Dr. Chinedum Ekeleme at Delta State University of Science and Technology Ozoro,Nigeria
PROFILE
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🎓Summary
Chinedum Martins Ekeleme is a skilled biochemist with extensive experience in metabolic disease research, particularly focusing on lipid metabolism, adipose tissue function, and the impact of natural extracts on metabolic signaling. He has demonstrated proficiency in using molecular biology techniques, animal models, bioinformatics, and advanced data analysis to advance understanding in metabolic diseases. His commitment to education is reflected in his role as a research advisor for graduate students and a dedicated mentor in the academic community.
Education
Ph.D. in Biochemistry (2018 – 2023)
University of Calabar, Cross River State, Nigeria
- Research Focus: Molecular regulatory mechanisms in lipid metabolism, adipose tissue function, and metabolic signaling pathways, specifically examining the effects of Alchornea cordifolia extract on high-fat diet-induced obesity models.
Professional Experience
Ph.D. Researcher
University of Calabar, Nigeria (2018 – 2023)
- Investigated lipid metabolism under high-fat diet conditions using glucose tolerance tests, lipid profiles, histopathological microscopy, and mass spectrometry.
- Contributed to systemic lipid metabolism research, focusing on adipocytes, liver function, and obesity-related pathways.
Student Research Advisor & Data Analyst (Freelance/Remote)
(2018 – 2024)
- Guided BSc, MSc, and PhD students on experimental design, data collection, and analysis, particularly related to metabolic diseases.
- Assisted in drafting and revising research manuscripts and provided training in data management and biological sample collection.
Volunteer Research Fellow/Assistant
Michael Okpara University of Agriculture Umudike (Feb 2015 – May 2018)
- Trained and supervised undergraduate and graduate students, assisting with experiments and data analysis for disease models.
- Managed chemical inventory and facilitated technical problem-solving in metabolic research.
Intern – Virology and Molecular Diagnostics Lab
International Institute of Tropical Agriculture (IITA) (Apr – Sep 2011)
- Conducted DNA/RNA extraction, PCR, gel electrophoresis, and PAGE analysis.
Academic Cites
- Ekeleme, C.M., et al. (2022). Impact of Alchornea cordifolia Extract on Lipid Metabolism and Adipose Tissue Function in Obesity Models. Journal of Biochemical Research.
- Ekeleme, C.M., et al. (2021). Molecular Pathways Involved in Obesity and Adipocyte Metabolism. African Journal of Metabolic Studies.
Technical Skills
- Molecular Biology: PCR, Western blotting, ELISA, gene cloning, sequencing.
- Metabolic Assays: Glucose tolerance, insulin sensitivity, lactate production measurement.
- Animal Models: Expertise in handling and conducting experiments on in vivo metabolic disease models.
- Bioinformatics: Gene expression analysis, metabolic pathway analysis using bioinformatics tools.
- Computational Skills: Density functional theory (DFT) and molecular docking simulations.
- Software: MS Excel, GraphPad, ImageJ, R, Python.
Teaching Experience
- Lecturer: Delta State University of Science and Technology, Ozoro (2023 – Present).
- Teach courses in biochemistry and metabolic disease mechanisms.
- Supervise undergraduate and graduate students in research projects.
Research Interests
- Lipid metabolism and adipose tissue function.
- Metabolic diseases, particularly obesity, insulin resistance, and related disorders.
- Natural products and their impact on metabolic regulation.
- Bioinformatics analysis of metabolic pathways.
- Development and application of experimental models for metabolic research.