Michael Harrison | Precision Medicine | Best Researcher Award

Michael Harrison | Precision Medicine | Best Researcher Award

Dr. Michael Harrison, UCSF, United States

Dr. Michael Harrison is a pioneering pediatric surgeon and fetal therapy expert. 🎓 He earned his B.A. from Yale (1965) and M.D. from Harvard Medical School (1969), followed by extensive surgical training at Massachusetts General Hospital and fellowships in pediatric surgery. 🏥 He joined UCSF in 1978, where he became a Full Professor and founded the Fetal Treatment Center. 👶 His groundbreaking work in fetal surgery has earned him numerous accolades, including the Golden Plate Award and presidency of the International Fetal Medicine and Surgery Society. 🌍 Now Professor Emeritus at UCSF, he continues to shape the field of pediatric surgery. ✨

Publication Profile

Scopus

Education

Dr. Michael Harrison 🎓 began his academic journey at Yale University (1961-1965), earning a B.A. before pursuing his M.D. in Medicine at Harvard Medical School (1965-1969) 🏥. He completed his surgical residency at Massachusetts General Hospital (1969-1971) and advanced his expertise as a Postdoctoral Fellow in Allergy & Immunology at the National Institute of Allergy and Infectious Disease (1971-1973) 🧬. Returning to Massachusetts General, he served as a Senior Resident (1973-1974) and Chief Resident (1974-1975) 🔬. Further specializing, he completed fellowships in Pediatric Surgery at Rikshospitalet (1975-1976) 🇳🇴 and Children’s Hospital of Los Angeles (1976-1978) 👶🩺.

Experience

Dr. Michael Harrison 🏥 has been a Founding Member of the International Fetal Medicine and Surgery Society (1981-present) 👶 and has served as its President at the Annual Meeting (1989, 2006) 🎤. He has contributed as a Committee Member for the Medical Advisory Committee of the American Association of Tissue Banks (1993-present) 🧬 and chaired the Committee on Fetal Therapy at APSA (1994-1996) 🏥. A Board Member of the International Society of the Fetus as Patient (1997-present) 🌍, he also consults for the MOMS study (2003-present) 🤰. Since 2010, he has been Vice President of the California Academy of Medicine 📚.

Awards

Dr. Michael Harrison 🏅 has received numerous prestigious honors, including the Golden Plate Award (1982, 1988) 🏆, the William E. Ladd Medal (2010) 🏅, and the Lifetime Achievement Award (2011) 🌟 from the International Fetal Medicine and Surgery Society. He was elected to the Institute of Medicine (2009) 📜 and honored with the Denis Browne Gold Medal (2013) 🏵️. As a celebrated lecturer, he has delivered keynote addresses worldwide 🌍, including at the Nobel Minisymposium on Fetal Medicine (1998) 🎤. His groundbreaking contributions in pediatric surgery have earned him global recognition and lasting influence in the field.

Research Focus

Dr. Michael R. Harrison is a pioneering surgeon and researcher in pediatric surgery and fetal therapy 🏥👶. His work focuses on maternal-fetal surgery, particularly for conditions like esophageal atresia and diaphragmatic hernia. He has contributed to the development of magnetic compression anastomosis 🧲 and other innovative minimally invasive surgical devices 🔬. His research advances the treatment of complex congenital disorders and improves outcomes for newborns. With numerous publications, he has significantly impacted pediatric device clinical trials 📊. Dr. Harrison’s groundbreaking contributions continue to shape the future of pediatric and fetal surgical care 🚼✨.

Publication Top Notes

Pediatric Device Clinical Trials Activity: 1999–2022

Lessons Learned From the First-In-Human Compassionate Use of Connect-EA™ in Ten Patients With Esophageal Atresia

Evaluation of a Magnetic Compression Anastomosis for Jejunoileal Partial Diversion in Rhesus Macaques

Sonographic Predictors of Survival in Fetal Diaphragmatic Hernia

Beyond the gut: spectrum of magnetic surgery devices

The Rearing of Maternal–Fetal Surgery: The Maturation of a Field from Conception to Adulthood

The novel application of an emerging device for salvage of primary repair in high-risk complex esophageal atresia

Esophageal Magnetic Compression Anastomosis in Esophageal Atresia Repair: A PRISMA-Compliant Systematic Review and Comparison with a Novel Approach

An experimental study on long term outcomes after magnetic esophageal compression anastomosis in piglets

Novel device for endoluminal esophageal atresia repair: First-in-human experience

Assoc Prof Dr. Muhammad Raza| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Razal Kotaska| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Raza at University of Gujrat,Pakistan

PROFILE  

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Early Academic Pursuits 🎓

Dr. Muhammad Asam Raza embarked on his academic journey with a strong foundation in the natural sciences. After completing his F.Sc. from the Board of Intermediate and Secondary Education, Gujranwala in 1998, he pursued a B.Sc. in Zoology, Botany, and Chemistry from the University of Punjab, Lahore. His profound interest in chemistry led him to continue his academic endeavors with an M.Sc. in Chemistry from the same institution, where his research centered on “Production of xylanases and cellulases in bioreactor by using Chaetomium thermophile.”

