Ayaz Ahmed | Drug Discovery and Development | Best Researcher Award

Ayaz Ahmed | Drug Discovery and Development | Best Researcher Award

Dr Ayaz Ahmed, ICCBS – University of Karachi, Pakistan

Dr. Ayaz Ahmed 🧬🔬 is a Principal Investigator and Assistant Professor at the Dr. Panjwani Center for Molecular Medicine and Drug Research (PCMD), ICCBS, University of Karachi, Pakistan. With a Ph.D. in Biochemistry and Molecular Biology from Dalian Medical University, China, and an M.Sc. in Microbiology from the University of Karachi, his research focuses on microbial profiling, anti-biofilm agents, and infectious disease models. Dr. Ahmed has supervised numerous postgraduate students and received multiple international awards, including recognition from the American Society for Microbiology and Bill & Melinda Gates Foundation. He also leads funded projects on combating antibiotic-resistant pathogens. 🌟

Publication Profile

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Qualifications

Dr. Ayaz Ahmed holds a Ph.D. in Biochemistry and Molecular Biology from Dalian Medical University, China (2012), and a Master’s in Microbiology from the University of Karachi, Pakistan (2006, First Division). 🧬🎓 His doctoral research focused on the “Microbial profiling of dental plaque/Biofilm from dental caries and periodontitis patients” and explored the effects of Lactobacillus species on S. mutans biofilm formation. 🦷🔬 With a strong academic foundation and research expertise in microbiology and molecular biology, Dr. Ayaz contributes significantly to the understanding of microbial interactions in dental health and disease. 🌟

Job Responsibilities

Dr. Ayaz Ahmed is a Principal Investigator at the Cell Biology Lab, where he oversees the Imaging Facility, maintaining high-end fluorescence and light microscopes. He supports students by assisting them in acquiring high-quality images for their theses and manuscripts. Dr. Ahmed also manages the National Animal Facility for Laboratory Animal Research and Care. He supervises routine animal house operations and collaborates with a veterinary doctor to maintain SPF rats, mice, and hamsters. He is responsible for establishing models for infectious diseases and memory deficits to evaluate the efficacy of natural compounds. Dr. Ahmed also conducts toxicological studies and trains students in ethical animal research practices. 🧬🔬🐁

Student Supervised

Dr. Ayaz Ahmed and his team of dedicated researchers have made significant strides in their exploration of innovative therapeutic strategies. Among the Ph.D. candidates, Zulfiqar Ahmed’s research on controlling salmonellosis through probiotics in poultry, Binte Zehra’s study on modulating the metastatic potential of NSCLC, and Jazib Shafiq’s investigation into gut dysbiosis and anxiety have all been awarded. Additionally, Afshan Shams, Yamina Usmani, and Shariqa Khuwaja are examining the potential of natural and synthetic compounds in combating oral cancer and other diseases. Several M. Phil. students are also contributing to research on antimicrobial resistance and cancer therapies. 🧪🔬🧫

Honors and Awards

Dr. Ayaz Ahmed has earned numerous accolades throughout his distinguished career. In 2024, he received the Award for Collaborative Scientific Achievement from the Institute of Food Science and Technology, Chinese Academy of Agriculture Science, Beijing. He also became an International Federation for Biosafety Association (IFBA) Certified Biological Waste Management Professional and Bio-risk Management Professional in 2023. Dr. Ahmed was selected as a Mentor for the ASM Future Leaders Mentoring Fellowship Program in 2023 and was awarded the Health Security Partner Grant by the Bill & Melinda Gates Foundation in 2021. He has also earned prestigious travel awards and fellowships, including the American Society for Microbiology ID Fellowship and the Science and Technology Talent Award. 🏅🌍🦠

Completed Projects

Dr. Ayaz Ahmed has led multiple impactful research projects focused on combating multidrug-resistant microorganisms and improving public health. His research on the effect of synthetic and natural compounds on biofilm formation was funded by the Higher Education Commission of Pakistan (HEC) under project # HEC No: PD-IPFP/HRD/HEC/ 2013/1182. He also contributed to projects such as Personal Protective Equipment for Sindh Poultry Vaccine Center (funded by CRDF Global, USA), and oral pathogens related to dental caries (funded by ICCBS). Notably, his work on antimicrobial-resistant water contaminants, funded by the U.S.-Pakistan Centers for Advanced Studies in Water, aims to improve water quality. He further advanced research on antimicrobial and antibiofilm agents targeting Acinetobacter baumannii and Klebsiella pneumonia with funding from HEC. 💧🔬🦠

Professional Experience

Dr. Ayaz Ahmed has had a distinguished career in academia and research. Since June 2017, he has been serving as an Assistant Professor at the International Center for Chemical and Biological Sciences, University of Karachi. Prior to this, he worked as a Senior Research Officer at the same institution from November 2013 to June 2017. Dr. Ahmed also pursued Post-Doctoral training in Behavioral Sciences at Hunan Drug Safety Evaluation in Changsha, China, from January 2016 to February 2017. His earlier roles include Assistant Professor on Interim Placement, Research Officer in Avian Influenza Vaccine Production, and a research intern in the National Internship Program. 🧪📚

Professional Membership

Dr. Ayaz Ahmed is an active member of several prestigious professional organizations, contributing significantly to the fields of microbiology and infectious diseases. His memberships include the American Society for Microbiology (ASM) 🦠, the Pakistan Biological Safety Association (PBSA) 🧫, and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) 🌍. Additionally, he is a member of the American Association of Cancer Research (AACR) 🎗️ and the Medical Microbiology & Infectious Disease Society of Pakistan (MMIDSP) 🇵🇰. These memberships reflect his commitment to advancing research and innovation in microbiology, infectious diseases, and cancer research.

Research Focus

Dr. Ayaz Ayaz Ahmed research focus primarily revolves around microbiology, particularly in the fields of gut microbiota analysis, antimicrobial resistance, and biofilm formation. His studies often investigate the interactions between microorganisms and the human or animal host, such as comparing gut microbe profiles between healthy individuals and those with conditions like hyperthyroidism and liver cirrhosis. Additionally, Dr. Ahmed explores innovative therapeutic approaches, including the development of antimicrobial agents, such as nanoparticles conjugated with antibiotics to combat biofilm-forming pathogens like Klebsiella pneumoniae and Staphylococcus aureus. His work has significant implications for medical microbiology and the treatment of infectious diseases. 🦠🔬

Publication Top Notes

Gut microbe analysis between hyperthyroid and healthy individuals

Phylogenetic and biological characterization of Newcastle disease virus isolates from Pakistan

Biofilm inhibitory effect of chlorhexidine conjugated gold nanoparticles against Klebsiella pneumoniae

Comparison of the gut microbe profiles and numbers between patients with liver cirrhosis and healthy individuals

Rifampicin conjugated silver nanoparticles: a new arena for development of antibiofilm potential against methicillin resistant Staphylococcus aureus and Klebsiella pneumoniae

Effect of Lactobacillus species on Streptococcus mutans biofilm formation.

Comparison of oral microbiota in orthodontic patients and healthy individuals

Synthesis and Chemosensing of Nitrofurazone using Olive oil based Silver Nanoparticles (O-AgNPs)

Isolation of dihydrobenzofuran derivatives from ethnomedicinal species Polygonum barbatum as anticancer compounds

Prof. Rasha Azzam|Drug Discovery and Development|Best Researcher Award

Prof. Rasha Azzam|Drug Discovery and Development |Best Researcher Award

Prof. Rasha Azzam at Helwan University,Egypt

PROFILE  

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Early Academic Pursuits 🎓

Prof. Rasha A. Azzam’s academic journey began with her outstanding performance in chemistry at Helwan University, Egypt, where she graduated with a Bachelor of Science (B.Sc.) in Chemistry in 1993. Her excellence in academia was recognized early on, as she graduated with class honors and was placed on the Dean’s List. Driven by her passion for organic chemistry, she pursued a Master of Science (M.Sc.) degree in Organic Chemistry at Helwan University, completing it in 1996. Her academic curiosity and dedication led her to further her studies internationally, earning a prestigious Ph.D. in Organic Chemistry in 2003 from the Catholic University of Leuven in Belgium. Her diverse educational background laid the foundation for a career defined by groundbreaking research and academic excellence.

Professional Endeavors 🧑‍🔬

Prof. Azzam’s professional career spans over two decades of teaching, research, and leadership in various prestigious academic institutions across the globe. She is currently a Professor of Organic Chemistry at the Faculty of Science, Helwan University, where she has been contributing since 2021. Prior to this, she held the position of Associate Professor of Organic Chemistry at the same institution from 2016 to 2021, demonstrating her upward trajectory in academia.

Her teaching and research influence extended beyond Egypt. She has held positions as an Associate Professor at Taibah University in Saudi Arabia, Nigerian Turkish Nile University in Nigeria, and the American University in Nigeria, where she was a co-founder of the Petroleum Chemistry Program. Additionally, she has served as a Visiting Professor at Virginia Commonwealth University in 2024, further showcasing her international academic reach.

Contributions and Research Focus 🔬

Prof. Azzam’s research focuses on organic and medicinal chemistry, with a particular emphasis on green synthesis, nanomaterials, and antiviral agents. One of her key research interests is the development of new methods for synthesizing compounds with potential anticancer and antimicrobial properties. Her recent project, “Synthesis of new sulfa derivatives under ultrasonic irradiation as potential anticancer/antimicrobial agents,” funded by Helwan University in 2021, highlights her innovative approach to organic synthesis.

Prof. Azzam’s work also explores environmentally friendly technologies, as demonstrated by her research on “green technology based on nanoporous biodegradable polymeric membranes” for wastewater treatment, funded by the Academy of Scientific Research Technology (ASRT). She has also conducted pioneering work on nanomaterials and their applications in industrial processes, such as her research on thermoplastic elastomers based on petrochemicals and the development of anti-COVID-19 agents incorporated into nanofibrous mats.

Her research output is extensive, and she has presented several projects on global platforms, including her work on antiviral therapeutic agents and nanomaterials. Her research contributions are shaping the future of organic chemistry, particularly in the domains of green chemistry and medical applications.

Accolades and Recognition 🏆

Prof. Azzam’s excellence in research and community service has been recognized through numerous awards and honors. In 2023, she received the prestigious Prince Mohammed Bin Fahd Scientific Award for her contributions to scientific production that serves community development within the framework of sustainable development goals. In the same year, she was honored with Helwan University’s Outstanding Scientific Achievement Award in Basic and Applied Sciences.

She has also been recognized for her mentoring and supervision of students, receiving Best Master Thesis Awards for two of her master’s students, Rasha Essam (2020) and Heba Elboshi (2023). Her commitment to advancing research was further acknowledged when she received the Research Excellence Awards for her students, Rokia Ramadan (2019) and Rasha Essam (2020). Additionally, Prof. Azzam was awarded a Silver Medal from the Academy of Scientific Research Technology (ASRT) in 2018 for her outstanding contributions to science.

Her impact extends internationally, with her receiving the Outstanding Faculty Member Award from the American University in Nigeria in 2007, and a research scholarship from the Catholic University of Leuven in 2001.

Impact and Influence 🌍

Prof. Azzam’s influence is felt not only through her research but also through her active participation in the scientific community. She serves as a Review Editor for Organic Chemistry on the Editorial Board of Frontiers in Chemistry and as an editor for the Journal of Chemistry and The Scientific World Journal, both published by Hindawi. She is also a grant evaluator for the Fulbright Binational Scholarship Program, where she helps assess the next generation of academic leaders.

Her commitment to education and community service is reflected in her involvement in organizing training workshops for high school teachers and instructing lab sessions for the AUN Community School. Prof. Azzam is also a member of the Egyptian Society for Basic Sciences, where she contributes to the development of the scientific community in Egypt.

Legacy and Future Contributions 🌟

Prof. Rasha A. Azzam’s legacy is built on her unwavering dedication to advancing organic chemistry, fostering academic excellence, and mentoring the next generation of scientists. Her research has laid the groundwork for significant developments in green chemistry, nanomaterials, and medicinal chemistry. With her continued focus on innovative solutions for pressing global challenges, such as wastewater treatment and the development of antiviral agents, she is poised to make even more impactful contributions in the years to come.

🎓Publication 

In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives

  • Authors   :Toka I. Ismail; Nashwa El-Khazragy; Rasha A. Azzam
  • Journal    :RSC Advances
  • Year         :2024

Novel High-Performance Functionalized and Grafted Bio-Based Chitosan Adsorbents for the Efficient and Selective Removal of Toxic Heavy Metals from Contaminated Water

  • Authors   :Mohammad Monir; Rasha E. Elsayed; Rasha Azzam; Tarek M. Madkour
  • Journal    :Polymers
  • Year         :2024

Crystal structure of 4-(benzo[d]thiazol-2-yl)-1,2-dimethyl-1H-pyrazol-3(2H)-one

  • Authors   :Heba A. Elboshi; Rasha A. Azzam; Galal H. Elgemeie; Peter G. Jones
  • Journal    :Acta Crystallographica Section E Crystallographic Communications
  • Year         :2024

Synthesis of New Guanidine Benzothiazole Derivative and Its Application as Eco-Friendly Corrosion Inhibitor

  • Authors   : Abdel-karim, Amal M.; Azzam, Rasha A.; Shehata, Omnia S.; Adly, Mohamed A.; El-Shamy, Omnia A. A.; El-Mahdy, Gamal A.
  • Journal    :Chemistry
  • Year         :2023

Crystal structure of 2-{[5-(methylsulfanyl)-4-phenyl-4H-1,2,4-triazol-3-yl]methyl}benzo[d]thiazole

  • Authors   : Rasha A. Azzam; Galal H. Elgemeie; Heba A. Elboshi; Peter G. Jones
  • Journal    :Crystallographica Section E Crystallographic Communications
  • Year         :2023

Prof.Mohamed Abdel-Aziz, Drug Discovery and Development,Best Researcher Award-1133

Prof.Mohamed Abdel-Aziz, Drug Discovery and Development ,Best Researcher Award

Prof.Mohamed Abdel-Aziz, at National Research Centre,Egypt

Author Profile

🎓 Education:

He earned his PhD in Microbiology from Ain Shams University, specializing in Physiological and Genetical Studies on Dextranase Formation by Fungi. His academic journey includes a Master’s degree from Mansoura University and a Bachelor’s degree in Botany.

🔍 Research Focus:

Dr. Abdel-Aziz’s research primarily focuses on Microbial Chemistry, with extensive contributions to understanding microbial enzymes and bioactive compounds.

🌐 International Collaborations:

He has participated in several scientific missions and collaborations worldwide, including Italy, Great Britain, China, Germany, and Sweden, enriching his research with diverse perspectives.

📘 Publications:

Dr. Abdel-Aziz has authored over 145 publications, including original articles, reviews, and books, notably contributing to advancements in microbiology and biotechnology.

🏆 Achievements:

He holds seven patents and has been involved in numerous national and international research projects, enhancing the field’s knowledge and applications.

🌟 Recognition:

With an h-index of 31 and over 3000 citations, his work continues to influence the scientific community globally.

🎓Publication Top Noted:

Paper Title : Effect of plasma superficial treatments on antibacterial functionalization and coloration of cellulosic fabrics

  • Authors: Eid B. M. and Abdel-Aziz M. S. Ibrahim N. A.
  • Journal: Applied Surface Science
  • Year: 2017
Paper Title :Preparation of polystyrene nanocomposites based on silver nanoparticles using marine bacterium for packaging
    • Authors: Ahmed M Youssef, Mohamed S Abdel-Aziz
    • Journal:Polymer-Plastics Technology and Engineering
    • Year: 2013
Paper Title : Seven naphtho-γ-pyrones from the marine-derived fungus Alternaria alternata: structure elucidation and biological properties
  • Authors: Mohamed Shaaban, Khaled A Shaaban, Mohamed S Abdel-Aziz
  • Journal:Organic and medicinal chemistry letters
  • Year: 2012
Paper Title :Seven naphtho-γ-pyrones from the marine-derived fungus Alternaria alternata: structure elucidation and biological properties
  • Authors: Mohamed Shaaban, Khaled A Shaaban, Mohamed S Abdel-Aziz
  • Journal:Organic and medicinal chemistry letters
  • Year: 2012

Paper Title :Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide

  • Authors: El-Shimaa MN Abdel-Hafez, Gamal El-Din AA Abuo-Rahma, Mohamed Abdel-Aziz, Mohamed F Radwan, Hassan H Farag
  • Journal:Bioorganic & medicinal chemistry
  • Year: 2009