Farha Naz | Drug Repurposing | Women Researcher Award

Dr. Farha Naz | Drug Repurposing | Women Researcher Award

Research Scientist at University of Virginia | United States

Dr. Farha Naz is a dynamic and accomplished structural biologist and immunologist, currently serving as a Research Scientist at the University of Virginia, USA. With a Ph.D. in Structural Biology from Jamia Millia Islamia, she has cultivated a distinguished research career focused on infectious diseases, host immunity, and vaccine development. Her postdoctoral work spans prestigious institutions including ICMR and UVA, and she has contributed to impactful translational research on Clostridioides difficile infection, tuberculosis, and host-pathogen interactions. Dr. Naz is also a frequent corresponding author and editorial contributor, demonstrating her leadership and scientific vision in global biomedical research.

Publication Profile 

Google Scholar

Education 

Dr. Farha Naz earned her Ph.D. in Structural Biology from Jamia Millia Islamia, New Delhi, graduating top of her batch in pre-PhD coursework. She completed her M.Sc. in Biotechnology in from Jamia Hamdard. Her B.Sc. from the University of Allahabad was marked by academic distinction, graduating. She completed her 12th and 10th at RDBIC, Allahabad. Her educational journey reflects academic excellence.

Experience 

Dr. Naz began her academic career as a Guest Faculty at the Centre of Bioinformatics, University of Allahabad. She later served as a Temporary Assistant Professor at SHUATS, Allahabad. she held a prestigious ICMR-Centenary Postdoctoral Fellowship at the National Institute of Pathology-ICMR in New Delhi. She then joined the University of Virginia as a Postdoctoral Research Associate in the Division of Infectious Diseases and International Health. Since February  she has been a Research Scientist in the same department, contributing to cutting-edge immunological and translational research in infectious diseases.

Awards and Honors 

Dr. Farha Naz has received multiple academic honors throughout her career. She was awarded the Junior Scientist Award by the Council of Science & Technology, U.P. She graduated as the Faculty Topper of her B.Sc. batch. She has qualified prestigious national fellowships and exams including the CSIR-UGC Fellowship in December, GATE in February, and the CSIR-UGC NET in June. These achievements highlight her consistent academic performance and her early recognition as a promising scientific talent. Her excellence continues through her high-impact research outputs and leadership roles in translational science.

Research Focus 

Dr. Naz’s research centers on host-pathogen interactions, mucosal immunology, and vaccine development, particularly against Clostridioides difficile and Mycobacterium tuberculosis. She investigates the mechanisms by which pathogens evade host immunity and how immune modulation can be leveraged for therapeutic interventions. Her work explores innate immune responses, cytokine signaling, GPCR modulation, and the role of sphingolipids in infection. She has contributed significantly to understanding vaccine adjuvants, humoral responses in recurrent infections, and therapeutic strategies involving immune and nervous system crosstalk. Her translational research aims to advance precision immunotherapy and infectious disease control globally.

Publication Top Notes

Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression

Microtubule affinity-regulating kinase 4: structure, function, and regulation

Elucidation of dietary polyphenolics as potential inhibitor of microtubule affinity regulating kinase 4: in silico and in vitro studies

Designing new kinase inhibitor derivatives as therapeutics against common complex diseases: structural basis of microtubule affinity-regulating kinase 4 (MARK4) inhibition

PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4

Battling COVID-19 pandemic: sphingosine-1-phosphate analogs as an adjunctive therapy?

Cloning, Expression, Purification and Refolding of Microtubule Affinity-Regulating Kinase 4 Expressed in Escherichia coli

Ubiquitin-associated domain of MARK4 provides stability at physiological pH

Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro

Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages

Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays

Human microtubule affinity-regulating kinase 4 is stable at extremes of pH

Dongshan Zhang | Drug Discovery and Development | Best Researcher Award

Prof. Dr. Dongshan Zhang | Drug Discovery and Development | Best Researcher Award

Director at nd Xiangya Hospital | Central South University | China

Prof. Dr. Dongshan Zhang is a highly respected Chief Physician and Professor at Central South University, China. A postdoctoral fellow trained in the United States, he is a PhD supervisor and a recipient of China’s National Top Talent Program for Science and Technology Leaders. As Director of both the Institute of Emergency and Difficult Diseases and the Clinical Medical Research Center for Acute Organ Injury and Repair, he leads cutting-edge medical research. With over 46 SCI publications and multiple patents, his work in acute kidney injury has earned him prestigious awards and international acclaim.

