Ruby Anto | Drug Discovery and Development | Best Researcher Award

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Dr. Ruby Anto | Drug Discovery and Development | Best Researcher Award

Centre of Excellence in Nutraceuticals | India

Dr. Ruby Anto is a distinguished biochemist and cancer researcher with an extensive career dedicated to advancing the fields of molecular oncology, bioimmunotherapy, and nutraceutical science. She currently serves as Chief Scientist at the Centre of Excellence in Nutraceuticals, KSCSTE, Government of Kerala, Thiruvananthapuram, and Honorary Scientist at the Institute of Advanced Virology, Thiruvananthapuram. Over her accomplished career, she has held numerous scientific positions at the Rajiv Gandhi Centre for Biotechnology, progressing from Research Associate to Scientist G, reflecting her consistent contributions and leadership in biomedical research.Dr. Anto earned her PhD in Biochemistry from Amala Cancer Research Centre, Thrissur, following her postgraduate studies in Chemistry and Education. Her multidisciplinary academic background—combining chemistry, biochemistry, and pedagogy—has been central to her innovative approach to cancer biology and molecular medicine. Her early academic achievements and later professional experiences at prestigious institutions such as the M.D. Anderson Cancer Center, Houston, provided a strong foundation for her research on targeted cancer therapies, chemopreventive agents, and the role of natural products in disease modulation.Recognized nationally and internationally for her scientific excellence, Dr. Anto has received several prestigious honors, including the Young National Women Bio-Scientist Award from the Department of Biotechnology, Government of India, and fellowships from the National Academy of Sciences, India, and the Academy of Sciences, Thiruvananthapuram. Her professional journey also includes global training experiences, such as her participation in the Clinical Trials Traineeship Program at INSERM, Paris, which broadened her expertise in translational research and clinical validation of nutraceutical interventions.As a mentor, Dr. Anto has nurtured a generation of young scientists, with her students and postdoctoral fellows earning numerous national and international awards for their work in cancer biology and nutraceutical research. Her leadership has fostered a thriving academic environment focused on the discovery and characterization of bioactive compounds from natural sources with therapeutic potential.Dr. Anto’s scientific publications have advanced understanding in areas such as natural compound-mediated cancer prevention, signaling pathway modulation, and anti-inflammatory mechanisms of nutraceuticals. Through her research, she continues to bridge the gap between basic biochemistry and applied health sciences, promoting nutraceutical innovation as a cornerstone of preventive and personalized medicine. Her lifelong dedication to scientific inquiry and mentorship underscores her status as one of India’s leading voices in biochemistry and nutraceutical research.

Profile: Google Scholar

Featured Publications

Ruby, A. J., Kuttan, G., Babu, K. D., Rajasekharan, K. N., & Kuttan, R. (1995). Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Letters, 94(1), 79–83.

Anto, R. J., Mukhopadhyay, A., Denning, K., & Aggarwal, B. B. (2002). Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis, 23(1), 143–150.

Anto, R. J., Sukumaran, K., Kuttan, G., Rao, M. N. A., Subbaraju, V., & Kuttan, R. (1995). Anticancer and antioxidant activity of synthetic chalcones and related compounds. Cancer Letters, 97(1), 33–37.

Oommen, S., Anto, R. J., Srinivas, G., & Karunagaran, D. (2004). Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells. European Journal of Pharmacology, 485(1–3), 97–103.*

Anto, R. J., Mukhopadhyay, A., Shishodia, S., Gairola, C. G., & Aggarwal, B. B. (2002). Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: Correlation with induction of cyclooxygenase-2. Carcinogenesis, 23(9), 1511–1518.*

Bava, S. V., Puliappadamba, V. T., Deepti, A., Nair, A., Karunagaran, D., & Anto, R. J. (2005). Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization. Journal of Biological Chemistry, 280(8), 6301–6308.*

Srinivas, G., Anto, R. J., Srinivas, P., Vidhyalakshmi, S., Senan, V. P., & Karunagaran, D. (2003). Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. European Journal of Pharmacology, 473(2–3), 117–125.*

Basant Farag | Drug Discovery and Development | Best Researcher Award

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Dr. Basant Farag | Drug Discovery and Development | Best Researcher Award