Dr. Raza’s pursuit of higher education took him to GC University, Lahore, where he earned both his M.Phil. and Ph.D. degrees in Chemistry. His M.Phil. research focused on the “Phytochemical and antioxidant screening of Mimusops elengi,” while his Ph.D. dissertation was centered on the “Extraction, structure elucidation, and microbial transformation of protease inhibitors from medicinal plants.” These early research topics highlight his passion for bioactive compounds and natural product chemistry, setting the stage for a career rich in scientific exploration.

Professional Endeavors 👨‍🏫

Dr. Raza’s academic and research career took off when he joined the University of Gujrat in 2011 as an Assistant Professor in the Department of Chemistry. Over the years, he contributed extensively to teaching and research at the institution, shaping the academic futures of numerous students. His dedication and excellence in the field of chemistry led to his promotion to Associate Professor in December 2020.

In addition to his role as a professor, Dr. Raza has held various administrative responsibilities at the University of Gujrat, including serving as the coordinator of the Four Year Degree Program in Chemistry, time table in-charge, and head examiner for the B.Sc./B.S. Program. His involvement in organizing industrial and study tours has further enriched the academic experiences of students, giving them a practical understanding of their field of study.

Contributions and Research Focus 🔬

Dr. Raza’s research portfolio is vast, focusing primarily on bioactive compounds, their purification, synthesis, and characterization. His expertise in chromatographic techniques, such as Thin Layer Chromatography (TLC), Column Chromatography, and High-Performance Liquid Chromatography (HPLC), has led to significant breakthroughs in the purification of bioactive compounds. He is also proficient in Gas Chromatography-Mass Spectrometry (GC-MS), enabling him to identify volatile compounds and elucidate the structures of synthesized and natural products.

His research interests also encompass microbial transformation, enzyme inhibition, antioxidant studies, and kinetic studies of various reactions. He has explored both natural and synthetic compounds for their antimicrobial and enzyme inhibition properties, significantly contributing to the field of medicinal chemistry. Additionally, Dr. Raza’s work on the production and characterization of xylanases and cellulases from fungal cultures demonstrates his expertise in enzyme technology, which holds potential for industrial applications.

Docking studies, using different software, have also been a significant focus in Dr. Raza’s research. This computational approach to studying molecular interactions has opened new avenues in drug design and development, further enhancing his contributions to the chemistry of biologically active molecules.

Accolades and Recognition 🏆

Throughout his career, Dr. Muhammad Asam Raza has received numerous accolades, reflecting his excellence in both academic and research fields. He was awarded a Merit Scholarship in 1997 from the District Council of Hafizabad, which was an early indicator of his potential. Later, he received the Indigenous PhD 5000 Fellowship Program from the Higher Education Commission (HEC) of Pakistan, a prestigious scholarship that supported his doctoral studies. Dr. Raza’s contributions to research were also acknowledged by the Pakistan Council for Science and Technology (PCST) with Research Productivity Awards in 2012 and 2013.

Further recognition of his expertise came when Dr. Raza was approved as a Ph.D. supervisor by the HEC, allowing him to mentor and guide future researchers in their academic pursuits. Additionally, he secured a research project worth half a million rupees from the HEC, demonstrating his ability to attract significant funding for his research endeavors.

Impact and Influence 🌍

Dr. Raza’s impact extends beyond the classroom and laboratory. His active participation in organizing national and international workshops, seminars, and symposiums has significantly contributed to the dissemination of knowledge in the scientific community. He has been instrumental in hosting events such as the “Two Days Interdisciplinary National Workshop on Chromatography & Mass Spectrometry” and the “Two Days International Symposium on Developments in Contemporary Chemistry” at the University of Gujrat.

His administrative roles have also been influential, particularly his contributions as a member of various departmental committees, including the Departmental Doctoral/MPhil Program Committee (DDMPC) and the Purchase Committee (NRPU). Dr. Raza’s participation in such committees highlights his commitment to improving the academic and research infrastructure at the University of Gujrat.

