lingcong KONG | Drug Discovery and Development | Best Researcher Award

lingcong KONG | Drug Discovery and Development | Best Researcher Award

Prof. lingcong KONG at Jilin Agriculture University, China.

Prof. Lingcong Kong is a dedicated veterinary scientist with a Ph.D. in Preventive Veterinary Medicine from Jilin Agricultural University πŸŽ“. He teaches courses like Veterinary Pharmacology and Animal Toxicology πŸ„ and actively mentors students in national competitions πŸ†. His research focuses on antimicrobial resistance, drug resistance mechanisms, and the development of resistance inhibitors in animal pathogens 🧫🦠. He has led numerous national and provincial projects, holds multiple patents for veterinary vaccines πŸ’‰, and has published extensively in high-impact journals πŸ“š. His work significantly enhances diagnostic tools and contributes to sustainable animal healthcare.

Publication ProfileΒ 

Scopus

Education

Prof. Lingcong Kong began his academic journey at the Inner Mongolia University for Nationalities, where he earned his Bachelor of Veterinary Medicine from September 2006 to July 2010 🐾. He then pursued advanced studies at Jilin Agricultural University, completing a Master’s degree in Basic Veterinary Medicine between 2010 and 2013 πŸ§ͺ. Driven by a deep passion for animal health, he continued at the same institution to earn his Ph.D. in Preventive Veterinary Medicine from September 2013 to July 2016 πŸ”¬. His education laid a strong foundation for his impactful contributions to veterinary science and research.

Experience

Prof. Lingcong Kong is a dedicated educator who teaches undergraduate courses such as “Veterinary Pharmacology”, “Veterinary Pharmacology Experiment”, and “Animal Toxicology” 🐾. At the graduate level, he lectures on “Veterinary Drug Research and Creation”, “Advanced Pharmacology”, and “Veterinary Pharmacology and Toxicology” πŸ’Š. He actively mentors students in scientific competitions, leading them to prestigious honors like the 2022 Internet+ National Award (2nd Prize) πŸ…, Provincial Award (1st Prize) πŸ₯‡, and innovation contests. His guidance also earned him the Outstanding Paper Award πŸ“ and the Dazenong Innovation Guidance Award in 2018 πŸŽ–οΈ, highlighting his commitment to academic excellence and innovation.

Awards

Prof. Lingcong Kong has pioneered breakthroughs in detecting and combating drug-resistant animal pathogens πŸ„πŸ§«. His innovations include PCR-ELISA rapid detection, immunomagnetic bead enrichment, and high-throughput methods for resistance gene testing πŸ§ͺ. He established a pathogenic bacteria resource library πŸ“š and developed functional probiotics to prevent animal diarrhea πŸ’Š. By identifying 8 key resistance inhibitor targets and 6 promising lead compounds, his work has revolutionized lab diagnostics, minimized economic losses in livestock, and enhanced ecological health πŸŒ±πŸ’Ό. His efforts significantly advance animal healthcare and veterinary pharmacology across Jilin Province and beyond.

Research FocusΒ 

Prof. Lingcong Kong focuses on veterinary pharmacology, particularly targeting antimicrobial resistance and infectious diseases in animals πŸ„πŸ¦ . His cutting-edge research includes discovering novel natural inhibitors like coniferaldehyde and protocatechuic aldehyde to combat Staphylococcus aureus πŸ§ͺπŸ”¬. He also explores gene transfer mechanisms, antibiotic degradation pathways, and repurposing small molecules to inhibit bacterial enzymes like KPC-2 πŸ’Š. By studying agents such as C15-bacillomycin D and antibacterial proteins from Bacillus velezensis, he contributes significantly to combatting multidrug-resistant pathogens in animal and environmental health.

Publication Top Notes

  • Discovery of coniferaldehyde as an inhibitor of caseinolytic protease to combat Staphylococcus aureus infections
  • Anti-infective therapy of inhibiting Staphylococcus aureus ClpP by protocatechuic aldehyde
  • Acidifiers promoted antibiotic resistance gene transfer via plasmid conjugation
  • Efficient degradation of tylosin by Kurthia gibsonii TYL-A1: performance, pathway, and genomics study
  • Repurposing tavaborole to combat resistant bacterial infections through competitive inhibition of KPC-2 and metabolic disruption
  • A Novel Protein Demonstrating Antibacterial Activity Against Multidrug-Resistant Escherichia coli Purified from Bacillus velezensis CB6
  • C15-bacillomycin D produced by Bacillus amyloliquefaciens 4-9-2 suppress Fusarium graminearum infection and mycotoxin biosynthesis

