Jean Noël Nyemb | Medicinal Chemistry | Editorial Board Member

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Assist. Prof. Dr. Jean Noël Nyemb | Medicinal Chemistry | Editorial Board Member

The University of Maroua | Cameroon

Assist. Prof. Dr. Jean Noël Nyemb is a distinguished Cameroonian scholar in Organic Chemistry, widely recognized for his contributions to natural products chemistry, medicinal chemistry, and applied chemical sciences. He serves as a Senior Lecturer in the Department of Refining and Petrochemistry at the National Advanced School of Mines and Petroleum Industries, University of Maroua, where he plays a leading role in teaching, research, postgraduate supervision, and curriculum development. Over the course of his academic journey, he has held several positions across respected higher education institutions, including the University of Maroua, the University of Ngaoundere, and the Higher Institute of Science and Technology of Yaounde. His progressive career includes roles as Instructor, Lecturer, Part-time Lecturer, Research Fellow, and ultimately Senior Lecturer, reflecting a consistent record of academic excellence, professional growth, and dedication to scientific advancement.Dr. Nyemb earned his Ph.D. in Organic Chemistry with the highest distinction, specializing in Natural Products Chemistry, following a strong academic foundation that includes graduate and undergraduate degrees in Organic and Applied Chemistry. His scientific expertise covers the isolation, characterization, and structural elucidation of secondary metabolites, the synthesis and semi-synthesis of biologically active compounds, and the evaluation of their pharmacological potential, including antimicrobial, antioxidant, enzyme-inhibitory, and chemotaxonomic relevance. His research further integrates molecular docking, computational drug design, pharmacokinetics, toxicology, enzymology, and biochemistry, illustrating his multidisciplinary approach to discovering bioactive molecules with therapeutic value.With more than forty publications, an impressive cumulative impact factor, and numerous articles as principal or co-author, Dr. Nyemb has established himself as a productive scientist in his field. His works span areas such as phytochemical profiling, medicinal plant research, natural compound synthesis, and biological activity evaluation. His publications are well-cited globally, and his h-index reflects strong scholarly influence. Dr. Nyemb is also actively involved in ongoing research projects focusing on bioactive compounds from Vernonia species and members of the Zingiberaceae family, highlighting his interest in medicinal plants and ethnopharmacological resources.

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Featured Publications

Ali Darehkordi | Medicinal Chemistry | Research Excellence Award

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Prof. Dr. Ali Darehkordi | Medicinal Chemistry | Research Excellence Award

Vali-e-Asr University of Rafsanjan | Iran

Prof. Dr. Ali Darehkordi is a distinguished Iranian chemist whose academic and professional career reflects deep expertise in organic synthesis, catalysis, drug modification, heterocyclic chemistry, and the design of biologically active fluorinated compounds. He holds a Ph.D., M.Sc., and B.Sc. in Organic Chemistry and Chemistry from leading Iranian universities, with a strong foundational background in natural sciences. Beginning his academic journey as an instructor in the Faculty of Science at Vali-e-Asr University of Rafsanjan, he steadily advanced through key academic ranks, serving as Assistant Professor, Associate Professor, and ultimately Professor of Organic Chemistry. Throughout his career, he has also held several important administrative and leadership roles, including Deputy of the Faculty of Science, Director of the Department of Chemistry, and repeated appointments as Head of the Faculty of Basic Sciences, where he contributed to academic development, departmental management, curriculum enhancement, and research advancement.Prof. Darehkordi’s research accomplishments have earned him multiple awards, including several Excellent Researcher Awards at the faculty, departmental, and university levels, recognizing his contributions to both scientific research and industrial collaboration. His scientific interests span a wide range of advanced topics, such as the design, synthesis, and biological evaluation of trifluoromethylated heterocyclic compounds with anticancer potential, catalysis reactions, drug modification using trifluoroacetimidoyl chlorides, organic synthesis pathways, carbohydrate reaction mechanisms, and herbal medicine applications. His laboratory expertise includes hands-on proficiency with NMR, FT-IR, microwave reactors, ultrasound systems, and polarimetry, supporting his ability to conduct complex chemical characterizations and innovative synthesis techniques.As an active researcher with extensive contributions to international journals, Prof. Darehkordi has authored impactful publications, including A novel bistrifluoromethylated compound as highly efficient nematicide against root-knot nematode on pistachio and docking study, Antitumor activities of a novel fluorinated small molecule (A1) in CT26 colorectal cancer cells: molecular docking and in vitro studies, and A facile and catalyst-free microwave-promoted method for the synthesis of 3-trifluoromethyl 1,2,4-triazole-5-thiones. These publications highlight his innovative chemical synthesis approaches, application-driven research mindset, and strong integration of computational docking, biological testing, and modern reaction methodologies. Prof. Dr. Ali Darehkordi continues to stand as a leading scientist in organic and medicinal chemistry, contributing meaningfully to drug discovery, reaction design, and fluorinated molecule development.

