Dr. Annie Zhang|Immunotherapy|Best Researcher Award

Dr. Annie Zhang|Immunotherapy|Best Researcher Award

Dr. Annie Zhang at Cambridge,United States

PROFILE  

 

Scopus

Dr. Annie Zhang embarked on her academic journey with a strong foundation in medicine and public health, earning an MD and an MPH. Her dual degrees equipped her with a nuanced understanding of clinical medicine and the critical public health frameworks essential for managing and preventing diseases at both population and individual levels. Driven by a commitment to advancing therapeutic options and improving patient outcomes, she honed her knowledge in both biostatistics and epidemiology. These skills have been foundational throughout her career, particularly in her roles focused on evidence generation and clinical research.

🌟 Professional Endeavors

Throughout her distinguished career, Dr. Zhang has held senior roles at prominent pharmaceutical companies, demonstrating her expertise in medical affairs, clinical research, and strategic evidence generation.

  1. Sanofi, Cambridge, MA
    As the Global Senior Medical Director in Immunology & Dermatology since 2018, Dr. Zhang has led impactful initiatives in Medical Evidence Generation within Global Medical Affairs. Her key achievements include winning Sanofi’s “Best of Best” award in 2023 and receiving a 1st Place Poster award at the American Academy of Dermatology (AAD) conference in 2024 for her work’s scientific importance. Her leadership has propelled Sanofi’s immunology initiatives, particularly through studies such as PEDISTAD and INFANTSTAD, which focus on disease modification and prevention of the atopic march.
  2. Apellis, Waltham, MA
    In her tenure as Medical Director at Apellis from January 2017 to December 2017, Dr. Zhang was responsible for strategic planning and clinical development in hematology, overseeing Phase II and III studies in conditions such as paroxysmal nocturnal hemoglobinuria (PNH) and autoimmune hemolytic anemia (AIHA). Her role included extensive interaction with thought leaders and the clinical team to design and optimize trial strategies.
  3. Biogen, Cambridge, MA
    From 2009 to 2016, Dr. Zhang held several pivotal roles at Biogen, advancing from Medical Director in Global Medical Affairs to leading biostatistical teams for key drug programs like Tecfidera. She worked on Tysabri’s lifecycle management, supporting clinical trial design, data generation, and publication strategies, especially in multiple sclerosis (MS). Her expertise in biostatistics and clinical research design strengthened Biogen’s data-driven approaches, particularly in Phase III and IV clinical trials.
  4. PAREXEL International, Lowell, MA
    Dr. Zhang worked as a Senior Biostatistician at PAREXEL from 2007 to 2009, leading biostatistical tasks across diverse therapeutic areas, including oncology, CNS disorders, and cardiovascular disease. Her meticulous approach ensured the quality and accuracy of statistical reports for clinical trials, contributing to numerous successful projects within the biostatistics team.
  5. New England Research Institutes, Watertown, MA
    Early in her career, Dr. Zhang served as an Associate Research Scientist at NERI from 2000 to 2007, where she conducted critical statistical analyses for clinical research, laying the groundwork for her later expertise in biostatistics and clinical study design.

💡 Contributions and Research Focus

Dr. Zhang’s research has centered around dermatology, immunology, and hematology. At Sanofi, her work in immunology has led to groundbreaking insights on skin barrier integrity and neuroimmune function, providing essential evidence for the prevention of atopic march. She has also driven significant advancements in real-world evidence generation, particularly in cross-functional collaboration with global market access and regulatory teams, demonstrating her strategic alignment with organizational goals and patient needs.

🏆 Accolades and Recognition

Dr. Zhang’s achievements have earned her numerous accolades, including the prestigious “Best of Best” award at Sanofi in 2023. In addition, she received 1st Place at the AAD 2024 Poster Award for her study on skin barrier health. Her work has also made her one of the most-read and cited authors in Allergy and Pediatric Dermatology in 2024, underscoring her impact and visibility in her field.

🌐 Impact and Influence

Through her extensive collaborations, Dr. Zhang has influenced clinical practices and regulatory frameworks worldwide. Her involvement in key study proposals and evidence generation initiatives has significantly impacted the medical community’s understanding of dermatological conditions. Her efforts in strategic planning, data generation, and cross-functional teamwork have positioned her as an influential figure in dermatology and immunology, particularly in advancing therapies that meet rigorous safety and efficacy standards.