Furthermore, Dr. Raza’s work as a reviewer for scientific journals and project evaluator for research proposals under the NRPU has contributed to maintaining the standards of scientific inquiry in Pakistan. His expertise is frequently sought in assessing research proposals and reviewing academic papers, ensuring the advancement of chemistry research in the country.

Legacy and Future Contributions 🌱

Dr. Muhammad Asam Raza’s contributions to the field of chemistry, both in terms of research and teaching, have left a lasting legacy at the University of Gujrat and beyond. His commitment to advancing knowledge in bioactive compounds, enzyme inhibition, and molecular docking studies is not only reflected in his research but also in the numerous students he has mentored over the years.

Looking forward, Dr. Raza is poised to continue making significant contributions to the field of chemistry, particularly in the areas of natural product chemistry, enzyme technology, and computational drug design. His future work will likely focus on the synthesis and characterization of biologically active compounds, with potential applications in pharmaceuticals, agriculture, and biotechnology.

Dr. Raza’s legacy will undoubtedly be defined by his passion for chemistry, his dedication to teaching, and his tireless pursuit of scientific excellence, which will continue to inspire future generations of researchers.

🎓Publication 

Acetylcholine and butyrylcholine esterase inhibitory potential of newly synthesized halogenated compounds: In vitro, in silico and MD simulation

  • Authors   : emanur Yesilbağ; Muhammad Asam Raza; Zeshan Ali Sandhu; Umme Farwa; Emine Berrin Poyraz;
  • Journal    :Molecular Structure
  • Year         :2025

Advances in the Optimization of Fe Nanoparticles: Unlocking Antifungal Properties for Biomedical Applications

  • Authors   : Sandhu, Z.A.; Raza, M.A.; Alqurashi, A.; Sajid, S.; Ashraf, S.; Imtiaz, K.; Aman, F.; Alessa, A.H.; Shamsi, M.B.; Latif, M.
  • Journal    :Pharmaceutics
  • Year         :2024

Association of APO B gene polymorphisms with the development of myocardial infarction in Pakistani population

  • Authors   : Arshad, M.; Iqbal, R.; Raza, M.; Bashir, R.; Ahmed, T.; Parveen, A.
  • Journal    :Gene
  • Year         :2024

Beyond graphene: exploring the potential of MXene anodes for enhanced lithium–sulfur battery performance

  • Authors   : Zeshan Ali Sandhu; Kainat Imtiaz; Muhammad Asam Raza; Adnan Ashraf; Areej Tubassum; Sajawal Khan; Umme Farwa; Ali Haider Bhalli; Abdullah G. Al-Sehemi
  • Journal    :RSC Advances
  • Year         :2024

Biomedical properties, characterization of seaweeds species and antimicrobial activity,Propriedades biomédicas, caracterização de espécies de algas marinhas e atividade antimicrobiana

  • Authors   : Rizwan, S.; Saleem, M.; Hassan, H.U.; Raza, M.A.; Kanwal, R.; Kabir, M.; Ghaffar, R.A.; Fadladdin, Y.A.J.; Rafiq, N.; Matin, A. et al.
  • Journal    :Brazilian Journal of Biology
  • Year         :2024

Assoc Prof Dr. Karel Kotaska| Precision Medicine |Best Researcher Award

Assoc Prof Dr. Karel Kotaska|Precision Medicine|Best Researcher Award

Assoc Prof Dr. Karel Kotaska at University Hospital Motol,Czech Republic

PROFILE  

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🎓 Early Academic Pursuits

Kotaška’s academic journey began at the Sladkovského High School in Prague, where he completed his secondary education in 1992. Following this, he embarked on an educational path that laid the foundation for his career in biochemistry. In 1997, he graduated from the Institute of Chemical Technology in Prague, earning a Dipl. Ing. in Chemistry Engineering, specializing in Biomedical Engineering. His thirst for knowledge led him to pursue postgraduate studies at the 2nd Medical Faculty of Charles University, Prague, where he specialized in Biochemistry and Pathobiochemistry, culminating in a Ph.D. in 2003. His doctoral research and thesis defense were pivotal moments in shaping his future career as a leading figure in biochemistry.

