Takuma Hayashi | Oncology Pharmaceuticals | Best Researcher Award

Takuma Hayashi | Oncology Pharmaceuticals | Best Researcher Award

Prof. Dr. Takuma Hayashi, National Hospital Organization Kyoto Medical Center, Japan

Prof. Dr. Takuma Hayashi is a renowned Japanese physician-scientist specializing in gynecologic oncology. 🎓 He earned his PhD from the University of Tokyo and trained at MIT’s Whitehead Institute 🧠, contributing to Nobel-linked research. Currently a professor at Shinshu University and Section Head at Kyoto Medical Center 🏥, his groundbreaking work on uterine leiomyosarcoma (LMS) identified LMP2 deficiency as a key biomarker 🔎. Through precision medicine and genomic profiling 🧬, his research has significantly advanced diagnostics and treatment strategies for LMS. With over 30 years of funded research, Dr. Hayashi is globally recognized for revolutionizing women’s cancer care.

Publication Profile

Scopus

Education

Prof. Dr. Takuma Hayashi is a distinguished physician-scientist known for bridging fundamental cancer research with clinical applications. 👨‍⚕️🔬 He is a Professor at Shinshu University Graduate School of Medicine and Section Head at Japan’s National Hospital Organization Kyoto Medical Center. 🎓🏥 Dr. Hayashi earned his PhD from the University of Tokyo and completed postdoctoral training at MIT’s Whitehead Institute under Dr. Rick A. Young. 🎓🇯🇵🇺🇸 He contributed to Nobel Prize-linked AIDS vaccine research with Dr. David Baltimore. With over 30 years of NIH and JSPS funding, his work focuses on molecular research in uterine leiomyosarcoma and ovarian cancer, collaborating with Nobel Laureate Dr. Susumu Tonegawa.

Experience

Prof. Dr. Takuma Hayashi has pioneered precision medicine breakthroughs in uterine leiomyosarcoma (LMS) treatment. 🧬💉 His team used cancer genome panel testing to tailor therapies based on each tumor’s unique genetics. For example, immunotherapy with pembrolizumab led to significant tumor regression, while targeted treatment with pazopanib stabilized disease for months. 🎯💊 Dr. Hayashi’s background from the University of Tokyo and MIT supports his innovative approach. 🚀 His ongoing goals include developing diagnostics, launching clinical trials, expanding global collaboration, and improving patient access to genomic profiling. 🌍💡 His work offers new hope for women facing this aggressive cancer.

Research Focus

Prof. Dr. Takuma Hayashi’s research primarily focuses on molecular oncology and infectious diseases, particularly cancer biomarkers and viral infections. 🧬🔬 His work on uterine leiomyosarcoma involves discovering key diagnostic biomarkers like LMP2 to improve early detection and treatment strategies in aggressive cancers. 🩺🎗️ Additionally, Dr. Hayashi explores infectious diseases such as avian influenza and COVID-19, emphasizing the One Health approach to prevent viral spread between animals and humans. 🦠🌍 His interdisciplinary research bridges cancer biology, immunology, and public health, aiming to develop precision medicine therapies and enhance global disease control efforts.

Publication Top Notes

THE ROLE OF LIVE BIRD MARKETS SHOULD BE EMPHASIZED IN PREVENTING THE SPREAD OF HIGHLY PATHOGENIC AVIAN INFLUENZA INFECTIONS

THE IMPORTANCE OF ONE HEALTH IN PREVENTING THE SPREAD OF HIGHLY PATHOGENIC AVIAN INFLUENZA/H5N1

Efficacy and Tolerability of Olaparib Plus Paclitaxel in Patients with Gastric Cancer Associated with Hereditary Breast and Ovarian Cancer

DEVELOPMENT OF ENDOSALPINGIOSIS IN PATIENTS WITH A HISTORY OF BREAST CANCER

High Transferability of Neutralizing Antibodies against SARS-CoV-2 to Umbilical Cord Blood in Pregnant Women Vaccinated with BNT162b2 XBB.1.5: A Retrospective Cohort Study

POTENTIAL DIAGNOSTIC BIOMARKERS FOR HUMAN MESENCHYMAL TUMORS, ESPECIALLY LMP2/Β1I AND CYCLIN E1/MIB1 DIFFERENTIAL EXPRESSION: PRUM-IBIO STUDY

