Jinyu Liu | Drug Discovery and Development | Best Researcher Award

Jinyu Liu | Drug Discovery and Development | Best Researcher Award

School of Public Health Jilin University | China

Mr. Jinyu Liu is a distinguished scholar in the fields of stem cell biology, regenerative medicine, toxicology, tissue engineering, and tumor pathobiology. He began his academic journey at the N. Bethune University of Medical Sciences, where he successfully completed his MD, followed by a Master’s degree in Toxicology and a Ph.D. in Biochemistry at the Institute of Regenerative Medicine. Building on this strong academic foundation, he embarked on an extensive research and teaching career across several leading institutions globally.Mr. Liu’s professional path includes serving as an Environmental Protection Engineer at the Songliao Water Conservancy Agency before moving into academic research and teaching. He held research positions at Zurich University Hospital in Switzerland, where he contributed significantly to studies in dermatology and regenerative medicine, followed by a research faculty position at the State University of New York at Buffalo in the Department of Biological and Chemical Engineering. Returning to China, he joined Jilin University, holding roles such as Vice Chair of the Department of Pathobiology, Chair of the Department of Toxicology, and later Professor at the School of Public Health, where he continues to teach and mentor future scientists.Throughout his career, Mr. Liu has contributed extensively to scientific literature with publications spanning diverse research areas. His works include studies on PBX1 attenuating MeHg-induced SH-SY5Y cell apoptosis, AT-PBX1 fusion protein alleviating LPS-induced acute lung injury, and viral hijacking of host DDX60 promoting Crimean-Congo hemorrhagic fever virus replication. He has explored type 3 diabetes and metabolic reprogramming of brain neurons, neurotoxic β-amyloid oligomers causing mitochondrial dysfunction in neurons, and research on the development and regeneration of hair follicles. His studies have also examined circadian clock regulation in hair follicle cycles, the role of PBX1 in mammalian kidneys, oxidative stress modulation in mesenchymal stem cells, and CRISPR-Cas12a-based detection of monkeypox virus.

Profile: Orcid

Featured Publications

Chen, Z., Liu, X., Zuo, K., Xin, Y., & Liu, J. (2025). TAT-PBX1 fusion protein alleviates LPS-induced acute lung injury via AMPK-TFAM signaling activation. Molecular Therapy.

Sui, Y., Marzi, A., Xu, Q., Liu, M., Liu, X., Liu, X., Wang, Y., Meng, X., Liu, Z., Li, Q., et al. (2025). Viral hijacking of host DDX60 promotes Crimean-Congo haemorrhagic fever virus replication via G-quadruplex unwinding. PLOS Pathogens, 21(6), e1013278.

Sui, Y., Liu, F., Zheng, S., Liu, X., Sun, P., Yao, C., Zhang, Y., Gao, H., Gao, X., & Liu, J. (2023). G-quadruplexes folding mediates downregulation of PBX1 expression in melanoma. Signal Transduction and Targeted Therapy, 8(1), 12.

Sui, Y., Xu, Q., Liu, M., Zuo, K., Liu, X., & Liu, J. (2022). CRISPR-Cas12a-based detection of monkeypox virus. Journal of Infection, 85(6), 702–769.

Ma, Y., Li, M., Liu, J., Pang, C., Zhang, J., Li, Y., & Fu, X. (2018). Location, isolation, and identification of mesenchymal stem cells from adult human sweat glands. Stem Cells International, Article ID 2090276.

Gaetan Ligat | Drug Discovery and Development | Best Researcher Award

Assoc. Prof. Dr. Gaetan Ligat | Drug Discovery and Development | Best Researcher Award

Assoc. Prof. Dr. Gaetan Ligat at Toulouse University | France

Assoc. Prof. Dr. Gaetan Ligat is a molecular virologist and principal investigator at Toulouse University, affiliated with INSERM UMR1291 and CNRS UMR5051. He leads the ViNeDys team at the Toulouse Institute for Infectious and Inflammatory Diseases, focusing on host–human cytomegalovirus interactions in brain tumors and therapeutic innovation. With extensive research and teaching experience across France, he has contributed to advancing antiviral strategies, mentoring young scientists, and promoting scientific communication. He is actively engaged in international collaborations, scientific societies, and community outreach, while securing multiple research grants to strengthen translational virology and oncology research.

