Henryk Mazurek | Precision Medicine | Best Researcher Award

Henryk Mazurek | Precision Medicine | Best Researcher Award

Prof. Henryk Mazurek, National Tuberculosis and Lung Diseases Institute, Department of Pneumonology and Cystic Fibrosis, Poland

Prof. Henryk Mazurek is a distinguished pulmonologist, allergologist, and pediatrician specializing in pediatric pulmonology and respiratory diseases. He serves as the Head of the Department of Pneumonology and Cystic Fibrosis at the National Tuberculosis and Lung Diseases Institute, Poland 🇵🇱. With over 60 original research articles and extensive contributions to medical literature 📚, he has significantly advanced the understanding of chronic respiratory diseases, asthma, and cystic fibrosis. A member of esteemed scientific societies 🌍, he actively collaborates internationally and leads impactful research projects. His work in AI-assisted diagnostics and pulmonary care is shaping the future of respiratory medicine. 🚀

Publication Profile

Scopus

Professional Background

Professor Henryk Mazurek is a distinguished pulmonary disease specialist, allergologist, pediatrician, and pediatric pulmonology expert 🩺. He completed postgraduate studies in respiratory pathophysiology in France 🇫🇷 and holds the title of Full Professor in medical and health sciences 🎓. As an academic, he teaches nursing and postgraduate medical training in pediatrics, allergology, and lung diseases. He has authored and co-authored over 60 original articles, 100+ textbook chapters, and numerous scientific publications 📚. A sought-after lecturer, he shares his expertise at medical conferences, educating physicians and healthcare professionals worldwide 🌍.

Memberships

Prof. Henryk Mazurek is an esteemed member of several prestigious scientific organizations, fostering international collaboration in respiratory medicine 🌍🫁. He holds a combined membership in the European Respiratory Society (ERS) / Polish Respiratory Society, along with memberships in the Polish Society of Allergology and the Polish Society of Pediatric Pulmonology, where he is an honorary member 🎖️. For many years, he contributed to the Scientific Council of the Institute of Tuberculosis and Lung Diseases in Warsaw 🏥. Additionally, he served on the Main Boards of the Polish Society of Allergology (2015-2021) and the Polish Society of Cystic Fibrosis (2014-2018) 📚.

Industry Projects

Prof. Henryk Mazurek has actively contributed to over 50 industry-sponsored clinical trials, showcasing his expertise in applied research 🔬. His consultancy work plays a crucial role in bridging academic research with real-world healthcare applications, particularly in advancing treatment strategies for cystic fibrosis 🫁. Through his collaborations with pharmaceutical and medical device companies 💊🩺, he has successfully translated research findings into clinical practice, improving patient outcomes. His dedication to innovation and evidence-based solutions continues to shape the future of respiratory medicine, reinforcing his impact on both academia and industry. 🌍

Research Focus

Prof. Henryk Mazurek’s research primarily focuses on respiratory diseases 🫁, particularly in cystic fibrosis 🧬, pediatric pulmonology 👶, and ventilator-associated pneumonia 🏥. His work explores innovative AI-facilitated home monitoring 🤖 for cystic fibrosis, childhood asthma treatments 🌬️, and the effects of medications like Gabapentin on post-operative pain 💊. He has also studied risk factors for pneumonia 🦠 and strategies for its prevention in ventilated patients. His expertise lies in pulmonary infections, inflammatory biomarkers, and personalized medicine 🧑‍⚕️. His contributions significantly impact respiratory healthcare, enhancing diagnostic and therapeutic approaches for both pediatric and adult patients.

Publication Top Notes

AI-facilitated home monitoring for cystic fibrosis exacerbations across pediatric and adult populations

Childhood asthma treatment based on indirect hyperresponsiveness test: Randomized controlled trial

The Effects of Gabapentin on Post-Operative Pain and Anxiety, Morphine Consumption and Patient Satisfaction in Paediatric Patients Following the Ravitch Procedure—A Randomised, Double-Blind, Placebo-Controlled, Phase 4 Trial

Risk Factors and Protective Factors against Ventilator-Associated Pneumonia—A Single-Center Mixed Prospective and Retrospective Cohort Study

Automatic continuous control of cuff pressure and subglottic secretion suction used together to prevent pneumonia in ventilated patients—a retrospective and prospective cohort study

Chronic bacterial pulmonary infections in advanced cystic fibrosis differently affect the level of sputum neutrophil elastase, IL-8 and IL-6

Assoc Prof Dr. Muhammad Raza| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Razal Kotaska| Medicinal Chemistry|Best Researcher Award

Assoc Prof Dr. Muhammad Raza at University of Gujrat,Pakistan

PROFILE  

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Early Academic Pursuits 🎓

Dr. Muhammad Asam Raza embarked on his academic journey with a strong foundation in the natural sciences. After completing his F.Sc. from the Board of Intermediate and Secondary Education, Gujranwala in 1998, he pursued a B.Sc. in Zoology, Botany, and Chemistry from the University of Punjab, Lahore. His profound interest in chemistry led him to continue his academic endeavors with an M.Sc. in Chemistry from the same institution, where his research centered on “Production of xylanases and cellulases in bioreactor by using Chaetomium thermophile.”

