University of Badji Mokhtar/Algeria

Author Profile

Early Academic Pursuits

Prof.Yamina Mohamed Ben Ali embarked on her academic journey with a fervent passion for computer science, which she nurtured at the esteemed Computer Science department of Badji Mokhtar University in Annaba, Algeria. Since 2015, she has been deeply involved in this field, immersing herself in various domains and disciplines, laying a robust foundation for her future endeavors.

Professional Endeavors

With a profound understanding of computer science, Yamina transitioned seamlessly into the role of a Research Scientist. Her professional journey has been marked by relentless dedication and a thirst for knowledge. Specializing in Machine Learning, Nature-Inspired Algorithms, Bioinformatics, Image Processing, and Steganography, she has explored the frontiers of these fields, pushing the boundaries of what is possible.

Contributions and Research Focus

Prof.Yamina's contributions to the field of computer science are multifaceted and impactful. Through her research, she has delved into the intricacies of machine learning, unraveling its potential applications across various industries. Her work on nature-inspired algorithms has paved the way for innovative problem-solving methodologies, drawing inspiration from the natural world to devise efficient solutions.

In bioinformatics, she has applied her expertise to analyze biological data, contributing significantly to advancements in genomics, proteomics, and beyond. Her proficiency in image processing and steganography has led to advancements in data security and digital forensics, safeguarding sensitive information in an increasingly digitized world.

Accolades and Recognition on Drug Discovery and Development

Prof.Yamina's tireless efforts and groundbreaking contributions have not gone unnoticed. She has been the recipient of numerous accolades and recognition from her peers and the academic community. Her work has been published in prestigious journals and presented at international conferences, solidifying her reputation as a leading authority in her field.

Drug discovery and development is a multifaceted process aimed at identifying new therapeutic agents and bringing them to market. It begins with the discovery phase, where researchers identify potential drug candidates through various methods, such as high-throughput screening of chemical libraries, computational drug design, and identification of active compounds from natural sources. This phase also involves target identification and validation, where the biological target of a drug is confirmed and its role in disease is understood. Once potential candidates are identified, lead compounds are optimized for their efficacy, selectivity, and pharmacokinetic properties through iterative cycles of synthesis and testing.

Impact and Influence

Prof.Yamina's work has had a profound impact on both academia and industry. By developing novel algorithms and methodologies, she has facilitated advancements in fields ranging from healthcare to cybersecurity. Her research has inspired countless researchers and practitioners, shaping the trajectory of computer science and its applications in the modern world.

Legacy and Future Contributions

Prof. Yamina Mohamed Ben Ali continues to chart new frontiers in computer science, her legacy grows evermore significant. Her pioneering research and unwavering commitment to excellence serve as a beacon for future generations of scientists and innovators. With her sights set on the future, she remains dedicated to pushing the boundaries of knowledge and spearheading transformative developments in her field.

In the years to come, Yamina's contributions are poised to leave an indelible mark on the landscape of computer science, propelling the discipline into new realms of possibility and driving meaningful change in society. With her passion, expertise, and vision, she is poised to shape the future of technology and inspire generations to come.

Following the discovery phase, drug development involves rigorous preclinical and clinical testing to ensure the safety and efficacy of the candidate drug. Preclinical testing includes in vitro and in vivo studies to evaluate the drug's biological activity and toxicity. If preclinical results are promising, the drug enters clinical trials, which are conducted in multiple phases. Phase I trials assess safety and dosage in healthy volunteers, Phase II trials evaluate efficacy and side effects in patients, and Phase III trials involve larger patient populations to confirm effectiveness and monitor adverse reactions. If the drug successfully passes all clinical trial phases, it undergoes regulatory review and approval before it can be marketed. This process, from discovery to market, typically spans over a decade and requires significant financial investment, but it is essential for ensuring that new drugs are safe and effective for patients.