Assoc Prof Dr. Shereen ElAzzazy|Oncology Pharmaceuticals|Best Researcher Award

Assoc Prof Dr. Shereen ElAzzazy|Oncology Pharmaceuticals|Best Researcher Award

Assoc Prof Dr. Shereen ElAzzazy at HMC, QU, WHO,Qatar

PROFILE  

orcid

Google scholar

Early Academic Pursuits 🎓

The foundation of this individual’s career is rooted in a strong academic background. Although specific details about early education are not mentioned, the advanced roles undertaken in both pharmaceutical and medical sectors suggest a deep understanding and expertise in pharmacology, clinical pharmacy, and sterile medication preparation. Their professional journey likely began with formal education in pharmacy, complemented by continuous professional development and specialized training. The fact that they were entrusted with high-responsibility roles, such as acting pharmacy director, regulatory manager, and clinical instructor, indicates a robust educational foundation coupled with a commitment to lifelong learning.

Their association with the SAAD Training Institute, affiliated with Duke University, is an important academic highlight. This affiliation points to their exposure to global standards in pharmaceutical education and practices, which undoubtedly shaped their approach to teaching and developing competencies within their professional network.

Professional Endeavors 🏥

SAAD Specialist Hospital, Saudi Arabia (Dec 2003 – Jun 2006)
This phase of the career showcases the breadth and depth of their professional experience in Saudi Arabia’s healthcare system, particularly within SAAD Specialist Hospital, a prominent medical institution. Initially starting as a Pediatric Clinical Pharmacist in 2003, they quickly rose through the ranks to take on more senior and specialized roles.

  • Education and Development Coordinator (Dec 2005 – Jun 2006): In this role, they focused on the educational advancement of the hospital’s healthcare professionals. This position required overseeing staff training and ensuring adherence to the latest pharmaceutical guidelines and practices, fostering an environment of continual learning and improvement.
  • Aseptic Technology Instructor, SAAD Training Institute (Jun 2004 – Jun 2006): As an instructor, they were responsible for training both pharmacists and non-pharmacists in aseptic techniques, particularly in the preparation of sterile medications. The affiliation with Duke University highlights the high standard of education and training delivered.
  • IV Room Supervisor (Jun 2004 – Jun 2006): Managing the IV Room, they oversaw sterile medication preparation for neonates, pediatric, and adult patients, dealing with complex formulations such as Total Parenteral Nutrition (TPN), chemotherapy drugs, and desensitization protocols.

These roles reflect a strong command over clinical pharmacy, sterile practices, and pharmaceutical education, making them a critical contributor to healthcare improvement in Saudi Arabia.

Governmental Hospital of Tropical Diseases, Ministry of Health, Egypt (Dec 1997 – Dec 2003)
Their role at this governmental hospital in Egypt demonstrates significant leadership and management skills within the pharmaceutical services sector.

  • Inpatient Pharmacist (Dec 1997 – Sep 2002): During this period, they were entrusted with the pharmaceutical care of inpatient services, managing medication therapy and ensuring safe medication administration.
  • Acting Pharmacy Director (Oct 2002 – Dec 2003): As Acting Pharmacy Director, they assumed full authority over the hospital’s pharmacy operations. This role required balancing clinical duties with administrative responsibilities, overseeing drug inventories, ensuring compliance with pharmaceutical regulations, and leading the pharmacy staff.

This progression in Egypt’s healthcare sector speaks to their competence, leadership abilities, and the trust placed in them to manage essential healthcare operations.

CBIC Medical, Pharmaceutical Development, and Consultation Company (Nov 2002 – Dec 2003)
In parallel with their role in Egypt’s healthcare system, they also held a position in CBIC Medical, which involved regulatory and marketing responsibilities in the pharmaceutical sector.

  • Regulatory and Marketing Manager: They were tasked with navigating complex pharmaceutical regulations while overseeing the marketing of medical products. This role required a deep understanding of both the regulatory landscape and market dynamics.
  • Clinical and Marketing Instructor: Leveraging their extensive pharmaceutical knowledge, they conducted training programs for medical representatives, teaching them about new products and re-launched products, as well as imparting advanced marketing strategies.

