Ruifen Sun | Drug Discovery and Development | Women Researcher Award

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Prof. Ruifen Sun | Drug Discovery and Development | Women Researcher Award

Yunnan University of Chinese Medicine | China

Prof. Ruifen Sun is a nationally recognized academic leader, medical doctor, and senior nursing scholar whose work has made a significant impact on integrated traditional Chinese and Western medicine, particularly in the prevention and treatment of tumors and other major diseases. She serves as Professor, Doctoral Supervisor, and Postdoctoral Supervisor, and is widely acknowledged as a national-level first-class professional leader in nursing education. Prof. Sun is the Head of the Master’s Program in Nursing and leads Yunnan Province’s first-class discipline of Integrated Traditional Chinese and Western Medicine Nursing, where she has played a pivotal role in shaping disciplinary development, curriculum innovation, and high-level talent cultivation.With an extensive research portfolio, Prof. Sun has published more than forty SCI-indexed papers and holds both an authorized invention patent and an authorized utility model patent, reflecting her strong capacity for scientific innovation and translational research. She has led numerous nationally and provincially funded research projects, teams, and academic platforms, including major initiatives supported by the National Natural Science Foundation of China. Her research integrates theoretical exploration with clinical application, bridging traditional Chinese medicine nursing practices and modern biomedical approaches.Prof. Sun is an active participant in the global academic community, having delivered oral presentations and engaged in scholarly exchanges at leading international conferences across Europe and North America. She has also served as a state-sponsored visiting scholar at a major medical center in the United States, further strengthening her international academic vision. Beyond academia, she is a member of the National Traditional Chinese Medicine Standards Advisory Expert Database and a distinguished young talent under Yunnan Province’s high-level talent program. She has additionally contributed to regional governance through public service leadership roles. Currently, she serves as Dean of the School of Nursing at Yunnan University of Traditional Chinese Medicine and leads its Overseas Students Association, continuing to influence nursing education, research excellence, and international collaboration.

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Featured Publications

Ruby Anto | Drug Discovery and Development | Best Researcher Award

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Dr. Ruby Anto | Drug Discovery and Development | Best Researcher Award

Centre of Excellence in Nutraceuticals | India

Dr. Ruby Anto is a distinguished biochemist and cancer researcher with an extensive career dedicated to advancing the fields of molecular oncology, bioimmunotherapy, and nutraceutical science. She currently serves as Chief Scientist at the Centre of Excellence in Nutraceuticals, KSCSTE, Government of Kerala, Thiruvananthapuram, and Honorary Scientist at the Institute of Advanced Virology, Thiruvananthapuram. Over her accomplished career, she has held numerous scientific positions at the Rajiv Gandhi Centre for Biotechnology, progressing from Research Associate to Scientist G, reflecting her consistent contributions and leadership in biomedical research.Dr. Anto earned her PhD in Biochemistry from Amala Cancer Research Centre, Thrissur, following her postgraduate studies in Chemistry and Education. Her multidisciplinary academic background—combining chemistry, biochemistry, and pedagogy—has been central to her innovative approach to cancer biology and molecular medicine. Her early academic achievements and later professional experiences at prestigious institutions such as the M.D. Anderson Cancer Center, Houston, provided a strong foundation for her research on targeted cancer therapies, chemopreventive agents, and the role of natural products in disease modulation.Recognized nationally and internationally for her scientific excellence, Dr. Anto has received several prestigious honors, including the Young National Women Bio-Scientist Award from the Department of Biotechnology, Government of India, and fellowships from the National Academy of Sciences, India, and the Academy of Sciences, Thiruvananthapuram. Her professional journey also includes global training experiences, such as her participation in the Clinical Trials Traineeship Program at INSERM, Paris, which broadened her expertise in translational research and clinical validation of nutraceutical interventions.As a mentor, Dr. Anto has nurtured a generation of young scientists, with her students and postdoctoral fellows earning numerous national and international awards for their work in cancer biology and nutraceutical research. Her leadership has fostered a thriving academic environment focused on the discovery and characterization of bioactive compounds from natural sources with therapeutic potential.Dr. Anto’s scientific publications have advanced understanding in areas such as natural compound-mediated cancer prevention, signaling pathway modulation, and anti-inflammatory mechanisms of nutraceuticals. Through her research, she continues to bridge the gap between basic biochemistry and applied health sciences, promoting nutraceutical innovation as a cornerstone of preventive and personalized medicine. Her lifelong dedication to scientific inquiry and mentorship underscores her status as one of India’s leading voices in biochemistry and nutraceutical research.

