Valory Anne Vailoces | Ophthalmic Pharmacology | Best Researcher Award

Valory Anne Vailoces | Ophthalmic Pharmacology | Best Researcher Award

Ms. Valory Anne Vailoces, George Washington University School of Medicine & Health Sciences, United States

Ms. Valory Anne Vailoces is a dedicated biomedical scientist and medical student at George Washington University School of Medicine and Health Sciences. She earned her B.S. in Biomedical Sciences from the University of Central Florida in 2021 🎓. Valory conducts impactful ophthalmology research 👁️ under Dr. Michael Tolentino and collaborated with the Miami Itch Center on dermatological studies 🧬. Her pioneering work on rifampicin eye drops for age-related macular degeneration led to a preclinical IND application 💊. She also serves as a senior officer at Hearts for the Homeless International ❤️, combining science with social service.

Publication Profile

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Education

Valory Anne S. Vailoces earned her B.S. in Biomedical Sciences in 2021 from the University of Central Florida 🧬. She is currently pursuing her medical degree at the George Washington University School of Medicine and Health Sciences 🏥. Alongside her studies, she is actively involved in ophthalmology research 👁️ under the mentorship of Dr. Michael Tolentino. Valory also serves as a senior officer for Hearts for the Homeless International ❤️, a non-profit organization that delivers preventative healthcare services 🩺 to underserved and homeless populations, demonstrating her deep commitment to both science and social impact 🌍.

Professional Memberships

Ms. Valory Anne Vailoces does not currently hold memberships in professional organizations 🤝, her dedication to academic excellence and impactful research in ophthalmology, dermatology, and health management 🧠👁️📊 stands out on its own. Her active involvement in translational research, along with her service to the community through Hearts for the Homeless International ❤️, reflects a strong commitment to both science and humanity 🌍. As she continues to advance in her medical education and research career 🧬, professional affiliations are expected to follow as a natural progression of her growing influence in the field 🚀.

Research Focus

Ms. Valory Anne Vailoces focuses her research on ophthalmology, dermatology, and therapeutic innovation 🧪👁️🧴. Her groundbreaking work includes developing rifampicin eye drops for treating exudative age-related macular degeneration (AMD) 🧬, a major cause of vision loss worldwide 🌍. Additionally, she explores immune-modulating therapeutic nanoparticles for safer clinical applications and leads investigations into aquagenic pruritus, a rare skin condition causing severe itching 💧🧖‍♀️. Through a blend of biomedical science, nanomedicine, and patient-centered studies, Valory contributes to advancing precision treatment modalities with the potential to transform clinical practice 🚀🩺. Her work spans innovative drug delivery and patient quality-of-life research.

Publication Top Notes

Development of Rifampicin Eye Drops for the Treatment of Exudative Age-Related Macular Degeneration

Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials

Aquagenic pruritus: A web‐based survey study exploring itch characteristics, therapeutic options and patient perspectives

Prof Dr. Birgit Lorenz|Ophthalmologie| Best Paper Award

Prof Dr. Birgit Lorenz |Ophthalmologie|Best Paper Award|

Prof Dr. Birgit Lorenz at TransMIT Center of Translational Ophthalmology c/o Justus-Liebig, Germany

PROFILE  

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Early Academic Pursuits 🎓

Prof. Dr. med. Birgit Lorenz began her distinguished academic journey at the Ludwig-Maximilians-University in Munich, Germany. Her medical studies spanned from 1968 to 1974, with an enriching stint at the Sorbonne/Hôpital Cochin in Paris, France. Demonstrating academic excellence early on, she earned her MD thesis with the highest honors, summa cum laude, in Biochemistry from Ludwig-Maximilians-University in 1974. This solid foundation set the stage for a prolific career in ophthalmology and medical genetics.

Following her graduation, Prof. Lorenz pursued a residency in ophthalmology at the Department of Ophthalmology at Ludwig-Maximilians-University Munich, completing it between 1977 and 1982. During this time, she not only honed her clinical skills but also deepened her commitment to research, eventually leading to a PhD thesis (Habilitation) from the same institution in 1989. Her early academic endeavors also included a prestigious research fellowship at the Institute of Ophthalmology in London, where she worked with renowned institutions like Moorfields Eye Hospital and the Hospital for Sick Children.

Professional Endeavors 🏥

Prof. Lorenz’s professional career is marked by a series of significant appointments at prestigious institutions. Her journey began as a Fellow and Consultant in Ophthalmology at Ludwig-Maximilians-University Munich (1982-1991), where she built a reputation as a dedicated clinician and researcher. In 1991, she transitioned to the University of Regensburg, where she served as a Full Professor of Pediatric Ophthalmology, Strabismology, and Ophthalmic Genetics. Her tenure at Regensburg lasted until 2007, during which time she also led the Department of Pediatric Ophthalmology.

