Ruby Anto | Drug Discovery and Development | Best Researcher Award

Published on by Top Pharmaceutical

Dr. Ruby Anto | Drug Discovery and Development | Best Researcher Award

Centre of Excellence in Nutraceuticals | India

Dr. Ruby Anto is a distinguished biochemist and cancer researcher with an extensive career dedicated to advancing the fields of molecular oncology, bioimmunotherapy, and nutraceutical science. She currently serves as Chief Scientist at the Centre of Excellence in Nutraceuticals, KSCSTE, Government of Kerala, Thiruvananthapuram, and Honorary Scientist at the Institute of Advanced Virology, Thiruvananthapuram. Over her accomplished career, she has held numerous scientific positions at the Rajiv Gandhi Centre for Biotechnology, progressing from Research Associate to Scientist G, reflecting her consistent contributions and leadership in biomedical research.Dr. Anto earned her PhD in Biochemistry from Amala Cancer Research Centre, Thrissur, following her postgraduate studies in Chemistry and Education. Her multidisciplinary academic background—combining chemistry, biochemistry, and pedagogy—has been central to her innovative approach to cancer biology and molecular medicine. Her early academic achievements and later professional experiences at prestigious institutions such as the M.D. Anderson Cancer Center, Houston, provided a strong foundation for her research on targeted cancer therapies, chemopreventive agents, and the role of natural products in disease modulation.Recognized nationally and internationally for her scientific excellence, Dr. Anto has received several prestigious honors, including the Young National Women Bio-Scientist Award from the Department of Biotechnology, Government of India, and fellowships from the National Academy of Sciences, India, and the Academy of Sciences, Thiruvananthapuram. Her professional journey also includes global training experiences, such as her participation in the Clinical Trials Traineeship Program at INSERM, Paris, which broadened her expertise in translational research and clinical validation of nutraceutical interventions.As a mentor, Dr. Anto has nurtured a generation of young scientists, with her students and postdoctoral fellows earning numerous national and international awards for their work in cancer biology and nutraceutical research. Her leadership has fostered a thriving academic environment focused on the discovery and characterization of bioactive compounds from natural sources with therapeutic potential.Dr. Anto’s scientific publications have advanced understanding in areas such as natural compound-mediated cancer prevention, signaling pathway modulation, and anti-inflammatory mechanisms of nutraceuticals. Through her research, she continues to bridge the gap between basic biochemistry and applied health sciences, promoting nutraceutical innovation as a cornerstone of preventive and personalized medicine. Her lifelong dedication to scientific inquiry and mentorship underscores her status as one of India’s leading voices in biochemistry and nutraceutical research.

Profile: Google Scholar

Featured Publications

Ruby, A. J., Kuttan, G., Babu, K. D., Rajasekharan, K. N., & Kuttan, R. (1995). Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Letters, 94(1), 79–83.

Anto, R. J., Mukhopadhyay, A., Denning, K., & Aggarwal, B. B. (2002). Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis, 23(1), 143–150.

Anto, R. J., Sukumaran, K., Kuttan, G., Rao, M. N. A., Subbaraju, V., & Kuttan, R. (1995). Anticancer and antioxidant activity of synthetic chalcones and related compounds. Cancer Letters, 97(1), 33–37.

Oommen, S., Anto, R. J., Srinivas, G., & Karunagaran, D. (2004). Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells. European Journal of Pharmacology, 485(1–3), 97–103.*

Anto, R. J., Mukhopadhyay, A., Shishodia, S., Gairola, C. G., & Aggarwal, B. B. (2002). Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: Correlation with induction of cyclooxygenase-2. Carcinogenesis, 23(9), 1511–1518.*

Bava, S. V., Puliappadamba, V. T., Deepti, A., Nair, A., Karunagaran, D., & Anto, R. J. (2005). Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-κB and the serine/threonine kinase Akt and is independent of tubulin polymerization. Journal of Biological Chemistry, 280(8), 6301–6308.*

Srinivas, G., Anto, R. J., Srinivas, P., Vidhyalakshmi, S., Senan, V. P., & Karunagaran, D. (2003). Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9. European Journal of Pharmacology, 473(2–3), 117–125.*

Matlou Mokgotho | Drug Discovery and Development | Best Researcher Award

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Prof. Dr. Matlou Mokgotho | Drug Discovery and Development | Best Researcher Award

Lecturer at Sefako Makgatho Health Science University | South Africa

Prof. Dr. Matlou Mokgotho is a distinguished biochemist and academic leader with over two decades of experience in higher education, research, and community development. Currently a Senior Lecturer at Tshwane University of Technology, he has previously served as Professor and Head of Department of Biochemistry at the University of Limpopo. His expertise spans molecular biology, proteomics, bioenergetics, enzymology, and mammalian cell cultures. Beyond academia, Dr. Mokgotho has actively contributed to community health awareness initiatives, youth leadership, and ethical oversight in research and professional bodies. His leadership, research excellence, and dedication to mentorship continue to inspire future scientists in South Africa.

Publication Profile 

Orcid

Education 

Prof. Dr. Matlou Mokgotho holds a Doctor of Philosophy in Biochemistry from the University of Limpopo, conferred. He earned his Master of Science in Biochemistry his Bachelor of Science Honours in Biochemistry  both from the University of the North. He also completed a Bachelor of Science in Biochemistry and Microbiology at the same institution. His academic foundation was laid at Seshigo High School, where he obtained his Senior Certificate. This strong educational background provided him with the knowledge and skills to excel in biochemical sciences and academic leadership.

Experience 

Prof. Dr. Matlou Mokgotho career spans roles from tutor to senior lecturer, professor, and department head. He began lecturing in Biochemistry at the University of the North before joining the University of Limpopo, where he advanced to Professor and Head of Department. His teaching portfolio covers biochemistry, molecular biology, proteomics, cell culture, and bioenergetics. He also served as CEO of Milestevens Development and Properties, showcasing leadership in management. Currently, he is Senior Lecturer at Tshwane University of Technology and a module critical reader at UNISA. His responsibilities include teaching, research coordination, and academic mentorship.

Awards and Honors 

Prof. Dr. Matlou Mokgotho has been recognized for his academic, community, and leadership contributions. He received certificates for AIDS Awareness campaigns and laboratory assistance during his early career, highlighting his dedication to education and health promotion. His leadership in youth and church organizations earned him certificates of moral leadership and community service, while his active role in HIV/AIDS awareness workshops reflected his commitment to social impact. As a council member of the South African Dental Technician Council, he contributed to professional ethics and governance. These accolades underscore his commitment to advancing science, leadership, and community development.

Research Focus 

Prof. Dr. Matlou Mokgotho research focuses on biochemistry, molecular biology, and proteomics, with a special interest in bioenergetics, protein structure-function relationships, and mammalian cell cultures. His work bridges fundamental and applied science, exploring enzymology, molecular mechanisms, and the applications of cell cultures in medical research. He has also contributed to developing experimental methodologies and training students in proposal writing, research principles, and dissertation development. His commitment to advancing biochemistry is reflected in his integration of teaching, research, and community engagement, with a strong emphasis on preparing students for careers in molecular science and addressing health challenges through biotechnological approaches.

Publication Top Notes