Notable Publication

Anna Lahuta-Drug Delivery Systems-Best Researcher Award-1015

Posted on 27/05/202427/05/2024 by sciencefather

Dr.Anna Lahuta-Drug Delivery Systems-Best Researcher Award

V. N. Karazin Kharkiv National University-Ukrain

Author profile

Orcid

Early Academic Pursuits

Dr.Anna Lahuta's academic journey began in September 2007 at V.N. Karazin Kharkiv National University in Ukraine, where she embarked on a rigorous course of study in chemistry. During her tenure as a student, Lahuta demonstrated exceptional aptitude and passion for the subject, earning both her Bachelor's and Master's degrees. Her dedication to her studies was evident through her continuous pursuit of knowledge, culminating in her postgraduate studies at the same institution. This period was marked by intensive research and academic growth, setting a solid foundation for her future career in chemical sciences.

Professional Endeavors

In October 2019, Anna Lahuta achieved a significant milestone by earning the degree of Candidate of Chemical Sciences, equivalent to a Doctor of Philosophy (Ph.D.). This achievement marked her transition from a dedicated student to a recognized expert in her field. Her academic career progressed swiftly as she took on the role of a senior research fellow and associate professor at V.N. Karazin Kharkiv National University. Since 2017, Lahuta has been actively involved in teaching and research, contributing to the academic community with her expertise and innovative ideas.

Contributions and Research Focus

Dr.Anna Lahuta's research interests are broad and impactful, focusing on various aspects of chemical sciences. Her work often explores the intersection of chemistry with other scientific disciplines, leading to innovative and interdisciplinary research outcomes. Lahuta's participation in multiple international internships has significantly enriched her research perspective. In 2016, she interned at the University of Nice Sophia Antipolis in France, where she gained valuable international experience and exposure to different research methodologies. She further broadened her horizons through internships at Aston University in Birmingham, UK, in September 2017 and again in May-June 2022. These experiences allowed her to collaborate with global experts, enhancing her research capabilities and fostering international collaborations.

Accolades and Recognition

Dr.Anna Lahuta's contributions to the field of chemical sciences have not gone unnoticed. Her academic and research endeavors have earned her recognition within the scientific community. Although specific awards and honors are not detailed, her rapid advancement to the role of associate professor and her involvement in prestigious international programs speak volumes about her reputation and the respect she commands among her peers. Lahuta's participation in the spring school ‘Academic English and Digital Teaching Methods’ in Greece in April 2023 and the summer school on “Developing Research Skills” in Greece in September 2023 further highlight her commitment to continuous professional development and excellence in academia.

Impact and Influence on Drug Delivery Systems

Through her teaching and research, Anna Lahuta has significantly impacted the academic and scientific communities. Her role as an associate professor involves not only imparting knowledge to students but also mentoring and guiding the next generation of chemists. Her research contributions have likely influenced various chemical sciences fields, promoting advancements and new understandings. Moreover, her international experiences have enabled her to bring diverse perspectives and methodologies into her work, benefiting her students and colleagues.

Legacy and Future Contributions

Dr. Anna Lahuta continues her career, her legacy is being built on a foundation of dedication, innovation, and excellence. Her commitment to research and teaching ensures that she will remain a significant figure in chemical sciences. Looking ahead, Lahuta is poised to make further contributions that will advance the field and inspire future generations of scientists. Her ongoing professional development and international collaborations will likely lead to new research opportunities and breakthroughs, cementing her status as a leading expert in her domain.

Modern DDS are highly engineered to overcome biological barriers and achieve controlled release profiles. For example, liposomes, nanoparticles, and dendrimers can be designed to target specific cells or tissues, reducing systemic toxicity and improving drug accumulation at the disease site. Innovations like polymer-based drug delivery allow for sustained release, reducing the need for frequent dosing and improving patient compliance. Additionally, stimuli-responsive systems, which release drugs in response to environmental triggers like pH or temperature, offer dynamic control over drug administration. Overall, the development and refinement of drug delivery systems are critical for advancing personalized medicine and improving the efficacy of therapeutic interventions

Conclusion

Dr.Anna Lahuta's academic and professional journey is a testament to her dedication and passion for chemical sciences. From her early days as a student to her current role as an associate professor at V.N. Karazin Kharkiv National University, she has consistently demonstrated excellence and a commitment to advancing knowledge in her field. Her international experiences and continuous professional development reflect her desire to stay at the forefront of scientific research and education. As she continues to contribute to the academic community, her impact and influence will undoubtedly grow, leaving a lasting legacy for future scholars and researchers.