Zagazig University Faculty of Science | Egypt

Dr. Basant Farag is a distinguished organic chemist and assistant lecturer at the Department of Chemistry, Faculty of Science, Zagazig University, Egypt, with extensive expertise in the synthesis, biological evaluation, and computational studies of heterocyclic compounds. She completed her Ph.D. in Organic Chemistry at Zagazig University, building on her M.Sc. and B.Sc. degrees in the same field, demonstrating a consistent commitment to advancing chemical sciences. Her academic career encompasses teaching, mentoring students, and conducting cutting-edge research while serving as a teaching assistant and assistant lecturer, preparing lectures, evaluating students, and engaging in independent research projects. Dr. Farag is also an accomplished international reviewer for numerous journals including Chemistry Select, Eurasian Journal of Chemistry, Journal of Molecular Structure, Bioorganic Chemistry, and International Journal of Biological Macromolecules, highlighting her broad expertise and recognition in the global scientific community.Her research portfolio includes pioneering studies in the design and synthesis of biologically active heterocyclic compounds, focusing on pharmacologically relevant molecules with anticancer, antimicrobial, and antitubercular properties. Her notable publications include Synthesis and Molecular Docking of Some Novel 3-Thiazolyl-Coumarins as Inhibitors of VEGFR-2 Kinase, Mechanochemical Synthesis and Molecular Docking Studies of New Azines Bearing Indole as Anticancer Agents, Green Synthesis and Molecular Docking Study of Some New Thiazoles Using Terephthalohydrazide Chitosan Hydrogel as Ecofriendly Biopolymeric Catalyst, Green Route Synthesis and Molecular Docking of Azines Using Cellulose Sulfuric Acid under Microwave Irradiation, Synthesis, Molecular Docking and Anticancer Activity of Some 5-Aryl-5,10-Dihydropyrido[2,3-d:6,5-d′]Dipyrimidine-2,4,6,8-Tetraone Derivatives and Pyrido[2,3-d], Synthesis, Molecular Docking Study, and Biological Evaluation of New Thiadiazole and Thiazole Derivatives Incorporating Isoindoline-1,3-Dione Moiety as Anticancer and Antimicrobial Agents, Green Biocatalyst for Ultrasound-Assisted Thiazole Derivatives: Synthesis, Antibacterial Evaluation, and Docking Analysis, Cyanauric Chloride as a Key Precursor and a Core Component for Three-Armed Triazolopyrimidines: Recent Finding About SARs and Docking Analyses, Chitosan–Sulfonic Acid-Catalyzed Green Synthesis of Naphthalene-Based Azines as Potential Anticancer Agents, Synthesis, Molecular Docking, In Silico Study, and Evaluation of Bis-Thiazole-Based Curcumin Derivatives as Potential Antimicrobial Agents, and Design and Synthesis of Novel Hybrids Incorporating Thiadiazole or Thiazole-Naphthalene: Anticancer Assessment and Molecular Docking Study.

Profile: Google Scholar

Featured Publications

Abolibda, T. Z., Fathalla, M., Farag, B., Zaki, M. E. A., & Gomha, S. M. (n.d.). Synthesis and molecular docking of some novel 3-thiazolyl-coumarins as inhibitors of VEGFR-2 kinase. Molecules.

Ibrahim, M. S., Farag, B., Al-Humaidi, J. Y., Zaki, M. E. A., Fathalla, M., & Gomha, S. M. (n.d.). Mechanochemical synthesis and molecular docking studies of new azines bearing indole as anticancer agents. Molecules.

Gomha, S. M., Riyadh, S. M., Alharbi, R. A. K., Zaki, M. E. A., Abolibda, T. Z., & Farag, B. (n.d.). Green route synthesis and molecular docking of azines using cellulose sulfuric acid under microwave irradiation. Crystals.

Al-Humaidi, J. Y., Gomha, S. M., El-Ghany, N. A. A., Farag, B., Zaki, M. E. A., et al. (n.d.). Green synthesis and molecular docking study of some new thiazoles using terephthalohydrazide chitosan hydrogel as ecofriendly biopolymeric catalyst. Catalysts.

Hussein, A. M., Gomha, S. M., El-Ghany, N. A. A., Zaki, M. E. A., Farag, B., et al. (n.d.). Green biocatalyst for ultrasound-assisted thiazole derivatives: Synthesis, antibacterial evaluation, and docking analysis. ACS Omega.

Mokbel, W. A., Hosny, M. A., Gomha, S. M., Zaki, M. E. A., Farag, B., El Farargy, A. F., et al. (n.d.). Synthesis, molecular docking study, and biological evaluation of new thiadiazole and thiazole derivatives incorporating isoindoline-1,3-dione moiety as anticancer and antimicrobial agents. Results in Chemistry.

Prof Dr.Christophe LEN| Pharmaceutical Chemistry|Excellence in Research

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Prof Dr.Christophe LEN,Pharmaceutical Chemistry ,Excellence in Research

Prof Dr.Christophe LEN, at Chimie ParisTech, France

 Profiles

Scopus

Orcid

🎓Early Academic Pursuits

Professor Dr. Christophe Len’s academic journey began at Université de Picardie Jules Verne in Amiens, France, where he completed his Master of Science (MsC) in Chemistry in 1992. His pursuit of advanced knowledge continued as he earned his PhD in Chemistry from the same institution in 1995. Following his doctoral studies, Dr. Len undertook a post-doctoral fellowship at the University of Hull in England from 1996 to 1997. This period was crucial in shaping his research trajectory and establishing a solid foundation in organic chemistry and catalysis.

