Johan Alexander Villada Ramos | Drug Discovery and Development | Best Researcher Award

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Johan Alexander Villada Ramos | Drug Discovery and Development | Best Researcher Award

Prof. Johan Alexander Villada Ramos, Universidad del Quindío, Colombia

Johan Alexander Villada Ramos is a Ph.D. candidate in Sciences at Universidad del Quindío, specializing in natural alternatives to synthetic pesticides 🌱🦠. He holds a Master’s in Biomedical Sciences, earning a meritorious distinction 🏅, and a Biology degree. His research spans bioactive plant compounds, cancer prevention, and lipid metabolism. As a university lecturer 📚, he teaches molecular biology and biochemistry. With multiple research projects, publications, and awards, including the Carlos Corredor Pereira National Award in Biomedical Sciences (2024) 🏆, Johan is a dedicated scientist pushing the boundaries of biotechnology and microbiology.

Publication Profile

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Education

Prof. Johan Alexander Villada Ramos 🎓 is a doctoral student in Sciences at the Universidad del Quindío, focusing on the bioactivity of free and microencapsulated Tagetes erecta L. 🌿 as an alternative to synthetic pesticides against the avocado weevil Heilipus lauri 🥑. He earned a Master’s in Biomedical Sciences (2018–2022) with meritorious distinction 🏅, researching the effects of Passiflora edulis extract on lipid metabolism enzymes in human colorectal adenocarcinoma cells. His Biology degree (2013–2018) involved evaluating the antibacterial activity of Tagetes patula L. against Ralstonia solanacearum. Additionally, he trained in microbiology and biotechnology lab preparation at SENA (2017–2018) 🔬.

Professional Achievements

Prof. Johan Alexander Villada Ramos 🎓 has made significant contributions to biomedical and biological research. He earned a meritorious distinction 🏅 for his master’s research on Passiflora edulis 🍊 and its effects on lipid metabolism in colorectal cancer cells. Holding a Biology degree 🔬, his studies focused on the antimicrobial activity of plant extracts against pathogens. He has been actively involved in high-impact research projects 📚 at prestigious institutions, including Pontificia Universidad Javeriana and Universidad del Quindío. His work continues to advance natural alternatives 🌱 in disease management, reinforcing his dedication to scientific discovery and innovation.

Leadership in Academia

Prof. Johan Alexander Villada Ramos 🎓 is a dedicated academic leader, serving as a lecturer 📖 in molecular biology, biochemistry, and microbiology 🔬 at Universidad del Quindío. Passionate about education, he actively contributes to curriculum development 🏫, ensuring that students receive up-to-date and high-quality training. Additionally, he plays a key role in laboratory training 🧪, equipping future scientists with essential research skills. His commitment to fostering scientific knowledge and practical expertise strengthens the university’s academic foundation, inspiring students to excel in the fields of biotechnology, microbiology, and biomedical sciences. 🚀

Research Focus

Prof. Johan Alexander Villada Ramos specializes in natural product chemistry, biochemistry, and phytopharmacology, with a strong focus on the antioxidant, antibacterial, and anticancer properties of plant extracts. His research explores bioactive compounds from medicinal plants, such as Coffea arabica ☕, Passiflora edulis 🍃, and Tagetes patula 🌼, investigating their effects on oxidative stress, protein oxidation, and bacterial inhibition 🦠. His studies contribute to pharmaceutical development, food science, and biomedicine, aiming to harness plant-derived compounds for disease prevention and therapeutic applications. 🏥

Publication Top Notes

Potencial antioxidante del extracto de hoja de Coffea arabica sobre la lipoperoxidación y oxidación proteica en un modelo de músculo bovino

Identification of potential bioactive compounds of Passiflora edulis leaf extract against colon adenocarcinoma cells

Evaluation of antibacterial activity of extract and essential oil of Tagetes patula L. in vitro against Ralstonia solanacearum biovar 2

Nazia chaudhary | Drug Repurposing | Young Scientist Award

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Nazia chaudhary | Drug Repurposing | Young Scientist Award

