Awatef Sassi | Drug Discovery and Development | Women Researcher Award

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Awatef Sassi | Drug Discovery and Development | Women Researcher Award

Dr. Awatef Sassi, Faculty of medicine of sousse, Tunisia

Dr. Awatef Sassi 🧬🔬 is a distinguished postdoctoral researcher at the Faculty of Medicine of Sousse, specializing in cardiovascular and metabolic research. She earned her Ph.D. in Biological Sciences (2018) from the Faculty of Science of Bizerte, following a Master’s in Vascular Diseases Biology (2011) and a Medical Biotechnology degree (2008). Dr. Sassi has contributed significantly to scientific advancements, securing a patent on anti-hypertensive properties of Rosmarinus officinalis and publishing in high-impact journals. She is actively involved in mentoring medical theses and conducting innovative research in biophysics and applied toxicology. 🌿📊

Publication Profile

Orcid

Education

Dr. Awatef Sassi is a distinguished scholar in biological sciences 🧬, biotechnology 🏥, and vascular diseases ❤️. With a Ph.D. in Biological Sciences 🎓, a Master’s in Vascular Disease Biology, and a Medical Biotechnology degree, she has demonstrated an unwavering commitment to scientific research 🔬. Her extensive expertise spans innovative biotechnological applications and advancements in vascular health, contributing significantly to the medical and scientific communities. Dr. Sassi’s dedication to excellence and groundbreaking research continues to shape the future of biotechnology and vascular medicine, making her a respected figure in the field 🌟.

Experience 

Dr. Awatef Sassi’s postdoctoral research at the Faculty of Medicine in Sousse 🏥 has focused on cardio-pulmonary interactions 💓💨 and biophysics ⚛️, making significant contributions to biomedical sciences. As a dedicated mentor, she has supervised multiple medical theses 📚, showcasing her leadership in academia. Her patented innovation 🏅 on the antihypertensive activity of Rosmarinus officinalis 🌿 (TN 2023/0143) highlights groundbreaking research with potential clinical impact in hypertension treatment 💊. Through her pioneering work, Dr. Sassi continues to advance medical science, bridging research and practical healthcare solutions for improved cardiovascular health ❤️.

Professional Development

Dr. Awatef Sassi is a dedicated educator and researcher 🎓🔬, with extensive experience as a lecturer in analytical chemistry ⚗️. Her involvement in postgraduate training 📚 has strengthened expertise in HPLC/UPLC 💉, mass spectrometry 🧪, and data analysis (SPSS) 📊. Through her teaching and mentorship, she equips students and researchers with essential analytical and computational skills, fostering scientific excellence. Dr. Sassi’s commitment to professional development ensures that future scientists gain hands-on experience in advanced laboratory techniques, making a lasting impact in biotechnology, pharmacology, and medical sciences 🏥🌿.

Research Focus

Dr. Awatef Sassi’s research primarily focuses on phytomedicine 🌿, clinical nutrition 🥗, cardiovascular health ❤️, and pharmaceutical sciences 💊. Her work explores the therapeutic potential of medicinal plants like Rosmarinus officinalis and Nitraria retusa for conditions such as hypertension, obesity, and lipid disorders. Additionally, she has contributed to cardiovascular interventions 🏥, dermatological formulations, and transfusion medicine 🩸. Her studies include randomized clinical trials, pilot studies, and formulation research, highlighting her interdisciplinary approach to natural product-based therapy and clinical pharmacology. Her work significantly impacts personalized medicine, preventive healthcare, and alternative treatment strategies.

Publication Top Notes

The Effect of Rosmarinus officinalis L Infusion Supplementation on Blood Pressure Among Healthy Volunteers and Grade 1 Hypertensive Patients

Antiobesity and Hypolipidemic Potential of Nitraria retusa Extract in Overweight/Obese Women: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Exploring the Effects of Short-Term Daily Intake of Nitraria retusa Tea on Lipid Profile: A Pre-Post, Uncontrolled Pilot Study in Both Healthy and Overweight/Obese Adults

Distal radial approach versus conventional radial approach: a comparative study of feasibility and safety

Formulation and evaluation of topical halofuginone gel using a novel <I>ex vivo</i> model

