Ketan Ruparelia | Cancer Research | Research Excellence Award

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Research Excellence Award

Ketan Ruparelia — De Montfort University, United Kingdom

Ketan Ruparelia
Affiliation De Montfort University
Country United Kingdom
Scopus ID 6506888701
Documents 39
Citations 1,939
h-index 20
Subject Area Cancer Research
Event International Top Pharmaceutical Awards
ORCID 0000-0002-4091-2878

Ketan Ruparelia is a researcher affiliated with De Montfort University in Leicester, United Kingdom. His documented research works include studies spanning pharmaceutical and cancer-related research, including drug-delivery systems, anticancer compounds, phytochemical analysis, and medicinal chemistry. The available research record provides evidence of publications involving chemotherapy-related nanocarriers, synthetic resveratrol analogues, plant secondary metabolism, and flavone-based enzyme inhibition. These works provide a scholarly basis for considering his profile within pharmaceutical research and cancer-focused scientific activity. [1]

Abstract

Ketan Ruparelia’s documented research profile is associated with pharmaceutical and biomedical research, with particular relevance to cancer research, drug delivery, phytochemical investigation, and anticancer compound development. The available ORCID record lists five research works and identifies De Montfort University as his employment affiliation. [1]

Keywords

Ketan Ruparelia, pharmaceutical research, cancer research, drug delivery, nanomedicine, siRNA delivery, multidrug-resistant cancer, chemotherapy, mesoporous silica nanoparticles, anticancer compounds, resveratrol analogues, medicinal chemistry, phytochemical analysis, plant secondary metabolism, flavones, tyrosinase inhibitors, pharmaceutical biotechnology, International Top Pharmaceutical Awards.

Introduction

Pharmaceutical research increasingly combines medicinal chemistry, drug-delivery engineering, molecular biology, and natural-product investigation to address complex therapeutic challenges. Ruparelia’s documented works intersect several of these areas, particularly through research involving anticancer compounds and pharmaceutical delivery technologies. [1][3]

Research Profile

The ORCID record identifies Ketan Ruparelia and associates the profile with De Montfort University in Leicester, Leicestershire, United Kingdom. The employment entry specifies the position of Senior Technician in Health & Life Sciences, while the record also lists five works with Crossref-linked publication information. The supplied bibliometric profile reports 39 documents, 1,939 citations, and an h-index of 20, with Cancer Research identified as the principal subject area. [1]

Research Contributions

A central contribution documented in the available record concerns pharmaceutical nanotechnology and targeted nucleic-acid delivery. The 2025 European Journal of Pharmaceutics and Biopharmaceutics article examines electrosprayed core-shell polyethyleneimine and phospholipid-coated mesoporous silica nanoparticles for co-delivery of KAZ3 and MDR-1 siRNA. [1]

Publications

Ketan Ruparelia’s publications span pharmaceutical nanotechnology, cancer research, medicinal chemistry, and phytochemical analysis. His 2025 article on electrosprayed core-shell nanoparticles investigated KAZ3 and MDR-1 siRNA co-delivery for chemotherapy in multidrug-resistant colon cancer. [1] His other works examine synthetic resveratrol analogues, indanone-based chalcone analogues, plant secondary metabolism, and flavone tyrosinase inhibition. [2]

Research Impact

The reported bibliometric profile indicates 39 documents, 1,939 citations, and an h-index of 20. These figures provide quantitative indicators of scholarly visibility within the supplied profile, while the underlying publication record demonstrates activity across pharmaceutical delivery, cancer research, medicinal chemistry, and phytochemical investigation. In particular, nanoparticle-mediated siRNA delivery connects pharmaceutical formulation with cancer biology, whereas resveratrol analogue research links synthetic chemistry with anticancer investigation. [1][3]

Award Suitability

The documented research profile is relevant to a Research Excellence Award within a pharmaceutical research context because it encompasses multiple areas directly connected with drug development and cancer-oriented pharmaceutical science. The evidence includes peer-reviewed journal articles, DOI-indexed works, and research involving drug-delivery systems and anticancer compounds. [1][3]

Conclusion

Ketan Ruparelia’s documented research profile reflects interdisciplinary activity relevant to pharmaceutical and cancer research. His recorded works encompass nanocarrier-based siRNA delivery, anticancer resveratrol analogues, synthetic chemistry, phytochemical analysis, and enzyme-inhibitor research. The combination of these research areas provides a substantive scholarly basis for recognition under a pharmaceutical research excellence category.[1][3]

