Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Assist. Prof. Dr. Saikat Chaudhuri at CSIR-Central Leather Research Institute, India.

Assist. Prof. Dr. Saikat Chaudhuri is an accomplished organic chemist specializing in natural product synthesis and green chemistry. 🎓 He earned his Ph.D. from IISER Bhopal, focusing on Clavine alkaloids, and holds degrees from Visva Bharati and Burdwan Universities. 🏅 He is a recipient of the Young Scientist Award (2024) and prestigious UGC fellowships. At CSIR-CLRI, he teaches and mentors students across disciplines, guiding numerous projects and theses. 📚 His innovative research, backed by major grants, has led to impactful publications in synthesis and catalysis. đŸ§Ș His work fuels advancements in affordable pharmaceutical chemistry and sustainable methodologies.

Publication Profile 

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Education

Assist. Prof. Dr. Saikat Chaudhuri holds an impressive academic background in organic chemistry. He completed his Ph.D. in Organic Chemistry from IISER Bhopal (2013–2017) under the mentorship of Prof. Alakesh Bisai, focusing on the total syntheses of naturally occurring Clavine alkaloids đŸ§Ș. Prior to this, he earned his M.Sc. in Organic Chemistry from Visva Bharati University (2010–2012) 📘 and a B.Sc. (Hons.) in Chemistry from Burdwan University (2007–2010) 🔬. His strong academic foundation laid the groundwork for his research excellence and innovative contributions to synthetic organic chemistry and drug development.

Awards

Assist. Prof. Dr. Saikat Chaudhuri has been recognized with several prestigious honors throughout his academic journey. In 2024, he received the Young Scientist Award from the CRS Society, Vidyasagar University 🌟. Earlier, he was awarded the esteemed Dr. D.S. Kothari Postdoctoral Fellowship (2019–2021) by UGC, Government of India đŸ§Ș. During his doctoral research, he was a recipient of both Junior Research Fellowship (JRF) and Senior Research Fellowship (SRF) from UGC-NET (2013–2017) 📚. His early promise was evident when he earned the Swami Vivekananda Merit-cum-Means Scholarship (2011–2012) from the Govt. of West Bengal.

Research Focus 

Assist. Prof. Dr. Saikat Chaudhuri is a rising expert in synthetic organic chemistry and medicinal chemistry. His research focuses on the development of novel synthetic methodologies đŸ§Ș for constructing complex heterocycles, such as indoles, benzazepinoindoles, and spiro compounds đŸŒ±. These molecules show promising biological activity, including antibacterial and antifungal properties 💊🩠. He also explores green chemistry approaches, metal-free catalysis, and the total synthesis of natural products 🌍. His work significantly contributes to drug discovery and design, making him a valuable contributor to pharmaceutical research and sustainable chemistry.

Publication Top Notes

  • Synthesis of Dihydro‐benzazepinoindoles via an Oxidative Pictet–Spengler Reaction
  • A New Homogeneous Catalyst for the Synthesis of 3,3â€Č‐Bis(indolyl)methanes: Collective Synthesis of Arundine, Turbomycin B, Arsindoline A, and Tris(1H‐Indol‐3‐yl)methane*
  • A Transition Metal‐Free Strategy for Dihydrobenzazepinoindole via KI‐Mediated Oxidative Pictet–Spengler Reaction
  • Pentafluorophenol‐Catalyzed Metal‐Free Fischer Indole Synthesis: A Novel Approach to Carbazole Derivatives and Desbromoarborescidine A*
  • Water Mediated Chemoselective Synthesis of Novel Spiro Benzoxazinoindoline and Extended Synthesis of Spiro Benzoxazinoindene Derivatives*
  • A Practical and Metal‐Free Approach Towards Synthesis of Spiro‐Benzazepinoindole Derivatives via Pentafluorophenol Catalyzed Pictet‐Spengler Reaction**
  • Efficient, One‐Pot, Green Syntheses of Analogues of 3,4‐Dihydro‐2H Pyrroles as Potential New Antifungal and Antibacterial Agents.
  • A convenient proline catalysed Paal–Knorr synthesis of highly substituted pyrrole: construction of a pyrrolo[2,1-a]isoquinoline scaffold
  • Syntheses of Novel Spirobenzazepinoindole Derivatives via Lewis‐Acid Catalyzed Pictet‐Spengler Cyclization
  • Self-Healable Hydrogels from Vegetable Oil: Preparation, Mechanism, and Applications
  • A Comprehensive Review of Synthetic Approaches Toward Lamellarin D and its Analogous
  • Catalytic Asymmetric Approach to the Naturally Occurring Clavine Alkaloid, (+)-Lysergine
  • Harnessing leather waste in polymer matrix for sustainable smart <scp>shape‐stable</scp> phase change materials
  • Green synthetic approaches for medium ring-sized heterocycles of biological and pharmaceutical interest

