Mrs. Ana Catarina Sousa| Personalized Medicine|Best Researcher Award

Mrs. Ana Catarina Sousa| Personalized Medicine|Best Researcher Award

Mrs. Ana Catarina Sousa at School of Medicine and Biomedical Sciences – University of Porto (ICBAS),Portugal

PROFILE  

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Early Academic Pursuits 🎓

Ana Catarina Soares de Sousa’s academic journey is marked by a strong focus on the intersection of healthcare and engineering. She completed her Master’s degree in Health Services Management and Economics in 2021 at the prestigious University of Porto, one of the top academic institutions in Portugal. This degree provided her with in-depth knowledge of the economic and managerial aspects of healthcare services, a vital skill set for navigating the complexities of healthcare systems and improving service delivery.

Prior to this, she earned a Master’s degree in Integrated Master in Bioengineering in 2018 at the same university. This program combined principles of biology, medicine, and engineering, equipping her with a solid foundation in biomedical engineering—particularly crucial for her subsequent research on biomaterials and medical technologies. Her dual educational background uniquely positions her to address both the technical and systemic challenges in health services, a hallmark of her later work.

Since 2020, Ana Catarina has been pursuing a PhD in Biomedical Sciences at the Abel Salazar Institute of Biomedical Sciences (ICBAS) within the University of Porto. Her PhD program focuses on interdisciplinary research in medical and health sciences, allowing her to build on her expertise in biomaterials and tissue engineering, while contributing to innovations in medical biotechnology.

Professional Endeavors 💼

Ana Catarina’s professional journey reflects a commitment to both research and practical applications in the biomedical sciences. Throughout her career, she has participated in numerous research projects, taking on key roles both as a research fellow and a lead researcher. Since 2018, she has contributed to seven major research projects, focusing on cutting-edge biomedical technologies and solutions for healthcare challenges.

Among her significant projects are:

  • InnovaBIOMAS (2023–2026): An innovative biofabrication system for creating multi-tissue scaffolds for joint disease treatments. This project highlights her expertise in biomaterials and tissue engineering.
  • H2Cure (2021–2024): A project developing novel formulations, including honey-based gels and dressings with gelan gum and hyaluronic acid for wound care—an intersection of regenerative medicine and biotechnology.
  • PRECOGFIL (2020–2024): This initiative explores the development of pre-tensioned cog threads for transvaginal repair of compartment prolapse, showing her application of bioengineering in women’s health.
  • Bone2Move (2018–2021): Focused on 4D scaffolds for bone defect repair, it underscores her involvement in the evolution of tissue engineering techniques.

Her work has crossed the boundaries of disciplines, spanning medical technology, veterinary applications, regenerative medicine, and materials engineering.

Contributions and Research Focus 🔬

Ana Catarina’s contributions to the biomedical field have been prolific. With 30 peer-reviewed journal articles and 2 book chapters, she has established herself as a thought leader in the scientific community. Her research encompasses a range of fields, but she is particularly recognized for her work in Medical Biotechnology, with a specific emphasis on biomaterials and tissue engineering.

Some of the key areas of her research include:

  • Regenerative Medicine: Her focus on developing advanced biomaterials that can aid in tissue regeneration and healing has practical applications in orthopedics, wound care, and surgical interventions.
  • Veterinary Medicine: Her interdisciplinary approach extends into veterinary science, where she applies biomedical engineering techniques to animal health.
  • Translational Medicine: Ana Catarina is committed to bridging the gap between laboratory research and clinical applications, ensuring that her discoveries can have a real-world impact on patient care.
  • Sustainable Chemistry: She has also been involved in developing environmentally friendly materials and chemical processes for healthcare applications, contributing to sustainability in medical technology.
  • Chemistry for Health: Her work in this area includes the development of biomaterials and formulations aimed at improving health outcomes through innovative chemistry.

With 214 co-authors in her published works, she has demonstrated an impressive ability to collaborate across disciplines and with researchers from around the world.

Accolades and Recognition 🏆

Ana Catarina’s work has not gone unnoticed. She has been the recipient of one award that recognizes her contributions to the field of biomedical sciences. This accolade highlights her innovative approach to healthcare challenges and her ability to bring together diverse disciplines in pursuit of improved health outcomes.

