Xu Yufen | Drug Discovery and Development | Best Researcher Award

Dr. Xu Yufen | Drug Discovery and Development | Best Researcher Award

The Affiliated Hospital of Jiaxing University | China

Dr. Xu Yufen, Ph.D. in Medicine and Associate Professor at Jiaxing University, has emerged as a dedicated academic and clinical researcher in the field of chest tumors, with a strong focus on lung cancer, esophageal cancer, and thymoma. Her academic and professional journey reflects a unique blend of clinical insight and rigorous scientific research, bridging traditional and modern medical practices to address some of the most pressing challenges in oncology.Her research portfolio encompasses multiple completed and ongoing projects, including significant contributions to the Zhejiang Provincial Science and Technology Program in Traditional Chinese Medicine and Jiaxing City’s Science and Technology Program. Presently, she is leading three active research projects aimed at developing innovative therapeutic strategies and improving patient outcomes in chest oncology. Her studies demonstrate a strong commitment to integrating clinical experience with advanced research methodologies, paving the way for evidence-based, patient-centered cancer care.Dr. Xu’s scholarly impact is reflected in her extensive publication record in high-quality journals indexed in SCI and Scopus. Notable works include Development and Validation of a Prognostic Nomogram for Early Stage Non-Small Cell Lung Cancer: A Study Based on the SEER Database and a Chinese Cohort, Effect of Postoperative Radiotherapy on Survival in Patients with Completely Resected and Pathologically Confirmed Stage N2 Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis, LncRNA HCG11 Enhances the Chemosensitivity of Non-Small Cell Lung Cancer Cells to Gemcitabine via miR-17-5p/p21 Axis, and Akkermansia Muciniphila Outer Membrane Protein Regulates Recruitment of CD8+ T Cells in Lung Adenocarcinoma and Through JAK–STAT Signalling Pathway. These publications highlight her expertise in clinical oncology research, molecular biology, and the exploration of novel therapeutic targets.Her contributions to the academic community extend beyond research. Dr. Xu has been actively involved in professional organizations such as the Second Youth Committee of the Cancer Support Treatment Committee of the Zhejiang Society of Mathematical Medicine, the Chinese Society of Clinical Oncology’s expert committee on integrated traditional and Western medicine, and the Youth Committee of the Zhejiang Medical Association Oncology Branch. Through these roles, she fosters collaboration, knowledge-sharing, and the translation of research findings into clinical practice.

Profile: Scopus

Featured Publications

Authors Unknown. (2024). Akkermansia muciniphila outer membrane protein regulates recruitment of CD8+ T cells in lung adenocarcinoma and through JAK–STAT signalling pathway. Microbial Biotechnology.

Authors Unknown. (n.d.). Research progress in the therapeutic application of traditional Chinese medicine for postoperative cough in patients with lung cancer. Journal Name Unknown.

Authors Unknown. (n.d.). LncRNA HCG11 enhances the chemosensitivity of non-small cell lung cancer cells to Gemcitabine via miR-17-5p/p21 axis. Expert Review of Anticancer Therapy.

Matlou Mokgotho | Drug Discovery and Development | Best Researcher Award

Prof. Dr. Matlou Mokgotho | Drug Discovery and Development | Best Researcher Award

Lecturer at Sefako Makgatho Health Science University | South Africa

Prof. Dr. Matlou Mokgotho is a distinguished biochemist and academic leader with over two decades of experience in higher education, research, and community development. Currently a Senior Lecturer at Tshwane University of Technology, he has previously served as Professor and Head of Department of Biochemistry at the University of Limpopo. His expertise spans molecular biology, proteomics, bioenergetics, enzymology, and mammalian cell cultures. Beyond academia, Dr. Mokgotho has actively contributed to community health awareness initiatives, youth leadership, and ethical oversight in research and professional bodies. His leadership, research excellence, and dedication to mentorship continue to inspire future scientists in South Africa.