🏢 Professional Endeavors

Kotaška’s professional career has spanned over two decades, beginning in 2002 at the Department of Medical Chemistry and Clinical Biochemistry at the University Hospital Motol, one of the largest medical facilities in the Czech Republic. As a research scientist and specialist, he quickly became an integral part of the team, contributing significantly to research projects and clinical laboratory functions. In 2015, Kotaška was appointed Associate Professor in Medical Chemistry and Clinical Biochemistry at the 2nd Medical Faculty of Charles University, further solidifying his standing as an expert in his field. His role expanded into quality management, becoming an auditor and overseeing laboratory processes to ensure adherence to ISO standards and good laboratory practices.

🔬 Contributions and Research Focus

Kotaška’s research interests are broad and impactful, covering various aspects of biochemistry and clinical diagnostics. His primary research focuses on the role of natriuretic peptides in cardiovascular diseases, a field critical for advancing the understanding and treatment of heart-related conditions. He has also made significant strides in investigating biomarkers associated with cardiovascular, neurological, inflammatory, and tumor diseases.

In addition to his contributions to molecular genetics, where he has explored genetic variants linked to diseases, Kotaška is well-versed in laboratory management and external quality control. He has been involved in the harmonization and standardization of laboratory practices, ensuring that diagnostics adhere to global standards. His work in urinalysis and infrared spectroscopy has also pushed forward diagnostic capabilities in clinical biochemistry.

🏆 Accolades and Recognition

Kotaška’s impressive career has not gone unnoticed. He has received numerous grant awards for his research, including projects funded by the Grant Agency of the Ministry of Health (MH) and Charles University. His studies have ranged from investigating biomarkers for organ failure to exploring the molecular biology of neurofibromatosis and cathepsin B activity in bladder carcinoma.

Notably, his project on the biological behavior of urological malignancies, which involved long-term monitoring of tissue, serum, and urine samples, stands out as a pioneering effort in the field of cancer research. Additionally, his ongoing work since 2021 on the effect of combined treatments in chronic heart failure in animal models has further contributed to advancing therapeutic approaches.

🌍 Impact and Influence

Beyond his laboratory work, Kotaška has made substantial contributions to academia and clinical education. Since 2008, he has been involved in teaching postgraduate students and has served as a lecturer at several institutions, including the Czech Technical University, where he taught biomedical engineering and laboratory techniques until 2023. As a member of the education team in postgraduate doctoral studies, he has mentored countless students, helping shape the next generation of biochemists and medical professionals.

Kotaška’s influence extends to his role as a reviewer for several prestigious biomedical journals, such as the Central European Journal of Biology, Open Heart Journal, and Diagnostics. His expertise in statistical methods, including regression analysis, survival analysis, and data evaluation, has positioned him as a thought leader in clinical diagnostics.

📚 Publications and Peer Review

With 66 peer-reviewed publications and 12 book chapters to his name, Kotaška’s work has been widely recognized and cited in the scientific community. His publications span critical topics in clinical biochemistry, genetic research, and molecular diagnostics. His H-index of 10 reflects the significant impact of his research, with 317 citations from scholars and professionals in related fields. His commitment to advancing clinical diagnostics and biochemistry is evident in his body of work, which continues to inform and guide research in these areas.

🏅 Legacy and Future Contributions

Kotaška’s legacy is rooted in his contributions to clinical biochemistry and medical diagnostics. His work on improving diagnostic efficiency, standardizing laboratory procedures, and exploring biomarkers in diseases has set a benchmark in the medical field. As a corresponding member of prominent international organizations, such as the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and the International Federation of Clinical Chemistry (IFCC), his influence extends beyond the Czech Republic to the global scientific community.

Karel Kotaška’s future contributions are likely to focus on further enhancing diagnostic tools and treatment methods, particularly in the fields of cardiovascular diseases and cancer research. His ongoing work in investigating the effects of innovative therapeutic treatments for chronic heart failure demonstrates his commitment to improving patient outcomes. Additionally, his leadership in laboratory standardization efforts will continue to shape the practices of clinical laboratories worldwide, ensuring that diagnostics remain accurate, efficient, and globally harmonized.

🌟 Conclusion

Karel Kotaška’s career is a testament to his dedication to advancing medical science and education. His multifaceted contributions as a researcher, educator, and laboratory manager have left a lasting impact on the fields of biochemistry and clinical diagnostics. His work continues to influence both the scientific community and clinical practices, ensuring his legacy as a leading figure in medical chemistry and clinical biochemistry for years to come.

🎓Publication 

Polycyanoacrylate (super glue) as bladder concretion in a patient after bilateral inguinal hernioplasty

  • Authors   : Karel Kotaška; Milan Polák; Antonín Brisuda; Richard Průša
  • Journal    : Annals of Clinical Biochemistry
  • Year         :2020