Chen Xie | Gene Therapy | Best Researcher Award

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Chen Xie | Gene Therapy | Best Researcher Award

Assoc. Prof. Dr. Chen Xie, Medical Research Center, the Eighth Affiliated Hospital of Sun Yat-sen University, China

Assoc. Prof. Dr. Chen Xie is a distinguished researcher at the Medical Research Center, Eighth Affiliated Hospital of Sun Yat-Sen University. With a Ph.D. in Biochemical Engineering from Huaqiao University and postdoctoral experience in genetics at Sun Yat-Sen University, his work focuses on inflammation, DNA damage, senescence, and noncoding RNAs. 🧬 He has published eight impactful papers in journals such as Signal Transduct Target Ther, Mol Cell, and Cancer Immunol Res and holds an H-index of 9. πŸ§ͺ Dr. Xie is a recipient of multiple national honors and leads NSFC-funded research advancing disease-related molecular mechanisms.

Publication Profile

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Education

Assoc. Prof. Dr. Chen Xie is a dedicated researcher with a strong background in biochemical and genetic sciences. He began his academic journey with a Bachelor’s degree in Bioengineering from Huaqiao University πŸŽ“ (2007–2011), followed by a Master’s in Genetics from Sun Yat-Sen University πŸ”¬ (2011–2014). He earned his Ph.D. in Biochemical Engineering in 2018 πŸ§ͺ. Dr. Xie completed a postdoctoral fellowship at Sun Yat-Sen University (2018–2021), and then served as Assistant Professor (2021–2025). Since March 2025, he has been an Associate Professor at the Medical Research Center, Eighth Affiliated Hospital of Sun Yat-Sen University πŸ₯, advancing biomedical research.

Experience

Assoc. Prof. Dr. Chen Xie mainly focuses on exploring the intricate relationship between inflammation, DNA damage, cellular senescence, noncoding RNAs, and human diseases 🧬. His impactful research has earned him prestigious honors such as the National Natural Science Foundation of China award, the National Scholarship πŸ…, the First Prize Scholarship of Huaqiao University, and the Alumni Scholarship πŸŽ“. Dr. Xie has published 8 influential papers in top-tier journals including Signal Transduction and Targeted Therapy, Molecular Cell, and Cancer Immunology Research πŸ“š. With an H-index of 9, he continues to contribute significantly to biomedical science 🧫.

Awards

Assoc. Prof. Dr. Chen Xie has received several prestigious awards in recognition of his academic excellence and research contributions πŸŽ“. He was honored with a National Scholarship for his outstanding performance and dedication to scientific advancement. During his studies at Huaqiao University, he earned the First Prize Scholarship πŸ₯‡, highlighting his exceptional academic achievements. Additionally, he received an Alumni Scholarship, reflecting the strong support and recognition from his academic community 🌟. These accolades underscore Dr. Xie’s commitment to excellence in the fields of biochemical engineering, genetics, and biomedical research πŸ”¬.

Research Focus

Assoc. Prof. Dr. Chen Xie is a leading researcher in the fields of molecular biology, epigenetics, and cellular senescence, with a strong emphasis on mechanisms of vascular and pulmonary aging, DNA damage repair, and RNA modifications (e.g., m6A). 🧬 His work uncovers how factors like GATA6, YTHDC1, and FTO regulate aging, fibrosis, cancer, and immune responses, often via intricate signaling pathways and RNA interactions. 🧠🧫 He contributes significantly to understanding vascular calcification, fibrosis, and glioma biology, advancing targeted therapies. His research bridges cellular aging and precision medicine, making a profound impact on age-related and inflammatory diseases.

Publication Top Notes

The transcription factor GATA6 accelerates vascular smooth muscle cell senescence-related arterial calcification by counteracting the role of anti-aging factor SIRT6 and impeding DNA damage repair

YTHDC1 delays cellular senescence and pulmonary fibrosis by activating ATR in an m6A-independent manner

C5a-C5aR1 induces endoplasmic reticulum stress to accelerate vascular calcification <i>via</i> PERK-eIF2Ξ±-ATF4-CREB3L1 pathway

UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1

Data from FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma

Supplementary Data from FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma

cGAS guards against chromosome end-to-end fusions during mitosis and facilitates replicative senescence

Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7

SON DINH PHONG | Gene Therapy | Best Researcher Award

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SON DINH PHONG | Gene Therapy | Best Researcher Award

Dr SON DINH PHONG, DUYTAN UNIVERSITY, Vietnam

Dr. Dinh Phong Son is a dedicated researcher in molecular medicine at Duy Tan University, Vietnam. With a Ph.D. from Guangxi Medical University, China, and a background in laboratory medicine from Hue University of Medicine and Pharmacy, his research focuses on molecular biomarkers for early disease detection πŸ§ͺπŸ”¬. He explores the LncRNA/CircRNA/miRNA/gene/protein-drug interaction network and gene-editing techniques like CRISPR/Cas9 for targeted therapy. His work on cardiovascular disease and cancer diagnostics has been published in prestigious journals πŸ“šπŸ§‘β€πŸ”¬. Passionate about advancing molecular biology, he aspires to contribute to innovative breakthroughs in disease research.