Publication Profile 

Orcid

Education 

Prof. Dr. Matlou Mokgotho holds a Doctor of Philosophy in Biochemistry from the University of Limpopo, conferred. He earned his Master of Science in Biochemistry his Bachelor of Science Honours in Biochemistry  both from the University of the North. He also completed a Bachelor of Science in Biochemistry and Microbiology at the same institution. His academic foundation was laid at Seshigo High School, where he obtained his Senior Certificate. This strong educational background provided him with the knowledge and skills to excel in biochemical sciences and academic leadership.

Experience 

Prof. Dr. Matlou Mokgotho career spans roles from tutor to senior lecturer, professor, and department head. He began lecturing in Biochemistry at the University of the North before joining the University of Limpopo, where he advanced to Professor and Head of Department. His teaching portfolio covers biochemistry, molecular biology, proteomics, cell culture, and bioenergetics. He also served as CEO of Milestevens Development and Properties, showcasing leadership in management. Currently, he is Senior Lecturer at Tshwane University of Technology and a module critical reader at UNISA. His responsibilities include teaching, research coordination, and academic mentorship.

Awards and Honors 

Prof. Dr. Matlou Mokgotho has been recognized for his academic, community, and leadership contributions. He received certificates for AIDS Awareness campaigns and laboratory assistance during his early career, highlighting his dedication to education and health promotion. His leadership in youth and church organizations earned him certificates of moral leadership and community service, while his active role in HIV/AIDS awareness workshops reflected his commitment to social impact. As a council member of the South African Dental Technician Council, he contributed to professional ethics and governance. These accolades underscore his commitment to advancing science, leadership, and community development.

Research Focus 

Prof. Dr. Matlou Mokgotho research focuses on biochemistry, molecular biology, and proteomics, with a special interest in bioenergetics, protein structure-function relationships, and mammalian cell cultures. His work bridges fundamental and applied science, exploring enzymology, molecular mechanisms, and the applications of cell cultures in medical research. He has also contributed to developing experimental methodologies and training students in proposal writing, research principles, and dissertation development. His commitment to advancing biochemistry is reflected in his integration of teaching, research, and community engagement, with a strong emphasis on preparing students for careers in molecular science and addressing health challenges through biotechnological approaches.

Publication Top Notes

Xiao Sheng | Drug Discovery and Development | Best Researcher Award

Dr. Xiao Sheng | Drug Discovery and Development | Best Researcher Award

lecturer at Naval Medical University School of Pharmacy | China

Dr. Xiao Sheng is a distinguished researcher in biochemistry and molecular biology at the Navy Medical University, China. His work bridges traditional Chinese medicine, molecular signaling, and intestinal health, with a focus on aging and regenerative biology. As a principal investigator of multiple funded projects, he has made significant contributions to understanding mechanisms of intestinal stem cell regulation, tumor progression, and herbal medicine efficacy. His publications in high-impact journals highlight pioneering findings in antioxidant pathways, stem cell biology, and gut regeneration. Dr. Xiao is actively engaged in international collaborations, scientific societies, and editorial responsibilities in biomedical research.

Publication Profile 

Orcid

Education 

Dr. Xiao Sheng completed his academic training in biochemistry and molecular biology, developing a strong foundation in cellular and molecular research. At the Navy Medical University, he pursued advanced education integrating biomedical sciences with translational research approaches. His education emphasized experimental medicine, molecular signaling pathways, and the application of traditional Chinese medicine concepts within modern biological frameworks. This interdisciplinary training enabled him to explore the interaction between cellular metabolism, intestinal regeneration, and aging biology. His academic preparation laid the groundwork for his later success as a principal investigator and contributed to his leadership in national and international scientific initiatives.

Experience 

Dr. Xiao Sheng  has extensive experience leading research in biochemistry, molecular biology, and translational medicine. As principal investigator, he heads projects supported by Anhui Provincial Engineering Technology Research Center and the Second Military Medical University, focusing on intestinal injury repair, tumor biology, and herbal medicine. His work extends to national research initiatives such as the National Key R&D Program and the National Natural Science Foundation of China, where he has contributed as a key participant. He has authored numerous peer-reviewed publications, serves on editorial boards, and holds active memberships in professional committees, advancing biomedical research and international scientific collaboration.