Drug delivery systems (DDS) are sophisticated technologies designed to transport therapeutic agents to targeted sites in the body, ensuring optimal efficacy and minimal side effects. These systems can range from simple mechanisms like controlled-release pills to advanced technologies such as nanocarriers and bioresponsive hydrogels. The primary goal of DDS is to improve the pharmacokinetics and pharmacodynamics of drugs, ensuring that they reach the intended site of action in the right concentration and at the right time. By doing so, these systems can enhance the therapeutic outcomes for patients, particularly in treating chronic diseases, cancers, and infections where precise delivery is crucial.

Notable Publications

The Spectrophotometric Determination of the Patchy Surface Potential of Viruses Using pH-Sensitive Molecular Probes

Thermostability of native DNA bound to TiO2 nanoparticles under physiological-like conditions

Influence of various colloidal surfactants on the stability of MS2 bacteriophage suspension. The charge distribution on the PCV2 virus surface

DNA:TiO2 nanoparticle nanoassemblies: effect of temperature and nanoparticle concentration on aggregation

Nagendra G-Drug Discovery and Development-Best Researcher Award-1013

Posted on 25/05/202425/05/2024 by sciencefather

Dr. Nagendra G-Drug Discovery and Development-Best Researcher Award

REVA University-India

Author Profile `

Early Academic Pursuits

Dr. Nagendra Govindappa embarked on his academic journey with a strong inclination towards chemistry, which led him to pursue a Ph.D. at Bangalore University under the mentorship of Dr. V. V. Sureshbabu. His doctoral research focused on the design and synthesis of novel peptidomimetics and related intermediates. Noteworthy achievements during this period include the insertion of thioamide linkage into peptide backbones and the synthesis of isoselenocyanates for the development of selenourea peptidomimetics. These endeavors laid the groundwork for his subsequent contributions to the field of peptide chemistry.

Professional Endeavors

Following his doctoral studies, Dr. Nagendra Govindappa continued his academic journey as an Associate Professor at REVA University, Bangalore. He expanded his research horizons through collaborations with esteemed institutions such as CSIR-IICT, Hyderabad, and TUD, Germany. His tenure at these institutions further enriched his expertise in synthetic chemistry, natural product synthesis, and chemical biology. Notable projects include the total synthesis of Cyclosporin-O, development of one-pot protocols for glycopeptide synthesis, and the synthesis of anti-cancer agents targeting EGFR family proteins.

Contributions and Research Focus

Dr. Nagendra Govindappa's research primarily revolves around the design, synthesis, and evaluation of peptides and peptidomimetics with diverse functionalities. He has pioneered the incorporation of various heterocycles such as oxadiazole, thiadiazole, tetrazole, and thiopeptides into peptide scaffolds, thereby expanding the chemical space of peptidomimetics. His innovative approaches have enabled the synthesis of bioactive molecules with potential applications in drug discovery and material science. Currently, he is focused on the total synthesis of natural peptides using advanced synthetic strategies and nanocatalysis.

Accolades and Recognition

Dr. Nagendra Govindappa's contributions to the field of peptide chemistry have garnered widespread recognition. He has published over 30 research articles in reputed journals, including notable contributions to journals with high impact factors. His research has been cited extensively, as evidenced by his impressive h-index of 12. Additionally, he holds two patents, underscoring the innovative nature of his work. His editorial appointments and professional memberships further signify his standing in the scientific community.

Impact and Influence on Drug Discovery and Development

Dr. Nagendra Govindappa's research has made significant contributions to the synthesis and functionalization of peptides and peptidomimetics. His work has not only expanded the synthetic toolbox available to chemists but has also provided insights into the structure-activity relationships of bioactive molecules. Moreover, his collaborations with international research groups have facilitated knowledge exchange and fostered scientific advancements on a global scale. His efforts have thus had a profound impact on the fields of chemistry and pharmaceutical sciences.

Following successful identification and optimization of lead compounds, the most promising candidates progress to preclinical development, where they undergo rigorous testing in laboratory and animal models to evaluate their safety and efficacy profiles. If a candidate demonstrates favorable results in preclinical studies, it advances to clinical development, which consists of a series of human trials designed to assess its safety, efficacy, and dosage regimen. Clinical trials are conducted in multiple phases, starting with small-scale Phase I trials to evaluate safety in healthy volunteers, followed by Phase II trials to assess efficacy and optimal dosage in patients with the target condition, and finally, Phase III trials to confirm safety and efficacy in larger patient populations. Upon successful completion of clinical trials, regulatory approval is sought, and if granted, the drug can be introduced to the market, where ongoing post-marketing surveillance ensures its continued safety and effectiveness.

