Mario Leporace | Personalized Medicine | Best Innovation Award

Mario Leporace | Personalized Medicine | Best Innovation Award

Prof. Dr. Mario Leporace, Hospital and University, Italy

Prof. Dr. Mario Leporace is a distinguished Clinical Radiologist at the Department of Nuclear Medicine and Theragnostics, “Mariano Santo” Hospital, Cosenza, Italy. With expertise in oncologic imaging, hybrid and molecular imaging, and cardiovascular radiology, he is renowned for his advanced diagnostic work using X-ray, CT, MRI, PET/CT, and SPECT/CT. He holds a Master’s in Interventional Oncology and has contributed to over 15 peer-reviewed publications. His professional journey spans top institutions in Rome and Cosenza, marking a career dedicated to innovation in radiology and nuclear medicine.

Publication Profile

Scopus

Education

Prof. Dr. Mario Leporace 🎓 is a distinguished expert in interventional oncology and radiology. In 2022, he earned a Master’s Degree in Interventional Oncology from Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome, with a thesis on thermal ablation of bone metastases 🔥🦴. From 2001 to 2005, he completed his post-graduate certification in Radiology at the University of Rome “Tor Vergata” 🏥, graduating cum laude with a thesis on hybrid imaging 🧠📸. He also obtained his Degree in Medicine and Surgery from the same university (1995–2001), graduating with top honors and a thesis in vascular imaging 🫀🧬.

Experience

Prof. Dr. Mario Leporace 🩺 has an extensive career in radiology and nuclear medicine, showcasing over two decades of dedicated medical service. Since October 2017, he has been serving in the Department of Nuclear Medicine and Theragnostics at “Mariano Santo” Hospital in Cosenza, Italy ⚛️🏥. From May 2016 to September 2017, he worked at the Department of Radiology, “Annunziata” Hospital 🏨. Earlier, from March 2006 to April 2016, he contributed to the European Hospital in Rome, and concurrently, from November 2005 to April 2016, served at the Aurelia Hospital in Rome 🏛️🔬, strengthening his clinical expertise across institutions.

Research Focus

Prof. Dr. Mario Leporace focuses his research on Thermal Ablation with Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) 🔬🧠. His work bridges medical physics and oncological applications, exploring non-invasive treatments that use focused ultrasound energy to thermally ablate tumors with MRI precision guidance 🎯. This technique offers cutting-edge therapeutic possibilities in fields such as oncology, neurology, and women’s health 🧬💡. Prof. Leporace’s contributions advance both the clinical outcomes and technological innovation of MRgFUS, making him a key figure in image-guided therapy, minimally invasive surgery, and cancer treatment research .

Publication Top Notes

The Thermal Ablation with MRgFUS: From Physics to Oncological Applications

SON DINH PHONG | Gene Therapy | Best Researcher Award

SON DINH PHONG | Gene Therapy | Best Researcher Award

Dr SON DINH PHONG, DUYTAN UNIVERSITY, Vietnam

Dr. Dinh Phong Son is a dedicated researcher in molecular medicine at Duy Tan University, Vietnam. With a Ph.D. from Guangxi Medical University, China, and a background in laboratory medicine from Hue University of Medicine and Pharmacy, his research focuses on molecular biomarkers for early disease detection 🧪🔬. He explores the LncRNA/CircRNA/miRNA/gene/protein-drug interaction network and gene-editing techniques like CRISPR/Cas9 for targeted therapy. His work on cardiovascular disease and cancer diagnostics has been published in prestigious journals 📚🧑‍🔬. Passionate about advancing molecular biology, he aspires to contribute to innovative breakthroughs in disease research.

