Mr. Karanvir Singh | Medicinal Chemistry | India
Guru Nanak Dev University | India
Mr. Karanvir Singh is a dynamic and highly skilled researcher in the field of pharmaceutical chemistry, currently pursuing his Doctorate of Philosophy at the Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India. His ongoing doctoral research, under the supervision of Prof. Dr. Preet Mohinder Singh Bedi, focuses on the design and synthesis of 1,2,4-triazine hybrids with Nipecotic acid for anticonvulsant activity, emphasizing computational modeling, synthesis, and biological evaluation of novel anticonvulsant agents. He holds a Master’s degree in Pharmacy (Pharmaceutical Chemistry) from ISF College of Pharmacy, Moga, Punjab, where he completed a thesis on the design and synthesis of 1,2,4-triazine derivatives for anticonvulsant activity under the guidance of Dr. Vikramdeep Monga and Dr. Bhupinder Kumar. His strong academic foundation was built upon a Bachelor of Pharmacy from the Laureate Institute of Pharmacy, Himachal Pradesh.With a blend of academic excellence and industrial exposure, Mr. Singh has worked as an Assistant QA Chemist at United Biotech Pvt. Ltd., where he gained extensive experience in pharmaceutical quality assurance. His scientific expertise spans molecular docking, fragment-based drug design, pharmacophore modeling, molecular dynamics simulations, organic synthesis, compound purification, and structural elucidation using analytical tools such as NMR, FT-IR, HPLC, and Mass spectrometry.Mr. Singh has made significant contributions to the scientific community, authoring multiple research and review articles in reputed journals. His notable publications include Design, Synthesis, and Biological Evaluation of Triazole-Linked Lignan–Monoterpenoid-Based Hybrid Molecules as Xanthine Oxidase Inhibitors with Potent In Vivo Efficacy; Design, Synthesis, and Multi-Target Biological Evaluation of 1,2,3-Triazole Linked Indole–Thiazolidinedione Hybrids as Potent α-Glucosidase, α-Amylase, and DPP-4 Inhibitors with Antioxidant Potential; Design, Synthesis, Antibacterial Evaluation, and Molecular Modelling Studies of 1,2,3-Triazole-Linked Coumarin–Vanillin Hybrids as Potential DNA Gyrase and Topoisomerase IV Inhibitors; and Development of Coumarin-Inspired Bifunctional Hybrids as a New Class of Anti-Alzheimer’s Agents with Potent In Vivo Efficacy. His review works, such as Exploring Norfloxacin Analogs in Combating Antimicrobial Resistance: Design, Mechanistic Insights, and Structure–Activity Relationship and Incredible Indolinedione Derivatives Nucleus in the Development of Anti-Diabetic Drugs: Exploring the Mechanistic Studies, Design, and Structure–Activity Relationship, further demonstrate his broad research vision and scientific depth.
Profile: Google Scholar
Featured Publications
Singh, K., Pal, R., Khan, S. A., Kumar, B., & Akhtar, M. J. Insights into the structure–activity relationship of nitrogen-containing heterocyclics for the development of antidepressant compounds: An updated review. Journal of Molecular Structure.
Singh, A., Malhotra, D., Singh, K., Chadha, R., & Bedi, P. M. S. Thiazole derivatives in medicinal chemistry: Recent advancements in synthetic strategies, structure–activity relationship, and pharmacological outcomes. Journal of Molecular Structure.
Singh, A., Singh, K., Sharma, A., Kaur, K., Kaur, K., Chadha, R., & Bedi, P. M. S. Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight. Journal of Molecular Structure.
Pal, R., Singh, K., Khan, S. A., Chawla, P., Kumar, B., & Akhtar, M. J. Reactive metabolites of the anticonvulsant drugs and approaches to minimize the adverse drug reaction. European Journal of Medicinal Chemistry.
Singh, A., Singh, K., Sharma, A., Kaur, K., Chadha, R., & Bedi, P. M. S. Recent advances in antifungal drug development targeting lanosterol 14α-demethylase (CYP51): A comprehensive review with structural and molecular insights. Chemical Biology & Drug Design.