Assoc Prof Dr. Fatemeh Moradian|Drug Discovery and Development|Best Researcher Award
Assoc Prof Dr. Fatemeh Moradian at Sari Agricultural Sciences and Natural Resources University,Iran
PROFILE
Early Academic Pursuits 🎓
Fatemeh (Elham) Moradian began her academic journey with a B.Sc. in Biology from the University of Shiraz in 1996. Her passion for biochemistry soon led her to pursue further studies at Tarbiat Modares University, where she earned both her M.Sc. in Biochemistry in 2000 and a Ph.D. in Biochemistry in 2006. Her doctoral research, with its focus on enzymology and the intricate biochemical mechanisms involved in living organisms, set the stage for a prolific academic and research career. During this time, she developed expertise in protein structure and function, which later became a cornerstone of her research.
Professional Endeavors 💼
Following the completion of her Ph.D., Dr. Moradian joined Sari Agricultural Sciences and Natural Resources University (SANRU), where she has been a faculty member from 2006 to 2019. Throughout her tenure, she has taught several advanced courses, including Biochemistry, Enzymology, Biochemistry Mechanisms of Cancer, Animal Cell Culture, and Bioinformatics. Her teaching approach, known for integrating practical applications and research into the curriculum, has shaped many aspiring scientists and biochemists.
Dr. Moradian also had the opportunity to undertake a sabbatical at the University of Alberta in Canada, where she worked at the prestigious Michael James Lab in the Department of Biochemistry. During this 7-month research period (2005-2006), she contributed to a project focused on the structural genomics of Mycobacterium tuberculosis, honing her expertise in microbial biochemistry and structural analysis.
Contributions and Research Focus 🔬
Dr. Moradian’s research interests span a wide array of biochemistry-related fields, but her core focus lies in enzymology, protein purification, cancer research, and microbial biochemistry. Her research on the isolation, purification, and characterization of novel enzymes has made significant contributions to both environmental and medical biotechnology. One of her early landmark studies involved the isolation and characterization of an alkaline protease from Bacillus sp HS-08, which was presented at the International Conference on Environmental, Industrial, and Applied Microbiology in Spain in 2005.
Her research has taken her across the globe, presenting papers at prestigious international conferences in countries like China, France, the Netherlands, and Russia. Her work on thermostable proteases and their resistance to extreme conditions has significant implications for industrial biotechnology, especially in detergent and solvent industries.
One of her notable research projects involved studying the inhibitory effects of silver (Ag) and iron (Fe) colloidal nanoparticles on P. aeruginosa and E. coli growth, presented at the 17th International Conference on Biotechnology and Nanotechnology in Venice, Italy, in 2015. This work highlights her foray into nanotechnology and its biomedical applications, particularly in developing antimicrobial agents.
Accolades and Recognition 🏅
Throughout her career, Dr. Moradian has gained international recognition for her research contributions. She has been invited to present her work at numerous prestigious conferences, where her findings have been well-received by the global scientific community. Her work on cancer research, particularly the cytotoxic effects of caffeic acid extracted from Echinacea purpurea on human gastric cancer cells, has garnered significant attention. Presented at the International Conference on Medical and Health Sciences in Saint Petersburg, Russia, in 2018, this study underscores her commitment to discovering new avenues for cancer treatment using natural compounds.
Additionally, Dr. Moradian’s research on lactoferrin and its antimicrobial and anticancer effects, which she presented at various conferences in Paris and Indonesia, has positioned her as a key contributor to the field of medical biochemistry, particularly in exploring non-invasive treatments for stomach adenocarcinoma.
Impact and Influence 🌍
Dr. Moradian’s contributions have not only advanced scientific knowledge but have also inspired future generations of scientists. Through her teaching and mentorship, she has guided numerous students toward successful careers in biochemistry and biotechnology. Her integration of theoretical knowledge with real-world applications has been particularly influential in shaping her students’ understanding of the critical role biochemistry plays in solving global challenges, from environmental sustainability to cancer treatment.
Her research on thermostable enzymes and antimicrobial nanoparticles continues to have a broad impact on industries ranging from pharmaceuticals to environmental sciences. Additionally, her work on stress responses in plants, particularly the superoxide dismutase activity in salt stress conditions in Aeluropus littoralis, has implications for agricultural biotechnology and improving crop resilience.
Legacy and Future Contributions 🌱
As an established biochemist with a strong research portfolio, Dr. Moradian’s legacy is already well-established in the fields of enzymology, cancer research, and microbial biochemistry. However, her work is far from over. She continues to explore new frontiers in biochemistry, particularly in the areas of cancer therapeutics and environmental biotechnology. With her vast experience and network of international collaborators, Dr. Moradian is poised to make further groundbreaking contributions to science.
Her future projects are expected to delve deeper into understanding the biochemical mechanisms underlying cancer cell resistance and finding novel ways to target them using natural compounds and engineered nanoparticles.
In summary, Dr. Fatemeh Moradian is a biochemist whose career is marked by innovative research, impactful teaching, and a commitment to scientific discovery. Her work continues to inspire and influence both her peers and the next generation of scientists.
🎓Publication
In vitro study of the expression of autophagy genes ATG101, mTOR and AMPK in breast cancer with treatment of lactoferrin and in silico study of their communication networks and protein interact
- Authors :Atefeh Mashhadi Kholerdi; Fatemeh Moradian; Havva Mehralitabar
- Journal :Biophysics and Molecular Biology
- Year :2024
Identification, Isolation, Cloning, and Expression of a New Alkaline Serine Protease Gene from Native Iranian Bacillus sp. RAM 53 for Use in the Industry
- Authors : Aliakbar Alei; Fatemeh Moradian; Ayoub Farhadi; Mehdi Rostami
- Journal :Applied Biochemistry and Biotechnology
- Year :2023
Nanoencapsulation of oral‐pharmaceutical lactoferrin using chitosan and the evaluation of stability against trypsin and pepsin and its antibacterial effect
- Authors :Ijaz, R., Waqas, M., Mahal, A., … Alatawi, N.S., Aloui, Z.
- Journal :Journal of Molecular Graphics and Modelling,
- Year :2024
Rational designing of phenothiazine dioxide based hole transporting materials for efficient perovskite solar cells
- Authors : Farzaneh Hedyeloo; Fatemeh Moradian; Mehran Rostami
- Journal :Micro & Nano Letters
- Year :2023
The effect of lactoferrin on ULK1 and ATG13 genes expression in breast cancer cell line MCF7 and bioinformatics studies of protein interaction between lactoferrin and the autophagy initiation complex
- Authors : Zahra Karabi; Fatemeh Moradian; Mitra Kheirabadi
- Journal :Cell Biochemistry and Biophysics
- Year :2022