Publication Profile

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Education

Dr. Dinh Phong Son 🎓 holds a degree in Laboratory Medicine Technique from Hue University of Medicine and Pharmacy, Vietnam, and a Ph.D. in Molecular Medicine from Guangxi Medical University, China. 🧬 His expertise lies in molecular biology, with a strong focus on disease biomarkers and gene-targeted therapies. 🏥🔬 With a solid academic foundation, he has contributed significantly to scientific advancements, particularly in precision medicine and diagnostics. His research aims to enhance medical treatments by identifying key genetic markers, paving the way for innovative therapeutic approaches. 🌍✨ Dr. Son’s dedication to science continues to drive breakthroughs in healthcare. 💡👨‍⚕️

Research and Innovations

Dr. Son Dinh Phong 🔬 is deeply engaged in advancing molecular biology through next-generation sequencing and online medical databases. His primary focus is identifying potential biomarkers for early disease detection, including diabetes, cardiovascular diseases, stroke, and cancer. 🧬🩺 His research also explores gene-targeted therapies, utilizing CRISPR/Cas9 for gene editing, overexpression, and silencing. 🏥 His studies on LncRNA/CircRNA/miRNA/gene/protein-drug interaction networks provide a foundation for future medical breakthroughs. 📊✨ Committed to innovation, Dr. Son’s ongoing work (2023-2025) aims to drive scientific progress, hoping for greater support to expand molecular biology research worldwide. 🌍💡

Research Contributions

Dr. Son Dinh Phong 🔬 is highly proficient in advanced molecular biology techniques, including PCR, qPCR, and sequencing analysis 🧪🧬. He specializes in CRISPR/Cas9 genome editing, RNA silencing, and overexpression assays, contributing to groundbreaking gene therapy research. 🏥 His expertise also includes cell culture, western blotting, and fluorescence in situ hybridization, essential for studying gene expression and protein interactions. 🔍🧫 Additionally, he excels in bioinformatics and molecular docking simulations, enabling in-depth analysis of gene interactions and drug responses. 💻💊 With a strong foundation in computational biology, Dr. Son continues to drive innovation in precision medicine and molecular diagnostics. 🚀✨

Editorial Appointments

Dr. Son Dinh Phong 🌍🔬 actively contributes to the global scientific community through his extensive research and publications. While specific editorial roles, consultancy projects, or industry collaborations may not be listed, his scholarly work reflects deep engagement in molecular biology and precision medicine. 🧬📖 His ORCID profile further validates his impactful contributions, showcasing his dedication to advancing medical research. 🏥✨ Through collaborations and scientific discourse, Dr. Son continues to push the boundaries of innovation, striving to enhance disease diagnostics and therapeutic strategies. His commitment to research ensures lasting contributions to the ever-evolving field of molecular medicine. 💡🚀

Research Focus

Dr. Son Dinh Phong’s research primarily focuses on cardiovascular diseases 🫀, non-coding RNAs 🧬, and bioinformatics-driven biomarker discovery 🖥️. His work explores circular RNAs (circRNAs) and microRNAs (miRNAs) in coronary heart disease (CHD) 🏥, revealing their role as competing endogenous RNAs (ceRNAs) in gene regulation. Additionally, he investigates serum miRNAs as potential diagnostic biomarkers for various cancers 🎗️ and employs computational approaches 🔬 to identify key regulatory networks in diseases like latent tuberculosis 🦠. His studies integrate molecular biology, genomics, and systems biology to advance precision medicine 🎯 and therapeutic innovations 💊 for complex diseases.

Publication Top Notes

Assoc Prof Dr. Muhammad Raza| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Razal Kotaska| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Raza at University of Gujrat,Pakistan

PROFILE  

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Early Academic Pursuits 🎓

Dr. Muhammad Asam Raza embarked on his academic journey with a strong foundation in the natural sciences. After completing his F.Sc. from the Board of Intermediate and Secondary Education, Gujranwala in 1998, he pursued a B.Sc. in Zoology, Botany, and Chemistry from the University of Punjab, Lahore. His profound interest in chemistry led him to continue his academic endeavors with an M.Sc. in Chemistry from the same institution, where his research centered on “Production of xylanases and cellulases in bioreactor by using Chaetomium thermophile.”

Dr. Raza’s pursuit of higher education took him to GC University, Lahore, where he earned both his M.Phil. and Ph.D. degrees in Chemistry. His M.Phil. research focused on the “Phytochemical and antioxidant screening of Mimusops elengi,” while his Ph.D. dissertation was centered on the “Extraction, structure elucidation, and microbial transformation of protease inhibitors from medicinal plants.” These early research topics highlight his passion for bioactive compounds and natural product chemistry, setting the stage for a career rich in scientific exploration.