Xia Xiao | Pharmacodynamics | Best Researcher Award

Xia Xiao | Pharmacodynamics | Best Researcher Award

Assoc. Prof. Dr. Xia Xiao, Yangzhou University, China

Assoc. Prof. Dr. Xia Xiao is a distinguished researcher in veterinary microbiology at Yangzhou University. He earned his Ph.D. in Veterinary Science from South China Agricultural University (2015) πŸŽ“, specializing in bacteriophage-mediated antibiotic resistance. His research focuses on antimicrobial pharmacokinetics, novel antimicrobial agents, and bacterial resistance mechanisms πŸ¦ πŸ’Š. A former visiting scholar at UCLA (2018-2019), Dr. Xiao has published extensively in high-impact journals πŸ“š. His work contributes to the rational use of antibiotics and combating multidrug resistance, advancing veterinary and human medicine alike. πŸ†πŸ”

Publication Profile

Scopus

Education

Assoc. Prof. Dr. Xia Xiao is a leading veterinary microbiologist at Yangzhou University. He earned his Ph.D. in Veterinary Science from South China Agricultural University (2015) πŸŽ“, specializing in bacteriophage-mediated antibiotic resistance. As a former visiting scholar at UCLA (2018-2019) 🌍, his research focuses on antimicrobial pharmacokinetics, novel antimicrobial agents, and bacterial resistance mechanisms πŸ¦ πŸ’Š. Since 2020, he has been an Associate Professor, contributing to advancements in antibiotic utilization and resistance control. His work plays a crucial role in improving both veterinary and human medicine. πŸ“š

Experience

Assoc. Prof. Dr. Xia Xiao is a veterinary microbiologist at Yangzhou University, specializing in antimicrobial resistance πŸ¦ πŸ’Š. He earned his Ph.D. from South China Agricultural University (2015) πŸŽ“, focusing on bacteriophage-mediated antibiotic resistance. As a Visiting Scholar at UCLA (2018-2019) 🌍, he expanded his research through international collaborations, enhancing his contributions to the global scientific community πŸ”¬πŸ€. His work explores antibiotic pharmacokinetics, novel antimicrobial agents, and bacterial resistance strategies. Since 2020, he has been an Associate Professor, making impactful strides in veterinary and human medicine. πŸ“šπŸ†

Focus Areas

Assoc. Prof. Dr. Xia Xiao is a veterinary microbiologist at Yangzhou University, specializing in antimicrobial resistance and antibiotic optimization πŸ’ŠπŸ“Š. He earned his Ph.D. from South China Agricultural University (2015) πŸŽ“ and later expanded his research through international collaboration as a Visiting Scholar at UCLA (2018-2019) 🌍. His work focuses on pharmacokinetics-based antibiotic use, novel antimicrobial development, and strategies to combat bacterial resistance πŸ₯βš•οΈ. His groundbreaking research on bacteriophage-mediated resistance transmission addresses global health challenges, making significant contributions to veterinary and medical microbiology. πŸ“šπŸ†

Research Focus

Assoc. Prof. Dr. Xia Xiao’s research primarily focuses on antimicrobial resistance (AMR) πŸ¦ πŸ’Š, pharmacokinetics/pharmacodynamics (PK/PD) modeling πŸ“ŠπŸ§ͺ, and bacterial resistance mechanisms πŸ”¬πŸ§«. Her work explores the role of resistance genes, such as mcr-1, blaNDM-5, and tet(X4), in multidrug-resistant pathogens, including Klebsiella pneumoniae and Escherichia coli. She investigates novel strategies to combat AMR, including using natural compounds 🌿, repurposed drugs πŸ’‘, and PK/PD-based optimization πŸ“‰πŸ“ˆ. Her research has significant implications for developing effective treatments against drug-resistant infections in both humans and animals πŸ₯🐾.

Publication Top Notes

DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr-carrying Bacteria Through a Negative Feedback Regulatory Mechanism

Acetylshikonin Derived From Arnebia euchroma (Royle) Johnst Kills Multidrug-Resistant Gram-Positive Pathogens In Vitro and In Vivo

Acetylshikonin reduces the spread of antibiotic resistance via plasmid conjugation

The Food Additive Benzaldehyde Confers a Broad Antibiotic Tolerance by Modulating Bacterial Metabolism and Inhibiting the Formation of Bacterial Flagella

Gramine sensitizes Klebsiella pneumoniae to tigecycline killing

Characterization of a cfr-bearing integrative and conjugative element in Proteus cibarius coharbouring tet(X6) on the chromosome