Dr Nazia chaudhary, ACTREC, TMC, India

Dr. Nazia Chaudhary is a distinguished cancer researcher 🧬 with a Ph.D. focused on pathways promoting tumorigenesis and therapy resistance upon Plakophilin 3 loss 🎗️. Her academic journey includes notable projects on protease-producing thermophiles 🌡️ and mitochondrial function ⚡. She co-holds patents on Lipocalin-2 antibodies 🧪 and has published extensively in high-impact journals 📚, including Redox Biology and FEBS Letters. A DST Inspire Faculty Fellow (2023) 🌟, she has received numerous awards, including the Vaishno Endowment Prize 🏆 and Mahindra Talent Scholarships 🎓. Dr. Chaudhary’s impactful work has been presented globally 🌍, including at Cold Spring Harbor Laboratory, New York.

Publication Profile

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Academic Project

Dr. Nazia Chaudhary is an accomplished researcher with a Ph.D. focused on the project “Characterization of pathways that promote tumorigenesis, radio, and chemo-resistance upon Plakophilin 3 loss.” 💡🧬 She worked on isolating and characterizing protease and antimicrobial-producing thermophiles from Ganeshpuri hot springs at St. Xavier’s College, Mumbai (Jan-Apr 2015). 🌋🔬 Additionally, she contributed to the external project “MKT1 Dependent Regulation of Mitochondrial Function” at Tata Institute of Fundamental Research (May-Aug 2014). 🧪⚙️ Her EXSP project involved isolating and screening thermophilic Actinomycetes for enzymes with industrial importance. 🔍🌡️ Dr. Chaudhary’s diverse research showcases her expertise in microbiology and biotechnology. 🌟

Conference Attended

Dr. Nazia Chaudhary has showcased her research on various esteemed platforms. She presented a poster titled “Screening of Thermophilic Actinomycetes Capable of Producing Enzymes of Industrial Importance” at the Shri Sajjan Gupta Memorial Trophy for Excellence in Biological Science, held on December 11, 2012, at G.N. Khalsa College. Another poster, “Increase in Lipocalin2 Expression Upon Plakophilin3 Loss Confers Chemo and Radioresistance to Tumor Cells,” was presented at the Environmental Mutagen Society of India (EMSI) conference in January 2018 at BARC, Mumbai, and at the prestigious Mechanisms & Models of Cancer meeting in August 2018 at Cold Spring Harbor Laboratory, New York. 🌟🔬📊

Awards and Honors

Dr. Nazia Chaudhary is a distinguished scholar with multiple accolades. She was awarded the prestigious DST Inspire Faculty Award in 2023 and recognized for her research on lipocalin 2 expression and chemo-radiotherapy resistance at the 14th Indo-Australian Biotechnology Conference. She served as a Board of Studies member for Sophia College’s Zoology Department (2018-2021). Throughout her academic journey, she earned various honors, including the Ramidevi Murlidhar Jalan Award 🏆, Saifee Education Aid Scholarship 🎓, and the Mahindra Search for Talent Scholarship 🌟. Her exceptional performance also earned her the Mrs. A. Varghese Prize 🥇 and several other prestigious scholarships and awards.

Patent

Dr. Nazia Chaudhary, along with Sorab N. Dalal, Manjula Das, Sujan K. Dhar, and Smitha P. K., contributed to the development of “Antibodies Against Lipocalin-2 and Use Thereof.” This groundbreaking research led to two key milestones. The first was the PCT application (PCT/IN2020/051068) with publication no. WO/2021/137254 on July 8, 2021. The second was the Indian patent (DBT Indian Patent no: 202021000274) granted on July 30, 2021, published in the Patent Office journal no. 31/2021. These innovations hold significant potential for medical advancements. 🧬💉🧪🔬

Research Focus

Dr. Nazia Chaudhary’s research focuses on the molecular mechanisms of cancer progression, therapy resistance, and invasion, particularly in triple-negative breast cancer (TNBC) and colorectal cancer. She investigates the role of Lipocalin 2 (LCN2) in regulating cellular processes like focal adhesion formation, actin glutathionylation, and ferroptosis inhibition, which are critical for tumor cell migration and resistance to treatment. Her work explores the interplay between signaling pathways, such as Src activation and glutathione metabolism, to uncover potential vulnerabilities in cancer cells. 🧬💥💉🧪🧫

Publication Top Notes

LCN2 promotes focal adhesion formation and invasion by stimulating Src activation

EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition

Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration.

