Prof. Dr. Galal Elgemeie | Medicinal Chemistry | Best Researcher Award

Helwan University | Egypt

Prof. Elgemeie stands as a distinguished figure in the field of organic and medicinal chemistry, with a research career deeply rooted in the development and mechanistic understanding of organic reactions and their applications in synthesizing antimetabolic agents. His scholarly pursuits bridge fundamental chemistry with biomedical innovation, particularly in the discovery of novel therapeutic compounds aimed at combating cancer and viral diseases. Through his extensive academic contributions, he has established a legacy of excellence that continues to inspire scientists and researchers globally.An internationally recognized scientist, Prof. Elgemeie was elected as a member of the Scientific Board of the International Basic Sciences Programme (IBSP) under UNESCO in Paris, France, reflecting his global influence and leadership in advancing the chemical sciences. His postdoctoral experiences across Germany, the United States, and England—supported by prestigious foundations such as the Alexander von Humboldt Foundation, the Fulbright Program, and the British Council—shaped his multidisciplinary expertise and broadened his research collaborations across continents.Prof. Elgemeie’s innovative research has led to numerous impactful projects, including the design and synthesis of novel epigenetic small molecules and antimetabolites in collaboration with the Institute of Medicinal Chemistry, Düsseldorf University. His pioneering work in developing sofosbuvir analogues for treating hepatitis C virus (HCV) and hepatocellular carcinoma among Egyptian patients demonstrates his commitment to translating scientific discovery into therapeutic applications with real-world benefits.His publication record is exceptional, with over 270 papers indexed in international databases such as Scopus, and his scientific influence is further underscored by a significant citation index. He has authored influential scientific books with leading publishers like Elsevier, offering comprehensive insights into cancer metabolism and heterocyclic chemistry. Prof. Elgemeie also holds several patents in process, reflecting his drive to innovate beyond academia and contribute to industry-based advancements in medicinal chemistry.Serving as an editorial board member for prominent journals including Current Microwave Chemistry, he continues to guide the global scientific dialogue in his field. His collaborations span several institutions worldwide, reinforcing his reputation as a bridge between Egyptian and international research communities.Beyond research, Prof. Elgemeie has played a vital role in educational reform and academic development across Egypt and the Arab region. He has supervised multiple cooperative projects with the European Community under the TEMPUS programme, contributing to the restructuring of higher education and aligning it with international standards. These initiatives have significantly advanced institutional capacity and innovation within Mediterranean and Arab universities.

Profile: Orcid

Featured Publications

Azzam, R. A., Seif, M. M., El-Demellawy, M. A., & Elgemeie, G. H. (2025). Novel 2-substituted benzothiazole derivatives: Synthesis, in vitro and in silico evaluations as potential anticancer agents. RSC Advances.

Elgemeie, G. H., Fathy, N. M., & Shaarawi, S. I. (2024). Naphthyl cyanoketene N, S-acetals in glycoside synthesis: A new preparative route to a new class of N-naphthylcyanoacrylamide thioglycosides and their conversions to naphthyl–pyrazole hybrids. Nucleosides, Nucleotides & Nucleic Acids.

Abu-Zaied, M. A., Nawwar, G. A., & Elgemeie, G. H. (2024). Novel synthesis of a new class of substituted S-glycosylisothiourea derivatives and their conversion to 5-amino-1,2,4-triazoles. Synthetic Communications.

Metwally, N. H., Elgemeie, G. H., & Fahmy, F. G. (2023). Synthesis and biological evaluation of benzothiazolyl-pyridine hybrids as new antiviral agents against H5N1 bird flu and SARS-CoV-2 viruses. ACS Omega.

Abdallah, A. E. M., Abdel-Latif, S. A., & Elgemeie, G. H. (2023). Novel fluorescent benzothiazolyl-coumarin hybrids as anti-SARS-COVID-2 agents supported by molecular docking studies: Design, synthesis, X-ray crystal structures, DFT, and TD-DFT/PCM calculations. ACS Omega.

Ahmed, E. A., Elgemeie, G. H., & Azzam, R. A. (2023). Synthesis of new sulfapyrimidine and pyrazolo[1,5-a]pyrimidine derivatives. Synthetic Communications.

Khedr, M. A., Zaghary, W. A., Elsherif, G. E., Azzam, R. A., & Elgemeie, G. H. (2023). Purine analogs: Synthesis, evaluation and molecular dynamics of pyrazolopyrimidines-based benzothiazole as anticancer and antimicrobial CDK inhibitors. Nucleosides, Nucleotides & Nucleic Acids.