Profile: Google Scholar

Featured Publications

Ruby, A. J., Kuttan, G., Babu, K. D., Rajasekharan, K. N., & Kuttan, R. (1995). Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Letters, 94(1), 79–83.

Anto, R. J., Mukhopadhyay, A., Denning, K., & Aggarwal, B. B. (2002). Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis, 23(1), 143–150.

Anto, R. J., Sukumaran, K., Kuttan, G., Rao, M. N. A., Subbaraju, V., & Kuttan, R. (1995). Anticancer and antioxidant activity of synthetic chalcones and related compounds. Cancer Letters, 97(1), 33–37.

Oommen, S., Anto, R. J., Srinivas, G., & Karunagaran, D. (2004). Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells. European Journal of Pharmacology, 485(1–3), 97–103.*

Anto, R. J., Mukhopadhyay, A., Shishodia, S., Gairola, C. G., & Aggarwal, B. B. (2002). Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: Correlation with induction of cyclooxygenase-2. Carcinogenesis, 23(9), 1511–1518.*

Bava, S. V., Puliappadamba, V. T., Deepti, A., Nair, A., Karunagaran, D., & Anto, R. J. (2005). Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization. Journal of Biological Chemistry, 280(8), 6301–6308.*

Srinivas, G., Anto, R. J., Srinivas, P., Vidhyalakshmi, S., Senan, V. P., & Karunagaran, D. (2003). Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. European Journal of Pharmacology, 473(2–3), 117–125.*

Katiane – Medicinal Chemistry – Best Researcher Award

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Katiane - Medicinal Chemistry - Best Researcher Award

UFPE - Brazil

Introduction

Katiane Cruz Magalhães Xavier is a dedicated researcher in the field of chemistry, with a particular focus on inorganic chemistry, materials science, and environmental applications. Her academic journey has led her to explore a wide range of topics, including the activation of clays for industrial applications, the use of natural materials for oil clarification, and the development of sustainable solutions for biotechnological purposes. Currently pursuing a PhD in Chemistry at the Federal University of Pernambuco (UFPE), her work continues to push the boundaries of chemical research with an emphasis on both academic and practical outcomes.

Inorganic Chemistry and Clay Activation

Katiane's research on the thermal activation of palygorskite, a natural clay mineral, has contributed significantly to the field of inorganic chemistry. Her work on using thermally activated palygorskite to clarify soybean oil, published in Applied Clay Science (2016), has garnered attention for its potential to improve industrial processes related to oil purification. This study not only highlights the utility of clay materials but also presents an environmentally friendly alternative to conventional oil clarification methods.

Materials Science and Surface Modifications

Katiane has also made substantial contributions to materials science, particularly in understanding the effects of acid treatment on clay minerals. Her collaborative research, featured in Materials Research (2014), examined how acid treatment alters the surface area, morphology, and chemical composition of palygorskite, paving the way for more efficient applications of clays in various industries. These insights are crucial for the development of enhanced materials that are both functional and sustainable.

Environmental and Biotechnological Applications

As part of her doctoral research at UFPE, Katiane is exploring the use of macroalgae from the Pernambuco coast. Her project, titled Macroalgae from the Pernambuco Coast: From the Use of Crude Extracts to Electrospun Films for Biotechnological Applications, focuses on harnessing the biotechnological potential of marine resources. By creating electrospun films from macroalgae extracts, she aims to develop innovative materials for use in various biotechnological fields, including medicine, environmental science, and materials engineering.