Professional Endeavors 👨‍🏫

Dr. Raza’s academic and research career took off when he joined the University of Gujrat in 2011 as an Assistant Professor in the Department of Chemistry. Over the years, he contributed extensively to teaching and research at the institution, shaping the academic futures of numerous students. His dedication and excellence in the field of chemistry led to his promotion to Associate Professor in December 2020.

In addition to his role as a professor, Dr. Raza has held various administrative responsibilities at the University of Gujrat, including serving as the coordinator of the Four Year Degree Program in Chemistry, time table in-charge, and head examiner for the B.Sc./B.S. Program. His involvement in organizing industrial and study tours has further enriched the academic experiences of students, giving them a practical understanding of their field of study.

Contributions and Research Focus 🔬

Dr. Raza’s research portfolio is vast, focusing primarily on bioactive compounds, their purification, synthesis, and characterization. His expertise in chromatographic techniques, such as Thin Layer Chromatography (TLC), Column Chromatography, and High-Performance Liquid Chromatography (HPLC), has led to significant breakthroughs in the purification of bioactive compounds. He is also proficient in Gas Chromatography-Mass Spectrometry (GC-MS), enabling him to identify volatile compounds and elucidate the structures of synthesized and natural products.

His research interests also encompass microbial transformation, enzyme inhibition, antioxidant studies, and kinetic studies of various reactions. He has explored both natural and synthetic compounds for their antimicrobial and enzyme inhibition properties, significantly contributing to the field of medicinal chemistry. Additionally, Dr. Raza’s work on the production and characterization of xylanases and cellulases from fungal cultures demonstrates his expertise in enzyme technology, which holds potential for industrial applications.

Docking studies, using different software, have also been a significant focus in Dr. Raza’s research. This computational approach to studying molecular interactions has opened new avenues in drug design and development, further enhancing his contributions to the chemistry of biologically active molecules.

Accolades and Recognition 🏆

Throughout his career, Dr. Muhammad Asam Raza has received numerous accolades, reflecting his excellence in both academic and research fields. He was awarded a Merit Scholarship in 1997 from the District Council of Hafizabad, which was an early indicator of his potential. Later, he received the Indigenous PhD 5000 Fellowship Program from the Higher Education Commission (HEC) of Pakistan, a prestigious scholarship that supported his doctoral studies. Dr. Raza’s contributions to research were also acknowledged by the Pakistan Council for Science and Technology (PCST) with Research Productivity Awards in 2012 and 2013.

Further recognition of his expertise came when Dr. Raza was approved as a Ph.D. supervisor by the HEC, allowing him to mentor and guide future researchers in their academic pursuits. Additionally, he secured a research project worth half a million rupees from the HEC, demonstrating his ability to attract significant funding for his research endeavors.

Impact and Influence 🌍

Dr. Raza’s impact extends beyond the classroom and laboratory. His active participation in organizing national and international workshops, seminars, and symposiums has significantly contributed to the dissemination of knowledge in the scientific community. He has been instrumental in hosting events such as the “Two Days Interdisciplinary National Workshop on Chromatography & Mass Spectrometry” and the “Two Days International Symposium on Developments in Contemporary Chemistry” at the University of Gujrat.

His administrative roles have also been influential, particularly his contributions as a member of various departmental committees, including the Departmental Doctoral/MPhil Program Committee (DDMPC) and the Purchase Committee (NRPU). Dr. Raza’s participation in such committees highlights his commitment to improving the academic and research infrastructure at the University of Gujrat.

Furthermore, Dr. Raza’s work as a reviewer for scientific journals and project evaluator for research proposals under the NRPU has contributed to maintaining the standards of scientific inquiry in Pakistan. His expertise is frequently sought in assessing research proposals and reviewing academic papers, ensuring the advancement of chemistry research in the country.

Legacy and Future Contributions 🌱

Dr. Muhammad Asam Raza’s contributions to the field of chemistry, both in terms of research and teaching, have left a lasting legacy at the University of Gujrat and beyond. His commitment to advancing knowledge in bioactive compounds, enzyme inhibition, and molecular docking studies is not only reflected in his research but also in the numerous students he has mentored over the years.