This role illustrates their ability to work across both clinical and commercial spheres, bridging the gap between product development, regulatory compliance, and market outreach.

Contributions and Research Focus 🔬

While explicit research endeavors are not mentioned, their extensive work in teaching, sterile medication preparation, and regulatory roles highlights a career deeply rooted in evidence-based practices. Their focus on educating healthcare professionals in critical areas like aseptic techniques and sterile medication preparation indicates a dedication to improving healthcare outcomes through rigorous training.

The supervisory roles in sterile medication preparation, particularly for vulnerable populations such as neonates and pediatric patients, point to a keen interest in precision pharmacy and patient safety, areas likely to have been influenced by research in clinical pharmacology.

Accolades and Recognition 🏅

The trust and leadership roles assigned to them—ranging from being an Acting Pharmacy Director to a supervisor and instructor at the SAAD Specialist Hospital—reflect the high regard in which they were held by their peers and employers. Their instructional role at the SAAD Training Institute, affiliated with Duke University, is a significant marker of their expertise and the recognition they received in the field of pharmaceutical education.

Impact and Influence 🌍

Their influence spans multiple facets of healthcare, particularly in the realms of education, clinical pharmacy, and sterile medication practices. Through teaching roles, both at SAAD and CBIC Medical, they shaped the competencies of numerous healthcare professionals, directly impacting patient safety and care quality.

As a supervisor in the preparation of sterile medications, they ensured that some of the most vulnerable patients—neonates and those undergoing chemotherapy—received safe, effective treatments. This role would have had a profound impact on patient outcomes, underscoring their influence in clinical settings.

Legacy and Future Contributions 📜

Their legacy is marked by the high standards of training and education they provided, particularly in aseptic techniques and sterile medication preparation. The knowledge they imparted to medical representatives and pharmacy staff will continue to influence healthcare practices long after their direct involvement.

🎓Publication 

Patterns of onset and resolution of immune‐related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced …

  • Authors   :Jeffrey S Weber, Reinhard Dummer, Veerle de Pril, Celeste Lebbé, F Stephen Hodi, MDX010‐20 Investigators
  • Journal    : Cancer
  • Year         :2013

An evaluation of pharmacist contribution to an oncology ward in a Swedish hospital

  • Authors   :Eva Rämme Bremberg, Christina Hising, Urban Nylén, Hans Ehrsson, Staffan Eksborg
  • Journal    :Journal of Oncology Pharmacy Practice
  • Year         :2006

The role of the pharmacist in the multidisciplinary approach to the prevention and resolution of drug-related problems in cancer chemotherapy

  • Authors   : Ahmet S Boşnak, Nevzat Birand, Ömer Diker, Abdikarim Abdi, Bilgen Başgut
  • Journal    :Journal of Oncology Pharmacy Practice
  • Year         :2019

Denosumab in hypercalcemia of malignancy: a case series

  • Authors   : Amanda Dietzek, Kelly Connelly, Michael Cotugno, Sylvia Bartel, Anne M McDonnell
  • Journal    :Journal of Oncology Pharmacy Practice
  • Year         :2015

Chinese herbal medicine for reducing chemotherapy-associated side-effects in breast cancer patients: a systematic review and meta-analysis

  • Authors   :Sha Li, Tsz-him So, Guoyi Tang, Hor-Yue Tan, Ning Wang, Bacon Fung Leung Ng, Chris Kam Wa Chan, Edwin Chau-Leung Yu, Yibin Feng
  • Journal    :Frontiers in Oncology
  • Year         :2020

Dr. Marc Bender|Immunotherapy |Best Researcher Award

Dr. Marc Bender|Pharmaceutical Chemistry |Best Researcher Award|

Dr. Marc Bender at abriz University of Medical Sciences, Iran

PROFILE  

orcid

Early Academic Pursuits 📚

Marc Bender’s academic journey began with a strong foundation in molecular biology, earning a (link unavailable) and (link unavailable) from Universität Hamburg. He furthered his expertise by pursuing a doctorate in skin cancer research at the department of dermatology, Elbe Klinikum Buxtehude. His thesis focused on elucidating molecular mechanisms, particularly epigenetic regulation via miRNAs, involved in tumor progression of cutaneous squamous cell carcinoma.