Dr. Raza’s pursuit of higher education took him to GC University, Lahore, where he earned both his M.Phil. and Ph.D. degrees in Chemistry. His M.Phil. research focused on the “Phytochemical and antioxidant screening of Mimusops elengi,” while his Ph.D. dissertation was centered on the “Extraction, structure elucidation, and microbial transformation of protease inhibitors from medicinal plants.” These early research topics highlight his passion for bioactive compounds and natural product chemistry, setting the stage for a career rich in scientific exploration.

Professional Endeavors 👨‍🏫

Dr. Raza’s academic and research career took off when he joined the University of Gujrat in 2011 as an Assistant Professor in the Department of Chemistry. Over the years, he contributed extensively to teaching and research at the institution, shaping the academic futures of numerous students. His dedication and excellence in the field of chemistry led to his promotion to Associate Professor in December 2020.

In addition to his role as a professor, Dr. Raza has held various administrative responsibilities at the University of Gujrat, including serving as the coordinator of the Four Year Degree Program in Chemistry, time table in-charge, and head examiner for the B.Sc./B.S. Program. His involvement in organizing industrial and study tours has further enriched the academic experiences of students, giving them a practical understanding of their field of study.

Contributions and Research Focus 🔬

Dr. Raza’s research portfolio is vast, focusing primarily on bioactive compounds, their purification, synthesis, and characterization. His expertise in chromatographic techniques, such as Thin Layer Chromatography (TLC), Column Chromatography, and High-Performance Liquid Chromatography (HPLC), has led to significant breakthroughs in the purification of bioactive compounds. He is also proficient in Gas Chromatography-Mass Spectrometry (GC-MS), enabling him to identify volatile compounds and elucidate the structures of synthesized and natural products.

His research interests also encompass microbial transformation, enzyme inhibition, antioxidant studies, and kinetic studies of various reactions. He has explored both natural and synthetic compounds for their antimicrobial and enzyme inhibition properties, significantly contributing to the field of medicinal chemistry. Additionally, Dr. Raza’s work on the production and characterization of xylanases and cellulases from fungal cultures demonstrates his expertise in enzyme technology, which holds potential for industrial applications.

Docking studies, using different software, have also been a significant focus in Dr. Raza’s research. This computational approach to studying molecular interactions has opened new avenues in drug design and development, further enhancing his contributions to the chemistry of biologically active molecules.

Accolades and Recognition 🏆

Throughout his career, Dr. Muhammad Asam Raza has received numerous accolades, reflecting his excellence in both academic and research fields. He was awarded a Merit Scholarship in 1997 from the District Council of Hafizabad, which was an early indicator of his potential. Later, he received the Indigenous PhD 5000 Fellowship Program from the Higher Education Commission (HEC) of Pakistan, a prestigious scholarship that supported his doctoral studies. Dr. Raza’s contributions to research were also acknowledged by the Pakistan Council for Science and Technology (PCST) with Research Productivity Awards in 2012 and 2013.

Further recognition of his expertise came when Dr. Raza was approved as a Ph.D. supervisor by the HEC, allowing him to mentor and guide future researchers in their academic pursuits. Additionally, he secured a research project worth half a million rupees from the HEC, demonstrating his ability to attract significant funding for his research endeavors.

Impact and Influence 🌍

Dr. Raza’s impact extends beyond the classroom and laboratory. His active participation in organizing national and international workshops, seminars, and symposiums has significantly contributed to the dissemination of knowledge in the scientific community. He has been instrumental in hosting events such as the “Two Days Interdisciplinary National Workshop on Chromatography & Mass Spectrometry” and the “Two Days International Symposium on Developments in Contemporary Chemistry” at the University of Gujrat.

His administrative roles have also been influential, particularly his contributions as a member of various departmental committees, including the Departmental Doctoral/MPhil Program Committee (DDMPC) and the Purchase Committee (NRPU). Dr. Raza’s participation in such committees highlights his commitment to improving the academic and research infrastructure at the University of Gujrat.