RHD genotyping and its implication in transfusion practice

Johan Alexander Villada Ramos | Drug Discovery and Development | Best Researcher Award

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Johan Alexander Villada Ramos | Drug Discovery and Development | Best Researcher Award

Prof. Johan Alexander Villada Ramos, Universidad del Quindío, Colombia

Johan Alexander Villada Ramos is a Ph.D. candidate in Sciences at Universidad del Quindío, specializing in natural alternatives to synthetic pesticides 🌱🦠. He holds a Master’s in Biomedical Sciences, earning a meritorious distinction 🏅, and a Biology degree. His research spans bioactive plant compounds, cancer prevention, and lipid metabolism. As a university lecturer 📚, he teaches molecular biology and biochemistry. With multiple research projects, publications, and awards, including the Carlos Corredor Pereira National Award in Biomedical Sciences (2024) 🏆, Johan is a dedicated scientist pushing the boundaries of biotechnology and microbiology.

Publication Profile

Orcid

Education

Prof. Johan Alexander Villada Ramos 🎓 is a doctoral student in Sciences at the Universidad del Quindío, focusing on the bioactivity of free and microencapsulated Tagetes erecta L. 🌿 as an alternative to synthetic pesticides against the avocado weevil Heilipus lauri 🥑. He earned a Master’s in Biomedical Sciences (2018–2022) with meritorious distinction 🏅, researching the effects of Passiflora edulis extract on lipid metabolism enzymes in human colorectal adenocarcinoma cells. His Biology degree (2013–2018) involved evaluating the antibacterial activity of Tagetes patula L. against Ralstonia solanacearum. Additionally, he trained in microbiology and biotechnology lab preparation at SENA (2017–2018) 🔬.

Professional Achievements

Prof. Johan Alexander Villada Ramos 🎓 has made significant contributions to biomedical and biological research. He earned a meritorious distinction 🏅 for his master’s research on Passiflora edulis 🍊 and its effects on lipid metabolism in colorectal cancer cells. Holding a Biology degree 🔬, his studies focused on the antimicrobial activity of plant extracts against pathogens. He has been actively involved in high-impact research projects 📚 at prestigious institutions, including Pontificia Universidad Javeriana and Universidad del Quindío. His work continues to advance natural alternatives 🌱 in disease management, reinforcing his dedication to scientific discovery and innovation.

Leadership in Academia

Prof. Johan Alexander Villada Ramos 🎓 is a dedicated academic leader, serving as a lecturer 📖 in molecular biology, biochemistry, and microbiology 🔬 at Universidad del Quindío. Passionate about education, he actively contributes to curriculum development 🏫, ensuring that students receive up-to-date and high-quality training. Additionally, he plays a key role in laboratory training 🧪, equipping future scientists with essential research skills. His commitment to fostering scientific knowledge and practical expertise strengthens the university’s academic foundation, inspiring students to excel in the fields of biotechnology, microbiology, and biomedical sciences. 🚀

Research Focus

Prof. Johan Alexander Villada Ramos specializes in natural product chemistry, biochemistry, and phytopharmacology, with a strong focus on the antioxidant, antibacterial, and anticancer properties of plant extracts. His research explores bioactive compounds from medicinal plants, such as Coffea arabica ☕, Passiflora edulis 🍃, and Tagetes patula 🌼, investigating their effects on oxidative stress, protein oxidation, and bacterial inhibition 🦠. His studies contribute to pharmaceutical development, food science, and biomedicine, aiming to harness plant-derived compounds for disease prevention and therapeutic applications. 🏥

Publication Top Notes

Potencial antioxidante del extracto de hoja de Coffea arabica sobre la lipoperoxidación y oxidación proteica en un modelo de músculo bovino

Identification of potential bioactive compounds of Passiflora edulis leaf extract against colon adenocarcinoma cells

Evaluation of antibacterial activity of extract and essential oil of Tagetes patula L. in vitro against Ralstonia solanacearum biovar 2

Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

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Hui Xiao | Drug Discovery and Development | Pharmaceutical Innovation Achievement Award