The Role of Lipocalin 2 (LCN2) in Regulating Ferroptosis and Therapy Resistance

Dr. Marc Bender|Immunotherapy |Best Researcher Award

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Dr. Marc Bender|Pharmaceutical Chemistry |Best Researcher Award|

Dr. Marc Bender at abriz University of Medical Sciences, Iran

PROFILE  

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Early Academic Pursuits 📚

Marc Bender’s academic journey began with a strong foundation in molecular biology, earning a (link unavailable) and (link unavailable) from Universität Hamburg. He furthered his expertise by pursuing a doctorate in skin cancer research at the department of dermatology, Elbe Klinikum Buxtehude. His thesis focused on elucidating molecular mechanisms, particularly epigenetic regulation via miRNAs, involved in tumor progression of cutaneous squamous cell carcinoma.

Professional Endeavors 💼

As a data scientist, Marc contributed to the European melanoma registry (EUMelaReg), evaluating retrospective data for real-world clinical trials. This experience deepened his understanding of melanoma and immunotherapy, and he developed skills in statistical methods and programming. His professional endeavors have been marked by a commitment to advancing cancer research and treatment.

Contributions and Research Focus 🔬

Marc’s research focus encompasses various aspects of skin cancer, including:

– Investigating effects of combined UVA, UVB, visible light, and infrared radiation on human skin cells (KAUVIR)
– Examining the influence of UVA and UVB irradiation on human dermal stem cells (UV-DHDS)
– Comparing treatments for melanoma, including anti-PD1 monotherapy and BRAF/MEK inhibitor treatment (PDSeq and EMRSeq)
– Analyzing immune checkpoint inhibitor maintenance treatment after achieving a partial or complete response (EUMelaReg)

Accolades and Recognition 🏆

Marc’s work has been recognized through publications in esteemed journals, including:

– Journal of Cancer Research and Clinical Oncology
– Journal of Photochemistry and Photobiology B Biology
– Cancers (MDPI)
– Journal of Clinical Oncology (conference paper)
– Annals of Oncology (conference paper)

Impact and Influence 🌟

Marc’s research has contributed significantly to the understanding of skin cancer mechanisms and treatment options. His work has:

– Advanced knowledge of miRNA expression and its association with tumor progression
– Investigated treatment adherence in patients with stage III melanoma
– Compared outcomes of different treatment approaches for metastatic melanoma

Legacy and Future Contributions 🌱

As a dedicated researcher, Marc continues to contribute to the field of skin cancer research. His future endeavors will likely focus on:

– Furthering understanding of molecular mechanisms in skin cancer
– Developing innovative treatment approaches
– Collaborating with international researchers to advance cancer research

Marc’s legacy will be marked by his commitment to advancing cancer research, improving treatment options, and enhancing patient outcomes. His work will continue to influence the scientific community, inspiring future generations of researchers.

🎓Publication 

Real-World Therapy with Pembrolizumab: Outcomes and Surrogate Endpoints for Predicting Survival in Advanced Melanoma Patients in Germany

  • Authors   : Marc Bender
  • Journal    :Cancers
  • Year         :2022

UVB damage response of dermal stem cells as melanocyte precursors compared to keratinocytes, melanocytes, and fibroblasts from human foreskin

  • Authors   :Marc Bender
  • Journal    :Photochemistry and Photobiology B: Biology
  • Year         :2021

UV-type specific alteration of miRNA expression and its association with tumor progression and metastasis in SCC cell lines

  • Authors   : Marc Bender
  • Journal    :Cancer Research and Clinical Oncologyy
  • Year         :2020

 

Dr. David Chukwu Obas| Medical Biochemistry and Toxicology|Outstanding Scientist Award

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Dr. David Chukwu Obas, Medical Biochemistry and Toxicology,Outstanding Scientist Award

Dr. David Chukwu Obas, at International Institute for Toxicology,Nigeria

PROFILE

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🎓Early Academic Pursuits :

