Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Assist. Prof. Dr. Saikat Chaudhuri at CSIR-Central Leather Research Institute, India.

Assist. Prof. Dr. Saikat Chaudhuri is an accomplished organic chemist specializing in natural product synthesis and green chemistry. 🎓 He earned his Ph.D. from IISER Bhopal, focusing on Clavine alkaloids, and holds degrees from Visva Bharati and Burdwan Universities. 🏅 He is a recipient of the Young Scientist Award (2024) and prestigious UGC fellowships. At CSIR-CLRI, he teaches and mentors students across disciplines, guiding numerous projects and theses. 📚 His innovative research, backed by major grants, has led to impactful publications in synthesis and catalysis. 🧪 His work fuels advancements in affordable pharmaceutical chemistry and sustainable methodologies.

Publication Profile 

Orcid

Education

Assist. Prof. Dr. Saikat Chaudhuri holds an impressive academic background in organic chemistry. He completed his Ph.D. in Organic Chemistry from IISER Bhopal (2013–2017) under the mentorship of Prof. Alakesh Bisai, focusing on the total syntheses of naturally occurring Clavine alkaloids 🧪. Prior to this, he earned his M.Sc. in Organic Chemistry from Visva Bharati University (2010–2012) 📘 and a B.Sc. (Hons.) in Chemistry from Burdwan University (2007–2010) 🔬. His strong academic foundation laid the groundwork for his research excellence and innovative contributions to synthetic organic chemistry and drug development.

Awards

Assist. Prof. Dr. Saikat Chaudhuri has been recognized with several prestigious honors throughout his academic journey. In 2024, he received the Young Scientist Award from the CRS Society, Vidyasagar University 🌟. Earlier, he was awarded the esteemed Dr. D.S. Kothari Postdoctoral Fellowship (2019–2021) by UGC, Government of India 🧪. During his doctoral research, he was a recipient of both Junior Research Fellowship (JRF) and Senior Research Fellowship (SRF) from UGC-NET (2013–2017) 📚. His early promise was evident when he earned the Swami Vivekananda Merit-cum-Means Scholarship (2011–2012) from the Govt. of West Bengal.

Research Focus 

Assist. Prof. Dr. Saikat Chaudhuri is a rising expert in synthetic organic chemistry and medicinal chemistry. His research focuses on the development of novel synthetic methodologies 🧪 for constructing complex heterocycles, such as indoles, benzazepinoindoles, and spiro compounds 🌱. These molecules show promising biological activity, including antibacterial and antifungal properties 💊🦠. He also explores green chemistry approaches, metal-free catalysis, and the total synthesis of natural products 🌍. His work significantly contributes to drug discovery and design, making him a valuable contributor to pharmaceutical research and sustainable chemistry.

Publication Top Notes

  • Synthesis of Dihydro‐benzazepinoindoles via an Oxidative Pictet–Spengler Reaction
  • A New Homogeneous Catalyst for the Synthesis of 3,3′‐Bis(indolyl)methanes: Collective Synthesis of Arundine, Turbomycin B, Arsindoline A, and Tris(1H‐Indol‐3‐yl)methane*
  • A Transition Metal‐Free Strategy for Dihydrobenzazepinoindole via KI‐Mediated Oxidative Pictet–Spengler Reaction
  • Pentafluorophenol‐Catalyzed Metal‐Free Fischer Indole Synthesis: A Novel Approach to Carbazole Derivatives and Desbromoarborescidine A*
  • Water Mediated Chemoselective Synthesis of Novel Spiro Benzoxazinoindoline and Extended Synthesis of Spiro Benzoxazinoindene Derivatives*
  • A Practical and Metal‐Free Approach Towards Synthesis of Spiro‐Benzazepinoindole Derivatives via Pentafluorophenol Catalyzed Pictet‐Spengler Reaction**
  • Efficient, One‐Pot, Green Syntheses of Analogues of 3,4‐Dihydro‐2H Pyrroles as Potential New Antifungal and Antibacterial Agents.
  • A convenient proline catalysed Paal–Knorr synthesis of highly substituted pyrrole: construction of a pyrrolo[2,1-a]isoquinoline scaffold
  • Syntheses of Novel Spirobenzazepinoindole Derivatives via Lewis‐Acid Catalyzed Pictet‐Spengler Cyclization
  • Self-Healable Hydrogels from Vegetable Oil: Preparation, Mechanism, and Applications
  • A Comprehensive Review of Synthetic Approaches Toward Lamellarin D and its Analogous
  • Catalytic Asymmetric Approach to the Naturally Occurring Clavine Alkaloid, (+)-Lysergine
  • Harnessing leather waste in polymer matrix for sustainable smart <scp>shape‐stable</scp> phase change materials
  • Green synthetic approaches for medium ring-sized heterocycles of biological and pharmaceutical interest