Dr Hui Xiao,regeneron,United States

Dr. Hui Xiao 🧪🔬 is a distinguished scientist specializing in biochemistry, structural biology, and mass spectrometry. With a strong focus on microtubule dynamics, protein interactions, and drug mechanisms, he has made significant contributions to understanding cellular processes. As a co-first author and lead researcher, his work has been published in esteemed journals like J. Mol. Biol., Biochemistry, and J. Biol. Chem.. His expertise spans hydrogen-deuterium exchange, proteomics, and molecular stabilization studies. Dr. Xiao’s research has advanced drug discovery, particularly in cancer therapeutics and protein biochemistry. 📚🔍 His innovative approaches continue to impact biomedical sciences globally. 🌍✨

Publication Profile

Scopus

Education

Dr. Hui Xiao 🎓 holds a Ph.D. in Analytical Chemistry from the University of Massachusetts, Amherst (2005) and a degree in Applied Chemistry from Peking University, China (1992). Currently serving as an Associate Director at Regeneron Pharmaceuticals 🏢, he specializes in protein characterization using mass spectrometry. With over a decade at Regeneron, he has progressed through roles as a Senior Staff Scientist and Staff Scientist. Previously, he held academic positions at Albert Einstein College of Medicine 🧬, advancing from Instructor to Research Associate Professor. His expertise spans analytical chemistry, protein analysis, and therapeutic protein research, making significant contributions to biomedical science. 🔬

Professional Impact

Dr. Hui Xiao 🎓 is a distinguished scientist with over 20 years of experience in academia and the biotechnology industry. Currently, he serves as an Associate Director of Analytical Chemistry at Regeneron Pharmaceuticals 🏢, a leading biotech company. His expertise lies in mass spectrometry applications for protein characterization 🔬, contributing to advancements in therapeutic development. Before joining Regeneron, Dr. Xiao held esteemed faculty positions at Albert Einstein College of Medicine 🧬, progressing from Instructor to Research Associate Professor. His extensive research and leadership have played a crucial role in bridging analytical chemistry with biopharmaceutical innovation, impacting drug discovery and development. 🚀

Scientific Contributions

Dr. Hui Xiao 🎓 is a leading expert in protein-ligand interactions, structural proteomics, and therapeutic protein analysis 🔬. His pioneering work includes the application of hydrogen-deuterium exchange mass spectrometry (HDX-MS) for epitope mapping 🧩 and microtubule stabilization research. With a deep focus on drug characterization and regulatory sciences, his contributions have significantly advanced biopharmaceutical development 💊. His expertise in mass spectrometry-driven protein analysis has helped enhance the understanding of molecular mechanisms, improving therapeutic strategies. Through innovation and research, Dr. Xiao continues to play a vital role in shaping the future of biopharmaceutical science and drug discovery. 🚀

Potential Considerations

Dr. Hui Xiao 🎓 is a renowned expert in analytical and protein chemistry, with groundbreaking work in epitope mapping and protein characterization 🔬. While his contributions significantly impact drug development, the Pharmaceutical Innovation Achievement Award 🏆 may prioritize direct advancements in drug discovery and novel pharmaceutical interventions 💊. His research has important regulatory and therapeutic implications, but highlighting specific drug innovations or regulatory breakthroughs he has led would further strengthen his case. By showcasing his role in pioneering pharmaceutical advancements, Dr. Xiao’s influence in shaping modern biopharmaceutical science can be fully recognized and appreciated. 🚀

Research Focus

Dr. Hui Xiao’s research primarily focuses on analytical chemistry 🧪, particularly in the quantitative analysis of biomolecules 🧬 using advanced mass spectrometry techniques ⚖️. His work involves CRISPR sgRNA modification analysis 🧬🔬 and the development of LC-MS-based assays for biological therapeutics 💊. He specializes in phosphorothioate isomer detection 🔄 and liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS) 📊 for precise biomolecular quantification. His contributions are crucial in drug discovery 🏥, gene editing 🧬, and biopharmaceutical development 💉. His expertise bridges biotechnology 🔬 and analytical methodologies 📈, advancing innovations in therapeutic monitoring and molecular diagnostics 🏥.

Publication Top Notes

Quantitative Analysis of Phosphorothioate Isomers in CRISPR sgRNA at Single-Residue Resolution Using Endonuclease Digestion Coupled with Liquid Chromatography Cyclic Ion Mobility Mass Spectrometry (LC/cIMS)

Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum