Xia Xiao | Pharmacodynamics | Best Researcher Award

Xia Xiao | Pharmacodynamics | Best Researcher Award

Assoc. Prof. Dr. Xia Xiao, Yangzhou University, China

Assoc. Prof. Dr. Xia Xiao is a distinguished researcher in veterinary microbiology at Yangzhou University. He earned his Ph.D. in Veterinary Science from South China Agricultural University (2015) 🎓, specializing in bacteriophage-mediated antibiotic resistance. His research focuses on antimicrobial pharmacokinetics, novel antimicrobial agents, and bacterial resistance mechanisms 🦠💊. A former visiting scholar at UCLA (2018-2019), Dr. Xiao has published extensively in high-impact journals 📚. His work contributes to the rational use of antibiotics and combating multidrug resistance, advancing veterinary and human medicine alike. 🏆🔍

Publication Profile

Scopus

Education

Assoc. Prof. Dr. Xia Xiao is a leading veterinary microbiologist at Yangzhou University. He earned his Ph.D. in Veterinary Science from South China Agricultural University (2015) 🎓, specializing in bacteriophage-mediated antibiotic resistance. As a former visiting scholar at UCLA (2018-2019) 🌍, his research focuses on antimicrobial pharmacokinetics, novel antimicrobial agents, and bacterial resistance mechanisms 🦠💊. Since 2020, he has been an Associate Professor, contributing to advancements in antibiotic utilization and resistance control. His work plays a crucial role in improving both veterinary and human medicine. 📚

Experience

Assoc. Prof. Dr. Xia Xiao is a veterinary microbiologist at Yangzhou University, specializing in antimicrobial resistance 🦠💊. He earned his Ph.D. from South China Agricultural University (2015) 🎓, focusing on bacteriophage-mediated antibiotic resistance. As a Visiting Scholar at UCLA (2018-2019) 🌍, he expanded his research through international collaborations, enhancing his contributions to the global scientific community 🔬🤝. His work explores antibiotic pharmacokinetics, novel antimicrobial agents, and bacterial resistance strategies. Since 2020, he has been an Associate Professor, making impactful strides in veterinary and human medicine. 📚🏆

Focus Areas

Assoc. Prof. Dr. Xia Xiao is a veterinary microbiologist at Yangzhou University, specializing in antimicrobial resistance and antibiotic optimization 💊📊. He earned his Ph.D. from South China Agricultural University (2015) 🎓 and later expanded his research through international collaboration as a Visiting Scholar at UCLA (2018-2019) 🌍. His work focuses on pharmacokinetics-based antibiotic use, novel antimicrobial development, and strategies to combat bacterial resistance 🏥⚕️. His groundbreaking research on bacteriophage-mediated resistance transmission addresses global health challenges, making significant contributions to veterinary and medical microbiology. 📚🏆

Research Focus

Assoc. Prof. Dr. Xia Xiao’s research primarily focuses on antimicrobial resistance (AMR) 🦠💊, pharmacokinetics/pharmacodynamics (PK/PD) modeling 📊🧪, and bacterial resistance mechanisms 🔬🧫. Her work explores the role of resistance genes, such as mcr-1, blaNDM-5, and tet(X4), in multidrug-resistant pathogens, including Klebsiella pneumoniae and Escherichia coli. She investigates novel strategies to combat AMR, including using natural compounds 🌿, repurposed drugs 💡, and PK/PD-based optimization 📉📈. Her research has significant implications for developing effective treatments against drug-resistant infections in both humans and animals 🏥🐾.

Publication Top Notes

DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr-carrying Bacteria Through a Negative Feedback Regulatory Mechanism

Acetylshikonin Derived From Arnebia euchroma (Royle) Johnst Kills Multidrug-Resistant Gram-Positive Pathogens In Vitro and In Vivo

Acetylshikonin reduces the spread of antibiotic resistance via plasmid conjugation

The Food Additive Benzaldehyde Confers a Broad Antibiotic Tolerance by Modulating Bacterial Metabolism and Inhibiting the Formation of Bacterial Flagella

Gramine sensitizes Klebsiella pneumoniae to tigecycline killing

Characterization of a cfr-bearing integrative and conjugative element in Proteus cibarius coharbouring tet(X6) on the chromosome

Mahshid Malakootian | Cardiovascular Pharmacology | Best Researcher Award

Mahshid Malakootian | Cardiovascular Pharmacology | Best Researcher Award

Assoc. Prof. Dr Mahshid Malakootian, Rajaie cardiovascular medical and research center, Iran

Born on March 21, 1981, in Tehran, Iran, Dr. Mahshid Malakootian is a distinguished molecular geneticist and Associate Professor at Rajaie Cardiovascular Medical & Research Institute, Tehran. A prolific researcher, she specializes in non-coding RNAs, cardiovascular genetics, and bioinformatics. She completed her Ph.D. in Molecular Genetics at Tarbiat Modares University and held postdoctoral fellowships at McGill University and Case Western Reserve University. Dr. Malakootian has published extensively and received numerous accolades, including Best Young Researcher awards. Fluent in English and Persian, she is a dedicated academic, head of the Cardiogenetic Research Center, and an editorial board member. 📚🧬🌍

Publication Profile

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Academic Excellence

Assoc. Prof. Dr. Mahshid Malakootian is a distinguished expert in molecular genetics and cardiogenetics, contributing significantly to the field. Since 2021, she has served as an Associate Professor at the Cardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran, Iran. 💡 From 2018, she has led the center as its Head, advancing groundbreaking research in cardiovascular genetics. 🧬 Previously, she was an Assistant Professor from 2015 to 2021 and has been an active board member of the Research Deputy since 2015, shaping impactful scientific initiatives. 📚 Her work continues to drive innovation in cardiovascular health. ❤️

Research Experience

Assoc. Prof. Dr. Mahshid Malakootian is an accomplished molecular geneticist with extensive research experience. She pursued her post-doctorate in Experimental Medicine at McGill University, Canada (2016-2017), focusing on PCSK7 RNA regulators 🧬. Previously, she was a post-doctoral fellow at Tarbiat Modares University, Tehran (2014-2015), and a visiting research scholar at Case Western Reserve University, USA (2011-2012) 🔬. Dr. Malakootian earned her Ph.D. (2009-2014) and M.Sc. (2004-2007) in Molecular Genetics at Tarbiat Modares University, where she explored non-coding RNAs and tumorigenesis. Her academic journey began with a B.Sc. in Cellular and Molecular Sciences from the University of Tehran (1999-2003) 🧪.

Honors and Awards

Assoc. Prof. Dr. Mahshid Malakootian is an award-winning researcher recognized for her outstanding contributions in molecular genetics and stem cell technology. 🏆 She has earned accolades such as the “Best Young Researcher” award (2017, 2019) and the “Top Thesis Award” (2014). 🎖 Her pioneering research is supported by multiple grants, including studies on noncoding RNAs and cardiovascular biomarkers. She has discovered and sequenced numerous novel genetic variants, published in GenBank, and co-authored a U.S. patent for miR-her2-1, aiding breast and ovarian cancer diagnostics. 💡📚 A scholar of exceptional caliber, Dr. Malakootian remains a trailblazer in biomedical innovation. 🌟

Professional Societies

Assoc. Prof. Dr. Mahshid Malakootian is an accomplished scientist and an active member of prestigious organizations, including the American Association for Cancer Research (AACR) 🌟, the Iranian Genetics Society (IGS) 🧬, and the Iranian Biotechnology Society 🌿. Her dedication to advancing research is reflected in her role as an editorial board member of the Environmental Health Engineering and Management Journal 📚. With her extensive expertise and contributions, she continues to shape the fields of cancer research, genetics, and biotechnology, fostering innovative solutions for global health challenges 🌍. Dr. Malakootian’s work exemplifies excellence and inspires the scientific community. ✨

Teaching Experience

Associate Professor Dr. Mahshid Malakootian is a distinguished expert in molecular genetics at Shahed University, where she also leads the Advanced Molecular Genetics Lab Course 🧬. Her dedication to education and research has inspired countless students and colleagues. Dr. Malakootian has honed her expertise as a research assistant in Dr. Mowla’s laboratory, contributing to cutting-edge discoveries in molecular genetics 🔬. With a passion for advancing knowledge, she has made significant strides in her field, combining academic excellence with hands-on laboratory experience. Her work continues to shape the future of genetic research and education, making her a respected figure in the scientific community.

Research Focus

Assoc. Prof. Dr. Mahshid Malakootian focuses on cutting-edge research in microRNAs, cardiovascular diseases, and non-coding RNAs in various biological and pathological contexts. Her work explores microRNA roles in cardiovascular development, post-transcriptional regulation, and cancer biology, particularly lung and esophageal tumors. Dr. Malakootian also investigates long non-coding RNAs (lncRNAs), circular RNAs, and their interplay in genetic regulation and disease pathways. Her studies on epigenetics and innovative therapeutic approaches significantly impact cardiovascular health and cancer treatment. 🧬🩺🫀

Publication Top Notes

MicroRNAs: roles in cardiovascular development and disease

Post-transcriptional regulation of PCSK9 by miR-191, miR-222, and miR-224

Two lung development-related microRNAs, miR-134 and miR-187, are differentially expressed in lung tumors

Ciprofloxacin removal from aqueous media by adsorption process: a systematic review and meta-analysis

Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review

Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma

Overexpression of BMI1, a polycomb group repressor protein, in bladder tumors: a preliminary report

Differential expression of nucleostemin, a stem cell marker, and its variants in different types of brain tumors

lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells

Roxana Matran | Pharmacology | Best Researcher Award

Roxana Matran | Pharmacology | Best Researcher Award

Assist Prof Dr Roxana Matran, UMF “Carol Davila”, Romania

Dr. Roxana Matran is a distinguished pediatric gastroenterologist and academic with a Ph.D. from Carol Davila University of Medicine and Pharmacy (2017) 🎓. An Assistant Professor at the same university since 2019, she excels in teaching and research on pediatric pulmonology and gastroenterology. Her clinical expertise at “Grigore Alexandrescu” Emergency Hospital for Children includes contributions to groundbreaking clinical trials on inflammatory bowel diseases 🏥🔬. A dedicated volunteer with MD Caravana cu Medici 🤝, she brings healthcare to underserved communities. Dr. Matran’s active membership in ESPGHAN and advisory roles showcase her impactful influence in public health policy 🌍✨.

Publication Profile

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Educational Backgrounds

Assist. Prof. Dr. Roxana Matran embarked on her academic journey at the prestigious Central School in Bucharest, where she specialized in Mathematics-Informatics with bilingual French instruction (📘✏️). She continued her education at “Carol Davila” University of Medicine and Pharmacy, earning a Bachelor’s Degree in 2009 (🎓🩺). Driven by her passion for medicine, she pursued a Ph.D. at the same university, completing her thesis on factors contributing to pulmonary disease in cystic fibrosis between 2013 and 2017 (📄🫁). Her dedication and expertise in the medical field have solidified her reputation as a leading academic and researcher in Bucharest (🌟🏥).

Work Experiance

Assist. Prof. Dr. Roxana Matran is a distinguished pediatric gastroenterologist and academic based in Bucharest. She serves as a member of the Advisory Committee on Post-Vaccination Adverse Reactions, analyzing vaccine-related health concerns (💉📊). She is also a sub-investigator in pivotal clinical trials, including studies on Vedolizumab and Adalimumab for pediatric Crohn’s disease and ulcerative colitis (🔬📑). Dr. Matran volunteers with Caravana cu Medici, offering medical consultations in underserved Romanian villages (🚑🤝). As an Assistant Professor at “Carol Davila” University, she teaches fifth-year medical students and conducts extensive research (📚👩‍🔬). Her work at “Grigore Alexandrescu” Emergency Hospital focuses on consultations, rounds, and clinical studies (🏥👶).

Membership

Assist. Prof. Dr. Roxana Matran is an active member of esteemed professional organizations in her field. Since June 2019, she has been a Full Member of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), contributing to advancements in pediatric healthcare across Europe (🌍👶🩺). Additionally, she has been a dedicated member of the Romanian Society of Pediatrics since July 2016, working to promote excellence in pediatric medicine and research in her home country (🇷🇴📚💉). Her involvement in these societies underscores her commitment to improving children’s health and staying at the forefront of medical advancements (🌟🔬).

Conference and Seminars

Assist. Prof. Dr. Roxana Matran has an extensive track record of participation in prestigious medical events and specialized training programs worldwide. In 2024, she is set to attend the 5th Liver Transplant School in Brussels (25–28 September) and the ESPGHAN Mastercourse in Parenteral Nutrition in Linz, Austria (4–6 March). Her prior engagements include the ESPGHAN IBD Masterclass in Helsinki, Finland (2022) and the International Symposium on Pediatric Inflammatory Bowel Disease in Edinburgh, Scotland (2022). Over the years, she has honed her expertise in pediatric gastroenterology, nutrition, and pulmonology, attending courses in Italy 🇮🇹, Austria 🇦🇹, France 🇫🇷, and Greece 🇬🇷, and even completing a post-graduate program online 🌐.

Community Impact

Assist. Prof. Dr. Roxana Matran is deeply committed to serving underserved communities, demonstrating her passion for equitable healthcare access. She actively volunteers with MD Caravana cu Medici, a noble initiative providing essential medical consultations in impoverished Romanian villages 🏡. Through this work, Dr. Matran brings her expertise in pediatric gastroenterology and nutrition to those who need it most, offering care, guidance, and hope 🌟. Her dedication to improving public health goes beyond the clinic, reflecting a strong sense of compassion and responsibility toward marginalized populations 🤝. Dr. Matran’s efforts exemplify the true spirit of community service and medical care ❤️.

Clinical Expertise

Assist. Prof. Dr. Roxana Matran has made significant contributions to pediatric gastroenterology through her clinical practice, research, and involvement in clinical trials. As a pediatric gastroenterologist at “Grigore Alexandrescu” Emergency Hospital for Children 🏥, she seamlessly combines patient care with groundbreaking research. Dr. Matran has actively contributed as a subinvestigator for leading pharmaceutical companies, including Takeda Pharmaceuticals (VedolizumabSC-3003) and AbbVie (Adalimumab), advancing therapies for pediatric inflammatory bowel disease 🔬. She also researches post-vaccination adverse reactions as a member of the Advisory Committee at the Ministry of Health, ensuring better health outcomes for children globally 💉.

Research Focus

Dr. Roxana Elena Smădeanu’s research focus primarily revolves around pediatric health, with a special emphasis on diagnosing and managing complex diseases such as cystic fibrosis, intestinal tuberculosis, and respiratory conditions in children. Her work includes exploring microbiota’s role in functional abdominal pain disorders, respiratory symptomatology associated with COVID-19 in pediatric patients, and rare genetic syndromes like Menke-Hennekam syndrome. Additionally, her research delves into diagnostic methods like sweat conductivity in cystic fibrosis. This body of work aligns with clinical and laboratory research aimed at improving pediatric healthcare and diagnostics. 🧑‍🔬🩺👶

Publication Top Notes

Prof Dr. Ronit Sverdlov|Pharmacology|Best Researcher Award

Prof Dr. Ronit Sverdlov|Pharmacology|Best Researcher Award

Prof Dr. Ronit Sverdlov at Maastricht University,Netherlands

PROFILE  

ORCID

Scopus

 

Early Academic Pursuits 🎓

Dr. Ronit Shiri-Sverdlov’s academic journey began with a Master’s degree in Biochemistry and Cellular Biology from Tel-Aviv University in Israel, where she graduated magna cum laude. This period was instrumental in shaping her deep interest in cellular and molecular mechanisms, a theme that would remain central to her later work. Building on her foundational knowledge, she pursued a Ph.D. in Molecular Genetics at Tel-Aviv University’s Sheba Medical Center, under the supervision of Prof. E. Friedman. Her doctoral research, focused on identifying germline mutations in the BRCA1 and BRCA2 genes among high-risk Jewish and Arab populations, underscored her commitment to precision genetics and earned her a magna cum laude distinction upon graduation in 2002.

Professional Endeavors 💼

Dr. Shiri-Sverdlov joined Maastricht University’s Department of Molecular Genetics in 2001 as a postdoctoral researcher, working with Prof. M.H. Hofker. Her early postdoctoral work provided the groundwork for her lifelong focus on metabolic health, hepatic inflammation, and cholesterol metabolism. In 2004, she transitioned into a faculty position, first as an Assistant Professor and later, an Associate Professor by 2012. In 2016, she was appointed a Full Professor of Hepatic Inflammation and Metabolic Health, reflecting her leadership and expertise in the field. Dr. Shiri-Sverdlov currently leads a vibrant research team within the Faculty of Health, Medicine, and Life Sciences at Maastricht University, where she oversees projects focusing on liver disease, metabolic health, and inflammation under the NUTRIM School of Nutrition and Translational Research in Metabolism.

Contributions and Research Focus 🔬

Dr. Shiri-Sverdlov’s research centers on understanding and combating liver-related diseases, particularly non-alcoholic steatohepatitis (NASH), through molecular insights into cholesterol trafficking and hepatic inflammation. Her investigations have brought critical attention to lysosomal dysfunction as a biomarker for early NASH detection. This research has garnered substantial support, including a €1 million TKI grant in 2017 and several large fellowships from the Dutch Digestive Foundation and NWO ZonMw. Her work emphasizes the role of cholesterol metabolism in Kupffer cells (liver macrophages) and its impact on inflammatory pathways—a field where her studies continue to yield promising therapeutic insights.

Accolades and Recognition 🏆

Over the years, Dr. Shiri-Sverdlov has earned numerous prestigious awards. Her early career was marked by the VENI, VIDI, and ASPASIA fellowships from NWO ZonMw, which collectively supported her pioneering work in cholesterol metabolism and liver inflammation. She received the Marie Sklodowska-Curie Seal of Excellence in 2018, reflecting her proposal’s high evaluation score. She was also awarded the Education Prize by Maastricht University in 2018 for her leadership in developing the Biomedical Sciences curriculum. Additionally, she has been nominated for multiple awards, reflecting her influence in both research and teaching.

Impact and Influence 🌐

Dr. Shiri-Sverdlov has made a significant impact in the field of hepatic health through her research and mentorship. Her work on hepatic lysosomal biomarkers has been pivotal in early disease detection for NASH, with implications for both clinical practice and drug development. As a member of key grant committees, including the Netherlands Organization for Scientific Research (NWO) and the Novo Nordisk Foundation, she actively shapes the research landscape. Her collaboration with researchers across Europe, including those at the University of Reading and Strasbourg University, has contributed to a robust network of shared knowledge and advances in metabolic health.

Legacy and Future Contributions 🌱

Looking to the future, Dr. Shiri-Sverdlov is committed to advancing the understanding of liver diseases through cutting-edge research. Her work not only contributes to therapeutic advancements in NASH and hepatic inflammation but also inspires the next generation of scientists. Through her teaching roles, she continues to influence and guide students in Biomedical Sciences and Nutrition, instilling in them a commitment to rigorous research. Her legacy is further enriched by her leadership in scientific societies, where she champions innovative approaches to metabolic and hepatic health research.

🎓Publication 

Plasma cathepsin D as an early indicator of alcohol-related liver disease

  • Authors   :Li, M., Houben, T., Bitorina, A.V., Thiele, M., Shiri-Sverdlov, R.
    JHEP Reports,
  • Year         :2024

The Modulatory Effects of Fatty Acids on Cancer Progression

  • Authors   :Westheim, A.J.F., Stoffels, L.M., Dubois, L.J., Shiri-Sverdlov, R., Theys, J.
  • Journal    : Biomedicines
  • Year         :2023

All Roads Lead to Cathepsins: The Role of Cathepsins in Non-Alcoholic Steatohepatitis-Induced Hepatocellular Carcinoma

  • Authors   :van Mourik, H., Li, M., Baumgartner, S., Theys, J., Shiri-Sverdlov, R.
  • Journal    :Biomedicines
  • Year         :2022

Fatty Acids as a Tool to Boost Cancer Immunotherapy Efficacy

  • Authors   : Westheim, A.J.F., Stoffels, L.M., Dubois, L.J., Shiri-Sverdlov, R., Theys, J.
  • Journal    : Frontiers in Nutrition
  • Year         :2022

Serum CathepsinD in pregnancy: Relation with metabolic and inflammatory markers and effects of fish oils and probiotics

  • Authors   : Mokkala, K., Gustafsson, J., Vahlberg, T., Plat, J., Laitinen, K.
  • Journal    :Nutrition, Metabolism and Cardiovascular Diseases
  • Year         :2022