Fenghua Wu | Oncology Pharmaceuticals | Best Researcher Award

Fenghua Wu | Oncology Pharmaceuticals | Best Researcher Award

Mrs. Fenghua Wu at Hubei university of chinese medcine, China.

Mrs. Fenghua Wu is a distinguished researcher and educator with a doctoral degree from Tongji Medical College, Huazhong University of Science and Technology 🎓. She specializes in physiology and oncology, focusing on the tumor microenvironment and tumor immunology 🔬. Her groundbreaking research explores the regulatory mechanisms of natural and traditional Chinese medicines in cancer treatment 🌿. As a principal investigator for the National Natural Science Foundation of China, she has published extensively in SCI-indexed journals 📚. Honored as a “Teaching Expert” and COVID-19 frontline contributor 🏅, she also serves as a Guest Editor for Frontiers in Immunology.

Publication Profile 

Scopus

Education

Mrs. Fenghua Wu earned her doctoral degree from Tongji Medical College, Huazhong University of Science and Technology 🏥. She currently teaches physiology and is actively engaged in oncology research 🔬 at her institution. Her work focuses on exploring cancer biology and its treatment mechanisms. As a leading scientist, she has served as the principal investigator for prestigious projects funded by the National Natural Science Foundation of China 🇨🇳. Her academic dedication and scientific contributions reflect her commitment to advancing knowledge in the field of cancer research and education.

Professional Memberships

Mrs. Fenghua Wu is a proud member of the Chinese Anti-Cancer Association (CACA) 🧬, a prestigious national organization committed to advancing cancer research, treatment, and public health awareness in China 🇨🇳. Her affiliation with CACA underscores her dedication to the oncology field and her active participation in collaborative efforts aimed at combating cancer through scientific innovation and knowledge exchange 🔬. As part of this professional body, she stays connected with leading experts, contributes to cancer-related initiatives, and continuously enhances her expertise to benefit patients and students alike.

Research Focus 

Mrs. Fenghua Wu’s research focus lies at the intersection of tumor immunology, traditional Chinese medicine, and molecular oncology 🧬. She explores how natural compounds—such as dihydroartemisinin and capsaicin—can modulate immune responses and inhibit cancer progression, particularly in breast cancer and tongue squamous cell carcinoma (TSCC) 🎯. Her studies often center on critical pathways like TNF-α, PI3K/AKT/mTOR, and TGF-β1, highlighting her commitment to advancing immunotherapy and targeted therapies 🧪. Her category of research can be broadly classified under Cancer Pharmacology, Immuno-Oncology, and Natural Product-Based Therapeutics.

Publication Top Notes

  • Dihydroartemisinin restrains angiogenesis through the TNF-α pathway to enhance the efficacy of anti-PD-1 immunotherapy in breast cancer
  • Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway

Dr.Long Pang |Oncology Pharmaceuticals| Best Researcher Award-1332

Dr.Long Pang|Oncology Pharmaceuticals |Best Researcher Award|

Dr.Long Pang at Xi’an Medical University, China

PROFILE  

scopus

Early Academic Pursuits 📚

Long Pang was born in Gansu, China, where he developed an early passion for science and innovation. His academic journey began with a focus on veterinary science, where he pursued a Master of Science (M.S.) degree at Northwest Agricultural and Forestry University in Yangling, Shaanxi, China. Completing his M.S. in July 2012, Pang demonstrated an exceptional commitment to his studies and research in veterinary science, laying the groundwork for his future endeavors in animal biotechnology. In August 2012, he advanced his academic career by enrolling in a Ph.D. program at the same university. During his Ph.D. studies, he specialized in Animal Biotechnology, a field that encompasses the use of biotechnological tools for the improvement of animal health and productivity. He completed his Ph.D. in July 2016, marking the beginning of a promising career in biomedical research.

Professional Endeavors 🏢

After earning his Ph.D., Long Pang joined Xi’an Medical University as an Associate Professor in the School of Basic Medical Science. His professional career is distinguished by his innovative research in the areas of microfluidics and single-cell analysis. At Xi’an Medical University, Pang quickly established himself as a leading researcher, focusing on the development of microfluidic chips and their applications in single-cell analysis and organ-on-a-chip technology. His work has been instrumental in advancing the understanding of cellular mechanics and tumor microenvironments, contributing significantly to the fields of biomedical engineering and cancer research.