Oil Purification and Environmental Sustainability

Katiane's work on oil clarification extends beyond traditional chemical methods and emphasizes environmentally sustainable approaches. Her research into using thermally activated clays, particularly in the context of soybean oil purification, offers a green alternative to chemical treatments. This work aligns with global trends in minimizing the environmental impact of industrial processes and contributes to the development of cleaner technologies in the food and pharmaceutical industries.

Interdisciplinary Research in Chemistry

Katiane's research is rooted in the intersection of several disciplines, including inorganic chemistry, materials science, and environmental chemistry. Her ability to bridge these areas allows for a holistic approach to problem-solving, addressing both practical and theoretical challenges. This interdisciplinary methodology has equipped her with the skills to develop solutions that are not only scientifically sound but also applicable in real-world scenarios.

Conclusion

Katiane Cruz Magalhães Xavier’s academic and research career has been defined by her commitment to advancing the fields of inorganic chemistry, materials science, and biotechnological applications. Through her innovative work on clay activation, oil clarification, and macroalgae-based materials, she continues to contribute valuable knowledge that could have far-reaching implications in both industrial and environmental sectors. As a doctoral candidate at UFPE, her research promises to further enhance our understanding of natural materials and their potential for sustainable development.

NOTABLE PUBLICATION

Thermally activated palygorskites as agents to clarify soybean oil

Effects of acid treatment on the clay palygorskite: XRD, surface area, morphological and chemical composition

Zhao-Jie Wang – Medicinal Chemistry – Best Researcher Award

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Zhao-Jie Wang - Medicinal Chemistry - Best Researcher Award

Yunnan Normal University - China

Introduction

Dr. Zhao-Jie Wang is an eminent researcher in the field of natural products, medicinal chemistry, and pharmacology. With an extensive portfolio of over 33 SCI-indexed publications, Dr. Wang has made substantial contributions to understanding antimicrobial compounds, drug development, and therapeutic strategies against multidrug-resistant pathogens. His research bridges phytochemistry and pharmacology, offering innovative solutions to pressing challenges in infectious diseases and antimicrobial resistance.

Antimicrobial Natural Products

Dr. Wang has extensively studied bioactive compounds derived from plants and fungi to combat multidrug-resistant bacteria and fungi. His work, featured in leading journals like Journal of Ethnopharmacology and Food Chemistry: X, provides a comprehensive analysis of plant-based antimicrobial agents, their chemical compositions, and mechanisms of action. His studies on Zanthoxylum species and Sigesbeckia orientalis are pivotal in discovering new therapeutic agents.

Multidrug-Resistant Bacterial Infections

A significant aspect of Dr. Wang's research focuses on developing novel strategies to address multidrug-resistant (MDR) bacterial infections. His study on light-controllable chitosan micelles for bacterial biofilm treatment, published in Carbohydrate Polymers (IF=11.2), exemplifies his innovative approach. This research provides a promising avenue for combating MDR bacteria using advanced nanotechnology.

Phytochemical Analysis and Bioactivity

Dr. Wang has explored the phytochemistry of various herbs and their bioactivity against pathogens. His work includes detailed characterization of chemical constituents using LC-MS and their evaluation for antibacterial, antifungal, and nematicidal activities. Studies published in Journal of Agricultural and Food Chemistry and Heliyon highlight his expertise in bridging traditional herbal medicine with modern pharmacology.

Therapeutic Strategies for Infectious Diseases

With a focus on infectious diseases, Dr. Wang has proposed innovative therapeutic strategies to combat intracellular MDR bacteria. His study published in the Journal of Controlled Release (IF=10.8) offers groundbreaking insights into targeted drug delivery systems and their potential to improve therapeutic efficacy against challenging infections.

Bioactivity-Driven Drug Development

Dr. Wang’s research on bioactivity-driven isolation and characterization of antifungal and antibacterial compounds has significantly contributed to drug development. Studies on compounds such as diterpenoids, ent-kaurane diterpenes, and formononetin derivatives underscore his efforts in identifying potential therapeutic agents for osteoclast regulation and bacterial resistance management.

