Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Saikat Chaudhuri | Drug Discovery and Development | Best Researcher Award

Assist. Prof. Dr. Saikat Chaudhuri at CSIR-Central Leather Research Institute, India.

Assist. Prof. Dr. Saikat Chaudhuri is an accomplished organic chemist specializing in natural product synthesis and green chemistry. 🎓 He earned his Ph.D. from IISER Bhopal, focusing on Clavine alkaloids, and holds degrees from Visva Bharati and Burdwan Universities. 🏅 He is a recipient of the Young Scientist Award (2024) and prestigious UGC fellowships. At CSIR-CLRI, he teaches and mentors students across disciplines, guiding numerous projects and theses. 📚 His innovative research, backed by major grants, has led to impactful publications in synthesis and catalysis. đŸ§Ș His work fuels advancements in affordable pharmaceutical chemistry and sustainable methodologies.

Publication Profile 

Orcid

Education

Assist. Prof. Dr. Saikat Chaudhuri holds an impressive academic background in organic chemistry. He completed his Ph.D. in Organic Chemistry from IISER Bhopal (2013–2017) under the mentorship of Prof. Alakesh Bisai, focusing on the total syntheses of naturally occurring Clavine alkaloids đŸ§Ș. Prior to this, he earned his M.Sc. in Organic Chemistry from Visva Bharati University (2010–2012) 📘 and a B.Sc. (Hons.) in Chemistry from Burdwan University (2007–2010) 🔬. His strong academic foundation laid the groundwork for his research excellence and innovative contributions to synthetic organic chemistry and drug development.

Awards

Assist. Prof. Dr. Saikat Chaudhuri has been recognized with several prestigious honors throughout his academic journey. In 2024, he received the Young Scientist Award from the CRS Society, Vidyasagar University 🌟. Earlier, he was awarded the esteemed Dr. D.S. Kothari Postdoctoral Fellowship (2019–2021) by UGC, Government of India đŸ§Ș. During his doctoral research, he was a recipient of both Junior Research Fellowship (JRF) and Senior Research Fellowship (SRF) from UGC-NET (2013–2017) 📚. His early promise was evident when he earned the Swami Vivekananda Merit-cum-Means Scholarship (2011–2012) from the Govt. of West Bengal.

Research Focus 

Assist. Prof. Dr. Saikat Chaudhuri is a rising expert in synthetic organic chemistry and medicinal chemistry. His research focuses on the development of novel synthetic methodologies đŸ§Ș for constructing complex heterocycles, such as indoles, benzazepinoindoles, and spiro compounds đŸŒ±. These molecules show promising biological activity, including antibacterial and antifungal properties 💊🩠. He also explores green chemistry approaches, metal-free catalysis, and the total synthesis of natural products 🌍. His work significantly contributes to drug discovery and design, making him a valuable contributor to pharmaceutical research and sustainable chemistry.

Publication Top Notes

  • Synthesis of Dihydro‐benzazepinoindoles via an Oxidative Pictet–Spengler Reaction
  • A New Homogeneous Catalyst for the Synthesis of 3,3â€Č‐Bis(indolyl)methanes: Collective Synthesis of Arundine, Turbomycin B, Arsindoline A, and Tris(1H‐Indol‐3‐yl)methane*
  • A Transition Metal‐Free Strategy for Dihydrobenzazepinoindole via KI‐Mediated Oxidative Pictet–Spengler Reaction
  • Pentafluorophenol‐Catalyzed Metal‐Free Fischer Indole Synthesis: A Novel Approach to Carbazole Derivatives and Desbromoarborescidine A*
  • Water Mediated Chemoselective Synthesis of Novel Spiro Benzoxazinoindoline and Extended Synthesis of Spiro Benzoxazinoindene Derivatives*
  • A Practical and Metal‐Free Approach Towards Synthesis of Spiro‐Benzazepinoindole Derivatives via Pentafluorophenol Catalyzed Pictet‐Spengler Reaction**
  • Efficient, One‐Pot, Green Syntheses of Analogues of 3,4‐Dihydro‐2H Pyrroles as Potential New Antifungal and Antibacterial Agents.
  • A convenient proline catalysed Paal–Knorr synthesis of highly substituted pyrrole: construction of a pyrrolo[2,1-a]isoquinoline scaffold
  • Syntheses of Novel Spirobenzazepinoindole Derivatives via Lewis‐Acid Catalyzed Pictet‐Spengler Cyclization
  • Self-Healable Hydrogels from Vegetable Oil: Preparation, Mechanism, and Applications
  • A Comprehensive Review of Synthetic Approaches Toward Lamellarin D and its Analogous
  • Catalytic Asymmetric Approach to the Naturally Occurring Clavine Alkaloid, (+)-Lysergine
  • Harnessing leather waste in polymer matrix for sustainable smart <scp>shape‐stable</scp> phase change materials
  • Green synthetic approaches for medium ring-sized heterocycles of biological and pharmaceutical interest

Prof Dr. Ronit Sverdlov|Pharmacology|Best Researcher Award

Prof Dr. Ronit Sverdlov|Pharmacology|Best Researcher Award

Prof Dr. Ronit Sverdlov at Maastricht University,Netherlands

PROFILE  

ORCID

Scopus

 

Early Academic Pursuits 🎓

Dr. Ronit Shiri-Sverdlov’s academic journey began with a Master’s degree in Biochemistry and Cellular Biology from Tel-Aviv University in Israel, where she graduated magna cum laude. This period was instrumental in shaping her deep interest in cellular and molecular mechanisms, a theme that would remain central to her later work. Building on her foundational knowledge, she pursued a Ph.D. in Molecular Genetics at Tel-Aviv University’s Sheba Medical Center, under the supervision of Prof. E. Friedman. Her doctoral research, focused on identifying germline mutations in the BRCA1 and BRCA2 genes among high-risk Jewish and Arab populations, underscored her commitment to precision genetics and earned her a magna cum laude distinction upon graduation in 2002.

Professional Endeavors đŸ’Œ

Dr. Shiri-Sverdlov joined Maastricht University’s Department of Molecular Genetics in 2001 as a postdoctoral researcher, working with Prof. M.H. Hofker. Her early postdoctoral work provided the groundwork for her lifelong focus on metabolic health, hepatic inflammation, and cholesterol metabolism. In 2004, she transitioned into a faculty position, first as an Assistant Professor and later, an Associate Professor by 2012. In 2016, she was appointed a Full Professor of Hepatic Inflammation and Metabolic Health, reflecting her leadership and expertise in the field. Dr. Shiri-Sverdlov currently leads a vibrant research team within the Faculty of Health, Medicine, and Life Sciences at Maastricht University, where she oversees projects focusing on liver disease, metabolic health, and inflammation under the NUTRIM School of Nutrition and Translational Research in Metabolism.

Contributions and Research Focus 🔬

Dr. Shiri-Sverdlov’s research centers on understanding and combating liver-related diseases, particularly non-alcoholic steatohepatitis (NASH), through molecular insights into cholesterol trafficking and hepatic inflammation. Her investigations have brought critical attention to lysosomal dysfunction as a biomarker for early NASH detection. This research has garnered substantial support, including a €1 million TKI grant in 2017 and several large fellowships from the Dutch Digestive Foundation and NWO ZonMw. Her work emphasizes the role of cholesterol metabolism in Kupffer cells (liver macrophages) and its impact on inflammatory pathways—a field where her studies continue to yield promising therapeutic insights.

Accolades and Recognition 🏆

Over the years, Dr. Shiri-Sverdlov has earned numerous prestigious awards. Her early career was marked by the VENI, VIDI, and ASPASIA fellowships from NWO ZonMw, which collectively supported her pioneering work in cholesterol metabolism and liver inflammation. She received the Marie Sklodowska-Curie Seal of Excellence in 2018, reflecting her proposal’s high evaluation score. She was also awarded the Education Prize by Maastricht University in 2018 for her leadership in developing the Biomedical Sciences curriculum. Additionally, she has been nominated for multiple awards, reflecting her influence in both research and teaching.

Impact and Influence 🌐

Dr. Shiri-Sverdlov has made a significant impact in the field of hepatic health through her research and mentorship. Her work on hepatic lysosomal biomarkers has been pivotal in early disease detection for NASH, with implications for both clinical practice and drug development. As a member of key grant committees, including the Netherlands Organization for Scientific Research (NWO) and the Novo Nordisk Foundation, she actively shapes the research landscape. Her collaboration with researchers across Europe, including those at the University of Reading and Strasbourg University, has contributed to a robust network of shared knowledge and advances in metabolic health.