Publication Profile 

Google Scholar

Education 

Assoc. Prof. Dr. Gaetan Ligat pursued his scientific training at Limoges University, France. He earned a Master of Science degree in Genetics and Physiology, which laid the foundation for his research career. He then advanced to doctoral studies at INSERM UMR1092, Limoges University, where he specialized in Molecular Virology, completing his PhD with distinction. His academic formation emphasized molecular biology, virus-host interactions, and translational virology, providing expertise in genetics, physiology, and applied biomedical sciences. This strong educational background enabled him to develop a career bridging fundamental research and therapeutic applications, particularly in virology, cancer biology, and innovative antiviral treatment strategies.

Experience 

Assoc. Prof. Dr. Gaetan Ligat is Associate Professor of Virology at Toulouse University, where he also serves as Principal Investigator and group leader of the ViNeDys team at the Infinity Institute. His work focuses on host–HCMV interactions and therapeutic innovation in brain tumors. Previously, he was a postdoctoral researcher at INSERM UMR1110 in Strasbourg, specializing in antiviral strategies. He began his research as a Master’s and PhD candidate at INSERM UMR1092, Limoges. Alongside research, he has coordinated training programs, practical courses, and supervised over 20 students. He is deeply involved in scientific societies, equality initiatives, and international collaborations.

Awards and Honors 

Assoc. Prof. Dr. Gaetan Ligat has received numerous prestigious recognitions, including the National Thesis Prize from the French Society of Microbiology and fellowships from the French National Agency for Research on AIDS and Viral Hepatitis (ANRS). He was awarded an ESCMID Research Grant, travel grants from the French Society of Microbiology, and registration bursaries for international congresses. His successful fundraising as principal investigator includes support from cancer foundations, patient associations, and Inserm/Regional PhD funding. These honors reflect both his scientific excellence and commitment to translational virology and oncology research. His awards highlight his impact on advancing antiviral and therapeutic research.

Research Focus 

Assoc. Prof. Dr. Gaetan Ligat research focuses on the molecular biology of human cytomegalovirus (HCMV) and its interaction with host cells, particularly in brain tumor environments. His work aims to understand how viral mechanisms contribute to disease progression and to identify novel therapeutic targets. He develops innovative antiviral strategies, including peptides and antibodies targeting HCMV protein interactions. His research also explores inflammatory responses, host-pathogen dynamics, and translational approaches for cancer treatment. Through collaborative projects and funded research programs, he seeks to bridge fundamental virology with therapeutic innovation, advancing the fight against viral infections and HCMV-related diseases in oncology.

Publication Top Notes

The human cytomegalovirus terminase complex as an antiviral target: a close-up view

Capsid assembly modulators as antiviral agents against HBV: molecular mechanisms and clinical perspectives

Hepatitis C virus (HCV)–apolipoprotein interactions and immune evasion and their impact on HCV vaccine design

Hepatitis B virus–host interactions and novel targets for viral cure

Hepatitis B virus core variants, liver fibrosis, and hepatocellular carcinoma

Targeting viral cccDNA for cure of chronic hepatitis B

The Yin and the Yang of extracellular vesicles during viral infections

Structures and divergent mechanisms in capsid maturation and stabilization following genome packaging of human cytomegalovirus and herpesviruses

Contrasting effect of new HCMV pUL54 mutations on antiviral drug susceptibility: benefits and limits of 3D analysis

Interferon‐Induced Transmembrane Proteins Mediate Viral Evasion in Acute and Chronic Hepatitis C Virus Infection

Identification of a short sequence in the HCMV terminase pUL56 essential for interaction with pUL89 subunit

Identification of amino acids essential for viral replication in the HCMV helicase-primase complex