Publication Profile

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Education

Dr. Dinh Phong Son πŸŽ“ holds a degree in Laboratory Medicine Technique from Hue University of Medicine and Pharmacy, Vietnam, and a Ph.D. in Molecular Medicine from Guangxi Medical University, China. 🧬 His expertise lies in molecular biology, with a strong focus on disease biomarkers and gene-targeted therapies. πŸ₯πŸ”¬ With a solid academic foundation, he has contributed significantly to scientific advancements, particularly in precision medicine and diagnostics. His research aims to enhance medical treatments by identifying key genetic markers, paving the way for innovative therapeutic approaches. 🌍✨ Dr. Son’s dedication to science continues to drive breakthroughs in healthcare. πŸ’‘πŸ‘¨β€βš•οΈ

Research and Innovations

Dr. Son Dinh Phong πŸ”¬ is deeply engaged in advancing molecular biology through next-generation sequencing and online medical databases. His primary focus is identifying potential biomarkers for early disease detection, including diabetes, cardiovascular diseases, stroke, and cancer. 🧬🩺 His research also explores gene-targeted therapies, utilizing CRISPR/Cas9 for gene editing, overexpression, and silencing. πŸ₯ His studies on LncRNA/CircRNA/miRNA/gene/protein-drug interaction networks provide a foundation for future medical breakthroughs. πŸ“Šβœ¨ Committed to innovation, Dr. Son’s ongoing work (2023-2025) aims to drive scientific progress, hoping for greater support to expand molecular biology research worldwide. πŸŒπŸ’‘

Research Contributions

Dr. Son Dinh Phong πŸ”¬ is highly proficient in advanced molecular biology techniques, including PCR, qPCR, and sequencing analysis πŸ§ͺ🧬. He specializes in CRISPR/Cas9 genome editing, RNA silencing, and overexpression assays, contributing to groundbreaking gene therapy research. πŸ₯ His expertise also includes cell culture, western blotting, and fluorescence in situ hybridization, essential for studying gene expression and protein interactions. πŸ”πŸ§« Additionally, he excels in bioinformatics and molecular docking simulations, enabling in-depth analysis of gene interactions and drug responses. πŸ’»πŸ’Š With a strong foundation in computational biology, Dr. Son continues to drive innovation in precision medicine and molecular diagnostics. πŸš€βœ¨

Editorial Appointments

Dr. Son Dinh Phong πŸŒπŸ”¬ actively contributes to the global scientific community through his extensive research and publications. While specific editorial roles, consultancy projects, or industry collaborations may not be listed, his scholarly work reflects deep engagement in molecular biology and precision medicine. πŸ§¬πŸ“– His ORCID profile further validates his impactful contributions, showcasing his dedication to advancing medical research. πŸ₯✨ Through collaborations and scientific discourse, Dr. Son continues to push the boundaries of innovation, striving to enhance disease diagnostics and therapeutic strategies. His commitment to research ensures lasting contributions to the ever-evolving field of molecular medicine. πŸ’‘πŸš€

Research Focus

Dr. Son Dinh Phong’s research primarily focuses on cardiovascular diseases πŸ«€, non-coding RNAs 🧬, and bioinformatics-driven biomarker discovery πŸ–₯️. His work explores circular RNAs (circRNAs) and microRNAs (miRNAs) in coronary heart disease (CHD) πŸ₯, revealing their role as competing endogenous RNAs (ceRNAs) in gene regulation. Additionally, he investigates serum miRNAs as potential diagnostic biomarkers for various cancers πŸŽ—οΈ and employs computational approaches πŸ”¬ to identify key regulatory networks in diseases like latent tuberculosis 🦠. His studies integrate molecular biology, genomics, and systems biology to advance precision medicine 🎯 and therapeutic innovations πŸ’Š for complex diseases.

Publication Top Notes

Identification and assessment of hub genes and miRNAs coregulatory associated with immune infiltrations and drug interactions in latent tuberculosis based on MicroarrayData analysis, molecular docking, and dynamic simulation

Hsa_circRNA_0000284 acts as a ceRNA to participate in coronary heart disease progression by sponging miRNA-338-3p via regulating the expression of ETS1

Potential diagnostic value of serum microRNAs for 19 cancer types: a meta-analysis of bioinformatics data

Identification of hsa_circ_0001445 of a novel circRNA-miRNA-mRNA regulatory network as potential biomarker for coronary heart disease

Construction of miRNAs and gene expression profiles associated with ischemic cardiomyopathy: Bioinformatics analysis