Legacy and Future Contributions đŸŒ±

Looking to the future, Dr. Shiri-Sverdlov is committed to advancing the understanding of liver diseases through cutting-edge research. Her work not only contributes to therapeutic advancements in NASH and hepatic inflammation but also inspires the next generation of scientists. Through her teaching roles, she continues to influence and guide students in Biomedical Sciences and Nutrition, instilling in them a commitment to rigorous research. Her legacy is further enriched by her leadership in scientific societies, where she champions innovative approaches to metabolic and hepatic health research.

🎓Publication 

Plasma cathepsin D as an early indicator of alcohol-related liver disease

  • Authors   :Li, M., Houben, T., Bitorina, A.V., Thiele, M., Shiri-Sverdlov, R.
    JHEP Reports,
  • Year         :2024

The Modulatory Effects of Fatty Acids on Cancer Progression

  • Authors   :Westheim, A.J.F., Stoffels, L.M., Dubois, L.J., Shiri-Sverdlov, R., Theys, J.
  • Journal    : Biomedicines
  • Year         :2023

All Roads Lead to Cathepsins: The Role of Cathepsins in Non-Alcoholic Steatohepatitis-Induced Hepatocellular Carcinoma

  • Authors   :van Mourik, H., Li, M., Baumgartner, S., Theys, J., Shiri-Sverdlov, R.
  • Journal    :Biomedicines
  • Year         :2022

Fatty Acids as a Tool to Boost Cancer Immunotherapy Efficacy

  • Authors   : Westheim, A.J.F., Stoffels, L.M., Dubois, L.J., Shiri-Sverdlov, R., Theys, J.
  • Journal    : Frontiers in Nutrition
  • Year         :2022

Serum CathepsinD in pregnancy: Relation with metabolic and inflammatory markers and effects of fish oils and probiotics

  • Authors   : Mokkala, K., Gustafsson, J., Vahlberg, T., Plat, J., Laitinen, K.
  • Journal    :Nutrition, Metabolism and Cardiovascular Diseases
  • Year         :2022

Prof. Rasha Azzam|Drug Discovery and Development|Best Researcher Award

Prof. Rasha Azzam|Drug Discovery and Development |Best Researcher Award

Prof. Rasha Azzam at Helwan University,Egypt

PROFILE  

orcid

Early Academic Pursuits 🎓

Prof. Rasha A. Azzam’s academic journey began with her outstanding performance in chemistry at Helwan University, Egypt, where she graduated with a Bachelor of Science (B.Sc.) in Chemistry in 1993. Her excellence in academia was recognized early on, as she graduated with class honors and was placed on the Dean’s List. Driven by her passion for organic chemistry, she pursued a Master of Science (M.Sc.) degree in Organic Chemistry at Helwan University, completing it in 1996. Her academic curiosity and dedication led her to further her studies internationally, earning a prestigious Ph.D. in Organic Chemistry in 2003 from the Catholic University of Leuven in Belgium. Her diverse educational background laid the foundation for a career defined by groundbreaking research and academic excellence.

Professional Endeavors 🧑‍🔬

Prof. Azzam’s professional career spans over two decades of teaching, research, and leadership in various prestigious academic institutions across the globe. She is currently a Professor of Organic Chemistry at the Faculty of Science, Helwan University, where she has been contributing since 2021. Prior to this, she held the position of Associate Professor of Organic Chemistry at the same institution from 2016 to 2021, demonstrating her upward trajectory in academia.

Her teaching and research influence extended beyond Egypt. She has held positions as an Associate Professor at Taibah University in Saudi Arabia, Nigerian Turkish Nile University in Nigeria, and the American University in Nigeria, where she was a co-founder of the Petroleum Chemistry Program. Additionally, she has served as a Visiting Professor at Virginia Commonwealth University in 2024, further showcasing her international academic reach.

Contributions and Research Focus 🔬

Prof. Azzam’s research focuses on organic and medicinal chemistry, with a particular emphasis on green synthesis, nanomaterials, and antiviral agents. One of her key research interests is the development of new methods for synthesizing compounds with potential anticancer and antimicrobial properties. Her recent project, “Synthesis of new sulfa derivatives under ultrasonic irradiation as potential anticancer/antimicrobial agents,” funded by Helwan University in 2021, highlights her innovative approach to organic synthesis.