Looking forward, Dr. Raza is poised to continue making significant contributions to the field of chemistry, particularly in the areas of natural product chemistry, enzyme technology, and computational drug design. His future work will likely focus on the synthesis and characterization of biologically active compounds, with potential applications in pharmaceuticals, agriculture, and biotechnology.

Dr. Raza’s legacy will undoubtedly be defined by his passion for chemistry, his dedication to teaching, and his tireless pursuit of scientific excellence, which will continue to inspire future generations of researchers.

🎓Publication 

Acetylcholine and butyrylcholine esterase inhibitory potential of newly synthesized halogenated compounds: In vitro, in silico and MD simulation

  • Authors   : emanur Yesilbağ; Muhammad Asam Raza; Zeshan Ali Sandhu; Umme Farwa; Emine Berrin Poyraz;
  • Journal    :Molecular Structure
  • Year         :2025

Advances in the Optimization of Fe Nanoparticles: Unlocking Antifungal Properties for Biomedical Applications

  • Authors   : Sandhu, Z.A.; Raza, M.A.; Alqurashi, A.; Sajid, S.; Ashraf, S.; Imtiaz, K.; Aman, F.; Alessa, A.H.; Shamsi, M.B.; Latif, M.
  • Journal    :Pharmaceutics
  • Year         :2024

Association of APO B gene polymorphisms with the development of myocardial infarction in Pakistani population

  • Authors   : Arshad, M.; Iqbal, R.; Raza, M.; Bashir, R.; Ahmed, T.; Parveen, A.
  • Journal    :Gene
  • Year         :2024

Beyond graphene: exploring the potential of MXene anodes for enhanced lithium–sulfur battery performance

  • Authors   : Zeshan Ali Sandhu; Kainat Imtiaz; Muhammad Asam Raza; Adnan Ashraf; Areej Tubassum; Sajawal Khan; Umme Farwa; Ali Haider Bhalli; Abdullah G. Al-Sehemi
  • Journal    :RSC Advances
  • Year         :2024

Biomedical properties, characterization of seaweeds species and antimicrobial activity,Propriedades biomédicas, caracterização de espécies de algas marinhas e atividade antimicrobiana

  • Authors   : Rizwan, S.; Saleem, M.; Hassan, H.U.; Raza, M.A.; Kanwal, R.; Kabir, M.; Ghaffar, R.A.; Fadladdin, Y.A.J.; Rafiq, N.; Matin, A. et al.
  • Journal    :Brazilian Journal of Biology
  • Year         :2024

Assoc Prof Dr. Karel Kotaska| Precision Medicine |Best Researcher Award

Assoc Prof Dr. Karel Kotaska|Precision Medicine|Best Researcher Award

Assoc Prof Dr. Karel Kotaska at University Hospital Motol,Czech Republic

PROFILE  

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🎓 Early Academic Pursuits

Kotaška’s academic journey began at the Sladkovského High School in Prague, where he completed his secondary education in 1992. Following this, he embarked on an educational path that laid the foundation for his career in biochemistry. In 1997, he graduated from the Institute of Chemical Technology in Prague, earning a Dipl. Ing. in Chemistry Engineering, specializing in Biomedical Engineering. His thirst for knowledge led him to pursue postgraduate studies at the 2nd Medical Faculty of Charles University, Prague, where he specialized in Biochemistry and Pathobiochemistry, culminating in a Ph.D. in 2003. His doctoral research and thesis defense were pivotal moments in shaping his future career as a leading figure in biochemistry.

🏢 Professional Endeavors

Kotaška’s professional career has spanned over two decades, beginning in 2002 at the Department of Medical Chemistry and Clinical Biochemistry at the University Hospital Motol, one of the largest medical facilities in the Czech Republic. As a research scientist and specialist, he quickly became an integral part of the team, contributing significantly to research projects and clinical laboratory functions. In 2015, Kotaška was appointed Associate Professor in Medical Chemistry and Clinical Biochemistry at the 2nd Medical Faculty of Charles University, further solidifying his standing as an expert in his field. His role expanded into quality management, becoming an auditor and overseeing laboratory processes to ensure adherence to ISO standards and good laboratory practices.

