Prof. Anca Oana Hermenean |Pharmacology |Best Innovation Award

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Prof. Anca Oana Hermenean|Pharmacology |Best Innovation Award|

Prof. Anca Oana Hermenean at Vasile Goldis Western University of Arad, Romania

PROFILE  

scopus

Orcid

Early Academic Pursuits 📚

Prof. Dr. Anca Hermenean began her academic journey at Babes-Bolyai University of Cluj-Napoca, Romania, where she earned her Bachelor’s degree in Biology from 1989 to 1994. This foundational education set the stage for her extensive career in biochemistry and molecular biology. Her academic prowess continued to shine as she pursued a PhD in Biology from 1997 to 2003, focusing on electron microscopy, histopathology, and immunohistochemistry. This period of intense study was marked by rigorous research and a commitment to understanding the microscopic and molecular mechanisms underlying various biological processes.

Professional Endeavors 🏛️

Prof. Hermenean’s professional career is distinguished by her roles in academia and research management. Since 2010, she has served as a Professor at the Faculty of Medicine, Vasile Goldis Western University of Arad (VGWU), where she has made significant contributions to the fields of histology and cell biology. Her expertise in these areas is evidenced by her ongoing research and teaching responsibilities.

In 2016, Prof. Hermenean was appointed Director of the VGWU Doctoral Studies Council, a role in which she has overseen the management and strategic development of doctoral programs in Medicine and Biology. Her leadership extended further in 2017 when she joined the Faculty of Engineering in Foreign Languages at Politehnica University of Bucharest, contributing to the Master Program in Biomaterials for Tissue Engineering. She has taught various courses related to cell and tissue biology, tissue regeneration, and debilitating diseases of tissue.

In 2020, Prof. Hermenean became the Director of the Life Science Institute and Principal Investigator at the Institute of Life Sciences, VGWU. Here, she manages research projects and oversees activities in microscopy labs and the animal facility, reflecting her deep engagement in both research and administration.

Contributions and Research Focus 🔬

Prof. Hermenean’s research contributions are broad and impactful, focusing on several key areas:

  1. Histology and Histopathology: Her work in these fields explores the microscopic structure of tissues and the pathological changes associated with various diseases. This includes significant contributions to understanding how cellular and tissular alterations can affect health.
  2. Phytomedicine: Prof. Hermenean has researched the modulation of signal transduction pathways by phytochemicals, their molecular regulation of anti-inflammatory and anti-fibrotic responses, and their interactions with drugs and chemicals.
  3. Nanobiotechnology: She has been involved in the characterization of bio-interfaces and in vivo biocompatibility studies of nanomaterials. Her work includes assessing the interactions between nanomedicines and biological systems, as well as evaluating structural and ultrastructural toxicological effects.
  4. Regenerative Medicine: Prof. Hermenean’s research also covers tissue repair and regeneration pathways, focusing on molecular signals, growth factors, and the mechanisms of tissue regeneration.

Accolades and Recognition 🏆

Prof. Hermenean’s work has garnered significant recognition within the scientific community. She holds a habilitation in Biology, a postdoctoral qualification that allows her to supervise PhD candidates. Her research has led to numerous publications in peer-reviewed journals, with an H-index of 30 on Scopus and 34 on Google Scholar. Additionally, she has been awarded several patents for her innovations in pharmaceutical compositions and drug delivery systems, underscoring her contributions to practical and applied sciences.

Impact and Influence 🌍

Prof. Hermenean’s influence extends beyond her research and teaching. Her roles in managing research councils and institutes highlight her ability to shape research strategies and educational programs. Her contributions have had a tangible impact on the advancement of biomedical sciences, particularly in the fields of histology, nanobiotechnology, and regenerative medicine.

Her work on phytomedicine and nanobiotechnology is particularly notable for its potential applications in developing new therapeutic approaches and improving existing medical treatments. Her patents and research projects reflect her commitment to translating scientific discoveries into practical solutions.

Legacy and Future Contributions 🔮

Prof. Hermenean’s legacy is marked by her dedication to advancing scientific knowledge and training the next generation of researchers. Her leadership in establishing and managing research infrastructures, such as the animal facility and microscopy labs at VGWU, demonstrates her commitment to fostering a supportive environment for cutting-edge research.