In addition to her award, she has also been instrumental in the scientific community as an event organizer. She has successfully organized three major events, bringing together researchers, healthcare professionals, and industry experts to discuss the latest advancements in biomedical sciences and medical technologies.

Impact and Influence 🌍

Ana Catarina’s work in biomedical sciences has the potential to make a far-reaching impact on both human and animal health. By focusing on innovative biomaterials and medical biotechnology, she is contributing to the development of new treatments that could transform the way diseases are managed and treated. Her research on scaffold-based tissue regeneration and wound care formulations has implications for patients suffering from joint diseases, chronic wounds, and surgical complications.

Her work in the development of advanced biofabrication systems and pre-tensioned threads for surgical repairs also promises to improve surgical outcomes and post-surgical recovery for patients. Moreover, her focus on sustainable chemical processes ensures that her contributions are not only medically valuable but also environmentally responsible.

Legacy and Future Contributions 🌟

Looking ahead, Ana Catarina is poised to continue making groundbreaking contributions to the field of biomedical sciences. Her ongoing projects, particularly those related to biomaterials for regenerative medicine, have the potential to lead to new therapies that will benefit both human and veterinary medicine.

Her focus on translational research ensures that her work will continue to have a direct impact on clinical practices, making her a key figure in the future of medical biotechnology. As she progresses in her PhD journey and beyond, Ana Catarina Soares de Sousa is likely to leave a lasting legacy in the fields of tissue engineering and healthcare innovation.

In the years to come, her work is expected to influence not only scientific research but also the development of new medical technologies that will improve patient care and healthcare systems around the world.

🎓Publication 

Peripheral nerve injury treatments and advances: one health perspective

  • Authors   :Bruna Lopes, Patrícia Sousa, Rui Alvites, Mariana Branquinho, Ana Catarina Sousa, Carla Mendonça, Luís Miguel Atayde, Ana Lúcia Luís, Artur SP Varejão, Ana Colette Maurício
  • Journal    :International journal of molecular sciences
  • Year         :2022

Dental pulp stem cells and Bonelike® for bone regeneration in ovine model

  • Authors   : JM Campos, AC Sousa, AR Caseiro, SS Pedrosa, PO Pinto, MV Branqu
  • Journal    :Regenerative biomaterials
  • Year         :2019

Mesenchymal stem/stromal cells and their paracrine activity—immunomodulation mechanisms and how to influence the therapeutic potential

  • Authors   : Rui Alvites, Mariana Branquinho, Ana C Sousa, Bruna Lopes, Patrícia Sousa, Ana Colette Maurício
  • Journal    :Pharmaceutics
  • Year         :2022

Assessment of the environmental impacts of medical devices: a review

  • Authors   :Ana Catarina Sousa, Anabela Veiga, Ana Collete Maurício, Maria Ascensão Lopes, José Domingos Santos, Belmira Neto
  • Journal    :Environment, Development and Sustainability
  • Year         :2021

Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo

  • Authors   :Rui D Alvites, Mariana V Branquinho, Ana C Sousa, Irina Amorim, Rui Magalhães, Filipa João, Diogo Almeida, Sandra Amado, Justina Prada, Isabel Pires, Federica Zen, Stefania Raimondo, Ana L Luís, Stefano Geuna, Artur SP Varejão, Ana C Maurício
  • Journal    :Stem cells international
  • Year         :2021

 

Dr. ANTHOULA LAZARIS| Precision Medicine|Best Researcher Award

Dr. ANTHOULA LAZARIS, Precision Medicine,Best Researcher Award

Dr. ANTHOULA LAZARIS, at MCGILL UNIV. HEALTH CTR,Canada

PROFILE

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📚 Early Academic Pursuits :

Anthoula Lazaris began her academic journey with a B.Sc. in Microbiology and Immunology from McGill University (1983-1986), where she developed a solid foundation in the biological sciences. She continued at McGill, earning a Ph.D. in Biochemistry from the Faculty of Medicine (1988-1992). Her postdoctoral studies took her to Leiden, The Netherlands, where she further honed her expertise in Medical Biochemistry (1992-1994). This robust educational background laid the groundwork for her illustrious career in academia and biotechnology.