Professional Endeavors 💼

As a data scientist, Marc contributed to the European melanoma registry (EUMelaReg), evaluating retrospective data for real-world clinical trials. This experience deepened his understanding of melanoma and immunotherapy, and he developed skills in statistical methods and programming. His professional endeavors have been marked by a commitment to advancing cancer research and treatment.

Contributions and Research Focus 🔬

Marc’s research focus encompasses various aspects of skin cancer, including:

– Investigating effects of combined UVA, UVB, visible light, and infrared radiation on human skin cells (KAUVIR)
– Examining the influence of UVA and UVB irradiation on human dermal stem cells (UV-DHDS)
– Comparing treatments for melanoma, including anti-PD1 monotherapy and BRAF/MEK inhibitor treatment (PDSeq and EMRSeq)
– Analyzing immune checkpoint inhibitor maintenance treatment after achieving a partial or complete response (EUMelaReg)

Accolades and Recognition 🏆

Marc’s work has been recognized through publications in esteemed journals, including:

– Journal of Cancer Research and Clinical Oncology
– Journal of Photochemistry and Photobiology B Biology
– Cancers (MDPI)
– Journal of Clinical Oncology (conference paper)
– Annals of Oncology (conference paper)

Impact and Influence 🌟

Marc’s research has contributed significantly to the understanding of skin cancer mechanisms and treatment options. His work has:

– Advanced knowledge of miRNA expression and its association with tumor progression
– Investigated treatment adherence in patients with stage III melanoma
– Compared outcomes of different treatment approaches for metastatic melanoma

Legacy and Future Contributions 🌱

As a dedicated researcher, Marc continues to contribute to the field of skin cancer research. His future endeavors will likely focus on:

– Furthering understanding of molecular mechanisms in skin cancer
– Developing innovative treatment approaches
– Collaborating with international researchers to advance cancer research

Marc’s legacy will be marked by his commitment to advancing cancer research, improving treatment options, and enhancing patient outcomes. His work will continue to influence the scientific community, inspiring future generations of researchers.

🎓Publication 

Real-World Therapy with Pembrolizumab: Outcomes and Surrogate Endpoints for Predicting Survival in Advanced Melanoma Patients in Germany

  • Authors   : Marc Bender
  • Journal    :Cancers
  • Year         :2022

UVB damage response of dermal stem cells as melanocyte precursors compared to keratinocytes, melanocytes, and fibroblasts from human foreskin

  • Authors   :Marc Bender
  • Journal    :Photochemistry and Photobiology B: Biology
  • Year         :2021

UV-type specific alteration of miRNA expression and its association with tumor progression and metastasis in SCC cell lines

  • Authors   : Marc Bender
  • Journal    :Cancer Research and Clinical Oncologyy
  • Year         :2020

 

Dr.Long Pang |Oncology Pharmaceuticals| Best Researcher Award-1332

Dr.Long Pang|Oncology Pharmaceuticals |Best Researcher Award|

Dr.Long Pang at Xi’an Medical University, China

PROFILE  

scopus

Early Academic Pursuits 📚

Long Pang was born in Gansu, China, where he developed an early passion for science and innovation. His academic journey began with a focus on veterinary science, where he pursued a Master of Science (M.S.) degree at Northwest Agricultural and Forestry University in Yangling, Shaanxi, China. Completing his M.S. in July 2012, Pang demonstrated an exceptional commitment to his studies and research in veterinary science, laying the groundwork for his future endeavors in animal biotechnology. In August 2012, he advanced his academic career by enrolling in a Ph.D. program at the same university. During his Ph.D. studies, he specialized in Animal Biotechnology, a field that encompasses the use of biotechnological tools for the improvement of animal health and productivity. He completed his Ph.D. in July 2016, marking the beginning of a promising career in biomedical research.

Professional Endeavors 🏢

After earning his Ph.D., Long Pang joined Xi’an Medical University as an Associate Professor in the School of Basic Medical Science. His professional career is distinguished by his innovative research in the areas of microfluidics and single-cell analysis. At Xi’an Medical University, Pang quickly established himself as a leading researcher, focusing on the development of microfluidic chips and their applications in single-cell analysis and organ-on-a-chip technology. His work has been instrumental in advancing the understanding of cellular mechanics and tumor microenvironments, contributing significantly to the fields of biomedical engineering and cancer research.