Looking ahead, Prof. Hermenean is poised to continue making significant contributions to her fields of expertise. Her ongoing research and collaborations are expected to yield further advancements in phytomedicine, nanobiotechnology, and regenerative medicine. Her role as a mentor and educator will also play a crucial part in shaping future research and development in these areas.

🎓Publication 

Chrysin-loaded calixarene-cyclodextrin ternary drug delivery system inhibits TGF-β and galectin-1 mediated pathways in diabetic liver

  • Authors   :Balta, C., Herman, H., Ciceu, A., … D’Amico, M., Hermenean, A..
  • Journal    :Biochemical Pharmacology
  • Year         :2024

Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice

  • Authors   :Wang, S., Yu, X., Cheng, L., … Lu, Y., Wu, X..
  • Journal    :Cell Death and Disease
  • Year         :2024

Exploring In Vivo Pulmonary and Splenic Toxicity Profiles of Silicon Quantum Dots in Mice

  • Authors   :Cristian, R.-E., Balta, C., Herman, H., … Dinischiotu, A., Stan, M.S..
  • Journal    :Materials.
  • Year         :2024

Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system

Colloidal and Biological Characterization of Dual Drug-Loaded Smart Micellar Systems

  • Authors   :Herman, H., Rata, D.M., Cadinoiu, A.N., Atanase, L.I., Hermenean, A..
  • Journal    :Polymers
  • Year         :2024

Prof Dr. Elaine Leung|Pharmacology | Best Researcher Award

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Prof Dr. Elaine Leung |Pharmacology|Best Researcher Award|

Prof Dr. Elaine Leung at Department of Biomedical Science, Faculty of Health Science, Macau

PROFILE  

scopus

 

Early Academic Pursuits 🎓

Elaine Lai-Han Leung embarked on her academic journey with a strong foundation in biological sciences, obtaining her BSc in Biology and Biochemistry from The Chinese University of Hong Kong in 2001. Her deep interest in biomedical sciences led her to pursue further studies, earning an MPhil in Biochemistry in 2003, followed by a PhD in Physiology in 2006 from the same institution. Her early academic pursuits laid the groundwork for a career marked by significant contributions to biomedical research, particularly in the fields of cancer biology and traditional Chinese medicine.

Professional Endeavors 🧬

Professor Leung’s professional career has been centered at the University of Macau, where she is a prominent figure in the Department of Biomedical Science, Faculty of Health Science. Over the years, she has established herself as a leading researcher, focusing on the intersection of modern biomedical sciences and traditional Chinese medicine. Her work has involved both academic research and collaborations with industry, where she has taken on numerous consultancy projects, contributing to the development of new therapies and drug discoveries.

Contributions and Research Focus 🔬

Professor Leung’s research is primarily focused on cancer biology, with an emphasis on non-small cell lung cancer (NSCLC). She has been the principal investigator (PI) or co-investigator (Co-I) on numerous research projects, many of which are aimed at understanding the mechanisms of drug resistance and the development of novel therapeutic strategies. Her ongoing research includes studies on KRAS resistance mechanisms, the role of gut microbiota in cancer immunomodulation, and the use of traditional Chinese medicine in treating various forms of cancer.

Some of her key projects include:

  • The relationship between KRAS resistance mechanisms and the immune microenvironment: An ongoing project at the University of Macau aimed at uncovering how KRAS mutations affect immune responses in cancer.
  • High-dimensional single-cell analysis of Sotorasib resistance clinical samples: This research seeks to identify new small molecule inhibitors for treating NSCLC.
  • Investigation of the anti-tumor effect of microbial valeric acid in NSCLC: Completed in 2023, this study explored how microbial byproducts can influence tumor immunity.

Accolades and Recognition 🏆

Professor Leung’s contributions to biomedical science have not gone unnoticed. She has been recognized with numerous awards and honors throughout her career, reflecting her standing in the scientific community. Her work has been cited extensively in leading scientific journals, with her citation index reflecting her influence in the fields of cancer biology and traditional Chinese medicine. Her collaboration with Nobel Laureate Erwin Neher on drug research further underscores her prominence in the field.