🏢Professional Endeavors :

Lazaris has accumulated over 30 years of combined experience in academia and industry, holding management and senior-level positions. Currently, she is a scientist at the Research Institute of the McGill University Health Centre (RI-MUHC), focusing on metastatic and metabolic diseases with an emphasis on translational research. Her career highlights include:

  • Liver Disease Biobank: In 2011, Lazaris established a Liver Disease Biobank in collaboration with Dr. P Metrakos, collecting biospecimens from patients with liver-related diseases.
  • Quebec Extracellular Vesicle Consortium: She spearheaded this consortium with Drs. Rak and Olivier, demonstrating her leadership in collaborative research initiatives.
  • CIHR Training Grant: Lazaris co-wrote and secured a substantial CIHR training grant for the Goodman Cancer Centre, illustrating her proficiency in obtaining competitive funding.

🔬Contributions and Research Focus :

Lazaris’s research contributions span several critical areas:

  • Metastatic Disease: She focuses on colorectal cancer liver metastases (CRCLM), investigating molecular mechanisms to predict therapeutic responses and developing new biomarkers.
  • Translational Research: Her work bridges basic and clinical research, aiming to translate findings into precision therapies for cancer patients. Notably, her research on predictors of therapeutic responses to antiangiogenic agents has been groundbreaking.
  • Liver Diseases: Lazaris’s research also covers hepatocellular carcinoma, cholangiocarcinomas, and NAFLD/NASH, contributing to the broader understanding of these conditions.

🏆Accolades and Recognition :

Throughout her career, Lazaris has received numerous accolades:

  • Scientific American Award: In 2002, she was recognized in the category of Research Leader in Chemical and Materials for her work on transgenic animals producing spider silk.
  • Genome Canada White Paper: She spearheaded the writing of a white paper on “Disease Mechanisms,” which was integrated into Genome Quebec’s strategic plan.
  • Scientific Publications: Her research has been published in prestigious journals like Nature and Science, highlighting her contributions to molecular biology and oncology.

🌍Impact and Influence :

Lazaris’s work has had a profound impact on both the scientific community and public health:

  • Innovations in Biotechnology: She was part of the team that demonstrated the first expression of soluble spider silk, which can be spun into fibers with remarkable mechanical properties.
  • Transgenic Research Network: As the Executive Director of the Quebec Transgenic Research Network, Lazaris unified the capabilities of researchers across Quebec, securing significant funding and fostering collaborative research.
  • Cloned Animals: She was part of the team that generated the world’s first cloned goat and Canada’s first large transgenic animal, showcasing her pioneering contributions to genetic engineering.

🌟Legacy and Future Contributions :

Anthoula Lazaris’s legacy is marked by her pioneering research, leadership in collaborative scientific endeavors, and significant contributions to translational medicine. Her work continues to influence the fields of molecular biology, biotechnology, and cancer research. Looking forward, Lazaris is expected to further her contributions to personalized medicine, leveraging her extensive experience and innovative approach to address pressing challenges in healthcare. Her dedication to translational research and collaborative spirit ensures that her impact will be felt for years to come.

🎓Publication 

Predictive biomarker discovery in cancer using a unique AI model based on set theory

Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 – β-catenin cascade to promote liver tumorigenesis

    • Authors :Sinha, S., Aizawa, S., Nakano, Y., Guccione, E., Tsukamoto, H.
    • Journal   :Nature Communications
    • Year       : 2023

Targeting Liver Metastases to Potentiate Immunotherapy in MS-Stable Colorectal Cancer—A Review of the Literature

  • Authors  :, Zlotnik, O., Krzywon, L., Bloom, J., Lazaris, A., Metrakos, P.
  • Journal    :Cancers
  • Year         :  2023

Isolation of extracellular vesicles from human plasma samples: The importance of controls

  • Authors  :Tsamchoe, M., Petrillo, S., Lazaris, A., Metrakos, P.
  • Journal   : Biotechnology Journal
  • Year        :   2023