Contributions and Research Focus 🔬

Long Pang’s research primarily revolves around microfluidics-based single-cell analysis and organ-on-a-chip technologies. His work has led to the development of innovative microfluidic devices that allow for the manipulation and analysis of single cells in a highly controlled environment. These devices have broad applications in cancer research, particularly in studying tumor microenvironments and the behavior of cancer stem cells. One of his significant contributions includes the development of a microfluidic chip for glioma stem cell sorting and single-cell-derived tumor sphere assays. This research has provided valuable insights into the formation of tumor spheres and the role of the tumor microenvironment in cancer progression.

Pang has also been involved in projects aimed at integrating microfluidic platforms with other technologies to enhance the precision and efficiency of single-cell analysis. His research has been supported by several prestigious grants, including those from the National Science Foundation of China and the Fundamental Research Foundation of Xi’an Medical University. Notably, he has led projects such as the study of heterotypic single-cell-derived tumor-sphere formation using an integrated microfluidics platform, which has garnered significant attention and funding.

Accolades and Recognition 🏆

Long Pang’s contributions to the field of biomedical research have been widely recognized. His work has resulted in over 21 publications in high-impact journals, including TRAC-Trends in Analytical Chemistry, Analytical Chemistry, and Sensors & Actuators B: Chemical. He has also authored a chapter in the Handbook of Single-Cell Technologies, published by Springer, highlighting his expertise in digital microfluidics for single-cell manipulation and analysis. In addition to his publications, Pang has been granted two Chinese patents related to his innovations in microfluidic technology, further establishing his reputation as a leading researcher in his field.

Pang’s achievements have also been acknowledged through various editorial appointments. He has served as a Youth Editorial Board Member of Glioma and the E-Journal of Translational Medicine, where he has contributed to the advancement of research dissemination and knowledge sharing in the scientific community. His contributions to the academic community extend beyond research, as he is an active member of several professional organizations, including the Shaanxi Pharmacology Association, the Chinese Society of Micro-Nano Technology (CSMNT), and the Chinese Chemistry Society (CCS).

Impact and Influence 🌍

The impact of Long Pang’s research extends beyond academia. His work on microfluidic devices has the potential to revolutionize the way single-cell analysis is conducted, offering new tools for researchers and clinicians in the diagnosis and treatment of diseases, particularly cancer. His contributions to the development of organ-on-a-chip technology are also significant, providing a platform for more accurate and efficient drug testing, which could lead to more effective treatments for various diseases.

Pang’s research has influenced a new generation of scientists and engineers, inspiring them to explore the possibilities of microfluidics and its applications in biomedical research. His collaborations with other leading researchers and institutions, both in China and internationally, have further expanded the reach of his work, fostering innovation and knowledge exchange in the global scientific community.

Legacy and Future Contributions 🚀

Long Pang’s legacy in the field of biomedical research is characterized by his innovative approach to solving complex problems in cell biology and medicine. His contributions to the development of microfluidic technology and single-cell analysis tools have set new standards in the field, paving the way for future research and innovation. As he continues his work at Xi’an Medical University, Pang remains committed to advancing the frontiers of biomedical engineering, with a focus on developing new technologies that can improve human health and well-being.

Looking to the future, Long Pang’s ongoing research projects, such as the construction of a 3D microenvironment for single-cell level tumor cells, promise to yield further breakthroughs in our understanding of cancer and other diseases. His work is likely to continue to influence the field for years to come, as he mentors the next generation of researchers and contributes to the global effort to improve healthcare through technological innovation.

🎓Publication 

Tumor microenvironment-derived exosomes-assisted single-cell-derived tumor-sphere formation and drug-resistance by a microfluidic system

Construction of multiple concentration gradients for single-cell level drug screening

Droplets microfluidics platform—A tool for single cell research

Microfluidics-Based Single-Cell Research for Intercellular Interaction

Digital Microfluidics for Single Cell Manipulation and Analysis

  • Authors   :Pang, L., Ding, J., Fan, S.-K.
  • Journal    :Handbook of Single-Cell Technologies
  • Year         :2021