Legacy and Future Contributions

As Dr. Nagendra Govindappa continues his academic journey, his legacy is poised to endure through his impactful research and mentorship. His innovative approaches to peptide synthesis and his dedication to advancing the frontiers of chemical biology serve as an inspiration to aspiring scientists. Moving forward, he aims to further explore the potential of peptidomimetics in drug discovery and materials science while nurturing the next generation of researchers through mentorship and collaboration. His unwavering commitment to scientific excellence ensures that his contributions will continue to shape the landscape of chemical research for years to come.

Drug discovery and development is a complex and multifaceted process aimed at identifying, synthesizing, and bringing to market new medications to address unmet medical needs or improve upon existing treatments. The process typically begins with target identification, where scientists pinpoint specific molecules, proteins, or pathways involved in a disease process that could serve as potential therapeutic targets. Once a target is identified, researchers embark on the drug discovery phase, which involves screening large libraries of compounds to find molecules that interact with the target in a desired way. This phase often employs techniques such as high-throughput screening and computer-aided drug design to identify promising lead compounds, which undergo further optimization to enhance their potency, selectivity, and pharmacokinetic properties.

Notable Publication

Sonia Kamboj – Pharmaceutical Chemistry – Excellence in Research-1011

Posted on 20/05/202420/05/2024 by sciencefather

Dr. Sonia Kamboj - Pharmaceutical Chemistry - Excellence in Research

Ch. Devi Lal College of Pharmacy Jagadhri Haryana - India

Author Profile

Scopus
Orcid

Early Academic Pursuits

Dr. Sonia Kamboj's academic journey began with a strong foundation in pharmaceutical sciences, marked by consistent excellence and dedication. She completed her 10th and 10+2 (Medical) from the Haryana Board of School Education with high marks, achieving 74.0% and 79.2%, respectively. These early achievements set the stage for her future academic pursuits.

Dr. Sonia's passion for pharmaceuticals led her to pursue a Bachelor of Pharmacy (B. Pharmacy) at Guru Gobind Singh College of Pharmacy, Yamunanagar, affiliated with Kurukshetra University (KUK). Graduating in July 2011 with a notable 72.7% and a first division, she demonstrated her commitment to the field. Her academic journey continued with a Master of Pharmacy (M. Pharmacy) in Pharmaceutical Analysis from I.S.F College of Pharmacy, Moga, Punjab, affiliated with Punjab Technical University (PTU) Jalandhar. In September 2013, she graduated with distinction, securing a remarkable 79.5% and earning the prestigious gold medal.

Dr. Sonia's academic journey culminated in a PhD in Pharmaceutical Sciences from MM College of Pharmacy, Mullana (MMDU, Mullana). Her PhD thesis, "Synthesis and Biological Evaluation of New Chromane and its Analogues," reflects her deep engagement with pharmaceutical research and her drive to contribute to the scientific community.

Professional Endeavors

Dr. Sonia Kamboj has made significant strides in her professional career, contributing to the field of pharmaceutical sciences both as an educator and a researcher. She began her professional journey as an Associate Professor at Ch. Devi Lal College of Pharmacy (CDLCOP), Bhagwangarh, Jagadhri, Haryana, in August 2013. Over the course of more than a decade, she has accumulated extensive experience, sharing her knowledge and expertise with students and colleagues alike.

In addition to her teaching responsibilities, Sonia has held several administrative positions. She is a member of the Academic Committee at CDLCOP, demonstrating her commitment to academic excellence and curriculum development. Her involvement extends to professional organizations as well, where she is a member of the Association of Pharmaceutical Teachers of India (APTI), the Indian Pharmacy Graduates Association (IPGA), and the Chinese Chemical Society. Moreover, she has served as an external examiner at Pt B.D. Sharma University, Rohtak, further showcasing her expertise in pharmaceutical sciences.