🌱 Legacy and Future Contributions

Dr. Zhang’s legacy lies in her innovative approach to medical evidence generation and her unwavering commitment to patient-centered research. Her leadership in studies such as PEDISTAD and INFANTSTAD has set new standards for clinical research in dermatology and immunology. As she continues her work at Sanofi, Dr. Zhang’s contributions promise to expand the understanding and treatment of complex immunological conditions, impacting healthcare practices on a global scale.

Through her career, Dr. Zhang has exemplified excellence, dedication, and a strategic vision, ensuring her place as a respected leader in the pharmaceutical and clinical research sectors. Her ongoing work will undoubtedly continue to shape medical innovations and patient care improvements, leaving a lasting legacy in the fields of immunology and dermatology.

🎓Publication 

Efficacy and Tolerability of Delayed-release Dimethyl Fumarate in Black, Hispanic, and Asian Patients with Relapsing-Remitting Multiple Sclerosis: Post Hoc Integrated Analysis of DEFINE and CONFIRM

  • Authors   :Fox, R.J., Gold, R., Phillips, J.T., Zhang, A., Marantz, J.L.
  • Journal    :Neurology and Therapy
  • Year         :2017

Number Needed to Treat in Multiple Sclerosis Clinical Trials

  • Authors   : Okwuokenye, M., Zhang, A., Pace, A., Peace, K.E.
  • Journal    :Neurology and Therapy
  • Year         :2017

Comparative effectiveness using a matching-adjusted indirect comparison between delayed-release dimethyl fumarate and fingolimod for the treatment of multiple sclerosis

  • Authors   : Fox, R.J., Chan, A., Zhang, A., Edwards, M.R., Marantz, J.L
  • Journal    :Current Medical Research and Opinion
  • Year         :2017

Sustained Effect of Delayed-Release Dimethyl Fumarate in Newly Diagnosed Patients with Relapsing–Remitting Multiple Sclerosis: 6-Year Interim Results From an Extension of the DEFINE and CONFIRM Studies

  • Authors   :Gold, R., Giovannoni, G., Phillips, J.T., Zhang, A., Marantz, J.L.
  • Journal    :Neurology and Therapy
  • Year         :2016

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS

  • Authors   :Spelman, T., Kalincik, T., Jokubaitis, V., Trojano, M., Butzkueven, H.
  • Journal    :Neurology: Clinical Practice
  • Year         :2016

Assist Prof Dr. Hossam Hwihy|Immunotherapy |Best Researcher Award

Assist Prof Dr. Hossam Hwihy, Immunotherapy ,Excellence in Innovation Awards

Assist Prof Dr. Hossam Hwihy at Faculty of science Al-Azhar University,Egypt

PROFILE  

scopus

 

Early Academic Pursuits 🎓

Dr. Hossam Mohammed Sayed Hwihy, an Egyptian national born on September 9, 1985, embarked on his academic journey with a deep passion for marine biology and environmental sciences. He completed his B.Sc. in Science with a specialization in Marine Biology from Al-Azhar University, Cairo, in 2007. His early academic pursuits were driven by a keen interest in understanding the complex interactions within marine ecosystems and the impact of human activities on these delicate environments. This foundational knowledge paved the way for his subsequent research in marine pollution and aquaculture, fields in which he would later make significant contributions.

To further his expertise, Dr. Hwihy pursued a Master’s degree in Marine Pollution at Al-Azhar University, graduating in 2018. His research during this period focused on the detrimental effects of pollutants on marine life, particularly how they affect aquatic organisms at the cellular and biochemical levels. His academic journey continued with a Ph.D. in Marine Biology from the same institution, which he completed in 2021. His doctoral research was instrumental in deepening his understanding of marine ecosystems and their responses to environmental stressors.

Professional Endeavors 💼

Dr. Hwihy’s professional career is marked by his dedication to both teaching and research in the field of marine biology and aquaculture. Starting as a Teaching Assistant in Zoology at Al-Azhar University in 2016, he quickly established himself as an enthusiastic and knowledgeable educator. He was involved in teaching a range of courses including Aquaculture, Fish Biology, Marine Pollution, and Seafood Processing to undergraduate students. His teaching philosophy emphasizes the practical application of theoretical knowledge, which has been well-received by his students.

In December 2021, Dr. Hwihy was appointed as a Lecturer and Postdoctoral Researcher at the Faculty of Science and Education, Al-Azhar University, Cairo. In this role, he has continued to contribute to the academic community through his teaching and research. Additionally, he is a founding member of the Al-Azhar Aquaponic Experimental Farm, a pioneering project that integrates aquaculture with hydroponics to create a sustainable food production system. This initiative highlights his commitment to advancing sustainable practices in aquaculture.