Wei Chen | Pharmacology | Best Researcher Award

Wei Chen | Pharmacology | Best Researcher Award

Prof. Wei Chen, Fudan University, China

Prof. Wei Chen is an Associate Professor at Fudan University, specializing in neuroscience and pharmacology. He earned his Ph.D. in Pharmacy from Fudan University and completed postdoctoral research at Stanford University. His work focuses on neuroregeneration, metabolic reprogramming, and precision medicine, with numerous high-impact publications in Nature Communications, Phytomedicine, and Advanced Biology. Prof. Chen has received multiple prestigious awards, including the National Scholarship and the Excellence Award at the International Forum of Precision Medicine. His innovative contributions span both basic research and clinical applications in neuropharmacology and renal therapy.

Publication Profile

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Education

Prof. Wei Chen 🧠💊 is an esteemed Associate Professor at Fudan University, Shanghai, China, serving since September 2022. Prior to this, he was a Postdoctoral Scholar in Neuroscience at Stanford University, Palo Alto, USA (2019–2022), where he advanced cutting-edge research in brain science. Prof. Chen earned his Ph.D. in Pharmacy from Fudan University in 2019, following his M.D. in Pharmacy from the Second Military Medical University (2016) and Anhui Medical University (2013). With a solid foundation in pharmaceutical sciences and neuroscience, his academic journey reflects a commitment to innovation, discovery, and excellence in health research and education 🌍📚.

Awards

Prof. Wei Chen 🏅🎓 has been recognized with numerous prestigious awards and fellowships throughout his academic journey. In 2019, he was honored as one of the Excellent Graduates in Shanghai and received the “Warm Heart” Scholarship 💖. He earned the esteemed National Scholarship twice, in both 2018 and 2017, acknowledging his outstanding academic performance 📘. He also received the Excellence Award at the 2017 International Academic and Industrial Forum of Precision Medicine 🧬. Earlier, he was awarded the Best Student Award in 2016 đŸ„‡ and secured third prize in the Million College Students Science Entrepreneurship Competition in Anhui Province in 2012 💡🏆.

Research Focus

Wei Chen is a prominent researcher with a diverse focus on biomedicine, molecular therapy, and gene therapy. His work primarily explores the treatment of neurodegenerative disorders, kidney injury, liver disease, and cancer. He specializes in immune modulation, particularly through interleukin-22 (IL-22), and metabolic reprogramming to treat various diseases. His research also delves into neuroprotection, cellular regeneration, and inflammatory responses, utilizing innovative approaches like gene delivery and nanoparticle therapy. His contributions aim to transform therapeutic strategies, especially in complex conditions like pancreatic cancer and neurodegeneration.

Publication Top Notes

Qingyihuaji Formula reprograms metabolism to suppress pancreatic cancer growth and progression through LINC00346-OMA1-ATF4 signaling

Notoginsenoside Fc, a novel renoprotective agent, ameliorates glomerular endothelial cells pyroptosis and mitochondrial dysfunction in diabetic nephropathy through regulating HMGCS2 pathway

Maprotiline restores ER homeostasis and rescues neurodegeneration via Histamine Receptor H1 inhibition in retinal ganglion cells

The role of interleukin-22 in lung health and its therapeutic potential for COVID-19.

VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses

Interleukin-22 mediated renal metabolic reprogramming via PFKFB3 to treat kidney injury
Interleukin-22 ameliorated acetaminophen-induced kidney injury by inhibiting mitochondrial dysfunction and inflammatory responses
Gene therapy for neurodegenerative disorders: advances, insights and prospects

Assoc Prof Dr. Fatemeh Moradian| Drug Discovery and Development |Best Researcher Award

Assoc Prof Dr. Fatemeh Moradian|Drug Discovery and Development|Best Researcher Award

Assoc Prof Dr. Fatemeh Moradian at Sari Agricultural Sciences and Natural Resources University,Iran

PROFILE  

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Early Academic Pursuits 🎓

Fatemeh (Elham) Moradian began her academic journey with a B.Sc. in Biology from the University of Shiraz in 1996. Her passion for biochemistry soon led her to pursue further studies at Tarbiat Modares University, where she earned both her M.Sc. in Biochemistry in 2000 and a Ph.D. in Biochemistry in 2006. Her doctoral research, with its focus on enzymology and the intricate biochemical mechanisms involved in living organisms, set the stage for a prolific academic and research career. During this time, she developed expertise in protein structure and function, which later became a cornerstone of her research.