Furthermore, Dr. Raza’s work as a reviewer for scientific journals and project evaluator for research proposals under the NRPU has contributed to maintaining the standards of scientific inquiry in Pakistan. His expertise is frequently sought in assessing research proposals and reviewing academic papers, ensuring the advancement of chemistry research in the country.

Legacy and Future Contributions 🌱

Dr. Muhammad Asam Raza’s contributions to the field of chemistry, both in terms of research and teaching, have left a lasting legacy at the University of Gujrat and beyond. His commitment to advancing knowledge in bioactive compounds, enzyme inhibition, and molecular docking studies is not only reflected in his research but also in the numerous students he has mentored over the years.

Looking forward, Dr. Raza is poised to continue making significant contributions to the field of chemistry, particularly in the areas of natural product chemistry, enzyme technology, and computational drug design. His future work will likely focus on the synthesis and characterization of biologically active compounds, with potential applications in pharmaceuticals, agriculture, and biotechnology.

Dr. Raza’s legacy will undoubtedly be defined by his passion for chemistry, his dedication to teaching, and his tireless pursuit of scientific excellence, which will continue to inspire future generations of researchers.

🎓Publication 

Acetylcholine and butyrylcholine esterase inhibitory potential of newly synthesized halogenated compounds: In vitro, in silico and MD simulation

  • Authors   : emanur Yesilbağ; Muhammad Asam Raza; Zeshan Ali Sandhu; Umme Farwa; Emine Berrin Poyraz;
  • Journal    :Molecular Structure
  • Year         :2025

Advances in the Optimization of Fe Nanoparticles: Unlocking Antifungal Properties for Biomedical Applications

  • Authors   : Sandhu, Z.A.; Raza, M.A.; Alqurashi, A.; Sajid, S.; Ashraf, S.; Imtiaz, K.; Aman, F.; Alessa, A.H.; Shamsi, M.B.; Latif, M.
  • Journal    :Pharmaceutics
  • Year         :2024

Association of APO B gene polymorphisms with the development of myocardial infarction in Pakistani population

  • Authors   : Arshad, M.; Iqbal, R.; Raza, M.; Bashir, R.; Ahmed, T.; Parveen, A.
  • Journal    :Gene
  • Year         :2024

Beyond graphene: exploring the potential of MXene anodes for enhanced lithium–sulfur battery performance

  • Authors   : Zeshan Ali Sandhu; Kainat Imtiaz; Muhammad Asam Raza; Adnan Ashraf; Areej Tubassum; Sajawal Khan; Umme Farwa; Ali Haider Bhalli; Abdullah G. Al-Sehemi
  • Journal    :RSC Advances
  • Year         :2024

Biomedical properties, characterization of seaweeds species and antimicrobial activity,Propriedades biomédicas, caracterização de espécies de algas marinhas e atividade antimicrobiana

  • Authors   : Rizwan, S.; Saleem, M.; Hassan, H.U.; Raza, M.A.; Kanwal, R.; Kabir, M.; Ghaffar, R.A.; Fadladdin, Y.A.J.; Rafiq, N.; Matin, A. et al.
  • Journal    :Brazilian Journal of Biology
  • Year         :2024

Assoc Prof Dr. Karel Kotaska| Precision Medicine |Best Researcher Award

Assoc Prof Dr. Karel Kotaska|Precision Medicine|Best Researcher Award

Assoc Prof Dr. Karel Kotaska at University Hospital Motol,Czech Republic

PROFILE  

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🎓 Early Academic Pursuits

Kotaška’s academic journey began at the Sladkovského High School in Prague, where he completed his secondary education in 1992. Following this, he embarked on an educational path that laid the foundation for his career in biochemistry. In 1997, he graduated from the Institute of Chemical Technology in Prague, earning a Dipl. Ing. in Chemistry Engineering, specializing in Biomedical Engineering. His thirst for knowledge led him to pursue postgraduate studies at the 2nd Medical Faculty of Charles University, Prague, where he specialized in Biochemistry and Pathobiochemistry, culminating in a Ph.D. in 2003. His doctoral research and thesis defense were pivotal moments in shaping his future career as a leading figure in biochemistry.

