Assoc. Prof. Dr. Jian Shi, Neurology of UCSF, United States
Assoc. Prof. Dr. Jian Shi is a distinguished neuroscientist at the University of California, San Francisco, with a Ph.D. in Neurobiology from Navy Medical University, China. ๐งฌ He completed postdoctoral training at the University of Texas Southwestern Medical Center, focusing on neuroscience. His research integrates brain injury, neurodegenerative diseases, and glioblastoma with cutting-edge AI and bioinformatics tools. ๐งช๐ง Dr. Shi has authored highly cited publications and received numerous accolades, including the APS Outstanding Paper Award. ๐ A dedicated mentor and educator, he actively contributes to diversity and public service in neurology and biomedical research.
Publication Profile
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Education
Assoc. Prof. Dr. Jian Shi began his academic journey at the National University of Defense Technology in Hunan Province, China, earning both his B.S. and M.S. degrees in Biomechanics. โ๏ธ๐ He then pursued his Ph.D. in Neurobiology under the mentorship of Dr. Lu Changlin at the prestigious Navy Medical University in Shanghai. ๐งฌ๐ฅ Driven by a passion for neuroscience, he completed his postdoctoral training at the University of Texas Southwestern Medical Center under the guidance of Dr. Steven G. Kernie, focusing on advanced neuroscience research. ๐ง ๐ฌ His academic foundation bridges biomechanics and cutting-edge neurobiological science.
Awards
Assoc. Prof. Dr. Jian Shi has received numerous accolades recognizing his excellence in research and education. ๐จ๐ณ He was honored with the prestigious National Award for Scientific Progress, Level 2 in China ๐ฅ๐ฌ and received the Award for Outstanding Scientists from Navy Medical University, where he also earned the Best Teacher Award for his commitment to academic excellence ๐จโ๐ซ๐. His groundbreaking work earned him the โTop 50 Most Cited Article Awardโ from the Journal of Clinical Medicine ๐๐ and the APS Outstanding Paper Award from Acta Pharmacologica Sinica ๐งช๐
. He is also recognized as a Trusted Reviewer by the International Journal of Molecular Sciences ๐ง โ
.
Research Focus
Assoc. Prof. Dr. Jian Shiโs research centers around neurobiology, with a strong emphasis on traumatic brain injury (TBI) ๐ง ๐ฅ, neurodegeneration ๐งฌ, neurogenesis ๐ฑ, and molecular neuroscience. His work explores small molecule therapies, microglial activation, intranasal drug delivery ๐, and microRNA biomarkers, particularly in the context of glioblastoma and stroke. He also investigates brain repair mechanisms, exosomal signaling ๐ฆ, and neurotrophin-mimetic compounds. In recent years, his interdisciplinary work has extended to climate impact models ๐ and machine learning applications ๐ค in brain science, reflecting a comprehensive and innovative research portfolio in translational neuroscience and brain health.
Publication Top Notes
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor
Intranasal administration with NAD+ profoundly decreases brain injury in a rat model of transient focal ischemia
Considering exosomal miR-21 as a biomarker for cancer
The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury
A small molecule p75NTRย ligand protects neurogenesis after traumatic brain injury
MicroRNAs as biomarkers for human glioblastoma: progress and potential
Regulatory networks between neurotrophins and miRNAs in brain diseases and cancers
Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimentalย โฆ
Beneficial effects of minocycline and botulinum toxinโinduced constraint physical therapy following experimental traumatic brain injury