🔬 Contributions and Research Focus

Kotaška’s research interests are broad and impactful, covering various aspects of biochemistry and clinical diagnostics. His primary research focuses on the role of natriuretic peptides in cardiovascular diseases, a field critical for advancing the understanding and treatment of heart-related conditions. He has also made significant strides in investigating biomarkers associated with cardiovascular, neurological, inflammatory, and tumor diseases.

In addition to his contributions to molecular genetics, where he has explored genetic variants linked to diseases, Kotaška is well-versed in laboratory management and external quality control. He has been involved in the harmonization and standardization of laboratory practices, ensuring that diagnostics adhere to global standards. His work in urinalysis and infrared spectroscopy has also pushed forward diagnostic capabilities in clinical biochemistry.

🏆 Accolades and Recognition

Kotaška’s impressive career has not gone unnoticed. He has received numerous grant awards for his research, including projects funded by the Grant Agency of the Ministry of Health (MH) and Charles University. His studies have ranged from investigating biomarkers for organ failure to exploring the molecular biology of neurofibromatosis and cathepsin B activity in bladder carcinoma.

Notably, his project on the biological behavior of urological malignancies, which involved long-term monitoring of tissue, serum, and urine samples, stands out as a pioneering effort in the field of cancer research. Additionally, his ongoing work since 2021 on the effect of combined treatments in chronic heart failure in animal models has further contributed to advancing therapeutic approaches.

🌍 Impact and Influence

Beyond his laboratory work, Kotaška has made substantial contributions to academia and clinical education. Since 2008, he has been involved in teaching postgraduate students and has served as a lecturer at several institutions, including the Czech Technical University, where he taught biomedical engineering and laboratory techniques until 2023. As a member of the education team in postgraduate doctoral studies, he has mentored countless students, helping shape the next generation of biochemists and medical professionals.

Kotaška’s influence extends to his role as a reviewer for several prestigious biomedical journals, such as the Central European Journal of Biology, Open Heart Journal, and Diagnostics. His expertise in statistical methods, including regression analysis, survival analysis, and data evaluation, has positioned him as a thought leader in clinical diagnostics.

📚 Publications and Peer Review

With 66 peer-reviewed publications and 12 book chapters to his name, Kotaška’s work has been widely recognized and cited in the scientific community. His publications span critical topics in clinical biochemistry, genetic research, and molecular diagnostics. His H-index of 10 reflects the significant impact of his research, with 317 citations from scholars and professionals in related fields. His commitment to advancing clinical diagnostics and biochemistry is evident in his body of work, which continues to inform and guide research in these areas.

🏅 Legacy and Future Contributions

Kotaška’s legacy is rooted in his contributions to clinical biochemistry and medical diagnostics. His work on improving diagnostic efficiency, standardizing laboratory procedures, and exploring biomarkers in diseases has set a benchmark in the medical field. As a corresponding member of prominent international organizations, such as the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and the International Federation of Clinical Chemistry (IFCC), his influence extends beyond the Czech Republic to the global scientific community.

Karel Kotaška’s future contributions are likely to focus on further enhancing diagnostic tools and treatment methods, particularly in the fields of cardiovascular diseases and cancer research. His ongoing work in investigating the effects of innovative therapeutic treatments for chronic heart failure demonstrates his commitment to improving patient outcomes. Additionally, his leadership in laboratory standardization efforts will continue to shape the practices of clinical laboratories worldwide, ensuring that diagnostics remain accurate, efficient, and globally harmonized.

🌟 Conclusion

Karel Kotaška’s career is a testament to his dedication to advancing medical science and education. His multifaceted contributions as a researcher, educator, and laboratory manager have left a lasting impact on the fields of biochemistry and clinical diagnostics. His work continues to influence both the scientific community and clinical practices, ensuring his legacy as a leading figure in medical chemistry and clinical biochemistry for years to come.

🎓Publication 

Polycyanoacrylate (super glue) as bladder concretion in a patient after bilateral inguinal hernioplasty

  • Authors   : Karel Kotaška; Milan Polák; Antonín Brisuda; Richard Průša
  • Journal    : Annals of Clinical Biochemistry
  • Year         :2020