🏢Professional Endeavors

Dr. Len’s career is marked by a series of esteemed positions across prominent institutions. He began his academic career as an Assistant Professor at Université de Picardie Jules Verne in 1997. His exceptional contributions led to his rapid ascension in the academic hierarchy, securing a Full Professor position at Université de Poitiers in 2004. Subsequently, he moved to Université de Technologie de Compiègne, where he has served in various capacities, including Full Professor (second class) in 2008 and Full Professor (first class) in 2011. His current role as a Full Professor (Exceptional class) at Chimie ParisTech and Université de Technologie de Compiègne reflects his significant impact and leadership in the field.

🔬Contributions and Research Focus

Dr. Len’s research primarily revolves around innovative approaches in organic chemistry and catalysis. He is renowned for his work in continuous flow chemistry, which enhances the efficiency and sustainability of chemical processes. His expertise extends to applying cutting-edge technologies such as microwave, ultrasound, and ball milling to catalysis, both homogeneous and heterogeneous. His pioneering research on micellar catalysis has further advanced the field, demonstrating his commitment to exploring and developing new methodologies in chemistry.

🏆Accolades and Recognition

Professor Len’s outstanding contributions have earned him numerous accolades and recognition. In 2017, he was honored with the Glycerine Innovation Research Award by the American Oils Chemists’ Society (AOCS). His scholarly excellence has been recognized through various honorary appointments, including Honorary Professor at the University of Hull (2012-2018) and Honorary Professor at Xi’an Jiaotong University, China (2022-2025). He is also a Fellow of the Royal Society of Chemistry (FRSC) and holds honorary life fellowships with the Association of Carbohydrate Chemists and Technologists India (ACCTI) and the Indian Society of Chemists and Biologists (ISCB).

Dr. Len’s editorial roles reflect his influence in the field: he is a member of the editorial boards for several prestigious journals, including Sustainability (Sust. Chem. Eng. Technol.), Material Chemistry (Materials), Biomass Catalysis (Catalysts), and Green Chemistry (Molecules). His service on the management committee for the COST Action FP1306 and the CNRS GDR2053 Synth-Flux further underscores his leadership in advancing green chemistry and flow synthesis technologies.

🌟Impact and Influence

With an impressive h-index of 49 (Scopus) and 51 (Google Scholar), Dr. Len’s work has had a profound impact on the field of chemistry. His research, which includes over 250 peer-reviewed journal articles, 11 patents, and 13 book chapters, has garnered significant attention and citation, reflecting the relevance and quality of his contributions. His extensive participation in conferences and oral communications, as well as his prolific output in posters, showcases his active engagement with the scientific community and his role in disseminating knowledge.

🌍Legacy and Future Contributions

Dr. Len’s legacy is marked by his transformative contributions to organic chemistry and catalysis. His innovative approaches and dedication to advancing chemical processes have set new standards in the field. Looking ahead, his ongoing work in continuous flow chemistry and green chemistry continues to shape the future of sustainable chemical practices. His involvement in global research clusters and editorial boards highlights his commitment to fostering collaboration and driving progress in chemistry.

Professor Dr. Christophe Len’s career exemplifies excellence and innovation in the scientific community. His contributions not only advance fundamental chemistry but also pave the way for future research and applications, solidifying his position as a leading figure in his field.

🎓Publication 

Photocatalytic oxidative desulfurization with Anderson-type polyoxometalates nanoclusters doped carbon nitride

  • Authors   :Zhao, D., Liu, Q., Lü, H., Zhao, J., Len, C.
  • Journal    :Colloids and Surfaces A: Physicochemical and Engineering Aspects
  • Year         : 2024

Glycerol: A green solvent for synthetic chemistry

    • Authors : de Nazaré de Oliveira, A., Melchiorre, M., Farias da Costa, A.A., Santos do Nascimento, L.A., Len, C.
    • Journal   :Sustainable Chemistry and Pharmacy
    • Year       : 2024
Robust synergistic effect between Zn1Mo1 bifunctional TiO2 for efficient ethyl levulinate production from furfural alcohol
  • Authors  :Si, Q., Zhao, D., Yang, Z., Zhao, J., Zhang, H.
  • Journal    :Materials Today Chemistry
  • Year         :  2024
Anderson-type polyoxometalates support on orange peel activated carbon for efficient ethyl levulinate production
  • Authors  : Zhao, D., Zhang, S., Si, Q., Xu, Y., Zhang, H.
  • Journal   :Fuel
  • Year        :   2024

Green and efficient deep eutectic solvent mediated one-step synthesis of Suxamethonium Chloride as Active Pharmaceutical Ingredient

  • Authors  : Sagandira, C.R., Nguyen, R., Liu, Q., Len, C.
  • Journal   :Sustainable Chemistry and Pharmacy
  • Year        : 2024