References

  1. Sayed, E., Ruparelia, K., Zafar, S., Faheem, A., Fatouros, D., Arshad, M. S., Singh, N., & Ahmad, Z. (2025). Novel electrosprayed core-shell polyethyleneimine and phospholipid coated MSNs for Co-delivery of KAZ3 and MDR-1 siRNA for efficient chemotherapy in multidrug-resistant colon cancer. European Journal of Pharmaceutics and Biopharmaceutics. https://doi.org/10.1016/j.ejpb.2025.114838
  2. Pal, P., Ruparelia, K. C., Arroo, R. R. J., & Brucoli, F. C. (2025). A Green Chemistry Approach for the Synthesis of Indanones as Fixed Ring Chalcone Analogues. Preprints. https://www.preprints.org/manuscript/202504.1089
  3. Ruparelia, K. C., Zeka, K., Beresford, K. J. M., Wilsher, N. E., Potter, G. A., Androutsopoulos, V. P., Brucoli, F., & Arroo, R. R. J. (2024). CYP1-Activation and Anticancer Properties of Synthetic Methoxylated Resveratrol Analogues. Molecules, 29(2). https://doi.org/10.3390/molecules29020423
  4. Arroo, R. R. J., Bhambra, A. S., Hano, C., Renda, G., Ruparelia, K. C., & Wang, M. F. (2021). Analysis of plant secondary metabolism using stable isotope-labelled precursors. Phytochemical Analysis. https://doi.org/10.1002/pca.2955
  5. Arroo, R. R. J., Sari, S., Barut, B., Özel, A., Ruparelia, K. C., & Şöhretoğlu, D. (2020). Flavones as tyrosinase inhibitors: kinetic studies in vitro and in silico. Phytochemical Analysis. https://doi.org/10.1002/pca.2897

jun ou | Nanomedicine | Best Academic Researcher Award

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jun ou | Nanomedicine | Best Academic Researcher Award

Prof. Dr. jun ou, Guilin University of Technology , China

Prof. Dr. Jun Ou is a renowned materials scientist specializing in biomaterials and nanotechnology. With a Ph.D. from Sichuan University, he serves as a professor at Guilin University of Technology. His expertise spans degradable bio-metals, upconversion nanomaterials, and smart drug delivery systems. He has served as a visiting scholar in Australia and Germany and has received multiple honors, including the Best Researcher Award 2023. Prof. Ou has published widely in high-impact journals and delivered talks at international conferences, contributing significantly to biomedical material innovation.

Publication Profile

Scopus

Education

Prof. Dr. Jun Ou is a distinguished academic with extensive qualifications in biomaterials and related fields. He earned his Ph.D. in Biomaterials from the University of Sichuan’s School of Materials Science and Engineering, where he studied from 2004 to 2010. Earlier, he completed his M.Sc. in Inorganic Chemistry at Guangxi Normal University between 2001 and 2003. His academic journey began with a Bachelor of Science in Engineering from the University of Science and Technology of Chengdu, where he studied from 1982 to 1986. His diverse academic background has laid a strong foundation for his contributions to the field of biomaterials.

Experience

Prof. Dr. Jun Ou has extensive teaching experience in Science and Engineering. From 2010 to 2022, he taught undergraduate and graduate courses at Guilin University of Technology, including “Introduction to Metallurgical Transmission Principles” and “Degradable Bio-Metal” focusing on novel ophthalmic materials. He designed course curricula, organized lectures, and graded assignments. As a professor, he has shared his expertise in Materials Science, Metallurgy, Physics, Inorganic Chemistry, Thermodynamics, and more, educating students worldwide. In addition, he has held visiting scholar positions, including at the Australian National University and Bundesanstalt für Materialforschung und-prüfung in Germany.

Awards

Prof. Dr. Jun Ou has received numerous prestigious awards and honors throughout his distinguished career. In 2023, he was honored with the Best Researcher Award at the International Research Awards on Advanced Nanomaterials and Nanotechnology. In 2022, he was named the Outstanding Open Science Author of the Year by Wiley-China. He also received the CSC Government of China Scholarship Council award in 2013 for his research project on rare earth nanomaterials and their application in constructing nano carbon monoxide carrier release systems, a three-year project that showcased his innovative contributions to nanotechnology and materials science.

Research Focus

Prof. Dr. Jun Ou is a prominent researcher in the field of luminescent materials and nanophosphors, with a specific focus on upconversion luminescence, optical temperature sensing, and lanthanide-doped materials. His work explores the design and enhancement of rare-earth-doped phosphors like NaYF₄: Yb, Ho and Er³⁺/Tm³⁺ systems for efficient green emission and thermometric applications. He also delves into nanoparticle-mediated nitric oxide delivery for biomedical applications like brain tumors. 🚀 His innovative use of Mn doping and 808 nm NIR excitation advances both materials science and nanomedicine, contributing significantly to next-gen optical sensors and bioimaging technologies.

Publication Top Notes

Synchronous realization of green upconversion emission enhancement and optical temperature sensitivity improvement in phosphors NaYF4: Yb, Ho via Mn doping

Promising lanthanide- NaYbF4:Er3+@NaYbF4:Tm3+ micro-phosphors for highly efficient upconversion luminescence and temperature sensing

Preliminary investigation of nitric oxide release from upconverted nanoparticles excited at 808 nm near-infrared for brain tumors

Corrigendum to “The synthesis of Er3+/Yb3+/K+ triple-doped NaYF4 phosphors and its high sensitivity optical thermometers at low power” J. Alloys Compd. 937 (March) (2023) 168299 (Journal of Alloys and Compounds (2023) 937, (S0925838822046904), (10.1016/j.jallcom.2022.168299))