Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

Dr Hui Xiao,regeneron,United States

Dr. Hui Xiao 🧪🔬 is a distinguished scientist specializing in biochemistry, structural biology, and mass spectrometry. With a strong focus on microtubule dynamics, protein interactions, and drug mechanisms, he has made significant contributions to understanding cellular processes. As a co-first author and lead researcher, his work has been published in esteemed journals like J. Mol. Biol., Biochemistry, and J. Biol. Chem.. His expertise spans hydrogen-deuterium exchange, proteomics, and molecular stabilization studies. Dr. Xiao’s research has advanced drug discovery, particularly in cancer therapeutics and protein biochemistry. 📚🔍 His innovative approaches continue to impact biomedical sciences globally. 🌍✨

Publication Profile

Scopus

Education

Dr. Hui Xiao 🎓 holds a Ph.D. in Analytical Chemistry from the University of Massachusetts, Amherst (2005) and a degree in Applied Chemistry from Peking University, China (1992). Currently serving as an Associate Director at Regeneron Pharmaceuticals 🏢, he specializes in protein characterization using mass spectrometry. With over a decade at Regeneron, he has progressed through roles as a Senior Staff Scientist and Staff Scientist. Previously, he held academic positions at Albert Einstein College of Medicine 🧬, advancing from Instructor to Research Associate Professor. His expertise spans analytical chemistry, protein analysis, and therapeutic protein research, making significant contributions to biomedical science. 🔬

Professional Impact

Dr. Hui Xiao 🎓 is a distinguished scientist with over 20 years of experience in academia and the biotechnology industry. Currently, he serves as an Associate Director of Analytical Chemistry at Regeneron Pharmaceuticals 🏢, a leading biotech company. His expertise lies in mass spectrometry applications for protein characterization 🔬, contributing to advancements in therapeutic development. Before joining Regeneron, Dr. Xiao held esteemed faculty positions at Albert Einstein College of Medicine 🧬, progressing from Instructor to Research Associate Professor. His extensive research and leadership have played a crucial role in bridging analytical chemistry with biopharmaceutical innovation, impacting drug discovery and development. 🚀

Scientific Contributions

Dr. Hui Xiao 🎓 is a leading expert in protein-ligand interactions, structural proteomics, and therapeutic protein analysis 🔬. His pioneering work includes the application of hydrogen-deuterium exchange mass spectrometry (HDX-MS) for epitope mapping 🧩 and microtubule stabilization research. With a deep focus on drug characterization and regulatory sciences, his contributions have significantly advanced biopharmaceutical development 💊. His expertise in mass spectrometry-driven protein analysis has helped enhance the understanding of molecular mechanisms, improving therapeutic strategies. Through innovation and research, Dr. Xiao continues to play a vital role in shaping the future of biopharmaceutical science and drug discovery. 🚀

Potential Considerations

Dr. Hui Xiao 🎓 is a renowned expert in analytical and protein chemistry, with groundbreaking work in epitope mapping and protein characterization 🔬. While his contributions significantly impact drug development, the Pharmaceutical Innovation Achievement Award 🏆 may prioritize direct advancements in drug discovery and novel pharmaceutical interventions 💊. His research has important regulatory and therapeutic implications, but highlighting specific drug innovations or regulatory breakthroughs he has led would further strengthen his case. By showcasing his role in pioneering pharmaceutical advancements, Dr. Xiao’s influence in shaping modern biopharmaceutical science can be fully recognized and appreciated. 🚀

Research Focus

Dr. Hui Xiao’s research primarily focuses on analytical chemistry 🧪, particularly in the quantitative analysis of biomolecules 🧬 using advanced mass spectrometry techniques ⚖️. His work involves CRISPR sgRNA modification analysis 🧬🔬 and the development of LC-MS-based assays for biological therapeutics 💊. He specializes in phosphorothioate isomer detection 🔄 and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS) 📊 for precise biomolecular quantification. His contributions are crucial in drug discovery 🏥, gene editing 🧬, and biopharmaceutical development 💉. His expertise bridges biotechnology 🔬 and analytical methodologies 📈, advancing innovations in therapeutic monitoring and molecular diagnostics 🏥.

Publication Top Notes

Quantitative Analysis of Phosphorothioate Isomers in CRISPR sgRNA at Single-Residue Resolution Using Endonuclease Digestion Coupled with Liquid Chromatography Cyclic Ion Mobility Mass Spectrometry (LC/cIMS)

Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum

Prof. Mohamed Abdelzaher|Pharmacology | Best Researcher Award

Prof. Mohamed Abdelzaher, Pharmacology,Best Researcher Award

Prof. Mohamed Abdelzaher, at Environmental Science and Industrial Development Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University,Egypt

PROFILE

scopus

Early Academic Pursuits 🎓

Mohamed Abuelseoud Abdelzaher embarked on his academic journey at Minia University, where he pursued a Bachelor of Science degree at the Faculty of Science. His passion for environmental science led him to further his studies, culminating in an MSc in Environmental Chemistry from the same institution. His master’s thesis focused on the physico-chemical properties of sewage sludge ash blended cement pastes, a topic that underscored his growing interest in sustainable construction materials. His academic pursuits did not stop there, as he later achieved a Ph.D. in Environmental Science and Industrial Development from the Faculty of Postgraduate Studies for Advanced Sciences at Beni-Suef University in 2019. His doctoral research delved into enhancing the physico-mechanical properties of white cement through the application of nanoparticles, highlighting his commitment to advancing materials science and its environmental implications.