Publication Profile 

Education 

Prof. Zhang pursued rigorous academic training in China and completed his postdoctoral fellowship in the United States, gaining advanced insights into nephrology and translational medicine. He earned his medical and doctoral degrees from top Chinese medical universities, where he laid the foundation for his expertise in acute organ injury. His exposure to international research environments shaped his multidisciplinary approach. Now, as a PhD supervisor, he mentors future scientists and clinicians, promoting global research collaborations and innovation in clinical nephrology and emergency medicine.

Experience 

Prof. Zhang currently serves as Chief Physician and Professor at Central South University, where he is also a Distinguished Shenghua Scholar Professor. He directs two major research institutes: the Institute of Emergency and Difficult Diseases and the Clinical Medical Research Center for Acute Organ Injury and Repair in Hunan Province. Over his career, he has led four NSFC-funded national research projects and served as Associate Editor for top journals. His commercialized patents and extensive publication record reflect his commitment to translational research and clinical excellence.

Awards 

Prof. Zhang’s outstanding contributions have earned him the First Prize of the Natural Science Award of Hunan Province. He has been recognized as a National Top Talent in Science and Technology, awarded for his pioneering work in nephrology and acute organ injury. His research papers have graced the covers of leading journals, affirming his global impact. As a Distinguished Shenghua Scholar Professor and active editorial board member, he continues to shape scientific thought and innovation. His accolades highlight both clinical expertise and trailblazing research excellence.

Research Focus 

Prof. Zhang’s primary research centers on Acute Kidney Injury (AKI), encompassing mechanisms of injury, repair, and translational approaches to therapy. His work explores inflammation, apoptosis, and molecular pathways involved in kidney damage. He leads interdisciplinary teams to develop innovative drug targets and biomarkers, bridging basic science and clinical application. With support from multiple NSFC grants, his lab integrates in vivo models, molecular profiling, and AI-driven analytics to advance precision nephrology. His research contributes to improving prognosis and treatment in critical care settings.

Publication Top Notes

Title: PRDM16 acts as a homeostasis regulation factor to suppress the transition of AKI to CKD via upregulation of eukaryotic initiation factor 6
Journal: Cellular and Molecular Life Sciences
Year: 2025

Title: PRDM16 suppresses pyroptosis to attenuate the progression of AKI caused by rhabdomyolysis via upregulation of USP10
Journal: Cellular and Molecular Life Sciences
Year: 2025

Title: Mmu_circ_0005698/hsa_circ_0085381/miR-532-3p/Arhgdib axis mediates the ischemic progression of acute kidney injury
Journal: International Immunopharmacology
Year: 2025

Title: Recombinant monoclonal antibody siltartoxatug versus plasma-derived human tetanus immunoglobulin for tetanus: a randomized, double-blind, active-controlled, phase 3 trial
Journal: Nature Medicine
Year: 2025

Title: Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer
Journal: International Journal of Biological Sciences
Year: 2025

Title: PRDM16 suppresses ferroptosis to protect against sepsis-associated acute kidney injury by targeting the NRF2/GPX4 axis
Journal: Redox Biology
Year: 2024

Title: NRF1-induced mmu_circ_0001388/hsa_circ_0029470 confers ferroptosis resistance in ischemic acute kidney injury via the miR-193b-3p/TCF4/GPX4 axis
Journal: Life Sciences
Year: 2024

Title: Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury
Journal: Not specified
Year: Not specified

Conclusion

Prof. Dr. Dongshan Zhang is an outstanding candidate for the Research for Best Researcher Award, possessing an exceptional track record in acute organ injury research, prolific publication output, successful grant leadership, and tangible innovations through patents. His blend of academic excellence, clinical relevance, and translational success makes him a model researcher with substantial contributions to global health and kidney disease research. With minor expansion in global collaborations and strategic outreach, his impact can become even more internationally transformative.