Prof. Azzam’s work also explores environmentally friendly technologies, as demonstrated by her research on “green technology based on nanoporous biodegradable polymeric membranes” for wastewater treatment, funded by the Academy of Scientific Research Technology (ASRT). She has also conducted pioneering work on nanomaterials and their applications in industrial processes, such as her research on thermoplastic elastomers based on petrochemicals and the development of anti-COVID-19 agents incorporated into nanofibrous mats.

Her research output is extensive, and she has presented several projects on global platforms, including her work on antiviral therapeutic agents and nanomaterials. Her research contributions are shaping the future of organic chemistry, particularly in the domains of green chemistry and medical applications.

Accolades and Recognition 🏆

Prof. Azzam’s excellence in research and community service has been recognized through numerous awards and honors. In 2023, she received the prestigious Prince Mohammed Bin Fahd Scientific Award for her contributions to scientific production that serves community development within the framework of sustainable development goals. In the same year, she was honored with Helwan University’s Outstanding Scientific Achievement Award in Basic and Applied Sciences.

She has also been recognized for her mentoring and supervision of students, receiving Best Master Thesis Awards for two of her master’s students, Rasha Essam (2020) and Heba Elboshi (2023). Her commitment to advancing research was further acknowledged when she received the Research Excellence Awards for her students, Rokia Ramadan (2019) and Rasha Essam (2020). Additionally, Prof. Azzam was awarded a Silver Medal from the Academy of Scientific Research Technology (ASRT) in 2018 for her outstanding contributions to science.

Her impact extends internationally, with her receiving the Outstanding Faculty Member Award from the American University in Nigeria in 2007, and a research scholarship from the Catholic University of Leuven in 2001.

Impact and Influence 🌍

Prof. Azzam’s influence is felt not only through her research but also through her active participation in the scientific community. She serves as a Review Editor for Organic Chemistry on the Editorial Board of Frontiers in Chemistry and as an editor for the Journal of Chemistry and The Scientific World Journal, both published by Hindawi. She is also a grant evaluator for the Fulbright Binational Scholarship Program, where she helps assess the next generation of academic leaders.

Her commitment to education and community service is reflected in her involvement in organizing training workshops for high school teachers and instructing lab sessions for the AUN Community School. Prof. Azzam is also a member of the Egyptian Society for Basic Sciences, where she contributes to the development of the scientific community in Egypt.

Legacy and Future Contributions 🌟

Prof. Rasha A. Azzam’s legacy is built on her unwavering dedication to advancing organic chemistry, fostering academic excellence, and mentoring the next generation of scientists. Her research has laid the groundwork for significant developments in green chemistry, nanomaterials, and medicinal chemistry. With her continued focus on innovative solutions for pressing global challenges, such as wastewater treatment and the development of antiviral agents, she is poised to make even more impactful contributions in the years to come.

🎓Publication 

In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives

  • Authors   :Toka I. Ismail; Nashwa El-Khazragy; Rasha A. Azzam
  • Journal    :RSC Advances
  • Year         :2024

Novel High-Performance Functionalized and Grafted Bio-Based Chitosan Adsorbents for the Efficient and Selective Removal of Toxic Heavy Metals from Contaminated Water

  • Authors   :Mohammad Monir; Rasha E. Elsayed; Rasha Azzam; Tarek M. Madkour
  • Journal    :Polymers
  • Year         :2024

Crystal structure of 4-(benzo[d]thiazol-2-yl)-1,2-dimethyl-1H-pyrazol-3(2H)-one

  • Authors   :Heba A. Elboshi; Rasha A. Azzam; Galal H. Elgemeie; Peter G. Jones
  • Journal    :Acta Crystallographica Section E Crystallographic Communications
  • Year         :2024

Synthesis of New Guanidine Benzothiazole Derivative and Its Application as Eco-Friendly Corrosion Inhibitor

  • Authors   : Abdel-karim, Amal M.; Azzam, Rasha A.; Shehata, Omnia S.; Adly, Mohamed A.; El-Shamy, Omnia A. A.; El-Mahdy, Gamal A.
  • Journal    :Chemistry
  • Year         :2023

Crystal structure of 2-{[5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazol-3-yl]methyl}benzo[d]thiazole

  • Authors   : Rasha A. Azzam; Galal H. Elgemeie; Heba A. Elboshi; Peter G. Jones
  • Journal    :Crystallographica Section E Crystallographic Communications
  • Year         :2023