a valuable asset to the university’s faculty. ✨ She continues to inspire budding scientists through her teaching and guidance.

Awards

Dr. Nitika Mor has received several prestigious awards and fellowships in recognition of her academic excellence and research potential. She qualified the UGC-CSIR JRF (Chemical Sciences) in June 2016 with an impressive All India Rank of 65. 🇮🇳 She was awarded the Junior Research Fellowship (JRF) from October 2017 to September 2019, followed by the Senior Research Fellowship (SRF) from October 2019 to March 2022 by UGC-CSIR India to support her Ph.D. journey. 🔬 In 2018, she received the Best Poster Presentation Award at the 9th National Conference on RACES-2018 held at MMM College, Patiala, Punjab.

Research Focus

Dr. Nitika Mor specializes in pharmaceutical and biomedical sciences, with a strong research focus on natural polymer-based oral drug delivery systems. Her work emphasizes the use of biopolymers like cellulose, pectin, carrageenan, and alginate for sustained release formulations, particularly for curcumin. She explores modifications of polysaccharides and curcumin derivatives to improve bioavailability, pharmacokinetics, and therapeutic efficacy. Her contributions also span phytochemistry, investigating medicinal plants like Ashwagandha and Garlic for their pharmacological benefits. Dr. Mor integrates green chemistry, molecular modeling, and clinical insights into her innovative drug delivery strategies.

Publication Top Notes

Recent advances in cellulose, pectin, carrageenan and alginate-based oral drug delivery systems

Some cetyltrimethylammonium bromide modified polysaccharide supports as sustained release systems for curcumin

Design and development of carboxymethylcellulose ester of curcumin as sustained release delivery system in liver

Synthesis of propynyloxy substituted some novel aurones as potent cathepsin B inhibitors

Alginate hydrogels: Sustained release system to analyze the effect of traditional excipients on curcumin availability

Study on enhanced serum protein protecting and anti-cathepsin activities of various curcumin formulations containing traditional excipients and bio-enhancers

In-vitro simulation of modified-alginate ester as sustained release delivery system for curcumin

Curcumin, the panacea: A review on advancement to solve pharmaco-kinetic problems.

A review: Phytochemicals and bioactivities of Ashwagandha (Withania somnifera).