A Retrospective Study on the Role of Metformin in Colorectal Cancer Liver Metastases

  • Authors  :Rada, M., Krzywon, L., Petrillo, S., Lazaris, A., Metrakos, P.
  • Journal   : Biotechnology 
  • Year        :  2023

Assoc Prof Dr.Mahmoud Nikseresht, Precision Medicine,Best Researcher Award-1172

Assoc Prof Dr.Mahmoud Nikseresht ,Precision Medicine ,Best Researcher Award

Assoc Prof Dr.Mahmoud Nikseresht, at Ilam Branch, Islamic Azad University, Iran

Author Profile

 

Education:

  • Postdoctoral Clinical Research Fellow (2016): Institute of Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Project: “Detraining-induced alterations in adipokines and cardio-metabolic risk factors after nonlinear periodized resistance and aerobic interval training in obese men.”
  • Ph.D. in Exercise Physiology (2013): Central Tehran Branch, Islamic Azad University, Tehran, Iran.
    Dissertation: “Effects of nonlinear resistance and high-intensity interval aerobic training on resting levels of cytokines in obese men.”
  • Master of Science in Sport and Exercise Physiology (2006): Central Tehran Branch, Islamic Azad University, Tehran, Iran.
    Thesis: “The effects of endurance, plyometrics, and concurrent training on salivary immunoglobulins and bio-energetic characteristics in soccer players.”
  • Bachelor of Science in Physical Education and Sport Sciences (2004): Kharazmi University, Tehran, Iran.

Employment:

  • Associate Professor (2021-present): Department of Exercise Physiology, Islamic Azad University, Ilam Branch.
  • Assistant Professor (2013-2021): Department of Exercise Physiology, Islamic Azad University, Ilam Branch.
  • Instructor (2007-2013): Department of Physical Education and Sport Sciences, Islamic Azad University, Ilam Branch.

Professional Memberships:

  • Member of the European College of Sports Sciences (ECSS) (2010-present)
  • Chair of the ECSS (2018-present)

Publications and Research: Dr. Nikseresht has contributed significantly to the field of exercise physiology through his research and publications. Some of his notable works include:

  • In Progress:

    1. Assessing Physical Activity Levels Among Secondary Students in the West of Iran: A Cohort Study (2023)
    2. Heart Rate and Aerobic Endurance Performance Response during an Incremental Exercise to Exhaustion in Hookah-Smoking Soccer Players (2022)

🎓Publication Top Noted:

Paper Title :Effects of nonlinear resistance and aerobic interval training on cytokines and insulin resistance in sedentary men who are obese

  • Authors   : Mahmoud Nikseresht, Hamid Agha-Alinejad, Mohammad A Azarbayjani, Khosrow Ebrahim
  • Journal    :The Journal of Strength & Conditioning Research
  • Year         : 2014
Paper Title : Detraining-induced alterations in adipokines and cardiometabolic risk factors after nonlinear periodized resistance and aerobic interval training in obese men
    • Authors :   Mahmoud Nikseresht, Mohammad Reza Hafezi Ahmadi, Mehdi Hedayati
    • Journal   : Applied Physiology, Nutrition, and Metabolism
    • Year       : 2016
Paper Title :  Inflammatory markers and adipocytokine responses to exercise training and detraining in men who are obese
  • Authors  :  Mahmoud Nikseresht, Nourkhoda Sadeghifard, Hamid Agha-Alinejad, Khosrow Ebrahim
  • Journal    : The Journal of Strength & Conditioning Research
  • Year         :  2014
Paper Title : Comparison of serum cytokine levels in men who are obese or men who are lean: effects of nonlinear periodized resistance training and obesity
  • Authors  :  Mahmoud Nikseresht
  • Journal   : The Journal of Strength & Conditioning Research
  • Year        :   2018

Paper Title :Comparison of serum interleukin-18 and C-reactive protein levels in obese and non-obese young men: Effects of exercise training and obesity

  • Authors  :  Mahmood Nikseresht
  • Journal   : Journal of Sabzevar University of Medical Sciences
  • Year        : 2018