Dr.Careen Liza Pakyntein, Pharmaceutical Analysis ,Best Researcher Award

Dr.Careen Liza Pakyntein, Pharmaceutical Analysis ,Best Researcher Award

Dr.Careen Liza Pakyntein, at NORTH EASTERN HILL UNIVERSITY,India

Author Profile

Skills⚡

  • 🌿 Phytochemical Profiling
  • ⚗️ Gas Chromatography
  • 🧪 Flash Chromatography
  • 🧬 Thin Layer Chromatography
  • 💉 High-Performance Liquid Chromatography (HPTLC)
  • 🧫 Conventional Polymerase Chain Reaction (PCR)
  • 🧬 Real-Time Polymerase Chain Reaction (RT-PCR)
  • ⚡ Electrophoresis Techniques: SDS-PAGE, PFGE
  • 🧬 DNA/RNA/Protein Isolation
  • 🧬 Western Blotting
  • 🧫 Biochemical Analysis
  • 🐭 Mice Handling
  • 🧬 ADME-TOX Profiling
  • 🔬 Immunohistochemistry
  • 🔬 Microscopy
  • 🧫 Microbiology
  • 🧫 Cell Culture

Experience🧑‍🔬

  • Project Scientist-
    • IBSD, Manipur (March 2024 – Present)
    • Duties: Sample screening and analysis, data collection and interpretation, data documentation, preparation of reports, presentations, project deliverables.
  • Project Associate-I 
    • Division of Animal and Fisheries Sciences, ICAR-RC NEH, Umiam (December 2021 – June 2023)
    • Duties: Sample screening and analysis, data collection and interpretation, data documentation, preparation of reports, presentations, project deliverables.
  • Research Scholar 
    • Department of Biochemistry, NEHU, Shillong (February 2017 – November 2021)
    • Duties: Drafting research proposals, research data collection, analysis, documentation, interpretation, paper presentation at national and international conferences, paper writing and publication, supervised and mentored PG students for dissertation projects.

Education📚

  •  Ph.D. in Biochemistry
    • North-Eastern Hill University, Shillong (August 2023)
  •  M.Sc. in Biochemistry
    • North-Eastern Hill University, Shillong (August 2016)
  •  B.Sc. in Biochemistry
    • St. Anthony’s College, Shillong (June 2014)
  •  AISSCE (Science)
    • Kendriya Vidyalaya Laitkor Peak, Shillong (May 2011)
  •  SSLC
    • Hill Crest Higher Secondary School, Shillong (May 2009)

Publications 📄

  1. Syiem, A.B., Pakyntein, C.L., Syiem, D., Thabah D. 
    • “Amelioration of carbohydrate and fat metabolism by Houttuynia cordata and Hypochaeris radicata in alloxan-induced diabetic mice.” International Journal of Pharmacological Research (2022); 12(5): e5743.
  2. Sunn, S.E., Syiem, D., Pakyntein, C.L. 
    • “Amelioration of altered adipokines expression and serine/threonine phosphorylation of IRS1 in alloxan-induced diabetes by Potentilla fulgens and its phytochemical constituents.” GSC Biological and Pharmaceutical Sciences (2021); 17(03): 144–152.
  3. Pakyntein, C.L., Syiem, D., Thabah D., Sunn, S.E. 
    • “Antioxidant, anti-inflammatory and antihyperglycemic activity of aqueous and methanolic extract of Houttuynia cordata: an in vitro and in vivo study.” GSC Biological and Pharmaceutical Sciences (2021); 16(03): 145–154.
  4. Saio, V., Syiem, D., Sharma, R., Pakyntein, C.L. 
    • “Dichloromethane extract of Potentilla fulgens wall. Ex. Sims ameliorates alloxan-induced oxidative stress and inflammatory responses in mice.” Clinical Phytoscience (2021); 7:6.
  5. Thabah, D., Syiem, D., Pakyntein, C.L., Banerjee, S., Kharshiiing, C.E., Bhattacharjee, A. 
    • “Potentilla fulgens upregulate GLUT4, AMPK, AKT and insulin in alloxan-induced diabetic mice: an in vivo and in silico study.” Archives of Physiology and Biochemistry (2021); 129(5): 1071-1083.
  6. Wankhar, W., Syiem, D., Pakyntein, C.L., Thabah, D., Sunn S.E. 
    • “Effect of 5-HT2C receptor agonist and antagonist on chronic unpredictable stress (CUS) – Mediated anxiety and depression in adolescent Wistar albino rat: Implicating serotonin and mitochondrial ETC-I function in serotonergic neurotransmission.” Behavioural Brain Research (2020); 393: 112780.

 

🎓Publication Top Noted:

Paper Title : Potentilla fulgens Upregulate GLUT4, AMPK, AKT, and Insulin in Alloxan-Induced Diabetic Mice: An In Vivo and In Silico Study 🧬📊
    • Co-Authors: Syiem, D., Pakyntein, C.L., Kharshiing, C.E., Bhattacharjee, A.
    • Journal: Archives of Physiology and Biochemistry
    • Year: 2023
    • Summary: This study investigates the potential of Potentilla fulgens in regulating key metabolic pathways in diabetic mice, highlighting its ability to upregulate important proteins and enzymes involved in glucose metabolism.
  • Paper Title :Effect of 5-HT2C Receptor Agonist and Antagonist on Chronic Unpredictable Stress (CUS) – Mediated Anxiety and Depression in Adolescent Wistar Albino Rat: Implicating Serotonin and Mitochondrial ETC-I Function in Serotonergic Neurotransmission 🧠🔬
    • Co-Authors: Wankhar, W., Syiem, D., Pakyntein, C.L., Sunn, S.E.
    • Journal: Behavioural Brain Research
    • Year: 2020
    • Summary: This research explores the role of 5-HT2C receptors in anxiety and depression caused by chronic unpredictable stress, emphasizing the connection between serotonergic neurotransmission and mitochondrial function.