Dr. David Chukwu Obasi was born on May 10, 1985, in Abakaliki, Ebonyi State, Nigeria. His academic journey began at Umuka Community Primary School in Okposi, where he laid the foundation for his educational aspirations. He continued his studies at Government Secondary School Okposi, where he completed his West African School Certificate (WASC) in 2002. Dr. Obasi pursued a Bachelor of Science degree in Biochemistry at Anambra State University, graduating in 2009. His quest for knowledge propelled him further into academia, where he earned a Master of Science in Medical Biochemistry from Ebonyi State University in 2015. His dedication culminated in a Ph.D. in Medical Biochemistry from the University of Nigeria, Nsukka, in 2020. Throughout these formative years, Dr. Obasi developed a robust understanding of biochemistry, preparing him for his future endeavors in research and academia.

💼Professional Endeavors :

Dr. Obasi’s professional journey is marked by a series of significant academic positions, reflecting his expertise in medical biochemistry. He began his career as a Graduate Assistant at Evangel University, Akaeze, Ebonyi State, where he honed his teaching skills from 2012 to 2015. His dedication and academic prowess led to progressive promotions, first to Assistant Lecturer, then Lecturer II, and subsequently Lecturer I at Evangel University until 2022. In 2022, he took on the role of Senior Lecturer at David Umahi Federal University of Health Sciences in Uburu, Ebonyi State. Dr. Obasi’s academic leadership has been recognized through his appointment as the Acting Head of the Medical Biochemistry Department, where he influences the curriculum and research initiatives.

🔬Contributions and Research Focus :

Dr. Obasi’s research primarily focuses on the biochemical aspects of health and disease, with a special emphasis on toxicity and antioxidant effects of various substances. His contributions to the field are exemplified by his presentations at prestigious conferences, where he shared groundbreaking findings. Notable among these was his paper on the toxicity of aqueous stem-bark extract of Albizia chevalieri on juvenile African catfish, presented at the 13th South East Zonal Conference of the Nigerian Society of Biochemistry and Molecular Biology. He has also explored the bioactive constituents and antioxidant properties of herbal remedies, reflecting a commitment to understanding natural compounds’ roles in health.

His ability to review scholarly articles for reputable journals, such as the Nigerian Journal of Biochemistry and Molecular Biology and Scientific African, further underscores his dedication to advancing scientific knowledge.

🏆Accolades and Recognition :

Throughout his career, Dr. Obasi has received various accolades for his contributions to the field of medical biochemistry. His research and presentations at national conferences have garnered attention, enhancing his reputation among peers and establishing him as a thought leader in his area of expertise. The recognition he has received not only highlights his academic achievements but also his role in advancing the field of biochemistry in Nigeria.

🌍Impact and Influence :

Dr. Obasi’s influence extends beyond his research and teaching. As a dedicated educator, he plays a pivotal role in shaping the next generation of biochemists. His responsibilities include advising students, supervising seminars and projects, and fostering an environment of inquiry and innovation. His leadership roles, including his position as the Acting Head of the Medical Biochemistry Department, allow him to impact curriculum development and departmental strategies. Furthermore, his active membership in professional organizations like the Nigerian Society of Biochemistry and Molecular Biology and the Society of Toxicology showcases his commitment to collaboration and professional development within the scientific community.

🔮Legacy and Future Contributions :

Dr. David C. Obasi’s legacy is characterized by his contributions to medical biochemistry and his role as a mentor and leader in academia. His commitment to research and teaching has laid a foundation for future generations of biochemists. As he continues to explore the biochemical implications of natural products and their potential therapeutic effects, Dr. Obasi aims to contribute significantly to the scientific community. His vision for future research includes exploring innovative solutions to health challenges faced by his community and beyond. Through ongoing collaboration with fellow researchers and institutions, he aspires to further elevate the standards of biochemistry education and research in Nigeria.

🎓Publication 

Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine

  • Authors   :Egwu, C.O., Aloke, C., Onwe, K.T., … Obasi, D.C., Okoro, C.O.
  • Journal    :Molecules
  • Year         :2024

Effect of Ruzu Herbal Bitters on the Liver Function and Lipid Profile Parameters of Alloxan-Induced Diabetic Rats

GC-MS analysis, pH and antioxidant effect of Ruzu herbal bitters on alloxan-induced diabetic rats