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Featured Publications

Moghadam, M. R., Jahromi, S. M. P., & Darehkordi, A. (2016). Simultaneous spectrophotometric determination of copper, cobalt, nickel and iron in foodstuffs and vegetables with a new bis thiosemicarbazone ligand using chemometric approaches. Food Chemistry, 192, 424–431.

Darehkordi, A., Saidi, K., & Islami, M. R. (2007). Preparation of heterocyclic compounds by reaction of dimethyl and diethyl acetylene dicarboxylate (DMAD, DEAD) with thiosemicarbazone derivatives. Arkivoc, 1, 180–188.

Darehkordi, A., Rahmani, F., & Hashemi, V. (2013). Synthesis of new trifluoromethylated indole derivatives. Tetrahedron Letters, 54(35), 4689–4692.

Funt, L. D., Tomashenko, O. A., Novikov, M. S., & Khlebnikov, A. F. (2018). An azirine strategy for the synthesis of alkyl 4-amino-5-(trifluoromethyl)-1H-pyrrole-2-carboxylates. Synthesis, 50(24), 4809–4822.

Karimabad, M. N., Mahmoodi, M., Jafarzadeh, A., Darehkordi, A., Hajizadeh, M. R., et al. (2017). The novel Indole-3-formaldehyde (2-AITFEI-3-F) is involved in processes of apoptosis induction? Life Sciences, 181, 31–44.

Karimabad, M. N., Mahmoodi, M., Jafarzadeh, A., Darehkordi, A., Hajizadeh, M. R., et al. (2017). Evaluating of OCT-4 and NANOG was differentially regulated by a new derivative indole in leukemia cell line. Immunology Letters, 190, 7–14.

Karanvir Singh | Medicinal Chemistry | Best Researcher Award

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Mr. Karanvir Singh | Medicinal Chemistry | India

Guru Nanak Dev University | India

Mr. Karanvir Singh is a dynamic and highly skilled researcher in the field of pharmaceutical chemistry, currently pursuing his Doctorate of Philosophy at the Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India. His ongoing doctoral research, under the supervision of Prof. Dr. Preet Mohinder Singh Bedi, focuses on the design and synthesis of 1,2,4-triazine hybrids with Nipecotic acid for anticonvulsant activity, emphasizing computational modeling, synthesis, and biological evaluation of novel anticonvulsant agents. He holds a Master’s degree in Pharmacy (Pharmaceutical Chemistry) from ISF College of Pharmacy, Moga, Punjab, where he completed a thesis on the design and synthesis of 1,2,4-triazine derivatives for anticonvulsant activity under the guidance of Dr. Vikramdeep Monga and Dr. Bhupinder Kumar. His strong academic foundation was built upon a Bachelor of Pharmacy from the Laureate Institute of Pharmacy, Himachal Pradesh.With a blend of academic excellence and industrial exposure, Mr. Singh has worked as an Assistant QA Chemist at United Biotech Pvt. Ltd., where he gained extensive experience in pharmaceutical quality assurance. His scientific expertise spans molecular docking, fragment-based drug design, pharmacophore modeling, molecular dynamics simulations, organic synthesis, compound purification, and structural elucidation using analytical tools such as NMR, FT-IR, HPLC, and Mass spectrometry.Mr. Singh has made significant contributions to the scientific community, authoring multiple research and review articles in reputed journals. His notable publications include Design, Synthesis, and Biological Evaluation of Triazole-Linked Lignan–Monoterpenoid-Based Hybrid Molecules as Xanthine Oxidase Inhibitors with Potent In Vivo Efficacy; Design, Synthesis, and Multi-Target Biological Evaluation of 1,2,3-Triazole Linked Indole–Thiazolidinedione Hybrids as Potent α-Glucosidase, α-Amylase, and DPP-4 Inhibitors with Antioxidant Potential; Design, Synthesis, Antibacterial Evaluation, and Molecular Modelling Studies of 1,2,3-Triazole-Linked Coumarin–Vanillin Hybrids as Potential DNA Gyrase and Topoisomerase IV Inhibitors; and Development of Coumarin-Inspired Bifunctional Hybrids as a New Class of Anti-Alzheimer’s Agents with Potent In Vivo Efficacy. His review works, such as Exploring Norfloxacin Analogs in Combating Antimicrobial Resistance: Design, Mechanistic Insights, and Structure–Activity Relationship and Incredible Indolinedione Derivatives Nucleus in the Development of Anti-Diabetic Drugs: Exploring the Mechanistic Studies, Design, and Structure–Activity Relationship, further demonstrate his broad research vision and scientific depth.

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Featured Publications

Singh, K., Pal, R., Khan, S. A., Kumar, B., & Akhtar, M. J. Insights into the structure–activity relationship of nitrogen-containing heterocyclics for the development of antidepressant compounds: An updated review. Journal of Molecular Structure.

Singh, A., Malhotra, D., Singh, K., Chadha, R., & Bedi, P. M. S. Thiazole derivatives in medicinal chemistry: Recent advancements in synthetic strategies, structure–activity relationship, and pharmacological outcomes. Journal of Molecular Structure.