Impact and Influence 🌍

The impact of Professor Leung’s work extends beyond academia. Her research has significant implications for the development of new cancer therapies, particularly in the context of drug resistance. By bridging the gap between traditional Chinese medicine and modern biomedical research, she has opened new avenues for treatment that could benefit patients worldwide. Her work on gut microbiota and its role in cancer treatment, for instance, is pioneering in its approach and has the potential to revolutionize how cancer is treated.

Legacy and Future Contributions 🌟

As Professor Leung continues her work at the University of Macau, her legacy is already taking shape. She is helping to mentor the next generation of scientists while pushing the boundaries of what is possible in cancer research. Her ongoing projects, including those funded by significant grants, are expected to yield new insights into cancer biology and treatment. Looking ahead, her contributions will likely continue to influence the field of biomedical sciences, particularly in how traditional Chinese medicine is integrated into modern therapeutic strategies.

Research and Innovations 🧪

Completed/Ongoing Research Projects 📊

Professor Leung has completed numerous research projects, with many others ongoing. Her portfolio includes more than a dozen major projects, ranging from small-scale studies to large, collaborative efforts with industry partners. These projects have attracted significant funding, including:

  • Macao Science and Technology Development Fund (2021/2024): Investigating the combinational treatment effects of ginseng polysaccharides with immunotherapy in lung cancer, with a budget of USD 230,769.
  • Zhuhai UM Science and Technology Institute joint lab projects: Ongoing studies on drug resistance and immune microenvironment interactions in cancer, funded at approximately USD 641,000.

Citation Index 📚

Professor Leung’s work is highly regarded in the scientific community, as reflected by her citation index in databases such as Scopus and the Science Citation Index (SCI). Her research articles have been cited extensively, demonstrating the impact and relevance of her work in advancing biomedical science.

Consultancy/Industry Projects 🤝

Beyond academia, Professor Leung has engaged in several industry-sponsored projects, often serving as a consultant. These projects have allowed her to apply her research in practical settings, contributing to the development of new drugs and therapeutic strategies. Notably, she has collaborated with leading pharmaceutical companies like Janssen Pharmaceuticals, where her work on immunophenotyping in lung cancer patients has been highly influential.

Conclusion 🎯

Professor Elaine Lai-Han Leung’s career is a testament to the power of interdisciplinary research and collaboration. Her contributions to cancer biology, her innovative use of traditional Chinese medicine, and her commitment to bridging the gap between research and industry have made her a pivotal figure in her field. As she continues to explore new frontiers in biomedical science, her legacy will undoubtedly be one of lasting impact, shaping the future of cancer treatment and beyond.

🎓Publication 

Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer

  • Authors   :Zhang, Y.-Z., Lai, H.-L., Huang, C., … Wu, Q.-B., Leung, E.L.-H.
  • Journal    :Phytomedicine
  • Year         :2024

Genome engineering of the human gut microbiome

MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

  • Authors   :Peng, D., Li, J., Li, Y., … Yang, P., Li, G.
  • Journal    :Pharmacological Research.
  • Year         :2024

Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis

 

Prof. Mohamed Abdelzaher|Pharmacology | Best Researcher Award

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Prof. Mohamed Abdelzaher, Pharmacology,Best Researcher Award

Prof. Mohamed Abdelzaher, at Environmental Science and Industrial Development Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University,Egypt

PROFILE

scopus

Early Academic Pursuits 🎓

Mohamed Abuelseoud Abdelzaher embarked on his academic journey at Minia University, where he pursued a Bachelor of Science degree at the Faculty of Science. His passion for environmental science led him to further his studies, culminating in an MSc in Environmental Chemistry from the same institution. His master’s thesis focused on the physico-chemical properties of sewage sludge ash blended cement pastes, a topic that underscored his growing interest in sustainable construction materials. His academic pursuits did not stop there, as he later achieved a Ph.D. in Environmental Science and Industrial Development from the Faculty of Postgraduate Studies for Advanced Sciences at Beni-Suef University in 2019. His doctoral research delved into enhancing the physico-mechanical properties of white cement through the application of nanoparticles, highlighting his commitment to advancing materials science and its environmental implications.