Contributions and Research Focus 🔬

Long Pang’s research primarily revolves around microfluidics-based single-cell analysis and organ-on-a-chip technologies. His work has led to the development of innovative microfluidic devices that allow for the manipulation and analysis of single cells in a highly controlled environment. These devices have broad applications in cancer research, particularly in studying tumor microenvironments and the behavior of cancer stem cells. One of his significant contributions includes the development of a microfluidic chip for glioma stem cell sorting and single-cell-derived tumor sphere assays. This research has provided valuable insights into the formation of tumor spheres and the role of the tumor microenvironment in cancer progression.

Pang has also been involved in projects aimed at integrating microfluidic platforms with other technologies to enhance the precision and efficiency of single-cell analysis. His research has been supported by several prestigious grants, including those from the National Science Foundation of China and the Fundamental Research Foundation of Xi’an Medical University. Notably, he has led projects such as the study of heterotypic single-cell-derived tumor-sphere formation using an integrated microfluidics platform, which has garnered significant attention and funding.

Accolades and Recognition 🏆

Long Pang’s contributions to the field of biomedical research have been widely recognized. His work has resulted in over 21 publications in high-impact journals, including TRAC-Trends in Analytical Chemistry, Analytical Chemistry, and Sensors & Actuators B: Chemical. He has also authored a chapter in the Handbook of Single-Cell Technologies, published by Springer, highlighting his expertise in digital microfluidics for single-cell manipulation and analysis. In addition to his publications, Pang has been granted two Chinese patents related to his innovations in microfluidic technology, further establishing his reputation as a leading researcher in his field.

Pang’s achievements have also been acknowledged through various editorial appointments. He has served as a Youth Editorial Board Member of Glioma and the E-Journal of Translational Medicine, where he has contributed to the advancement of research dissemination and knowledge sharing in the scientific community. His contributions to the academic community extend beyond research, as he is an active member of several professional organizations, including the Shaanxi Pharmacology Association, the Chinese Society of Micro-Nano Technology (CSMNT), and the Chinese Chemistry Society (CCS).

Impact and Influence 🌍

The impact of Long Pang’s research extends beyond academia. His work on microfluidic devices has the potential to revolutionize the way single-cell analysis is conducted, offering new tools for researchers and clinicians in the diagnosis and treatment of diseases, particularly cancer. His contributions to the development of organ-on-a-chip technology are also significant, providing a platform for more accurate and efficient drug testing, which could lead to more effective treatments for various diseases.

Pang’s research has influenced a new generation of scientists and engineers, inspiring them to explore the possibilities of microfluidics and its applications in biomedical research. His collaborations with other leading researchers and institutions, both in China and internationally, have further expanded the reach of his work, fostering innovation and knowledge exchange in the global scientific community.

Legacy and Future Contributions 🚀

Long Pang’s legacy in the field of biomedical research is characterized by his innovative approach to solving complex problems in cell biology and medicine. His contributions to the development of microfluidic technology and single-cell analysis tools have set new standards in the field, paving the way for future research and innovation. As he continues his work at Xi’an Medical University, Pang remains committed to advancing the frontiers of biomedical engineering, with a focus on developing new technologies that can improve human health and well-being.

Looking to the future, Long Pang’s ongoing research projects, such as the construction of a 3D microenvironment for single-cell level tumor cells, promise to yield further breakthroughs in our understanding of cancer and other diseases. His work is likely to continue to influence the field for years to come, as he mentors the next generation of researchers and contributes to the global effort to improve healthcare through technological innovation.

🎓Publication 

Tumor microenvironment-derived exosomes-assisted single-cell-derived tumor-sphere formation and drug-resistance by a microfluidic system

Construction of multiple concentration gradients for single-cell level drug screening

Droplets microfluidics platform—A tool for single cell research

Microfluidics-Based Single-Cell Research for Intercellular Interaction

Digital Microfluidics for Single Cell Manipulation and Analysis

  • Authors   :Pang, L., Ding, J., Fan, S.-K.
  • Journal    :Handbook of Single-Cell Technologies
  • Year         :2021