Professional Endeavors đŸ’Œ

Following the completion of her Ph.D., Dr. Moradian joined Sari Agricultural Sciences and Natural Resources University (SANRU), where she has been a faculty member from 2006 to 2019. Throughout her tenure, she has taught several advanced courses, including Biochemistry, Enzymology, Biochemistry Mechanisms of Cancer, Animal Cell Culture, and Bioinformatics. Her teaching approach, known for integrating practical applications and research into the curriculum, has shaped many aspiring scientists and biochemists.
Dr. Moradian also had the opportunity to undertake a sabbatical at the University of Alberta in Canada, where she worked at the prestigious Michael James Lab in the Department of Biochemistry. During this 7-month research period (2005-2006), she contributed to a project focused on the structural genomics of Mycobacterium tuberculosis, honing her expertise in microbial biochemistry and structural analysis.

Contributions and Research Focus 🔬

Dr. Moradian’s research interests span a wide array of biochemistry-related fields, but her core focus lies in enzymology, protein purification, cancer research, and microbial biochemistry. Her research on the isolation, purification, and characterization of novel enzymes has made significant contributions to both environmental and medical biotechnology. One of her early landmark studies involved the isolation and characterization of an alkaline protease from Bacillus sp HS-08, which was presented at the International Conference on Environmental, Industrial, and Applied Microbiology in Spain in 2005.

Her research has taken her across the globe, presenting papers at prestigious international conferences in countries like China, France, the Netherlands, and Russia. Her work on thermostable proteases and their resistance to extreme conditions has significant implications for industrial biotechnology, especially in detergent and solvent industries.

One of her notable research projects involved studying the inhibitory effects of silver (Ag) and iron (Fe) colloidal nanoparticles on P. aeruginosa and E. coli growth, presented at the 17th International Conference on Biotechnology and Nanotechnology in Venice, Italy, in 2015. This work highlights her foray into nanotechnology and its biomedical applications, particularly in developing antimicrobial agents.

Accolades and Recognition 🏅

Throughout her career, Dr. Moradian has gained international recognition for her research contributions. She has been invited to present her work at numerous prestigious conferences, where her findings have been well-received by the global scientific community. Her work on cancer research, particularly the cytotoxic effects of caffeic acid extracted from Echinacea purpurea on human gastric cancer cells, has garnered significant attention. Presented at the International Conference on Medical and Health Sciences in Saint Petersburg, Russia, in 2018, this study underscores her commitment to discovering new avenues for cancer treatment using natural compounds.

Additionally, Dr. Moradian’s research on lactoferrin and its antimicrobial and anticancer effects, which she presented at various conferences in Paris and Indonesia, has positioned her as a key contributor to the field of medical biochemistry, particularly in exploring non-invasive treatments for stomach adenocarcinoma.

Impact and Influence 🌍

Dr. Moradian’s contributions have not only advanced scientific knowledge but have also inspired future generations of scientists. Through her teaching and mentorship, she has guided numerous students toward successful careers in biochemistry and biotechnology. Her integration of theoretical knowledge with real-world applications has been particularly influential in shaping her students’ understanding of the critical role biochemistry plays in solving global challenges, from environmental sustainability to cancer treatment.

Her research on thermostable enzymes and antimicrobial nanoparticles continues to have a broad impact on industries ranging from pharmaceuticals to environmental sciences. Additionally, her work on stress responses in plants, particularly the superoxide dismutase activity in salt stress conditions in Aeluropus littoralis, has implications for agricultural biotechnology and improving crop resilience.

Legacy and Future Contributions đŸŒ±

As an established biochemist with a strong research portfolio, Dr. Moradian’s legacy is already well-established in the fields of enzymology, cancer research, and microbial biochemistry. However, her work is far from over. She continues to explore new frontiers in biochemistry, particularly in the areas of cancer therapeutics and environmental biotechnology. With her vast experience and network of international collaborators, Dr. Moradian is poised to make further groundbreaking contributions to science.
Her future projects are expected to delve deeper into understanding the biochemical mechanisms underlying cancer cell resistance and finding novel ways to target them using natural compounds and engineered nanoparticles.