Professional Endeavors 🏢

Dr. Abdelzaher’s professional career began in the industrial sector, where he worked as a Quality Control and Labs Manager at Italcementi Group, Helwan Cement Co., from 2005 to 2017. This role allowed him to gain substantial experience in quality assurance and environmental management within the cement industry. His work in this capacity was instrumental in ensuring that the company adhered to stringent environmental and quality standards, contributing to the sustainability of its operations.

In 2017, Dr. Abdelzaher transitioned into academia, taking on the role of Assistant Professor of Environmental Science and Industrial Development at Beni-Suef University’s Faculty of Postgraduate Studies for Advanced Sciences. In this role, he has been actively involved in teaching, research, and mentorship, guiding the next generation of environmental scientists and engineers. His professional journey reflects a seamless blend of industry experience and academic expertise, making him a respected figure in both fields.

Contributions and Research Focus 🔬

Dr. Abdelzaher’s research is primarily centered on the application of nanomaterials in construction materials and environmental science, with a particular emphasis on waste management. His work on enhancing the properties of white cement using nanoparticles is a testament to his innovative approach to solving environmental and industrial challenges. By integrating cutting-edge nanotechnology into traditional construction materials, he has contributed to the development of more durable and sustainable building solutions.

In addition to his research in construction materials, Dr. Abdelzaher has also made significant contributions to environmental science, particularly in the area of waste management. His work explores how waste materials can be repurposed and utilized in environmentally friendly ways, thereby reducing their impact on the environment and contributing to a circular economy.

Accolades and Recognition 🏅

Throughout his career, Dr. Abdelzaher has received numerous accolades and certifications that attest to his expertise and leadership in his field. He is a certified environmental specialist, having received recognition from the Egyptian Ministry of Environment. He also holds an MBA from Ain Shams University, which complements his scientific expertise with strong business acumen.

Dr. Abdelzaher’s leadership skills have been recognized on an international level, as evidenced by his fellowship from the Science Leadership Program in Africa. This fellowship highlights his role as a thought leader in environmental science, particularly in the context of developing nations. Additionally, he has been awarded fellowships for curriculum development and environmental management, further underscoring his contributions to academia and industry alike.

Impact and Influence 🌍

Dr. Abdelzaher’s work has had a profound impact on both the academic community and the industrial sector. His research on nanomaterials and waste management has influenced the development of more sustainable construction practices, contributing to the global push towards greener building solutions. His teachings and mentorship at Beni-Suef University have inspired countless students to pursue careers in environmental science, ensuring that his influence will be felt for generations to come.

Moreover, his involvement in various professional organizations and his role as a reviewer for environmental journals published by Elsevier demonstrate his commitment to advancing the field of environmental science. Through these roles, he has helped shape the direction of research and development in his field, ensuring that it continues to address the most pressing environmental challenges of our time.

Legacy and Future Contributions 🚀

As Dr. Abdelzaher continues his career, his legacy is one of innovation, leadership, and dedication to sustainability. His work in nanotechnology and waste management has laid the groundwork for future advancements in these fields, and his influence as an educator ensures that his knowledge and expertise will be passed on to the next generation of environmental scientists.

🎓Publication 

Effective impact of nano-plastic-waste incorporated with nanotitina on the physical, mechanical and microstructural properties of white cement pastes composites for progressing towards sustainability

  • Authors   :Abdelzaher, M.A., Farghali, A.A., Hamouda, A.S.
  • Journal    :Scientific Reports
  • Year         :2024

Production, characterization and performance of green geopolymer modified with industrial by-products

    • Authors :Abbas, R., Abdelzaher, M.A., Shehata, N., Tantawy, M.A.
    • Journal   :Scientific Report
    • Year       : 2024

Effect of ginger, chamomile, and green tea extracts on prostate cancer cells

Bacterial biodegradation of oil-contaminated soil for pollutant abatement contributing to achieve sustainable development goals: A comprehensive review

  • Authors  :Aziz, Z.S., Jazza, S.H., Dageem, H.N., Balboul, B.A., Abdelzaher, M.A.
  • Journal   :Results in Engineering
  • Year        :   2024

Experimental and Theoretical Study of Water Amount on the Rheological Features of Marble Sludge Grout