Singh, A., Singh, K., Sharma, A., Kaur, K., Kaur, K., Chadha, R., & Bedi, P. M. S. Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight. Journal of Molecular Structure.

Pal, R., Singh, K., Khan, S. A., Chawla, P., Kumar, B., & Akhtar, M. J. Reactive metabolites of the anticonvulsant drugs and approaches to minimize the adverse drug reaction. European Journal of Medicinal Chemistry.

Singh, A., Singh, K., Sharma, A., Kaur, K., Chadha, R., & Bedi, P. M. S. Recent advances in antifungal drug development targeting lanosterol 14α-demethylase (CYP51): A comprehensive review with structural and molecular insights. Chemical Biology & Drug Design.

Wai Har Ng | Drug Discovery and Development | Best Researcher Award

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Ms. Wai Har Ng | Drug Discovery and Development | Best Researcher Award

Senior Research Associate at National Cancer Centre Singapore | Singapore

Ms. Wai Har Ng is a Senior Research Associate at the National Cancer Centre Singapore with over two decades of experience in cancer biology and translational research. His scientific journey spans genetic engineering, molecular oncology, and personalized therapeutics, with a strong focus on hepatocellular carcinoma, peritoneal carcinomatosis, and colorectal cancer. A dynamic contributor to national research consortiums, Ng WH has authored numerous high-impact publications and excels in molecular, cellular, and in vivo experimental platforms. Known for his collaborative spirit, he plays a pivotal role in mentoring, protocol development, and driving clinical translation in cancer therapy through precision medicine and molecular marker discovery.

Publication Profile 

Scopus

Education

Ms. Wai Har Ng obtained a Master of Science in Genetic Engineering from University Putra Malaysia (2005), where his dissertation focused on gene expression profiling of oil palm root systems using EST and microarray technology. He earned his Bachelor of Science in Biotechnology (2000) from the same university, working on Arabidopsis root transformation. His foundational education was completed at Chong Hwa Independent High School, Kuala Lumpur, from 1990–2000, with certifications including STPM, SPM, and SRP. His early academic training at SRJK (C) Tsun Jin laid the groundwork for a career defined by scientific curiosity, discipline, and innovation in molecular biosciences.

Experience 

Ms. Wai Har Ng currently serves as a Senior Research Associate at the National Cancer Centre Singapore (2017–present), where he spearheads research on molecular therapeutics and biomarker discovery. He previously worked as a Research Officer and Research Associate at the same institute (2004–2017), contributing to groundbreaking oncology studies. Earlier, he served at the Malaysian Agricultural Research & Development Institute (MARDI) from 2003–2004. His academic skillset spans molecular biology, proteomics, imaging, animal studies, and lab management. Proficient in BSL2 safety, grant collaboration, and multidisciplinary research, he plays a key role in mentoring, lab operations, and translational biomedical research.

Awards 

While specific awards were not listed, Ng WH’s achievements are evident through his prolific publication record in high-impact journals, participation in national research consortia like the Singapore Peritoneal Oncology Study (SPOS) and Singapore Gastric Cancer Consortium (SGCC), and recognition as a core contributor to precision oncology research. His co-authorship on influential studies in Scientific Reports, Cell Reports Medicine, and International Journal of Molecular Sciences demonstrates academic recognition and leadership. His technical versatility and mentorship roles further highlight his contribution to national cancer research excellence. If formal awards were earned, these would further bolster his already commendable profile.

Research Focus 

Ng WH focuses on translational cancer research with emphasis on hepatocellular carcinoma, colorectal cancer, peritoneal carcinomatosis, and liposarcoma. His work integrates drug synergy, molecular profiling, biomarker discovery, and machine learning to optimize personalized cancer therapies. He is proficient in CRISPR, ddPCR, organoid modeling, xenografts, and immunofluorescence microscopy. A key area includes developing predictive molecular signatures for chemotherapy response and leveraging advanced imaging to study tumor behavior. With over 13 peer-reviewed publications, Ng WH bridges basic science and clinical application, contributing to a future where cancer treatment is personalized, precise, and highly effective.

Publication Top Notes

Title: Vinorelbine Improves the Efficacy of Sorafenib against Hepatocellular Carcinoma: A Promising Therapeutic Approach
Journal: International Journal of Molecular Sciences
Year: 2024
Citations: 5

Title: Everolimus Acts in Synergy with Vinorelbine to Suppress the Growth of Hepatocellular Carcinoma
Journal: International Journal of Molecular Sciences
Year: 2024
Citations: 4

Conclusion

Ms. Wai Har Ng is a highly competent and experienced researcher whose scientific contributions have advanced the field of cancer biology and therapeutics. Her technical mastery, consistent publication output, and collaborative involvement with national research consortia highlight her as a valuable asset to the research community. With increased visibility through leadership roles in publications and funding acquisition, she would stand out even more prominently. She is a strong and deserving candidate for the Best Researcher Award, given her sustained excellence, innovation, and impact in translational cancer research.