In summary, Dr. Fatemeh Moradian is a biochemist whose career is marked by innovative research, impactful teaching, and a commitment to scientific discovery. Her work continues to inspire and influence both her peers and the next generation of scientists.

🎓Publication 

In vitro study of the expression of autophagy genes ATG101, mTOR and AMPK in breast cancer with treatment of lactoferrin and in silico study of their communication networks and protein interact

  • Authors   :Atefeh Mashhadi Kholerdi; Fatemeh Moradian; Havva Mehralitabar
  • Journal    :Biophysics and Molecular Biology
  • Year         :2024

Identification, Isolation, Cloning, and Expression of a New Alkaline Serine Protease Gene from Native Iranian Bacillus sp. RAM 53 for Use in the Industry

  • Authors   : Aliakbar Alei; Fatemeh Moradian; Ayoub Farhadi; Mehdi Rostami
  • Journal    :Applied Biochemistry and Biotechnology
  • Year         :2023

Nanoencapsulation of oral‐pharmaceutical lactoferrin using chitosan and the evaluation of stability against trypsin and pepsin and its antibacterial effect

  • Authors   :Ijaz, R., Waqas, M., Mahal, A., Alatawi, N.S., Aloui, Z.
  • Journal    :Journal of Molecular Graphics and Modelling,
  • Year         :2024

Rational designing of phenothiazine dioxide based hole transporting materials for efficient perovskite solar cells

  • Authors   : Farzaneh Hedyeloo; Fatemeh Moradian; Mehran Rostami
  • Journal    :Micro & Nano Letters
  • Year         :2023

The effect of lactoferrin on ULK1 and ATG13 genes expression in breast cancer cell line MCF7 and bioinformatics studies of protein interaction between lactoferrin and the autophagy initiation complex

  • Authors   : Zahra Karabi; Fatemeh Moradian; Mitra Kheirabadi
  • Journal    :Cell Biochemistry and Biophysics
  • Year         :2022

Prof. Rasha Azzam|Drug Discovery and Development|Best Researcher Award

Prof. Rasha Azzam|Drug Discovery and Development |Best Researcher Award

Prof. Rasha Azzam at Helwan University,Egypt

PROFILE  

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Early Academic Pursuits 🎓

Prof. Rasha A. Azzam’s academic journey began with her outstanding performance in chemistry at Helwan University, Egypt, where she graduated with a Bachelor of Science (B.Sc.) in Chemistry in 1993. Her excellence in academia was recognized early on, as she graduated with class honors and was placed on the Dean’s List. Driven by her passion for organic chemistry, she pursued a Master of Science (M.Sc.) degree in Organic Chemistry at Helwan University, completing it in 1996. Her academic curiosity and dedication led her to further her studies internationally, earning a prestigious Ph.D. in Organic Chemistry in 2003 from the Catholic University of Leuven in Belgium. Her diverse educational background laid the foundation for a career defined by groundbreaking research and academic excellence.

Professional Endeavors 🧑‍🔬

Prof. Azzam’s professional career spans over two decades of teaching, research, and leadership in various prestigious academic institutions across the globe. She is currently a Professor of Organic Chemistry at the Faculty of Science, Helwan University, where she has been contributing since 2021. Prior to this, she held the position of Associate Professor of Organic Chemistry at the same institution from 2016 to 2021, demonstrating her upward trajectory in academia.

Her teaching and research influence extended beyond Egypt. She has held positions as an Associate Professor at Taibah University in Saudi Arabia, Nigerian Turkish Nile University in Nigeria, and the American University in Nigeria, where she was a co-founder of the Petroleum Chemistry Program. Additionally, she has served as a Visiting Professor at Virginia Commonwealth University in 2024, further showcasing her international academic reach.

Contributions and Research Focus 🔬

Prof. Azzam’s research focuses on organic and medicinal chemistry, with a particular emphasis on green synthesis, nanomaterials, and antiviral agents. One of her key research interests is the development of new methods for synthesizing compounds with potential anticancer and antimicrobial properties. Her recent project, “Synthesis of new sulfa derivatives under ultrasonic irradiation as potential anticancer/antimicrobial agents,” funded by Helwan University in 2021, highlights her innovative approach to organic synthesis.