Contributions and Research Focus 🔬

Dr. Hwihy’s research contributions span several critical areas within marine biology and aquaculture. His primary research interests include:

  1. Aquaponics Management Systems: Dr. Hwihy has been at the forefront of research into aquaponics, a sustainable farming technique that combines aquaculture (raising fish) with hydroponics (growing plants without soil). His work focuses on optimizing these systems to enhance yield production while minimizing environmental impact.
  2. Nanotechnology in Aquatic Applications: He is actively involved in studying the effects of various nanomaterials on aquatic ecosystems, particularly how these materials can be used to address environmental challenges in aquaculture, such as pollution and disease management.
  3. Climate Change and Molecular Responses: Dr. Hwihy’s research also delves into the impacts of climate change on marine life, particularly at the molecular level. He is investigating how changes in temperature and other environmental factors influence the genetic and physiological responses of marine organisms.
  4. Marine Bioactive Materials and Toxins: His work in this area focuses on the application of marine-derived compounds in managing fish diseases and addressing environmental issues in aquaculture. This research is critical for developing new strategies to enhance the sustainability of fish farming.
  5. Artificial Intelligence in Aquaculture: Dr. Hwihy is exploring the use of artificial intelligence (AI) to improve the management of aquaculture systems. His research aims to develop AI-based tools for monitoring water quality, predicting fish health, and optimizing feeding strategies.

Accolades and Recognition 🏆

Throughout his career, Dr. Hwihy has been recognized for his contributions to marine biology and aquaculture. He has presented his research at numerous conferences and workshops, sharing his insights with the global scientific community. Notable among these is his presentation at the 9th International Conference for Basic Sciences (ISCAZ) in 2017, where he discussed the lethal toxicity of Profenofos and Sesbania sesban on freshwater snails. His work in this area has been published, further establishing his reputation as a researcher of note.

Dr. Hwihy has also been a caller and participant in various workshops, including those focused on aquaponics, nanotechnology, and the application of artificial intelligence in scientific research. His involvement in these events reflects his commitment to continuous learning and knowledge dissemination.

Impact and Influence 🌍

Dr. Hwihy’s work has had a significant impact on the field of aquaculture and marine biology, particularly in Egypt. His research on aquaponics and sustainable aquaculture practices has the potential to revolutionize food production in regions facing water scarcity and environmental degradation. By integrating innovative technologies such as nanotechnology and AI into aquaculture, he is helping to pave the way for more resilient and efficient farming systems.

His contributions extend beyond academia, as he actively engages in community outreach through workshops and seminars aimed at educating the public and industry stakeholders about the benefits of sustainable aquaculture. His role as a founding member of the Al-Azhar Aquaponic Experimental Farm is particularly noteworthy, as it serves as a model for future aquaculture projects in Egypt and beyond.

Legacy and Future Contributions 🚀

As a leading figure in the field of aquaculture and marine biology, Dr. Hwihy’s legacy is one of innovation and sustainability. His research has laid the groundwork for future advancements in sustainable food production, particularly in arid regions where traditional farming methods are less viable. His work in nanotechnology and AI is likely to have far-reaching implications for the future of aquaculture, making it more efficient and environmentally friendly.

🎓Publication 

Threat of heavy metal pollutants and parasites to freshwater fish with special reference to their risk of cancer to humans in Egypt

  • Authors   :Afifi, M.A.M., Radwan, M., Abbas, M.M.M., Alabssawy, A.N., Khalaf-Allah, H.M.M.
  • Journal    :Aquaculture
  • Year         :2024

Biofloc biosecurity: A revolutionary paradigm in augmenting aquaculture health and resilience against Aeromonas hydrophila

    • Authors :Hwihy, H.M., Zeina, A.F., Abu Husein, M.S., El-Tabakh, M.A.M.
    • Journal   :Aquaculture and Fisheries
    • Year       : 2024

Evaluating of Pea Peels Meal as a Fishmeal alternative in Formulated Diet Ingredients of Oreochromis niloticus

UPLC/ESI/MS profiling of red algae Galaxaura rugosa extracts and its activity against malaria mosquito vector, Anopheles pharoensis, with reference to Danio rerio and Daphnia magna as bioindicators

  • Authors  :El-Tabakh, M.A.M., Elhawary, E.A., Hwihy, H.M., Bakr, N.A., Shehata, A.Z.I.
  • Journal   :Malaria Journal
  • Year        :   2023

DNA Barcoding and Sensitivity of Dengue Vector Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) Aquatic Stages to Different Insecticides with Reference to Non-Target Organisms, Danio rerio and Daphnia magna