In 2007, Prof. Lorenz moved to Justus-Liebig University Giessen, taking on the role of Full Professor and Chairman of the Department of Ophthalmology. For over a decade, she spearheaded advancements in ophthalmic genetics and pediatric ophthalmology. Even after her official retirement, she continued her impactful work as a Professor Emeritus and Senior Clinical Expert for Inherited Retinal Degenerations at the University of Bonn (2020-2022). Currently, she directs the TransMIT Centre for Translational Ophthalmology at TransMIT GmbH, affiliated with Justus-Liebig-University Giessen.

Contributions and Research Focus 🔬

Throughout her illustrious career, Prof. Lorenz has made profound contributions to the fields of ophthalmic genetics, pediatric ophthalmology, and retinal degenerations. Her research has often focused on inherited retinal diseases (IRDs), with an emphasis on understanding their molecular underpinnings and developing potential gene therapies. A prime example of her work includes her involvement in a significant DFG-funded project on chromatic pupillometry, aimed at creating new biomarkers to quantify retinal function and assess the efficacy of gene therapies.

Prof. Lorenz has also been instrumental in several other groundbreaking projects, such as developing device-independent algorithms for enhanced optical coherence tomography (OCT) in retinal diseases and quantifying rod-and-cone function in X-linked retinal dystrophies. Her research has consistently been at the forefront of efforts to translate scientific discoveries into clinical applications, particularly in the realm of gene and cell-based therapies for neuroretinal degeneration.

Accolades and Recognition 🏆

Prof. Lorenz’s contributions to ophthalmology have been recognized with numerous awards and honors. She is a Fellow of the European Board of Ophthalmology (FEBO) and has received prestigious awards such as the Lifetime Achievement Award from the European Paediatric Ophthalmology Society (EPOS) and the Science Award from the Bielschowsky Society. Additionally, she has been elected as a member of esteemed organizations such as the Academia Ophthalmologica Internationalis (AOI) and the European Academy of Ophthalmology (EAO).

Her leadership in the field is also evident from her roles in various international organizations. She served as the President of the International Society of Genetic Eye Diseases and Retinoblastoma (ISGEDR) from 2016 to 2020 and has been an influential figure in the European Vision Institute Clinical Research Network (EVICR.net) and the German Ophthalmological Society (DOG).

Impact and Influence 🌍

Prof. Lorenz’s impact on the field of ophthalmology extends beyond her research and clinical work. She has been a key organizer of international meetings, bringing together experts to discuss the latest advancements in genetic eye diseases, pediatric ophthalmology, and retinal degenerations. Notable events she has organized include the Annual Meeting of the Société de Génétique Ophtalmologique Francophone and the Meeting of the International Society of Genetic Eye Diseases and Retinoblastoma.

Her influence is further reflected in her role as a reviewer for numerous peer-reviewed journals and as a member of editorial boards. She has also been a mentor to countless students and young researchers, shaping the future of ophthalmic genetics through her dedication to teaching and mentorship.

Legacy and Future Contributions 🧬

As Prof. Lorenz continues to contribute to the field through her work at the TransMIT Centre for Translational Ophthalmology, her legacy is one of pioneering research, clinical excellence, and unwavering commitment to advancing the understanding and treatment of genetic eye diseases. Her work has paved the way for future breakthroughs in gene therapy, and her influence will undoubtedly continue to inspire and guide new generations of ophthalmologists and researchers.

In the years to come, Prof. Lorenz’s contributions will likely expand as she remains actively involved in cutting-edge research and international collaborations. Her ongoing projects and the knowledge she imparts to her students and colleagues ensure that her impact on the field will endure for many years, shaping the future of ophthalmology and genetics.

🎓Publication 

Twelve-month Natural History Study of Centrosomal Protein 290 (CEP290)-associated Inherited Retinal Degeneration

  • Authors   :Pierce, E.A., Ashimatey, B.S., Jayasundera, T., Myers, R., Pennesi, M.E..
  • Journal    :Ophthalmology Science.
  • Year         :2024

Treated Cases of Retinopathy of Prematurity in Germany: 10-Year Data from the Retina.net Retinopathy of Prematurity Registry

  • Authors   :Pfeil, J.M., Barth, T., Lagrèze, W.A., Völker, M., Hagemann, U.
  • Journal    :Ophthalmology Retina
  • Year         :2024

Comparability of input parameters in the German Retina.net ROP registry and the EU-ROP registry – An exemplary comparison

  • Authors   :Winter, K., Pfeil, J.M., Engmann, H., Bartmann, I.R., Stahl, A.
  • Journal    :Acta Ophthalmologica,
  • Year         :2024

Single Center Experience with Voretigene Neparvovec Gene Augmentation Therapy in RPE65 Mutation–Associated Inherited Retinal Degeneration in a Clinical Setting

Characterising the refractive error in paediatric patients with congenital stationary night blindness: a multicentre study