Awards and Honors 

Dr. Xiao Sheng has received multiple recognitions for his scientific contributions. He earned the Outstanding Poster Award at the International and Chinese Drosophila Biology Congress, demonstrating the novelty of his research in model organisms. His innovative approaches to Chinese medicine research were honored with the Third Prize in the Traditional Chinese Medicine Group at the National Undergraduate Forum on Innovative Research in Basic Medicine and Experimental Design. Recently, he was named a “Shizhen Scholar,” reflecting his leadership and excellence in integrating traditional medicine with modern molecular biology. These awards underscore his contributions to translational and interdisciplinary biomedical research.

Research Focus 

Dr. Xiao’s  Sheng  research centers on molecular mechanisms regulating intestinal stem cell biology, aging, and regenerative medicine. He explores how herbal medicine compounds influence cellular pathways, particularly the Keap1–Nrf2 signaling axis, to mitigate intestinal injury and aging-related disorders. His studies extend to tumor biology, focusing on how nuclear lamina proteins drive cancer development through cell competition. Additionally, he investigates molecular regulators of gut regeneration, including transcription factors and RNA modifications. His interdisciplinary approach combines traditional Chinese medicine with modern molecular biology, advancing novel therapeutic strategies. His work holds promise for improving treatments for age-related diseases and metabolic disorders.

Publication Top Notes

Unlocking nature’s medicine cabinet through Drosophila–Driven exploration

Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila

Phase separation of BuGZ regulates gut regeneration and aging through interaction with m6A regulators

Antioxidant Effects of Caffeic Acid Lead to Protection of Drosophila Intestinal Stem Cell Aging

Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila

Dr. Rocio Alejandra Chavez Santoscoy |Drug Discovery and Development| Best Researcher Award

Dr. Rocio Alejandra Chavez Santoscoy ,Drug Discovery and Development ,Best Researcher Award

Dr. Rocio Alejandra Chavez Santoscoy, at Tecnológico de Monterrey,Mexico

PROFILES

scopus
Orcid

 

📚Early Academic Pursuits :

The foundation of the research on Bacillus clausii and its novel delivery systems traces back to early academic pursuits in microbiology and biotechnology. Researchers embarked on this journey by gaining extensive knowledge in microbial physiology, genetics, and the complex interactions between probiotics and the human gut microbiome. This academic groundwork was crucial in understanding the significance of Bacillus clausii as a robust probiotic strain capable of withstanding harsh gastrointestinal conditions.

🧪Professional Endeavors :

Professional endeavors in this field have seen a significant focus on the development and optimization of microencapsulation techniques. Scientists and researchers dedicated their efforts to creating advanced delivery systems that protect probiotics from the acidic environment of the stomach and ensure their controlled release in the intestines. This involved interdisciplinary collaborations between microbiologists, food scientists, and biotechnologists, who worked together to design and test various non-digestible carbohydrate formulations. These endeavors were aimed at enhancing the stability, viability, and efficacy of Bacillus clausii in probiotic supplements and functional foods.

🔬Contributions and Research Focus :

The primary research focus has been on the microencapsulation and controlled release of Bacillus clausii using a novel non-digestible carbohydrate formulation. This approach leverages the protective properties of non-digestible carbohydrates, such as inulin, resistant starch, and pectin, to encapsulate the probiotic cells. The encapsulation process involves techniques like spray drying, freeze-drying, and extrusion, which help in forming a protective matrix around the probiotic cells. The key contributions of this research include:

  • Enhanced Stability: The novel formulation significantly improves the stability of Bacillus clausii during storage and transit through the gastrointestinal tract.
  • Controlled Release: The non-digestible carbohydrate matrix ensures a controlled and sustained release of the probiotics in the intestines, maximizing their beneficial effects.
  • Improved Efficacy: The formulation enhances the colonization and activity of Bacillus clausii in the gut, leading to better health outcomes for the host.