Conclusion

Dr. Zhao-Jie Wang's diverse and impactful research continues to advance the understanding of natural products, antimicrobial pharmacology, and innovative therapeutic approaches. His multidisciplinary expertise and commitment to addressing global health challenges have established him as a leading figure in the field of pharmacology and medicinal chemistry. Through his work, Dr. Wang aims to contribute to the development of safer and more effective treatments for drug-resistant pathogens, ensuring a brighter future for global healthcare.

NOTABLE PUBLICATION

Siegesoxylipin A‒J, previously undescribed phyto-oxylipins inhibition of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci from Sigesbeckia orientalis

Diterpenoids of Caryopteris trichosphaera W. W. Sm. inhibiting MRSA and VRE in vitro and in vivo.

Oleanolic acid derivatives against drug-resistant bacteria and fungi by multi-targets to avoid drug resistance

Phytocannabinoid-like meroterpenoids from twigs and leaves of Rhododendron spinuliferum

New resorcylic acid derivatives of Lysimachia tengyuehensis against MRSA and VRE by interfering with bacterial metabolic imbalance

Rahul K. Reddy – Pharmacology – Excellence in Research

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Rahul K. Reddy - Pharmacology - Excellence in Research

Lautoka Hospital - Fiji

Introduction

Rahul K. Reddy is an accomplished researcher and medical professional specializing in urology, surgery, and trauma care. With a focus on advancing medical understanding and clinical outcomes in challenging cases, Dr. Reddy has contributed significantly to the fields of laparoscopic surgery, burn care, and acute surgical conditions. His work is characterized by its depth of clinical insight and dedication to improving patient outcomes in diverse healthcare settings, particularly in Fiji.

Laparoscopic Surgery in Urology

Dr. Reddy's pioneering work in the laparoscopic excision of seminal vesicle cystadenoma underscores his expertise in minimally invasive surgical techniques. Published in Urology Case Reports (2019), this study has provided valuable insights into rare urological conditions, offering innovative approaches to their management.

Burn Injury Characteristics and Outcomes

In collaboration with a multidisciplinary team, Dr. Reddy conducted an in-depth analysis of burn injury patterns and treatment outcomes at Lautoka Hospital. His findings, featured in Burns Open (2024), have contributed to the optimization of burn care protocols in resource-limited settings, enhancing recovery rates and patient care quality.

Acute Appendicitis Management

Through an observational retrospective study on acute appendicitis at Lautoka Aspen Hospital, Dr. Reddy explored the clinical characteristics and outcomes over a one-year period (2022–2023). Published in World Journal of Surgical Research (2024), this research offers evidence-based recommendations for improving appendicitis management in Pacific Island healthcare systems.

Rare Tumors and Pathologies

Dr. Reddy has also delved into the study of rare pathologies, such as primary epithelioid hemangioendothelioma of the kidney pelvis. His case report, published in the American Journal of Surgery and Clinical Case Reports (2020), adds to the limited literature on this rare tumor type, emphasizing the importance of early diagnosis and tailored surgical interventions.

Trauma and Emergency Medicine

With a holistic approach to trauma care, Dr. Reddy's research addresses the critical needs of patients in emergency settings. His work highlights the significance of multidisciplinary collaboration and protocol-driven management in achieving favorable outcomes for complex trauma cases.

Conclusion

Rahul K. Reddy’s extensive research portfolio reflects his unwavering commitment to advancing medical science and improving patient care. By addressing diverse challenges in urology, surgery, and trauma care, Dr. Reddy continues to contribute to the development of innovative treatments and clinical best practices, with a lasting impact on global and regional healthcare.

NOTABLE PUBLICATION

Laparoscopic excision of seminal vesicle cystadenoma 2019 (4)

Burns injury characteristics and outcomes at lautoka hospital, fiji 2024

Characteristics and Outcomes of Acute Appendicitis in Lautoka Aspen Hospital, Fiji: An Observational Retrospective Study (09/22–09/23) 2024

Primary Epithelioid Hemangioendothelioma of the Kidney Pelvis 2020