🏢 Professional Endeavors

Kotaška’s professional career has spanned over two decades, beginning in 2002 at the Department of Medical Chemistry and Clinical Biochemistry at the University Hospital Motol, one of the largest medical facilities in the Czech Republic. As a research scientist and specialist, he quickly became an integral part of the team, contributing significantly to research projects and clinical laboratory functions. In 2015, Kotaška was appointed Associate Professor in Medical Chemistry and Clinical Biochemistry at the 2nd Medical Faculty of Charles University, further solidifying his standing as an expert in his field. His role expanded into quality management, becoming an auditor and overseeing laboratory processes to ensure adherence to ISO standards and good laboratory practices.

🔬 Contributions and Research Focus

Kotaška’s research interests are broad and impactful, covering various aspects of biochemistry and clinical diagnostics. His primary research focuses on the role of natriuretic peptides in cardiovascular diseases, a field critical for advancing the understanding and treatment of heart-related conditions. He has also made significant strides in investigating biomarkers associated with cardiovascular, neurological, inflammatory, and tumor diseases.

In addition to his contributions to molecular genetics, where he has explored genetic variants linked to diseases, Kotaška is well-versed in laboratory management and external quality control. He has been involved in the harmonization and standardization of laboratory practices, ensuring that diagnostics adhere to global standards. His work in urinalysis and infrared spectroscopy has also pushed forward diagnostic capabilities in clinical biochemistry.

🏆 Accolades and Recognition

Kotaška’s impressive career has not gone unnoticed. He has received numerous grant awards for his research, including projects funded by the Grant Agency of the Ministry of Health (MH) and Charles University. His studies have ranged from investigating biomarkers for organ failure to exploring the molecular biology of neurofibromatosis and cathepsin B activity in bladder carcinoma.

Notably, his project on the biological behavior of urological malignancies, which involved long-term monitoring of tissue, serum, and urine samples, stands out as a pioneering effort in the field of cancer research. Additionally, his ongoing work since 2021 on the effect of combined treatments in chronic heart failure in animal models has further contributed to advancing therapeutic approaches.

🌍 Impact and Influence

Beyond his laboratory work, Kotaška has made substantial contributions to academia and clinical education. Since 2008, he has been involved in teaching postgraduate students and has served as a lecturer at several institutions, including the Czech Technical University, where he taught biomedical engineering and laboratory techniques until 2023. As a member of the education team in postgraduate doctoral studies, he has mentored countless students, helping shape the next generation of biochemists and medical professionals.

Kotaška’s influence extends to his role as a reviewer for several prestigious biomedical journals, such as the Central European Journal of Biology, Open Heart Journal, and Diagnostics. His expertise in statistical methods, including regression analysis, survival analysis, and data evaluation, has positioned him as a thought leader in clinical diagnostics.

📚 Publications and Peer Review

With 66 peer-reviewed publications and 12 book chapters to his name, Kotaška’s work has been widely recognized and cited in the scientific community. His publications span critical topics in clinical biochemistry, genetic research, and molecular diagnostics. His H-index of 10 reflects the significant impact of his research, with 317 citations from scholars and professionals in related fields. His commitment to advancing clinical diagnostics and biochemistry is evident in his body of work, which continues to inform and guide research in these areas.

🏅 Legacy and Future Contributions

Kotaška’s legacy is rooted in his contributions to clinical biochemistry and medical diagnostics. His work on improving diagnostic efficiency, standardizing laboratory procedures, and exploring biomarkers in diseases has set a benchmark in the medical field. As a corresponding member of prominent international organizations, such as the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and the International Federation of Clinical Chemistry (IFCC), his influence extends beyond the Czech Republic to the global scientific community.

Karel Kotaška’s future contributions are likely to focus on further enhancing diagnostic tools and treatment methods, particularly in the fields of cardiovascular diseases and cancer research. His ongoing work in investigating the effects of innovative therapeutic treatments for chronic heart failure demonstrates his commitment to improving patient outcomes. Additionally, his leadership in laboratory standardization efforts will continue to shape the practices of clinical laboratories worldwide, ensuring that diagnostics remain accurate, efficient, and globally harmonized.

🌟 Conclusion

Karel Kotaška’s career is a testament to his dedication to advancing medical science and education. His multifaceted contributions as a researcher, educator, and laboratory manager have left a lasting impact on the fields of biochemistry and clinical diagnostics. His work continues to influence both the scientific community and clinical practices, ensuring his legacy as a leading figure in medical chemistry and clinical biochemistry for years to come.

🎓Publication 

Polycyanoacrylate (super glue) as bladder concretion in a patient after bilateral inguinal hernioplasty

  • Authors   : Karel Kotaška; Milan Polák; Antonín Brisuda; Richard Průša
  • Journal    : Annals of Clinical Biochemistry
  • Year         :2020