🏆Accolades and Recognition :

The groundbreaking work on the microencapsulation and controlled release of Bacillus clausii has garnered significant accolades and recognition in the scientific community. Researchers involved in this project have been awarded prestigious grants and honors for their innovative contributions to probiotic delivery systems. Notable achievements include:

  • Best Research Paper Award: The research paper detailing the novel formulation received the best research paper award at several international microbiology and biotechnology conferences.
  • Patent Grants: Multiple patents have been granted for the unique encapsulation techniques and formulations developed during the course of this research.
  • Industry Collaborations: Leading biotechnology and pharmaceutical companies have recognized the potential of this technology and established collaborations to commercialize the probiotic delivery systems.

🌍Impact and Influence :

The impact and influence of this research extend beyond academic circles, affecting various sectors including healthcare, nutrition, and the food industry. The novel non-digestible carbohydrate formulation has revolutionized probiotic delivery, leading to:

  • Improved Gut Health: The enhanced delivery system ensures that Bacillus clausii effectively colonizes the gut, contributing to improved digestive health, immune function, and overall well-being.
  • Commercial Products: Several probiotic supplements and functional foods incorporating this technology have been successfully launched in the market, providing consumers with more effective probiotic solutions.
  • Research Advancements: The success of this research has inspired further studies into microencapsulation and controlled release technologies for other probiotic strains and bioactive compounds.

🌟Legacy and Future Contributions :

The legacy of this research lies in its transformative approach to probiotic delivery, setting a new standard for efficacy and stability in the field. Future contributions are poised to expand on this foundation, exploring:

  • Personalized Probiotic Therapies: Tailoring probiotic formulations to individual microbiome profiles for personalized health benefits.
  • Multi-Strain Encapsulation: Developing encapsulation techniques for multiple probiotic strains to create synergistic effects and enhance gut health.

🎓Publication 

Food waste leachate valorization for sustainable biomass production from Arthrospira maxima

Microencapsulation and controlled release of Bacillus clausii through a novel non-digestible carbohydrate formulation as revolutionizing probiotic delivery

    • Authors :Ramirez-Olea, H., Herrera-Cruz, S., Chavez-Santoscoy, R.A.
    • Journal   :Heliyon
    • Year       : 2024

Microencapsulation and controlled release of Bacillus clausii through a novel non-digestible carbohydrate formulation as revolutionizing probiotic delivery

  • Authors  :Ramirez-Olea, H., Herrera-Cruz, S., Chavez-Santoscoy, R.A.
  • Journal    :Heliyon
  • Year         :  2024

Synthesis and evaluation of Maillard conjugates for encapsulation and controlled delivery of quercetin under simulated gastrointestinal tract conditions

 

Essential-Oils-Loaded Biopolymeric Nanoparticles as Strategies for Microbial and Biofilm Control: A Current Status

Prof Dr. ASHOK KUMAR SHAKYA |Drug Discovery and Development| Best Researcher Award-1226

Prof Dr. ASHOK KUMAR SHAKYA ,Drug Discovery and Development ,Best Researcher Award

Prof Dr. ASHOK KUMAR SHAKYA, at AL-AHLIYYA AMMAN UNIVERSITY ,Jordan

 Profile

Google scholar

    

🎓Early Academic Pursuits

Prof. Dr. Ashok K. Shakya’s academic journey began at Dr. Harisingh Gour University, Sagar (A Central University), India. He earned his Bachelor of Science in 1986, followed by a Master of Pharm. Science in 1988. His academic excellence continued as he pursued a Ph.D. in Pharmaceutical Sciences, which he completed in 1992. His doctoral research focused on the “Synthesis and Pharmacological Evaluation of Some 1:3:4 Thiadiazole Derivatives,” where he synthesized various thiadiazole derivatives and evaluated their pharmacological activities, including CNS depressant, anti-inflammatory, hypotensive, and diuretic effects.

Professional Endeavors

Dr. Shakya’s professional career spans over three decades, marked by significant contributions to pharmaceutical education and research. He began his teaching career as an Assistant Professor at Dr. Harisingh Gour University in 1988. He later held positions at Integral University, Lucknow, India, where he served as the Head of the Faculty of Pharmacy and contributed to establishing Master’s and Ph.D. programs.