Prof. Azzam’s work also explores environmentally friendly technologies, as demonstrated by her research on “green technology based on nanoporous biodegradable polymeric membranes” for wastewater treatment, funded by the Academy of Scientific Research Technology (ASRT). She has also conducted pioneering work on nanomaterials and their applications in industrial processes, such as her research on thermoplastic elastomers based on petrochemicals and the development of anti-COVID-19 agents incorporated into nanofibrous mats.

Her research output is extensive, and she has presented several projects on global platforms, including her work on antiviral therapeutic agents and nanomaterials. Her research contributions are shaping the future of organic chemistry, particularly in the domains of green chemistry and medical applications.

Accolades and Recognition 🏆

Prof. Azzam’s excellence in research and community service has been recognized through numerous awards and honors. In 2023, she received the prestigious Prince Mohammed Bin Fahd Scientific Award for her contributions to scientific production that serves community development within the framework of sustainable development goals. In the same year, she was honored with Helwan University’s Outstanding Scientific Achievement Award in Basic and Applied Sciences.

She has also been recognized for her mentoring and supervision of students, receiving Best Master Thesis Awards for two of her master’s students, Rasha Essam (2020) and Heba Elboshi (2023). Her commitment to advancing research was further acknowledged when she received the Research Excellence Awards for her students, Rokia Ramadan (2019) and Rasha Essam (2020). Additionally, Prof. Azzam was awarded a Silver Medal from the Academy of Scientific Research Technology (ASRT) in 2018 for her outstanding contributions to science.

Her impact extends internationally, with her receiving the Outstanding Faculty Member Award from the American University in Nigeria in 2007, and a research scholarship from the Catholic University of Leuven in 2001.

Impact and Influence 🌍

Prof. Azzam’s influence is felt not only through her research but also through her active participation in the scientific community. She serves as a Review Editor for Organic Chemistry on the Editorial Board of Frontiers in Chemistry and as an editor for the Journal of Chemistry and The Scientific World Journal, both published by Hindawi. She is also a grant evaluator for the Fulbright Binational Scholarship Program, where she helps assess the next generation of academic leaders.

Her commitment to education and community service is reflected in her involvement in organizing training workshops for high school teachers and instructing lab sessions for the AUN Community School. Prof. Azzam is also a member of the Egyptian Society for Basic Sciences, where she contributes to the development of the scientific community in Egypt.

Legacy and Future Contributions 🌟

Prof. Rasha A. Azzam’s legacy is built on her unwavering dedication to advancing organic chemistry, fostering academic excellence, and mentoring the next generation of scientists. Her research has laid the groundwork for significant developments in green chemistry, nanomaterials, and medicinal chemistry. With her continued focus on innovative solutions for pressing global challenges, such as wastewater treatment and the development of antiviral agents, she is poised to make even more impactful contributions in the years to come.

🎓Publication 

In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives

  • Authors   :Toka I. Ismail; Nashwa El-Khazragy; Rasha A. Azzam
  • Journal    :RSC Advances
  • Year         :2024

Novel High-Performance Functionalized and Grafted Bio-Based Chitosan Adsorbents for the Efficient and Selective Removal of Toxic Heavy Metals from Contaminated Water

  • Authors   :Mohammad Monir; Rasha E. Elsayed; Rasha Azzam; Tarek M. Madkour
  • Journal    :Polymers
  • Year         :2024

Crystal structure of 4-(benzo[d]thiazol-2-yl)-1,2-dimethyl-1H-pyrazol-3(2H)-one

  • Authors   :Heba A. Elboshi; Rasha A. Azzam; Galal H. Elgemeie; Peter G. Jones
  • Journal    :Acta Crystallographica Section E Crystallographic Communications
  • Year         :2024

Synthesis of New Guanidine Benzothiazole Derivative and Its Application as Eco-Friendly Corrosion Inhibitor

  • Authors   : Abdel-karim, Amal M.; Azzam, Rasha A.; Shehata, Omnia S.; Adly, Mohamed A.; El-Shamy, Omnia A. A.; El-Mahdy, Gamal A.
  • Journal    :Chemistry
  • Year         :2023

Crystal structure of 2-{[5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazol-3-yl]methyl}benzo[d]thiazole

  • Authors   : Rasha A. Azzam; Galal H. Elgemeie; Heba A. Elboshi; Peter G. Jones
  • Journal    :Crystallographica Section E Crystallographic Communications
  • Year         :2023