Professional Endeavors 🏢

Dr. Abdelzaher’s professional career began in the industrial sector, where he worked as a Quality Control and Labs Manager at Italcementi Group, Helwan Cement Co., from 2005 to 2017. This role allowed him to gain substantial experience in quality assurance and environmental management within the cement industry. His work in this capacity was instrumental in ensuring that the company adhered to stringent environmental and quality standards, contributing to the sustainability of its operations.

In 2017, Dr. Abdelzaher transitioned into academia, taking on the role of Assistant Professor of Environmental Science and Industrial Development at Beni-Suef University’s Faculty of Postgraduate Studies for Advanced Sciences. In this role, he has been actively involved in teaching, research, and mentorship, guiding the next generation of environmental scientists and engineers. His professional journey reflects a seamless blend of industry experience and academic expertise, making him a respected figure in both fields.

Contributions and Research Focus 🔬

Dr. Abdelzaher’s research is primarily centered on the application of nanomaterials in construction materials and environmental science, with a particular emphasis on waste management. His work on enhancing the properties of white cement using nanoparticles is a testament to his innovative approach to solving environmental and industrial challenges. By integrating cutting-edge nanotechnology into traditional construction materials, he has contributed to the development of more durable and sustainable building solutions.

In addition to his research in construction materials, Dr. Abdelzaher has also made significant contributions to environmental science, particularly in the area of waste management. His work explores how waste materials can be repurposed and utilized in environmentally friendly ways, thereby reducing their impact on the environment and contributing to a circular economy.

Accolades and Recognition 🏅

Throughout his career, Dr. Abdelzaher has received numerous accolades and certifications that attest to his expertise and leadership in his field. He is a certified environmental specialist, having received recognition from the Egyptian Ministry of Environment. He also holds an MBA from Ain Shams University, which complements his scientific expertise with strong business acumen.

Dr. Abdelzaher’s leadership skills have been recognized on an international level, as evidenced by his fellowship from the Science Leadership Program in Africa. This fellowship highlights his role as a thought leader in environmental science, particularly in the context of developing nations. Additionally, he has been awarded fellowships for curriculum development and environmental management, further underscoring his contributions to academia and industry alike.

Impact and Influence 🌍

Dr. Abdelzaher’s work has had a profound impact on both the academic community and the industrial sector. His research on nanomaterials and waste management has influenced the development of more sustainable construction practices, contributing to the global push towards greener building solutions. His teachings and mentorship at Beni-Suef University have inspired countless students to pursue careers in environmental science, ensuring that his influence will be felt for generations to come.

Moreover, his involvement in various professional organizations and his role as a reviewer for environmental journals published by Elsevier demonstrate his commitment to advancing the field of environmental science. Through these roles, he has helped shape the direction of research and development in his field, ensuring that it continues to address the most pressing environmental challenges of our time.

Legacy and Future Contributions 🚀

As Dr. Abdelzaher continues his career, his legacy is one of innovation, leadership, and dedication to sustainability. His work in nanotechnology and waste management has laid the groundwork for future advancements in these fields, and his influence as an educator ensures that his knowledge and expertise will be passed on to the next generation of environmental scientists.

🎓Publication 

Effective impact of nano-plastic-waste incorporated with nanotitina on the physical, mechanical and microstructural properties of white cement pastes composites for progressing towards sustainability

  • Authors   :Abdelzaher, M.A., Farghali, A.A., Hamouda, A.S.
  • Journal    :Scientific Reports
  • Year         :2024

Production, characterization and performance of green geopolymer modified with industrial by-products

    • Authors :Abbas, R., Abdelzaher, M.A., Shehata, N., Tantawy, M.A.
    • Journal   :Scientific Report
    • Year       : 2024

Effect of ginger, chamomile, and green tea extracts on prostate cancer cells

Bacterial biodegradation of oil-contaminated soil for pollutant abatement contributing to achieve sustainable development goals: A comprehensive review

  • Authors  :Aziz, Z.S., Jazza, S.H., Dageem, H.N., … Balboul, B.A., Abdelzaher, M.A.
  • Journal   :Results in Engineering
  • Year        :   2024

Experimental and Theoretical Study of Water Amount on the Rheological Features of Marble Sludge Grout