In 1995, Dr. Shakya joined Ranbaxy Research Laboratories as a Manager in the Division of Clinical Pharmacology, Pharmacokinetics & Drug Metabolism. Here, he developed and validated various analytical methods for new and existing drug molecules, playing a crucial role in clinical studies (PK/BE/BA).

Since 2008, Dr. Shakya has been associated with Al-Ahliyya Amman University, Jordan. He served as an Assistant Professor, Associate Professor, and currently as a Professor in the Faculty of Pharmacy. He has been instrumental in teaching, research, and curriculum development. His administrative roles include Vice Dean of University Scientific Research and Assistant Dean of PDRC, where he established state-of-the-art research facilities and promoted research collaborations.

Contributions and Research Focus

Dr. Shakya’s research expertise encompasses Medicinal Chemistry, Pharmaceutical Analysis, Phytopharmaceuticals, Formulation Development, and Peptide Synthesis. He has developed several analytical and bioanalytical techniques for new chemical entities (NCE), investigational new drugs (IND), and abbreviated new drug applications (ANDA). His contributions include establishing GLP-compliant animal houses and staying abreast of current trends in cGMP, cGCP, and Good Laboratory Practices.

Dr. Shakya has filed two patents on anticancer and antitubercular agents. His skills extend to various analytical techniques, including LCMSMS, GC-MSMS, UPLC, and molecular modeling. He has also synthesized peptides and peptidomimetics, contributing to the field of drug design and discovery.

Accolades and Recognition

Dr. Shakya’s work has been recognized at numerous international conferences. He has presented his research at prestigious events such as the Eurasia Pharmacy Conference in Turkey, the International Conference on New Trends in Chemometrics and Applications in Turkey, and the Propolis-Human and Bee Health Conference in Bulgaria. His keynote address at the Best Med Grape conference in Beirut, Lebanon, highlights his standing in the scientific community.

Impact and Influence

As an educator and mentor, Dr. Shakya has guided over 70 master’s students, enhancing their research skills and helping them achieve their academic goals. His influence extends beyond teaching, as he has been involved in grant proposal writing, technical report authoring, and the procurement of sophisticated scientific equipment.

Dr. Shakya’s administrative roles have significantly impacted the research environment at Al-Ahliyya Amman University. He has promoted a culture of continuous quality management, encouraging faculty to publish in high-impact journals and facilitating research collaborations. His efforts have contributed to the university’s improved QS ranking and scientific reputation.

Legacy and Future Contributions

Dr. Shakya’s legacy lies in his unwavering commitment to advancing pharmaceutical sciences. His work in developing new analytical methods, synthesizing bioactive compounds, and mentoring future scientists has left an indelible mark on the field. As he continues his academic and research endeavors, Dr. Shakya remains dedicated to pushing the boundaries of pharmaceutical research and education.

🎓Publication 

Antioxidant activity of some common plants

  • Authors   :Nooman A Khalaf, Ashok K Shakya, A. Al-Othman, Zaha El-Agbar
  • Journal    :Turk J. Biol.
  • Year         : 2008

Orotransmucosal drug delivery systems: a review

    • Authors :NV Satheesh Madhav, Ashok K Shakya, Pragati Shakya, Kuldeep Singh
    • Journal   :Journal of controlled release
    • Year       : 2009

Palatal mucosa as a route for systemic drug delivery: A review

  • Authors  :Pragati Shakya, NV Satheesh Madhav, Ashok K Shakya, Kuldeep Singh
  • Journal    :Journal of controlled release
  • Year         :  2011

Fatty acids analysis, antioxidant and biological activity of fixed oil of Annona muricata L. seeds

  • Authors  :Z. Elagbar, R.R. Naik, Ashok K. Shakya, Sanaa K. Bardaweel
  • Journal   :Journal of Chemistry
  • Year        :   2016

 

Estimation of gallic acid, rutin and quercetin in Terminalia chebula by HPTLC

  • Authors  :Ashok Kumar, K Lakshman, KN Jayaveera, S Mani Tripathi, KV Satish
  • Journal   : Jordan J Pharm Sci
  • Year        :   2010