Contributions and Research Focus

Dr. Sonia Kamboj's research contributions are substantial and varied, reflecting her broad interests within pharmaceutical sciences. Her PhD research focused on the synthesis and biological evaluation of new chromane and its analogues, a project that underscores her commitment to advancing pharmaceutical knowledge. Her M.Pharm project involved the analytical method development and validation for the simultaneous estimation of berberine and curcumin in plant extracts and polyherbal formulations, highlighting her proficiency in analytical techniques and her interest in herbal drug standardization.

Sonia has also contributed to quality analysis in pharmaceutical settings. During her time as an M.Pharm student at ISF Analytical Laboratory (ISFAL) in Moga, Punjab, she performed quality analysis of various drugs, demonstrating her practical skills and attention to detail. Her involvement in quality control and quality assurance during her B.Pharm studies, as well as her technical duties at Ranbaxy Laboratories Limited, further highlight her hands-on experience in the pharmaceutical industry.

Her technical proficiency spans a wide range of analytical methods and instrumental skills, including HPLC, HPTLC, UV-Visible Spectrophotometry, and molecular docking. This technical expertise has been instrumental in her research and teaching, allowing her to guide students effectively in these areas.

Accolades and Recognition

Dr. Sonia Kamboj's achievements have been recognized through various awards and accolades. She received a gold medal from PTU Jalandhar for her outstanding performance in her M.Pharm degree. Additionally, she was awarded the Graduate Pharmacy Aptitude Test (GPAT) Scholarship in 2011, supporting her postgraduate studies in pharmaceutical analysis. Her excellence in research has been acknowledged with the first prize in poster presentation at the ABT-sponsored international conference organized by M.M. College of Pharmacy in February 2024.

Impact and Influence on Pharmaceutical Chemistry

Dr. Sonia Kamboj's impact extends beyond her immediate academic and professional environment. As a resource person, she has been invited to speak on topics such as women empowerment and equity, and has addressed audiences at institutions like Guru Gobind Singh College of Pharmacy and Govt. Middle School Rattangarh, Radaur, Haryana. Her role as a reviewer for scientific manuscripts in reputable journals, including Current Medicinal Chemistry and the Arabian Journal for Science and Engineering, further underscores her influence in the scientific community.

The ultimate goal of pharmaceutical chemistry is to develop new medications that improve health outcomes and quality of life for patients. This field plays a critical role in addressing a myriad of health challenges, from infectious diseases to chronic conditions like diabetes and cancer. By exploring the molecular mechanisms of disease and devising novel therapeutic strategies, pharmaceutical chemists contribute significantly to the advancement of medicine. Their work not only leads to the creation of new drugs but also enhances our understanding of how existing drugs work, paving the way for improved formulations and delivery systems. In essence, pharmaceutical chemistry is a cornerstone of modern healthcare, driving innovations that translate scientific discoveries into tangible health benefits.

Legacy and Future Contributions

Looking ahead, Sonia Kamboj aims to continue her contributions to pharmaceutical sciences through ongoing research, teaching, and professional engagement. Her extensive list of publications, patents, and conference presentations reflects her dedication to advancing the field. Her work on the synthesis and evaluation of novel pharmaceutical compounds, as well as her expertise in analytical methods, positions her as a significant contributor to future developments in pharmaceutical research and education.

Sonia's legacy is marked by her commitment to excellence, her dedication to knowledge sharing, and her passion for advancing pharmaceutical sciences. As she continues to explore new frontiers in her research and professional endeavors, she remains a valuable asset to the academic and scientific communities. Her future contributions will undoubtedly continue to impact the field, fostering innovation and inspiring the next generation of pharmaceutical scientists.

Pharmaceutical chemistry is a dynamic field at the intersection of chemistry and pharmacology, dedicated to the design, synthesis, and development of bioactive compounds into safe and effective therapeutic agents. This discipline encompasses a wide range of activities, including the identification of new chemical entities, the optimization of lead compounds, and the formulation of drugs. It integrates principles from organic chemistry, biochemistry, and molecular biology to understand and manipulate the chemical nature of drugs and their interactions with biological systems. Researchers in pharmaceutical chemistry engage in the rigorous process of drug discovery, which involves high-throughput screening, structure-activity relationship (SAR) studies, and computer-aided drug design (CADD) to identify promising candidates for development.