José Leite | Drug Discovery and Development | Innovator in Pharmaceutical Research Award

José Leite | Drug Discovery and Development | Innovator in Pharmaceutical Research Award

Dr. José Leite, Universidade de Brasília – UnB, Brazil

Dr. José Roberto Leite is a Brazilian biochemist and molecular biologist with a PhD from the University of Brasília 🇧🇷 and postdoctoral training at EMBRAPA and the University of Porto 🇵🇹. He is an Associate Professor at UnB’s Faculty of Medicine and Visiting Researcher at i3S. 🧪 As co-founder of People&Science, he works on biotechnology, nanobiotech, and bioactive peptides for health and environment 🌿. With 200+ international publications 📚, patents under development 💡, and global collaborations 🌍, he bridges biodiversity and innovation. Dr. Leite also serves as Associate Editor of the Journal of Global Innovation.

Publication Profile

Google Scholar

Education

Dr. José Roberto Leite earned his PhD in Biological Sciences (Biochemistry/Molecular Biology) from the University of Brasília 🇧🇷 and completed postdoctoral training at EMBRAPA and the University of Porto (REQUIMTE) 🇵🇹. He serves as an Associate Professor at UnB’s Faculty of Medicine and is a Visiting Researcher at i3S 🧬. He coordinated graduate programs at UFPI and UnB and founded the Biotec/UFPI research group 🧑‍🔬. As co-founder of People&Science, he leads cutting-edge work in biotechnology, nanobiotechnology, and bioprospecting for health and the environment 🌱. He is also Associate Editor of the Journal of Global Innovation 📘 and promotes international collaboration.

Professional Memberships

Dr. José Roberto Leite is actively engaged in Brazil’s leading scientific communities and holds esteemed memberships in the Brazilian Society for Biochemistry and Molecular Biology 🧪 and the Brazilian Society of Biotechnology 🧬, reflecting his deep commitment to advancing life sciences and innovation. In addition, he plays a key editorial role 📖 in the Journal of Global Innovation (JGI), contributing to the dissemination of cutting-edge research and fostering interdisciplinary collaboration 🌐. His involvement in these professional circles underscores his dedication to scientific excellence, knowledge sharing, and the promotion of impactful biotechnology and molecular biology initiatives across Brazil and beyond.

Research Focus

Dr. José Roberto Leite focuses on cutting-edge research in biotechnology, nanobiotechnology, and natural product-based drug discovery 🌱. His work spans the development of bioactive peptides 🧬, antimicrobial and anticancer compounds 💊, and innovative drug delivery systems 🚀. He explores biodiversity to identify novel molecules from amphibians 🐸, plants 🌿, and marine life 🌊 for therapeutic and diagnostic applications. Dr. Leite also contributes to the advancement of biosensors, nutraceuticals, and functional biomaterials. His interdisciplinary research bridges biochemistry, molecular biology, and pharmacology, driving translational science for global health and environmental impact.

Publication Top Notes

Dermaseptins from Phyllomedusa oreades andPhyllomedusa distincta: ANTI-TRYPANOSOMA CRUZI ACTIVITY WITHOUT CYTOTOXICITY TO MAMMALIAN CELLS

Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus

Transtornos de ansiedade e exercício físico

Identification of a cowpea γ‐thionin with bactericidal activity

Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens

Medical students, spirituality and religiosity-results from the multicenter study SBRAME

Anti-inflammatory and Antinociceptive Activity of Epiisopiloturine, an Imidazole Alkaloid Isolated from Pilocarpus microphyllus

Novel dermaseptins from Phyllomedusa hypochondrialis (Amphibia)

Development and antibacterial activity of cashew gum-based silver nanoparticles

Antinociceptive activity of the monoterpene α-phellandrene in rodents: possible mechanisms of action

The NMR-derived solution structure of a new cationic antimicrobial peptide from the skin secretion of the anuran Hyla punctata

Antidiarrheal activity of cashew GUM, a complex heteropolysaccharide extracted from exudate of Anacardium occidentale L. in rodents

Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

Dr Hui Xiao,regeneron,United States

Dr. Hui Xiao 🧪🔬 is a distinguished scientist specializing in biochemistry, structural biology, and mass spectrometry. With a strong focus on microtubule dynamics, protein interactions, and drug mechanisms, he has made significant contributions to understanding cellular processes. As a co-first author and lead researcher, his work has been published in esteemed journals like J. Mol. Biol., Biochemistry, and J. Biol. Chem.. His expertise spans hydrogen-deuterium exchange, proteomics, and molecular stabilization studies. Dr. Xiao’s research has advanced drug discovery, particularly in cancer therapeutics and protein biochemistry. 📚🔍 His innovative approaches continue to impact biomedical sciences globally. 🌍✨

Publication Profile

Scopus

Education

Dr. Hui Xiao 🎓 holds a Ph.D. in Analytical Chemistry from the University of Massachusetts, Amherst (2005) and a degree in Applied Chemistry from Peking University, China (1992). Currently serving as an Associate Director at Regeneron Pharmaceuticals 🏢, he specializes in protein characterization using mass spectrometry. With over a decade at Regeneron, he has progressed through roles as a Senior Staff Scientist and Staff Scientist. Previously, he held academic positions at Albert Einstein College of Medicine 🧬, advancing from Instructor to Research Associate Professor. His expertise spans analytical chemistry, protein analysis, and therapeutic protein research, making significant contributions to biomedical science. 🔬

Professional Impact

Dr. Hui Xiao 🎓 is a distinguished scientist with over 20 years of experience in academia and the biotechnology industry. Currently, he serves as an Associate Director of Analytical Chemistry at Regeneron Pharmaceuticals 🏢, a leading biotech company. His expertise lies in mass spectrometry applications for protein characterization 🔬, contributing to advancements in therapeutic development. Before joining Regeneron, Dr. Xiao held esteemed faculty positions at Albert Einstein College of Medicine 🧬, progressing from Instructor to Research Associate Professor. His extensive research and leadership have played a crucial role in bridging analytical chemistry with biopharmaceutical innovation, impacting drug discovery and development. 🚀

Scientific Contributions

Dr. Hui Xiao 🎓 is a leading expert in protein-ligand interactions, structural proteomics, and therapeutic protein analysis 🔬. His pioneering work includes the application of hydrogen-deuterium exchange mass spectrometry (HDX-MS) for epitope mapping 🧩 and microtubule stabilization research. With a deep focus on drug characterization and regulatory sciences, his contributions have significantly advanced biopharmaceutical development 💊. His expertise in mass spectrometry-driven protein analysis has helped enhance the understanding of molecular mechanisms, improving therapeutic strategies. Through innovation and research, Dr. Xiao continues to play a vital role in shaping the future of biopharmaceutical science and drug discovery. 🚀

Potential Considerations

Dr. Hui Xiao 🎓 is a renowned expert in analytical and protein chemistry, with groundbreaking work in epitope mapping and protein characterization 🔬. While his contributions significantly impact drug development, the Pharmaceutical Innovation Achievement Award 🏆 may prioritize direct advancements in drug discovery and novel pharmaceutical interventions 💊. His research has important regulatory and therapeutic implications, but highlighting specific drug innovations or regulatory breakthroughs he has led would further strengthen his case. By showcasing his role in pioneering pharmaceutical advancements, Dr. Xiao’s influence in shaping modern biopharmaceutical science can be fully recognized and appreciated. 🚀

Research Focus

Dr. Hui Xiao’s research primarily focuses on analytical chemistry 🧪, particularly in the quantitative analysis of biomolecules 🧬 using advanced mass spectrometry techniques ⚖️. His work involves CRISPR sgRNA modification analysis 🧬🔬 and the development of LC-MS-based assays for biological therapeutics 💊. He specializes in phosphorothioate isomer detection 🔄 and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS) 📊 for precise biomolecular quantification. His contributions are crucial in drug discovery 🏥, gene editing 🧬, and biopharmaceutical development 💉. His expertise bridges biotechnology 🔬 and analytical methodologies 📈, advancing innovations in therapeutic monitoring and molecular diagnostics 🏥.

Publication Top Notes

Quantitative Analysis of Phosphorothioate Isomers in CRISPR sgRNA at Single-Residue Resolution Using Endonuclease Digestion Coupled with Liquid Chromatography Cyclic Ion Mobility Mass Spectrometry (LC/cIMS)

Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum