Assoc Prof Dr .Xing-Xing Fan, Immunotherapy ,Best Researcher Award

Assoc Prof Dr .Xing-Xing Fan at Macau University of Science and Technology,China

Author Profile

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🎓 Academic Qualifications:

1. Ph.D., Chinese Medicines, Macau University of Science and Technology, Macau, 2014
2. M.Sc., Pathogenesis, Tianjin Medical University, China, 2010
3. M.D., Clinical Medicine, Tianjin Medical University, China, 2007

🔬 Research Interests:

1. Development of small molecule targeted drugs.
2. CAR-T cell therapy for lung cancer.
3. Nanobodies generation for restoring T cell anti-tumor activity.

📅 Professional Chronology:

1. Associate Professor, Macau University of Science and Technology, July 2023 – Present
2. Assistant Professor, Macau University of Science and Technology, September 2017 – June 2023
3. Postdoctoral Fellow, Macau University of Science and Technology, September 2014 – September 2017

📚 Academic Institutions and Social Work:

1. Standing Director:
   1. Executive Director of the Professional Committee of Immunology of Traditional Chinese Medicine of the World Federation of Chinese Medicine Societies
   2. Executive Director of the Council of Macao International Cooperation Alliance for Rheumatology Research
2. Membership:
   1. American Association for Cancer Research
   2. The Consortium for Globalization of Chinese Medicine
3. Editor or Board Member of SCI Journals:
   1. Associate Editor of Heliyon
   2. Guest Editor of Pharmacological Research, Oxidative Medicine and Cellular Longevity, and Frontiers in Pharmacology

📖 Representative Publications within 5 Years:

1. Li R#, Fan X#, Jiang Z, Huang J, Gavine P, Fehlings M, Nardin A, Liu L, Cao Y, Leung E. Longitudinal high-dimensional analysis identifies biomarkers of response to anti-PD-1 immunotherapy. Nature Communications. Just accepted. IF=17.694.
2. Yi-Han Zuo, Wei-Na Gao, Ya-Jia Xie, Sheng-Yong Yang, Jin-Tai Zhou, Hai-Hai Liang & Xing-Xing Fan*. Tumor PKCδ instigates immune exclusion in EGFR-mutated non– small cell lung cancer. BMC Medicine. volume 20, Article number: 470 (2022). IF=11.806.
3. Elaine Lai-Han Leung#, Xing-Xing Fan#, Ju-Min Huang, Chen Huang, Hong Lin, Ya- Bing Cao. Holistic immunomodulation for small cell lung cancer. Seminars in Cancer Biology. 2022 Dec 2; S1044-579X (22)00245-0. IF= 17.012.
4. Ying Xie, Sen-Ling Feng, Fang He, Pei-Yu Yan, Xiao-Jun Yao, Xing-Xing Fan*, Elaine Lai-Han Leung, Hua Zhou. Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer. Pharmacological Research. 2022 Dec;186:106514. IF= 10.330.
5. YJ Xie, M Huang, D Li, JC Hou, HH Liang, AA Nasim, JM Huang, C Xie, Xing-xing Fan*. Bacteria-based nanodrug for anticancer therapy. Pharmacological Research, 106282. IF= 10.330.
6. Min Huang, Fang He, Dan Li, Ya-Jia Xie, Elaine Lai-Han Leung, Xing-Xing Fan*. PA- MSHA Induces Inflamed Tumor Microenvironment and Sensitizes Tumor to Anti-PD-1 Therapy, Cell Death & Disease. 2022 Nov 7;13(11):931. IF= 9.685.

🎓Publication Top Noted: